KEGG   Homo sapiens (human): 80201Help
Entry
80201             CDS       T01001                                 

Gene name
HKDC1
Definition
hexokinase domain containing 1 (EC:2.7.1.1)
Orthology
K00844  
hexokinase [EC:2.7.1.1]
Organism
hsa  Homo sapiens (human)
Pathway
Glycolysis / Gluconeogenesis
Fructose and mannose metabolism
Galactose metabolism
Starch and sucrose metabolism
Amino sugar and nucleotide sugar metabolism
Butirosin and neomycin biosynthesis
Metabolic pathways
Carbon metabolism
HIF-1 signaling pathway
Insulin signaling pathway
Type II diabetes mellitus
Carbohydrate digestion and absorption
Module
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
Nucleotide sugar biosynthesis, glucose => UDP-glucose
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Metabolism
  Overview
   01200 Carbon metabolism
    80201 (HKDC1)
  Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    80201 (HKDC1)
   00051 Fructose and mannose metabolism
    80201 (HKDC1)
   00052 Galactose metabolism
    80201 (HKDC1)
   00500 Starch and sucrose metabolism
    80201 (HKDC1)
   00520 Amino sugar and nucleotide sugar metabolism
    80201 (HKDC1)
  Biosynthesis of other secondary metabolites
   00524 Butirosin and neomycin biosynthesis
    80201 (HKDC1)
 Environmental Information Processing
  Signal transduction
   04066 HIF-1 signaling pathway
    80201 (HKDC1)
 Organismal Systems
  Endocrine system
   04910 Insulin signaling pathway
    80201 (HKDC1)
  Digestive system
   04973 Carbohydrate digestion and absorption
    80201 (HKDC1)
 Human Diseases
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    80201 (HKDC1)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.1  hexokinase
     80201 (HKDC1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Position
10q22.1
AA seq 917 aa AA seqDB search
MFAVHLMAFYFSKLKEDQIKKVDRFLYHMRLSDDTLLDIMRRFRAEMEKGLAKDTNPTAA
VKMLPTFVRAIPDGSENGEFLSLDLGGSKFRVLKVQVAEEGKRHVQMESQFYPTPNEIIR
GNGTELFEYVADCLADFMKTKDLKHKKLPLGLTFSFPCRQTKLEEGVLLSWTKKFKARGV
QDTDVVSRLTKAMRRHKDMDVDILALVNDTVGTMMTCAYDDPYCEVGVIIGTGTNACYME
DMSNIDLVEGDEGRMCINTEWGAFGDDGALEDIRTEFDRELDLGSLNPGKQLFEKMISGL
YLGELVRLILLKMAKAGLLFGGEKSSALHTKGKIETRHVAAMEKYKEGLANTREILVDLG
LEPSEADCIAVQHVCTIVSFRSANLCAAALAAILTRLRENKKVERLRTTVGMDGTLYKIH
PQYPKRLHKVVRKLVPSCDVRFLLSESGSTKGAAMVTAVASRVQAQRKQIDRVLALFQLT
REQLVDVQAKMRAELEYGLKKKSHGLATVRMLPTYVCGLPDGTEKGKFLALDLGGTNFRV
LLVKIRSGRRSVRMYNKIFAIPLEIMQGTGEELFDHIVQCIADFLDYMGLKGASLPLGFT
FSFPCRQMSIDKGTLIGWTKGFKATDCEGEDVVDMLREAIKRRNEFDLDIVAVVNDTVGT
MMTCGYEDPNCEIGLIAGTGSNMCYMEDMRNIEMVEGGEGKMCINTEWGGFGDNGCIDDI
RTRYDTEVDEGSLNPGKQRYEKMTSGMYLGEIVRQILIDLTKQGLLFRGQISERLRTRGI
FETKFLSQIESDRLALLQVRRILQQLGLDSTCEDSIVVKEVCGAVSRRAAQLCGAGLAAI
VEKRREDQGLEHLRITVGVDGTLYKLHPHFSRILQETVKELAPRCDVTFMLSEDGSGKGA
ALITAVAKRLQQAQKEN
NT seq 2754 nt NT seq  +upstreamnt  +downstreamnt
