| Entry |
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| Gene name |
DHX58, D11LGP2, D11lgp2e, LGP2, RLR-3
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| Definition |
DEXH (Asp-Glu-X-His) box polypeptide 58 (EC:3.6.4.13)
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| Orthology |
| ATP-dependent RNA helicase DHX58 [EC: 3.6.3.14] |
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| Organism |
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| Pathway |
| RIG-I-like receptor signaling pathway |
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| Class |
Organismal Systems; Immune system; RIG-I-like receptor signaling pathway [PATH: hsa04622]
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| SSDB |
   |
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| Motif |
 |
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| Other DBs |
NCBI-GI: NCBI-GeneID: OMIM: HGNC: HPRD: Ensembl: Vega: UniProt: |
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| Structure |
PDB: |
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| Position |
17q21.2
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| AA seq |
678 aa  
MELRSYQWEVIMPALEGKNIIIWLPTGAGKTRAAAYVAKRHLETVDGAKVVVLVNRVHLV
TQHGEEFRRMLDGRWTVTTLSGDMGPRAGFGHLARCHDLLICTAELLQMALTSPEEEEHV
ELTVFSLIVVDECHHTHKDTVYNVIMSQYLELKLQRAQPLPQVLGLTASPGTGGASKLDG
AINHVLQLCANLDTWCIMSPQNCCPQLQEHSQQPCKQYNLCHRRSQDPFGDLLKKLMDQI
HDHLEMPELSRKFGTQMYEQQVVKLSEAAALAGLQEQRVYALHLRRYNDALLIHDTVRAV
DALAALQDFYHREHVTKTQILCAERRLLALFDDRKNELAHLATHGPENPKLEMLEKILQR
QFSSSNSPRGIIFTRTRQSAHSLLLWLQQQQGLQTVDIRAQLLIGAGNSSQSTHMTQRDQ
QEVIQKFQDGTLNLLVATSVAEEGLDIPHCNVVVRYGLLTNEISMVQARGRARADQSVYA
FVATEGSRELKRELINEALETLMEQAVAAVQKMDQAEYQAKIRDLQQAALTKRAAQAAQR
ENQRQQFPVEHVQLLCINCMVAVGHGSDLRKVEGTHHVNVNPNFSNYYNVSRDPVVINKV
FKDWKPGGVISCRNCGEVWGLQMIYKSVKLPVLKVRSMLLETPQGRIQAKKWSRVPFSVP
DFDFLQHCAENLSDLSLD |
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| NT seq |
2037 nt  +upstreamnt +downstreamnt
atggagcttcggtcctaccaatgggaggtgatcatgcctgccctggagggcaagaatatc
atcatctggctgcccacgggtgccgggaagacccgggcggctgcttatgtggccaagcgg
cacctagagactgtggatggagccaaggtggttgtattggtcaacagggtgcacctggtg
acccagcatggtgaagagttcaggcgcatgctggatggacgctggaccgtgacaaccctg
agtggggacatgggaccacgtgctggctttggccacctggcccggtgccatgacctgctc
atctgcacagcagagcttctgcagatggcactgaccagccccgaggaggaggagcacgtg
gagctcactgtcttctccctgatcgtggtggatgagtgccaccacacgcacaaggacacc
gtctacaacgtcatcatgagccagtacctagaacttaaactccagagggcacagccgcta
ccccaggtgctgggtctcacagcctccccaggcactggcggggcctccaaactcgatggg
gccatcaaccacgtcctgcagctctgtgccaacttggacacgtggtgcatcatgtcaccc
cagaactgctgcccccagctgcaggagcacagccaacagccttgcaaacagtacaacctc
tgccacaggcgcagccaggatccgtttggggacttgctgaagaagctcatggaccaaatc
catgaccacctggagatgcctgagttgagccggaaatttgggacgcaaatgtatgagcag
caggtggtgaagctgagtgaggctgcggctttggctgggcttcaggagcaacgggtgtat
gcgcttcacctgaggcgctacaatgacgcgctgctcatccatgacaccgtccgcgccgtg
gatgccttggctgcgctgcaggatttctatcacagggagcacgtcactaaaacccagatc
ctgtgtgccgagcgccggctgctggccctgttcgatgaccgcaagaatgagctggcccac
ttggcaactcatggcccagagaatccaaaactggagatgctggaaaagatcctgcaaagg
cagttcagtagctctaacagccctcggggtatcatcttcacccgcacccgccaaagcgca
cactccctcctgctctggctccagcagcagcagggcctgcagactgtggacatccgggcc
cagctactgattggggctgggaacagcagccagagcacccacatgacccagagggaccag
caagaagtgatccagaagttccaagatggaaccctgaaccttctggtggccacgagtgtg
gcggaggaggggctggacatcccacattgcaatgtggtggtgcgttatgggctcttgacc
aatgaaatctccatggtccaggccaggggccgtgcccgggccgatcagagtgtatacgcg
tttgtagcaactgaaggtagccgggagctgaagcgggagctgatcaacgaggcgctggag
acgctgatggagcaggcagtggctgctgtgcagaaaatggaccaggccgagtaccaggcc
aagatccgggatctgcagcaggcagccttgaccaagcgggcggcccaggcagcccagcgg
gagaaccagcggcagcagttcccagtggagcacgtgcagctactctgcatcaactgcatg
gtggctgtgggccatggcagcgacctgcggaaggtggagggcacccaccatgtcaatgtg
aaccccaacttctcgaactactataatgtctccagggatcctgtggtcatcaacaaagtc
ttcaaggactggaagcctgggggtgtcatcagctgcaggaactgtggggaggtctggggt
ctgcagatgatctacaagtcagtgaagctgccagtgctcaaagtccgcagcatgctgctg
gagacccctcaggggcggatccaggccaaaaagtggtcccgcgtgcccttctccgtgcct
gactttgacttcctgcagcattgtgccgagaacttgtcggacctctccctggactga |
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