KEGG T01001: 7514

Homo sapiens (human): 7514

Entry

7514 CDS T01001

Gene name

XPO1, CRM1, emb, exp1

Definition

exportin 1 (CRM1 homolog, yeast)

Orthology

K14290

exportin-1

Organism

hsa Homo sapiens (human)

Pathway

hsa03008	Ribosome biogenesis in eukaryotes
hsa03013	RNA transport
hsa05164	Influenza A
hsa05166	HTLV-I infection
hsa05169	Epstein-Barr virus infection

Class

Genetic Information Processing; Translation; RNA transport [PATH:hsa03013]
Genetic Information Processing; Translation; Ribosome biogenesis in eukaryotes [PATH:hsa03008]
Human Diseases; Infectious diseases; HTLV-I infection [PATH:hsa05166]
Human Diseases; Infectious diseases; Influenza A [PATH:hsa05164]
Human Diseases; Infectious diseases; Epstein-Barr virus infection [PATH:hsa05169]

SSDB

Motif

Pfam:

CRM1_C Xpo1 IBN_N

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

Structure

PDB:

3GB8 2L1L 1W9C

Position

2p15

AA seq 1071 aa
MPAIMTMLADHAARQLLDFSQKLDINLLDNVVNCLYHGEGAQQRMAQEVLTHLKEHPDAW
TRVDTILEFSQNMNTKYYGLQILENVIKTRWKILPRNQCEGIKKYVVGLIIKTSSDPTCV
EKEKVYIGKLNMILVQILKQEWPKHWPTFISDIVGASRTSESLCQNNMVILKLLSEEVFD
FSSGQITQVKSKHLKDSMCNEFSQIFQLCQFVMENSQNAPLVHATLETLLRFLNWIPLGY
IFETKLISTLIYKFLNVPMFRNVSLKCLTEIAGVSVSQYEEQFVTLFTLTMMQLKQMLPL
NTNIRLAYSNGKDDEQNFIQNLSLFLCTFLKEHDQLIEKRLNLRETLMEALHYMLLVSEV
EETEIFKICLEYWNHLAAELYRESPFSTSASPLLSGSQHFDVPPRRQLYLPMLFKVRLLM
VSRMAKPEEVLVVENDQGEVVREFMKDTDSINLYKNMRETLVYLTHLDYVDTERIMTEKL
HNQVNGTEWSWKNLNTLCWAIGSISGAMHEEDEKRFLVTVIKDLLGLCEQKRGKDNKAII
ASNIMYIVGQYPRFLRAHWKFLKTVVNKLFEFMHETHDGVQDMACDTFIKIAQKCRRHFV
QVQVGEVMPFIDEILNNINTIICDLQPQQVHTFYEAVGYMIGAQTDQTVQEHLIEKYMLL
PNQVWDSIIQQATKNVDILKDPETVKQLGSILKTNVRACKAVGHPFVIQLGRIYLDMLNV
YKCLSENISAAIQANGEMVTKQPLIRSMRTVKRETLKLISGWVSRSNDPQMVAENFVPPL
LDAVLIDYQRNVPAAREPEVLSTMAIIVNKLGGHITAEIPQIFDAVFECTLNMINKDFEE
YPEHRTNFFLLLQAVNSHCFPAFLAIPPTQFKLVLDSIIWAFKHTMRNVADTGLQILFTL
LQNVAQEEAAAQSFYQTYFCDILQHIFSVVTDTSHTAGLTMHASILAYMFNLVEEGKIST
SLNPGNPVNNQIFLQEYVANLLKSAFPHLQDAQVKLFVTGLFSLNQDIPAFKEHLRDFLV
QIKEFAGEDTSDLFLEEREIALRQADEEKHKRQMSVPGIFNPHEIPEEMCD

