KEGG   Homo sapiens (human): 7108
Entry
7108              CDS       T01001                                 
Symbol
TM7SF2, ANG1, C14SR, DHCR14A, NET47
Name
(RefSeq) transmembrane 7 superfamily member 2
  KO
K00222  Delta14-sterol reductase [EC:1.3.1.70]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00100  Steroid biosynthesis
hsa01100  Metabolic pathways
Module
hsa_M00101  Cholesterol biosynthesis, FPP => cholesterol
Network
nt06034  Cholesterol biosynthesis
  Element
N01624  Cholesterol biosynthesis
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09103 Lipid metabolism
   00100 Steroid biosynthesis
    7108 (TM7SF2)
Enzymes [BR:hsa01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.70  Delta14-sterol reductase
     7108 (TM7SF2)
SSDB
Motif
Pfam: ERG4_ERG24 DUF1295 ICMT PEMT
Other DBs
NCBI-GeneID: 7108
NCBI-ProteinID: NP_003264
OMIM: 603414
HGNC: 11863
Ensembl: ENSG00000149809
UniProt: O76062
Position
11:65111872..65116230
AA seq 418 aa
MAPTQGPRAPLEFGGPLGAAALLLLLPATMFHLLLAARSGPARLLGPPASLPGLEVLWSP
RALLLWLAWLGLQAALYLLPARKVAEGQELKDKSRLRYPINGFQALVLTALLVGLGMSAG
LPLGALPEMLLPLAFVATLTAFIFSLFLYMKAQVAPVSALAPGGNSGNPIYDFFLGRELN
PRICFFDFKYFCELRPGLIGWVLINLALLMKEAELRGSPSLAMWLVNGFQLLYVGDALWH
EEAVLTTMDITHDGFGFMLAFGDMAWVPFTYSLQAQFLLHHPQPLGLPMASVICLINATG
YYIFRGANSQKNTFRKNPSDPRVAGLETISTATGRKLLVSGWWGMVRHPNYLGDLIMALA
WSLPCGVSHLLPYFYLLYFTALLVHREARDERQCLQKYGLAWQEYCRRVPYRIMPYIY
NT seq 1257 nt   +upstreamnt  +downstreamnt
atggcccccactcagggcccccgggccccgctggaattcggagggcccctgggcgccgcg
gctctgctactgctgctgcccgccaccatgttccacctgctcctggcggcccgttcgggc
cccgcgcgcctgctgggtccacccgcgtccctgccggggctggaggtgctgtggagccca
cgggcgctgctgctgtggctcgcctggctcggcctgcaggcggcgctctacctactgccg
gcgcgcaaggtggccgaggggcaggaattgaaggacaagagtcgcctgcgctatcctatt
aacggcttccaggccctggtgctgacagccctgttggtggggctggggatgtcagcgggg
ctgcctctgggggcgctcccggaaatgctcctgcccttggcgtttgtcgccaccctcacc
gctttcatcttcagcctctttctctacatgaaggcgcaggtagccccagtttcggccctg
gcacctggggggaactcaggcaatccgatttacgacttttttctgggacgagagctcaac
cctcgtatctgtttcttcgacttcaaatatttctgtgaactgcgacccggcctcatcggc
tgggtcctcatcaacctggccctgttgatgaaggaggcagagcttcgaggcagtccctca
ctggccatgtggctggtcaatggcttccagttgctctacgtgggtgatgccctctggcac
gaggaggccgtcctcaccaccatggatatcacacatgacgggtttggcttcatgctggcg
tttggggacatggcctgggtgcccttcacctacagcctgcaggcccagttcctgctgcac
cacccgcagcccctggggttgcccatggcctctgtcatctgcctcatcaatgctactggt
tactacatcttccgtggggcgaattcccagaaaaacactttccgaaagaatccttctgac
cccagagtggctgggcttgagaccatctctacagccacagggcggaaactgctggtgtct
gggtggtggggtatggtccgccatcccaactatcttggagacctcatcatggctctggct
tggtccttgccctgcggggtgtcacacctgctgccctacttctacctcctctacttcacc
gcgctgctggtgcaccgtgaggcccgggatgagcggcagtgcctgcagaagtacggcctg
gcctggcaggagtactgccggcgtgtgccttaccgcatcatgccctacatctactga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (5)   
   KEGG PATHWAY (2)   
   KEGG MODULE (3)   
Network (2)   
   KEGG NETWORK (2)   
Disease (1)   
   OMIM (1)   
Chemical substance (7)   
   KEGG COMPOUND (7)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (13)   
   KEGG ORTHOLOGY (1)   
   RefGene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (4)   
   OC (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (19)   
   RefSeq(nuc) (3)   
   GenBank (8)   
   EMBL (8)   
Protein domain (4)   
   Pfam (4)   
All databases (61)   

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