KEGG T01001: 7786

Homo sapiens (human): 7786

Entry

7786 CDS T01001

Gene name

MAP3K12, DLK, MEKK12, MUK, ZPK, ZPKP1

Definition

mitogen-activated protein kinase kinase kinase 12 (EC:2.7.11.25)

Orthology

K04423

mitogen-activated protein kinase kinase kinase 12 [EC:2.7.11.25]

Organism

hsa Homo sapiens (human)

Pathway

hsa04010

MAPK signaling pathway

Class

Environmental Information Processing; Signal transduction; MAPK signaling pathway [PATH:hsa04010]

SSDB

Motif

Pfam:

Pkinase_Tyr Pkinase Kinase-like HAUS-augmin3

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

Position

12q13

AA seq 892 aa
MACLHETRTPSPSFGGFVSTLSEASMRKLDPDTSDCTPEKDLTPTQCVLRDVVPLGGQGG
GGPSPSPGGEPPPEPFANSVLQLHEQDAGGPGGAAGSPESRASRVRADEVRLQCQSGSGF
LEGLFGCLRPVWTMIGKAYSTEHKQQQEDLWEVPFEEILDLQWVGSGAQGAVFLGRFHGE
EVAVKKVRDLKETDIKHLRKLKHPNIITFKGVCTQAPCYCILMEFCAQGQLYEVLRAGRP
VTPSLLVDWSMGIAGGMNYLHLHKIIHRDLKSPNMLITYDDVVKISDFGTSKELSDKSTK
MSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIPYKDVDSSAIIWGVGSNSL
HLPVPSSCPDGFKILLRQCWNSKPRNRPSFRQILLHLDIASADVLSTPQETYFKSQAEWR
EEVKLHFEKIKSEGTCLHRLEEELVMRRREELRHALDIREHYERKLERANNLYMELNALM
LQLELKERELLRREQALERRCPGLLKPHPSRGLLHGNTMEKLIKKRNVPQKLSPHSKRPD
ILKTESLLPKLDAALSGVGLPGCPKGPPSPGRSRRGKTRHRKASAKGSCGDLPGLRTAVP
PHEPGGPGSPGGLGGGPSAWEACPPALRGLHHDLLLRKMSSSSPDLLSAALGSRGRGATG
GAGDPGSPPPARGDTPPSEGSAPGSTSPDSPGGAKGEPPPPVGPGEGVGLLGTGREGTSG
RGGSRAGSQHLTPAALLYRAAVTRSQKRGISSEEEEGEVDSEVELTSSQRWPQSLNMRQS
LSTFSSENPSDGEEGTASEPSPSGTPEVGSTNTDERPDERSDDMCSQGSEIPLDPPPSEV
IPGPEPSSLPIPHQELLRERGPPNSEDSDCDSTELDNSNSVDALRPPASLPP

NT seq 2679 nt +upstreamnt +downstreamnt
atggcttgcctccatgagacccgaacaccctctccttcctttgggggctttgtgtctacc
ctaagtgaggcatccatgcgcaagctggacccagacacttctgactgcactcccgagaag
gacctgacgcctacccagtgtgtacttcgagatgtggtaccccttggtgggcagggtggg
ggagggcccagcccctccccaggtggagagccgccccctgagccttttgccaacagtgtc
ctgcagctacatgagcaggatgcagggggcccagggggagcagctgggtcacctgagagt
cgggcatccagagttcgagctgacgaggtgcgactgcagtgccagagtggcagtggcttc
cttgagggcctctttggctgcctgcgccctgtctggaccatgattggcaaagcctactcc
actgagcacaagcagcagcaggaagacctttgggaggtcccctttgaggaaatcctggac
ctgcagtgggtgggctcaggggcccagggtgctgtcttcctggggcgcttccacggggag
gaggtggctgtgaagaaggtgcgagacctcaaagaaaccgacatcaagcacttgcgaaag
ctgaagcaccccaacatcatcactttcaagggtgtgtgcacccaggctccctgctactgc
atcctcatggagttctgcgcccagggccagctgtatgaggtactgcgggctggccgccct
gtcaccccctccttactggttgactggtccatgggcatcgctggtggcatgaactacctg
cacctgcacaagattatccacagggatctcaagtcacccaacatgctaatcacctacgac
gatgtggtgaagatctcagattttggcacttccaaggagctgagtgacaagagcaccaag
atgtcctttgcagggacagtagcctggatggcccctgaggtgatccgcaatgaacctgtg
tctgagaaggtcgacatctggtcctttggcgtggtgctatgggaactgctgactggtgag
atcccctacaaagacgtagattcctcagccattatctggggtgtgggaagcaacagtctc
catctgcccgtgccctccagttgcccagatggtttcaagatcctgcttcgccagtgctgg
aatagcaaaccacgaaatcgcccatcattccgacagatcctgctgcatctggacattgcc
tcagctgatgtactctccacaccccaggagacttactttaagtcccaggcagagtggcgg
gaagaagtaaaactgcactttgaaaagattaagtcagaagggacctgtctgcaccgccta
gaagaggaactggtgatgaggaggagggaggagctcagacacgccctggacatcagggag
cactatgaaaggaagctggagagagccaacaacctgtatatggaacttaatgccctcatg
ttgcagctggaactcaaggagagggagctgctcaggcgagagcaagctttagagcggagg
tgcccaggcctgctgaagccacacccttcccggggcctcctgcatggaaacacaatggag
aagcttatcaagaagaggaatgtgccacagaagctgtcaccccatagcaaaaggccagat
atcctcaagacggagtctttgctccctaaactagatgcagccctgagtggggtggggctt
cctgggtgtcctaagggccccccctcaccaggacggagtcgccgtggcaagacccgtcac
cgcaaggccagcgccaaggggagctgtggggacctgcctgggcttcgtacagctgtgcca
ccccatgaacctggaggaccaggaagcccagggggcctaggagggggaccctcagcctgg
gaggcctgccctcccgccctccgtgggcttcatcatgacctcctgctccgcaaaatgtct
tcatcgtccccagacctgctgtcagcagcactagggtcccggggccggggggccacaggc
ggagctggggatcctggctcaccacctccggcccggggtgacaccccaccaagtgagggc
tcagcccctggctccaccagcccagattcacctgggggagccaaaggggaaccacctcct
ccagtagggcctggtgaaggtgtggggcttctgggaactggaagggaagggacctcaggc
cggggaggaagccgggctgggtcccagcacttgaccccagctgcactgctgtacagggct
gccgtcacccgaagtcagaaacgtggcatctcatcggaagaggaggaaggagaggtagac
agtgaagtagagctgacatcaagccagaggtggcctcagagcctgaacatgcgccagtca
ctatctaccttcagctcagagaatccatcagatggggaggaaggcacagctagtgaacct
tcccccagtggcacacctgaagttggcagcaccaacactgatgagcggccagatgagcgg
tctgatgacatgtgctcccagggctcagaaatcccactggacccacctccttcagaggtc
atccctggccctgaacccagctccctgcccattccacaccaggaacttctcagagagcgg
ggccctcccaattctgaggactcagactgtgacagcactgaattggacaactccaacagc
gttgatgccttgcggcccccagcttccctccctccatga

All links

Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (13)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (5)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (14)   
   RefSeq(nuc) (2)   
   GenBank (6)   
   EMBL (6)   
Protein domain (4)   
   Pfam (4)   
All databases (38)   

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