atgtttgcggtccacttgatggcattttacttcagcaagctgaaggaggaccagatcaag
aaggtggacaggttcctgtatcacatgcggctctccgatgacacccttttggacatcatg
aggcggttccgggctgagatggagaagggcctggcaaaggacaccaaccccacggctgca
gtgaagatgttgcccaccttcgtcagggccattcccgatggttccgaaaatggggagttc
ctttccctggatctcggagggtccaagttccgagtgctgaaggtgcaagtcgctgaagag
gggaagcgacacgtgcagatggagagtcagttctacccaacgcccaatgaaatcatccgc
gggaacggcacagagctgtttgaatatgtagctgactgtctggcagatttcatgaagacc
aaagatttaaagcataagaaattgccccttggcctaactttttctttcccctgtcgacag
actaaactggaagagggtgtcctactttcgtggacaaaaaagtttaaggcacgaggagtt
caggacacggatgtggtgagccgtctgaccaaagccatgagaagacacaaggacatggac
gtggacatcctggccctggtcaatgacaccgtggggaccatgatgacctgtgcctatgac
gacccctactgcgaagttggtgtcatcatcggaactggcaccaatgcgtgttacatggag
gacatgagcaacattgacctggtggagggcgacgagggcaggatgtgcatcaacacagag
tggggggccttcggggacgacggggccctggaggacattcgcactgagttcgacagggag
ctggacctcggctctctcaacccaggaaagcaactgttcgagaagatgatcagtggcctg
tacctgggggagcttgtcaggcttatcttgctgaagatggccaaggctggcctcctgttt
ggtggtgagaaatcttctgctctccacactaagggcaagatcgaaacacggcacgtggct
gccatggagaagtataaagaaggccttgctaatacaagagagatcctggtggacctgggt
ctggaaccgtctgaggctgactgcattgccgtccagcatgtctgtaccatcgtctccttc
cgctcggccaatctctgtgcagcagctctggcggccatcctgacacgcctccgggagaac
aagaaggtggaacggctccggaccacagtgggcatggacggcaccctctacaagatacac
cctcagtacccaaaacgcctgcacaaggtggtgaggaaactggtcccaagctgtgatgtc
cgcttcctcctgtcagagagtggcagcaccaagggggccgccatggtgaccgcggtggcc
tcccgcgtgcaggcccagcggaagcagatcgacagggtgctggctttgttccagctgacc
cgagagcagctcgtggacgtgcaggccaagatgcgggctgagctggagtatgggctgaag
aagaagagccacgggctggccacggtcaggatgctgcccacctacgtctgcgggctgccg
gacggcacagagaaaggaaagtttctcgccctggatcttgggggaaccaacttccgggtc
ctcctggtgaagatcagaagtggacggaggtcagtgcgaatgtacaacaagatcttcgcc
atccccctggagatcatgcagggcactggtgaggagctctttgatcacattgtgcagtgc
atcgccgacttcctggactacatgggcctcaagggagcctccctacctttgggcttcaca
ttctcatttccctgcaggcagatgagcattgacaagggaacactcatagggtggaccaaa
ggtttcaaggccactgactgtgaaggggaggacgtggtggacatgctcagggaagccatc
aagaggagaaacgagtttgacctggacattgttgcagtcgtgaatgatacagtggggacc
atgatgacctgtggctatgaagatcctaattgtgagattggcctgattgcaggaacaggc
agcaacatgtgctacatggaggacatgaggaacatcgagatggtggaggggggtgaaggg
aagatgtgcatcaatacagagtggggaggatttggagacaatggctgcatagatgacatc
cggacccgatacgacacggaggtggatgaggggtccttgaatcctggcaagcagagatac
gagaaaatgaccagtgggatgtacttgggggagattgtgcggcagatcctgatcgacctg
accaagcagggtctcctcttccgagggcagatttcagagcgtctccggaccaggggcatc
ttcgaaaccaagttcctgtcccagatcgaaagcgatcggctggcccttctccaggtcagg
aggattctgcagcagctgggcctggacagcacgtgtgaggacagcatcgtggtgaaggag
gtgtgcggagccgtgtcccggcgggcggcccagctctgcggtgctggcctggccgctata
gtggaaaaaaggagagaagaccaggggctagagcacctgaggatcactgtgggtgtggac
ggcaccctgtacaagctgcaccctcacttttctagaatattgcaggaaactgtgaaggaa
ctagcccctcgatgtgatgtgacattcatgctgtcagaagatggcagtggaaaaggggca
gcactgatcactgctgtggccaagaggttacagcaggcacagaaggagaactag

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