KEGG   Homo sapiens (human): 7874Help
Entry
7874              CDS       T01001                                 

Gene name
USP7, HAUSP, TEF1
Definition
ubiquitin specific peptidase 7 (herpes virus-associated) (EC:3.4.19.12)
Orthology
K11838  
ubiquitin carboxyl-terminal hydrolase 7 [EC:3.1.2.15]
Organism
hsa  Homo sapiens (human)
Pathway
FoxO signaling pathway
Herpes simplex infection
Epstein-Barr virus infection
Viral carcinogenesis
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04068 FoxO signaling pathway
    7874 (USP7)
 Human Diseases
  Cancers
   05203 Viral carcinogenesis
    7874 (USP7)
  Infectious diseases
   05168 Herpes simplex infection
    7874 (USP7)
   05169 Epstein-Barr virus infection
    7874 (USP7)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.2  Thioester hydrolases
    3.1.2.15  ubiquitin thiolesterase
     7874 (USP7)
Peptidases [BR:hsa01002]
 Cysteine Peptidases
  Family C19: ubiquitin-specific protease family
   7874 (USP7)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Structure
PDB: 

Jmol
Position
16p13.3
AA seq 1086 aa AA seqDB search
MAGNHRLGLEAGDTDDPPRITQNPVINGNVALSDGHNTAEEDMEDDTSWRSEATFQFTVE
RFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQCNAESDSTSWSCHAQA
VLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPEKGFIDDDKVTFEVFVQ
ADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSV
PLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCV
EGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVGQLDGD
NKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEF
LQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEH
NYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRK
ERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNSSLAEFVQSLSQTMGFP
QDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTIFLETVDPELAASGATL
PKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYE
EVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSELPTAKEYFRDLYHRVDV
IFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQGYRDGPGNPLRHN
YEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLNSQFREEEITLYPDKHG
CVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLECLSPATSRTFRIEEIP
LDQVDIDKENEMLVTVAHFHKEVFGTFGIPFLLRIHQGEHFREVMKRIQSLLDIQEKEFE
KFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRSRYTYLEK
AIKIHN
NT seq 3261 nt NT seq  +upstreamnt  +downstreamnt
atggctgggaaccacaggcttgggctcgaagcgggagatacagatgacccaccaagaatt
actcagaaccctgtgatcaatgggaatgtggccctgagtgatggacacaacaccgcggag
gaggacatggaggatgacaccagttggcgctccgaggcaacctttcagttcactgtggag
cgcttcagcagactgagtgagtcggtccttagccctccgtgttttgtgcgaaatctgcca
tggaagattatggtgatgccacgcttttatccagacagaccacaccaaaaaagcgtagga
ttctttctccagtgcaatgctgaatctgattccacgtcatggtcttgccatgcacaagca
gtgctgaagataataaattacagagatgatgaaaagtcgttcagtcgtcgtattagtcat
ttgttcttccataaagaaaatgattggggattttccaattttatggcctggagtgaagtg
accgatcctgagaaaggatttatagatgatgacaaagttacctttgaagtctttgtacag
gcggatgctccccatggagttgcgtgggattcaaagaagcacacaggctacgtcggctta
aagaatcagggagcgacttgttacatgaacagcctgctacagacgttatttttcacgaat
cagctacgaaaggctgtgtacatgatgccaaccgagggggatgattcgtctaaaagcgtc
cctttagcattacaaagagtgttctatgaattacagcatagtgataaacctgtaggaaca
aaaaagttaacaaagtcatttgggtgggaaactttagatagcttcatgcaacatgatgtt
caggagctttgtcgagtgttgctcgataatgtggaaaataagatgaaaggcacctgtgta
gagggcaccatacccaaattattccgcggcaaaatggtgtcctatatccagtgtaaagaa
gtagactatcggtctgatagaagagaagattattatgatatccagctaagtatcaaagga
aagaaaaatatatttgaatcatttgtggattatgtggcagtaggacagctcgatggggac
aataaatacgacgctggggaacatggcttacaggaagcagagaaaggtgtgaaattccta
acattgccaccagtgttacatctacaactgatgagatttatgtatgaccctcagacggac
caaaatatcaagatcaatgataggtttgaattcccagagcagttaccacttgatgaattt
ttgcaaaaaacagatcctaaggaccctgcaaattatattcttcatgcagtcctggttcat
agtggagataatcatggtggacattatgtggtttatctaaaccccaaaggggatggcaaa
tggtgtaaatttgatgacgacgtggtgtcaaggtgtactaaagaggaagcaattgagcac
aattatgggggtcacgatgacgacctgtctgttcgacactgcactaatgcttacatgtta
gtctacatcagggaatcaaaactgagtgaagttttacaggcggtcaccgaccatgatatt
cctcagcagttggtggagcgattacaagaagagaaaaggatcgaggctcagaagcggaag
gagcggcaggaagcccatctctatatgcaagtgcagatagtcgcagaggaccagttttgt
ggccaccaagggaatgacatgtacgatgaagaaaaagtgaaatacactgtgttcaaagta
ttgaagaactcctcgcttgctgagtttgttcagagcctctctcagaccatgggatttcca
caagatcaaattcgattgtggcccatgcaagcaaggagtaatggaacaaaacgaccagca
atgttagataatgaagccgacggcaataaaacaatgattgagctcagtgataatgaaaac
ccttggacaatattcctggaaacagttgatcccgagctggctgctagtggagcgacctta
cccaagtttgataaagatcatgatgtaatgttatttttgaagatgtatgatcccaaaacg
cggagcttgaattactgtgggcatatctacacaccaatatcctgtaaaatacgtgacttg
ctcccagttatgtgtgacagagcaggatttattcaagatactagccttatcctctatgag
gaagttaaaccgaatttaacagagagaattcaggactatgacgtgtctcttgataaagcc
cttgatgaactaatggatggtgacatcatagtatttcagaaggatgaccctgaaaatgat
aacagtgaattacccaccgcaaaggagtatttccgagatctctaccaccgcgttgatgtc
attttctgtgataaaacaatccctaatgatcctggatttgtggttacgttatcaaataga
atgaattattttcaggttgcaaagacagttgcacagaggctcaacacagatccaatgttg
ctgcagtttttcaagtctcaaggttatagggatggcccaggtaatcctcttagacataat
tatgaaggtactttaagagatcttctacagttcttcaagcctagacaacctaagaaactt
tactatcagcagcttaagatgaaaatcacagactttgagaacaggcgaagttttaaatgt
atatggttaaacagccaatttagggaagaggaaataacactatatccagacaagcatggg
tgtgtccgggacctgttagaagaatgtaaaaaggccgtggagcttggggagaaagcatca
gggaaacttaggctgctagaaattgtaagctacaaaatcattggtgttcatcaagaagat
gaactattagaatgtttatctcctgcaacgagccggacgtttcgaatagaggaaatccct
ttggaccaggtggacatagacaaagagaatgagatgcttgtcacagtggcgcatttccac
aaagaggtcttcggaacgttcggaatcccgtttttgctgaggatacaccagggcgagcat
tttcgagaagtgatgaagcgaatccagagcctgctggacatccaggagaaggagtttgag
aagtttaaatttgcaattgtaatgatgggccgacaccagtacataaatgaagacgagtat
gaagtaaatttgaaagactttgagccacagcccggtaatatgtctcatcctcggccttgg
ctagggctcgaccacttcaacaaagccccaaagaggagtcgctacacttaccttgaaaag
gccattaaaatccataactga

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