| Entry |
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| Gene name |
TK2, MTDPS2, MTTK
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| Definition |
thymidine kinase 2, mitochondrial (EC:2.7.1.21)
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| Orthology |
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| Organism |
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| Pathway |
| Pyrimidine metabolism | | Drug metabolism - other enzymes | | Metabolic pathways |
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| Disease |
| Mitochondrial DNA depletion syndrome (MDS) |
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| Class |
Metabolism; Nucleotide metabolism; Pyrimidine metabolism [PATH: hsa00240]
Metabolism; Xenobiotics biodegradation and metabolism; Drug metabolism - other enzymes [PATH: hsa00983]
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| SSDB |
   |
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| Motif |
 |
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| Other DBs |
NCBI-GI: NCBI-GeneID: OMIM: HGNC: HPRD: Ensembl: UniProt: |
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| Position |
16q22-q23.1
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| AA seq |
234 aa  
MGAFCQRPSSDKEQEKEKKSVICVEGNIASGKTTCLEFFSNATDVEVLTEPVSKWRNVRG
HNPLGLMYHDASRWGLTLQTYVQLTMLDRHTRPQVSSVRLMERSIHSARYIFVENLYRSG
KMPEVDYVVLSEWFDWILRNMDVSVDLIVYLRTNPETCYQRLKKRCREEEKVIPLEYLEA
IHHLHEEWLIKGSLFPMAAPVLVIEADHHMERMLELFEQNRDRILTPENRKHCP |
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| NT seq |
705 nt  +upstreamnt +downstreamnt
atgggtgcgttctgccagcgtcctagcagtgataaagaacaggaaaaagagaaaaaatca
gtgatctgtgtcgagggcaatattgcaagtgggaagacgacatgcctggaattcttctcc
aacgcgacagacgtcgaggtgttaacggagcctgtgtccaagtggagaaatgtccgtggc
cacaatcctctgggcctgatgtaccacgatgcctctcgctggggtcttacgctacagact
tatgtgcagctcaccatgctggacaggcatactcgtcctcaggtgtcatctgtacggttg
atggagaggtcgattcacagcgcaagatacatttttgtagaaaacctgtatagaagtggg
aagatgccagaagtggactatgtagttctgtcggaatggtttgactggatcttgaggaac
atggacgtgtctgttgatttgatagtttaccttcggaccaatcctgagacttgttaccag
aggttaaagaagagatgcagggaagaggagaaggtcattccgctggaatacctggaagca
attcaccatctccatgaggagtggctcatcaaaggcagccttttccccatggcagcccct
gttctggtgattgaggctgaccaccacatggagaggatgttagaactctttgaacaaaat
cgggatcgaatattaactccagagaatcggaagcattgcccatag |
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