KEGG   Homo sapiens (human): 81704Help
Entry
81704             CDS       T01001                                 

Gene name
DOCK8, HEL-205, MRD2, ZIR8
Definition
(RefSeq) dedicator of cytokinesis 8
Organism
hsa  Homo sapiens (human)
Disease
H00773  
Autosomal dominant mental retardation
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-ProteinID: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Position
9p24.3
AA seq 2099 aa AA seqDB search
MATLPSAERRAFALKINRYSSAEIRKQFTLPPNLGQYHRQSISTSGFPSLQLPQFYDPVE
PVDFEGLLMTHLNSLDVQLAQELGDFTDDDLDVVFTPKECRTLQPSLPEEGVELDPHVRD
CVQTYIREWLIVNRKNQGSPEICGFKKTGSRKDFHKTLPKQTFESETLECSEPAAQAGPR
HLNVLCDVSGKGPVTACDFDLRSLQPDKRLENLLQQVSAEDFEKQNEEARRTNRQAELFA
LYPSVDEEDAVEIRPVPECPKEHLGNRILVKLLTLKFEIEIEPLFASIALYDVKERKKIS
ENFHCDLNSDQFKGFLRAHTPSVAASSQARSAVFSVTYPSSDIYLVVKIEKVLQQGEIGD
CAEPYTVIKESDGGKSKEKIEKLKLQAESFCQRLGKYRMPFAWAPISLSSFFNVSTLERE
VTDVDSVVGRSSVGERRTLAQSRRLSERALSLEENGVGSNFKTSTLSVSSFFKQEGDRLS
DEDLFKFLADYKRSSSLQRRVKSIPGLLRLEISTAPEIINCCLTPEMLPVKPFPENRTRP
HKEILEFPTREVYVPHTVYRNLLYVYPQRLNFVNKLASARNITIKIQFMCGEDASNAMPV
IFGKSSGPEFLQEVYTAVTYHNKSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQQKQGA
SVETLLGYSWLPILLNERLQTGSYCLPVALEKLPPNYSMHSAEKVPLQNPPIKWAEGHKG
VFNIEVQAVSSVHTQDNHLEKFFTLCHSLESQVTFPIRVLDQKISEMALEHELKLSIICL
NSSRLEPLVLFLHLVLDKLFQLSVQPMVIAGQTANFSQFAFESVVAIANSLHNSKDLSKD
QHGRNCLLASYVHYVFRLPEVQRDVPKSGAPTALLDPRSYHTYGRTSAAAVSSKLLQARV
MSSSNPDLAGTHSAADEEVKNIMSSKIADRNCSRMSYYCSGSSDAPSSPAAPRPASKKHF
HEELALQMVVSTGMVRETVFKYAWFFFELLVKSMAQHVHNMDKRDSFRRTRFSDRFMDDI
TTIVNVVTSEIAALLVKPQKENEQAEKMNISLAFFLYDLLSLMDRGFVFNLIRHYCSQLS
AKLSNLPTLISMRLEFLRILCSHEHYLNLNLFFMNADTAPTSPCPSISSQNSSSCSSFQD
QKIASMFDLTSEYRQQHFLTGLLFTELAAALDAEGEGISKVQRKAVSAIHSLLSSHDLDP
RCVKPEVKVKIAALYLPLVGIILDALPQLCDFTVADTRRYRTSGSDEEQEGAGAINQNVA
LAIAGNNFNLKTSGIVLSSLPYKQYNMLNADTTRNLMICFLWIMKNADQSLIRKWIADLP
STQLNRILDLLFICVLCFEYKGKQSSDKVSTQVLQKSRDVKARLEEALLRGEGARGEMMR
RRAPGNDRFPGLNENLRWKKEQTHWRQANEKLDKTKAELDQEALISGNLATEAHLIILDM
QENIIQASSALDCKDSLLGGVLRVLVNSLNCDQSTTYLTHCFATLRALIAKFGDLLFEEE
VEQCFDLCHQVLHHCSSSMDVTRSQACATLYLLMRFSFGATSNFARVKMQVTMSLASLVG
RAPDFNEEHLRRSLRTILAYSEEDTAMQMTPFPTQVEELLCNLNSILYDTVKMREFQEDP
EMLMDLMYRIAKSYQASPDLRLTWLQNMAEKHTKKKCYTEAAMCLVHAAALVAEYLSMLE
DHSYLPVGSVSFQNISSNVLEESVVSEDTLSPDEDGVCAGQYFTESGLVGLLEQAAELFS
TGGLYETVNEVYKLVIPILEAHREFRKLTLTHSKLQRAFDSIVNKDHKRMFGTYFRVGFF
GSKFGDLDEQEFVYKEPAITKLPEISHRLEAFYGQCFGAEFVEVIKDSTPVDKTKLDPNK
