| Entry |
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| Gene name |
ALDH5A1, SSADH, SSDH
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| Definition |
aldehyde dehydrogenase 5 family, member A1 (EC:1.2.1.24)
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| Orthology |
| succinate-semialdehyde dehydrogenase [EC: 1.2.1.24] |
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| Organism |
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| Pathway |
| Alanine, aspartate and glutamate metabolism | | Butanoate metabolism | | Metabolic pathways |
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| Module |
| GABA (gamma-Aminobutyrate) shunt |
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| Disease |
| Succinic semialdehyde dehydrogenase (SSADH) deficiency |
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| Class |
Metabolism; Carbohydrate metabolism; Butanoate metabolism [PATH: hsa00650]
Metabolism; Amino acid metabolism; Alanine, aspartate and glutamate metabolism [PATH: hsa00250]
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| SSDB |
   |
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| Motif |
 |
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| Other DBs |
NCBI-GI: NCBI-GeneID: OMIM: HGNC: HPRD: Ensembl: Vega: UniProt: |
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| Structure |
PDB: |
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| Position |
6p22
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| AA seq |
535 aa  
MATCIWLRSCGARRLGSTFPGCRLRPRAGGLVPASGPAPGPAQLRCYAGRLAGLSAALLR
TDSFVGGRWLPAAATFPVQDPASGAALGMVADCGVREARAAVRAAYEAFCRWREVSAKER
SSLLRKWYNLMIQNKDDLARIITAESGKPLKEAHGEILYSAFFLEWFSEEARRVYGDIIH
TPAKDRRALVLKQPIGVAAVITPWNFPSAMITRKVGAALAAGCTVVVKPAEDTPFSALAL
AELASQAGIPSGVYNVIPCSRKNAKEVGEAICTDPLVSKISFTGSTTTGKILLHHAANSV
KRVSMELGGLAPFIVFDSANVDQAVAGAMASKFRNTGQTCVCSNQFLVQRGIHDAFVKAF
AEAMKKNLRVGNGFEEGTTQGPLINEKAVEKVEKQVNDAVSKGATVVTGGKRHQLGKNFF
EPTLLCNVTQDMLCTHEETFGPLAPVIKFDTEEEAIAIANAADVGLAGYFYSQDPAQIWR
VAEQLEVGMVGVNEGLISSVECPFGGVKQSGLGREGSKYGIDEYLELKYVCYGGL |
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| NT seq |
1608 nt  +upstreamnt +downstreamnt
atggcgacctgcatttggctgcggagctgtggggcccggcgcctcgggtcgacgtttcca
ggctgccgcctccgcccccgcgccggcggcctggtccctgcctccgggcctgcgcccggc
ccggcccagctccgctgctacgctgggcgcctggcgggcctctctgcggcgctgctgcgc
accgacagcttcgtgggcggccgctggctcccggccgccgccaccttccccgtgcaagac
ccggccagcggcgccgctctgggcatggtagccgactgcggggtgcgagaggcccgcgcc
gccgtgcgcgctgcctacgaggctttctgccgctggagggaggtctccgccaaggagagg
agttcattacttcggaagtggtacaatttaatgatacaaaataaggatgaccttgccaga
ataatcacagctgaaagtggaaagccactgaaggaggcacatggagaaattctctattcc
gcctttttcctagagtggttctctgaggaagcccgccgtgtttacggagacattatccac
accccggcaaaggacaggcgggccctggtcctcaagcagcccataggcgtggctgcagtc
atcaccccgtggaatttccccagtgccatgatcacccggaaggtgggggccgccctggca
gccggctgtactgtcgtggtgaagcctgccgaagacacgcccttctccgccctggccctg
gctgagcttgcaagccaggctgggattccttcaggtgtatacaatgttattccctgttct
cgaaagaatgccaaggaagtaggggaggcaatttgtactgatcctctggtgtccaaaatt
tcctttactggttcaacaactacaggaaagatcctgttgcaccacgcagcaaactctgtg
aaaagggtctctatggagctgggcggccttgctccatttatagtatttgacagtgccaac
gtggaccaggctgtagcaggggccatggcatctaaatttaggaacactggacagacttgt
gtttgctcaaaccaattcttggtgcaaaggggcatccatgatgcctttgtaaaagcattc
gccgaggccatgaagaagaacctgcgcgtaggtaatggatttgaggaaggaactactcag
ggcccattaattaatgaaaaagcggtagaaaaggtggagaaacaggtgaatgatgccgtt
tctaaaggtgccaccgttgtgacaggtggaaaacgacaccaacttggaaaaaatttcttt
gagcctaccctgctgtgcaatgtcacccaggacatgctgtgcactcatgaagagactttc
gggcctctggcaccagttatcaagttcgatacagaggaggaggctatagcaatcgctaac
gcagctgatgttgggttagcaggttatttttactctcaagacccagcccagatctggaga
gtggcagagcagctggaagtgggcatggttggcgtcaacgaaggattaatttcctctgtg
gagtgcccttttggtggagtgaagcagtccggccttgggcgagaggggtccaagtatggc
attgatgagtatctggaactcaagtatgtgtgttacgggggcttgtag |
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