KEGG T01001: 7357

Homo sapiens (human): 7357

Entry

7357 CDS T01001

Gene name

UGCG, GCS, GLCT1

Definition

UDP-glucose ceramide glucosyltransferase (EC:2.4.1.80)

Orthology

K00720

ceramide glucosyltransferase [EC:2.4.1.80]

Organism

hsa Homo sapiens (human)

Pathway

hsa00600	Sphingolipid metabolism
hsa01100	Metabolic pathways

Module

hsa_M00066

Lactosylceramide biosynthesis

Drug target

Miglustat:

D05032

Other:

D09893 D09894

Class

Metabolism; Lipid metabolism; Sphingolipid metabolism [PATH:hsa00600]

SSDB

Motif

Pfam:

Glyco_transf_21 Glyco_tranf_2_3 Glyco_trans_2_3 Glycos_transf_2 Chitin_synth_2

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

UniProt:

Position

9q31

AA seq 394 aa
MALLDLALEGMAVFGFVLFLVLWLMHFMAIIYTRLHLNKKATDKQPYSKLPGVSLLKPLK
GVDPNLINNLETFFELDYPKYEVLLCVQDHDDPAIDVCKKLLGKYPNVDARLFIGGKKVG
INPKINNLMPGYEVAKYDLIWICDSGIRVIPDTLTDMVNQMTEKVGLVHGLPYVADRQGF
AATLEQVYFGTSHPRYYISANVTGFKCVTGMSCLMRKDVLDQAGGLIAFAQYIAEDYFMA
KAIADRGWRFAMSTQVAMQNSGSYSISQFQSRMIRWTKLRINMLPATIICEPISECFVAS
LIIGWAAHHVFRWDIMVFFMCHCLAWFIFDYIQLRGVQGGTLCFSKLDYAVAWFIRESMT
IYIFLSALWDPTISWRTGRYRLRCGGTAEEILDV

NT seq 1185 nt +upstreamnt +downstreamnt
atggcgctgctggacctggccttggagggaatggccgtcttcgggttcgtcctcttcttg
gtgctgtggctgatgcatttcatggctatcatctacacccgattacacctcaacaagaag
gcaactgacaaacagccttatagcaagctcccaggtgtctctcttctgaaaccactgaaa
ggggtagatcctaacttaatcaacaacctggaaacattctttgaattggattatcccaaa
tatgaagtgctcctttgtgtacaagatcatgatgatccagccattgatgtatgtaagaag
cttcttggaaaatatccaaatgttgatgctagattgtttataggtggtaaaaaagttggc
attaatcctaaaattaataatttaatgccaggatatgaagttgcaaagtatgatcttata
tggatttgtgatagtggaataagagtaattccagatacgcttactgacatggtgaatcaa
atgacagaaaaagtaggcttggttcacgggctgccttacgtagcagacagacagggcttt
gctgccaccttagagcaggtatattttggaacttcacatccaagatactatatctctgcc
aatgtaactggtttcaaatgtgtgacaggaatgtcttgtttaatgagaaaagatgtgttg
gatcaagcaggaggacttatagcttttgctcagtacattgccgaagattactttatggcc
aaagcgatagctgaccgaggttggaggtttgcaatgtccactcaagttgcaatgcaaaac
tctggctcatattcaatttctcagtttcaatccagaatgatcaggtggaccaaactacga
attaacatgcttcctgctacaataatttgtgagccaatttcagaatgctttgttgccagt
ttaattattggatgggcagcccaccatgtgttcagatgggatattatggtatttttcatg
tgtcattgcctggcatggtttatatttgactacattcaactcaggggtgtccagggtggc
acactgtgtttttcaaaacttgattatgcagtcgcctggttcatccgcgaatccatgaca
atatacatttttttgtctgcattatgggacccaactataagctggagaactggtcgctac
agattacgctgtgggggtacagcagaggaaatcctagatgtataa

All links

Ontology (4)   
   KEGG BRITE (4)   
Pathway (3)   
   KEGG PATHWAY (2)   
   KEGG MODULE (1)   
Disease (1)   
   OMIM (1)   
Drug (3)   
   KEGG DRUG (3)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (12)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (5)   
   UniGene (2)   
   HGNC (1)   
   HPRD (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (11)   
   RefSeq(nuc) (1)   
   GenBank (5)   
   EMBL (5)   
Protein domain (5)   
   Pfam (5)   
All databases (48)   

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