| Entry |
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| Gene name |
UROS, UROIIIS
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| Definition |
uroporphyrinogen III synthase (EC:4.2.1.75)
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| Orthology |
| uroporphyrinogen-III synthase [EC: 4.2.1.75] |
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| Organism |
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| Pathway |
| Porphyrin and chlorophyll metabolism | | Metabolic pathways |
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| Disease |
| Erythropoietic porphyria (EP) |
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| Class |
Metabolism; Metabolism of cofactors and vitamins; Porphyrin and chlorophyll metabolism [PATH: hsa00860]
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| SSDB |
   |
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| Motif |
 |
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| Other DBs |
NCBI-GI: NCBI-GeneID: OMIM: HGNC: HPRD: Ensembl: Vega: UniProt: |
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| Structure |
PDB: |
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| Position |
10q25.2-q26.3
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| AA seq |
265 aa  
MKVLLLKDAKEDDCGQDPYIRELGLYGLEATLIPVLSFEFLSLPSFSEKLSHPEDYGGLI
FTSPRAVEAAELCLEQNNKTEVWERSLKEKWNAKSVYVVGNATASLVSKIGLDTEGETCG
NAEKLAEYICSRESSALPLLFPCGNLKREILPKALKDKGIAMESITVYQTVAHPGIQGNL
NSYYSQQGVPASITFFSPSGLTYSLKHIQELSGDNIDQIKFAAIGPTTARALAAQGLPVS
CTAESPTPQALATGIRKALQPHGCC |
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| NT seq |
798 nt  +upstreamnt +downstreamnt
atgaaggttcttttactgaaggatgcgaaggaagatgactgtggccaggatccgtatatc
agggaattaggattatatggacttgaagccactttgatccctgttttatcgtttgagttt
ttgtctcttcccagtttctctgagaagctttctcatcctgaagattacgggggactcatt
tttaccagccccagagcagtggaagcagcagagttatgtttggagcaaaacaataaaact
gaagtctgggaaaggtctctgaaagaaaaatggaatgccaagtcagtgtatgtggttgga
aatgctactgcttctctagtgagtaaaattggcctggatacagaaggagaaacctgtgga
aatgcagaaaagcttgcagaatatatttgttccagggagtcctcagcactgcctcttcta
tttccctgtggaaacctcaaaagagaaatcctgccaaaagcgctcaaggacaaagggatt
gccatggaaagcataactgtgtatcagacagttgcacacccaggaatccaagggaacctg
aacagctactattcccagcagggggttccagccagcatcacattttttagtccctctggc
ctcacatacagtctcaagcacattcaggagttatctggtgacaatatcgatcaaattaag
tttgcagccatcggccccactacggctcgcgcgctggccgcccagggccttcctgtaagc
tgcactgcagagagccccacgccacaagccctggccactggcatcaggaaggctctccag
ccccatggctgctgctga |
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