NT seq 3216 nt +upstreamnt +downstreamnt
atgccagcaattatgacaatgttagcagaccatgcagctcgtcagctgcttgatttcagc
caaaaactggatatcaacttattagataatgtggtgaattgcttataccatggagaagga
gcccagcaaagaatggctcaagaagtactgacacatttaaaggagcatcctgatgcttgg
acaagagtcgacacaattttggaattttctcagaatatgaatacgaaatactatggacta
caaattttggaaaatgtgataaaaacaaggtggaagattcttccaaggaaccagtgcgaa
ggaataaaaaaatacgttgttggcctcattatcaagacgtcatctgacccaacttgtgta
gagaaagaaaaggtgtatatcggaaaattaaatatgatccttgttcagatactgaaacaa
gaatggcccaaacattggccaacttttatcagtgatattgttggagcaagtaggaccagc
gaaagtctctgtcaaaataatatggtgattcttaaactcttgagtgaagaagtatttgat
ttctctagtggacagataacccaagtcaaatctaagcatttaaaagacagcatgtgcaat
gaattctcacagatatttcaactgtgtcagtttgtaatggaaaattctcaaaatgctcca
cttgtacatgcaaccttggaaacattgctcagatttctgaactggattcccctgggatat
atttttgagaccaaattaatcagcacattgatttataagttcctgaatgttccaatgttt
cgaaatgtctctctgaagtgcctcactgagattgctggtgtgagtgtaagccaatatgaa
gaacaatttgtaacactatttactctgacaatgatgcaactaaagcagatgcttccttta
aataccaatattcgacttgcgtactcaaatggaaaagatgatgaacagaacttcattcaa
aatctcagtttgtttctctgcacctttcttaaggaacatgatcaacttatagaaaaaaga
ttaaatctcagggaaactcttatggaggcccttcattatatgttgttggtatctgaagta
gaagaaactgaaatctttaaaatttgtcttgaatactggaatcatttggctgctgaactc
tatagagagagtccattctctacatctgcctctccgttgctttctggaagtcaacatttt
gatgttcctcccaggagacagctatatttgcccatgttattcaaggtccgtttattaatg
gttagtcgaatggctaaaccagaggaagtattggttgtagagaatgatcaaggagaagtt
gtgagagaattcatgaaggatacagattccataaatttgtataagaatatgagggaaaca
ttggtttatcttactcatctggattatgtagatacagaaagaataatgacagagaagctt
cacaatcaagtgaatggtacagagtggtcatggaaaaatttgaatacattgtgttgggca
ataggctccattagtggagcaatgcatgaagaggacgaaaaacgatttcttgttactgtt
ataaaggatctattaggattatgtgaacagaaaagaggcaaagataataaagctattatt
gcatcaaatatcatgtacatagtaggtcaatacccacgttttttgagagctcactggaaa
tttctgaagactgtagttaacaagctgttcgaattcatgcatgagacccatgatggagtc
caggatatggcttgtgatactttcattaaaatagcccaaaaatgccgcaggcatttcgtt
caggttcaggttggagaagtgatgccatttattgatgaaattttgaacaacattaacact
attatttgtgatcttcagcctcaacaggttcatacgttttatgaagctgtggggtacatg
attggtgcacaaacagatcaaacagtacaagaacacttgatagaaaagtacatgttactc
cctaatcaagtgtgggatagtataatccagcaggcaaccaaaaatgtggatatactgaaa
gatcctgaaacagtcaagcagcttggtagcattttgaaaacaaatgtgagagcctgcaaa
gctgttggacacccctttgtaattcagcttggaagaatttatttagatatgcttaatgta
tacaagtgcctcagtgaaaatatttctgcagctatccaagctaatggtgaaatggttaca
aagcaaccattgattagaagtatgcgaactgtaaaaagggaaactttaaagttaatatct
ggttgggtgagccgatccaatgatccacagatggtcgctgaaaattttgttccccctctg
ttggatgcagttctcattgattatcagagaaatgtcccagctgctagagaaccagaagtg
cttagtactatggccataattgtcaacaagttagggggacatataacagctgaaatacct
caaatatttgatgctgtttttgaatgcacattgaatatgataaataaggactttgaagaa
tatcctgaacatagaacgaactttttcttactacttcaggctgtcaattctcattgtttc
ccagcattccttgctattccacctacacagtttaaacttgttttggattccatcatttgg
gctttcaaacatactatgaggaatgtcgcagatacgggcttacagatactttttacactc
ttacaaaatgttgcacaagaagaagctgcagctcagagtttttatcaaacttatttttgt
gatattctccagcatatcttttctgttgtgacagacacttcacatactgctggtttaaca
atgcatgcatcaattcttgcatatatgtttaatttggttgaagaaggaaaaataagtaca
tcattaaatcctggaaatccagttaacaaccaaatctttcttcaggaatatgtggctaat
ctccttaagtcggccttccctcacctacaagatgctcaagtaaagctctttgtgacaggg
cttttcagcttaaatcaagatattcctgctttcaaggaacatttaagagatttcctagtt
caaataaaggaatttgcaggtgaagacacttctgatttgtttttggaagagagagaaata
gccctacggcaggctgatgaagagaaacataaacgtcaaatgtctgtccctggcatcttt
aatccacatgagattccagaagaaatgtgtgattaa

All links

Pathway (5)   
   KEGG PATHWAY (5)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (19)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (11)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (3)   
   UniProt (2)   
   RefSeq(pep) (1)   
DNA sequence (33)   
   RefSeq(nuc) (1)   
   GenBank (16)   
   EMBL (16)   
3D Structure (3)   
   PDB (3)   
Protein domain (3)   
   Pfam (3)   
All databases (68)   

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