AYIQITFVEPYFDEYEMKDRVTYFEKNFNLRRFMYTTPFTLEGRPRGELHEQYRRNTVLT
TMHAFPYIKTRISVIQKEEFVLTPIEVAIEDMKKKTLQLAVAINQEPPDAKMLQMVLQGS
VGATVNQGPLEVAQVFLAEIPADPKLYRHHNKLRLCFKEFIMRCGEAVEKNKRLITADQR
EYQQELKKNYNKLKENLRPMIERKIPELYKPIFRVESQKRDSFHRSSFRKCETQLSQGS
NT seq 6300 nt NT seq  +upstreamnt  +downstreamnt
atggccactctgccgagcgcagagcgccgcgcgttcgcgctcaagatcaacaggtattct
tcagcggaaataaggaaacagtttactctcccaccaaaccttggccagtaccatcgacag
agcataagtacctctggcttcccctctcttcaactacctcagttttatgaccctgtggag
ccagtggactttgaaggacttctgatgacacacctgaacagcctggatgtgcagcttgcc
caggagctcggggacttcactgatgacgacttggacgtggtgttcacgccaaaggaatgt
aggactttgcagccctctttgccggaggaaggggttgaactggaccctcatgtcagggac
tgtgttcagacctacatccgtgagtggctaatcgtgaaccggaaaaaccaaggaagtcca
gaaatctgtggctttaaaaagactggatctcgaaaagattttcacaagacgcttccgaaa
cagacgtttgagtcggaaaccttggagtgcagtgaacccgctgctcaggcaggcccccgc
cacttaaacgtgctgtgcgacgtgtctgggaaaggccccgtcactgcctgtgactttgac
ctccgcagcctgcagcctgacaagcggctagaaaacctcctgcagcaagtgagtgccgag
gactttgagaagcagaacgaggaggcccggaggaccaataggcaggccgagctctttgcc
ctttacccatcagtggacgaggaggatgctgtggaaatacgtccagtaccagaatgtccc
aaggaacacctgggcaacagaatattggtcaagttgctgaccttgaagttcgagattgaa
attgagcccctgtttgccagcattgccctctacgatgttaaagaaaggaaaaagatctca
gaaaattttcactgtgacctgaactctgaccagttcaaaggatttctgcgagctcacacg
ccttcagtggccgcatcaagtcaggcgagatctgcagtcttctcagtcacctacccgtcc
tcagacatctacctggtagtcaagattgaaaaagtcctgcagcagggagagattggagac
tgtgcagagccctacacggttatcaaagaaagtgatggtggaaagagtaaagaaaagatt
gaaaaactaaaactccaagctgaatccttctgccagcgtttggggaaataccggatgccc
tttgcctgggcacccataagcttatcaagcttcttcaatgtctccacccttgagagggag
gtaactgatgtggactctgtggttgggagaagctcagtgggtgaacggaggacattggcc
caatctagaaggctttctgaaagagccctctccttggaggaaaatggggttggatccaac
ttcaaaacctccactctgagcgttagcagctttttcaagcaggaaggagatcgccttagc
gatgaagacttattcaagtttttagctgactacaaaagatcatcatccttacagagacga
gtcaagtcaattccaggcttgctaagactggagatttctacagctccagagatcatcaat
tgctgtctgactcctgaaatgctgcccgtgaaaccctttcctgaaaaccggacacgcccg
cacaaagagattttggaatttccaacacgagaagtatatgtccctcacactgtgtacaga
aaccttctctatgtctacccacagaggctgaactttgtaaacaaactagcatcagcccgg
aacattacaataaagatccagtttatgtgtggagaagatgctagcaatgcgatgccggtc
atctttggaaaatccagcgggcctgaatttctgcaggaagtgtacacagctgttacatac
cataataagtctcctgacttttatgaagaagtgaaaattaagctccccgctaagctcaca
gtaaatcaccacctcctgttcaccttctaccatatcagctgtcagcagaagcaaggagcc
tccgtggaaactctcctgggatattcatggctgccaattctcttaaatgaacgtcttcaa
actggatcctactgtctcccagttgccttggaaaaattgccacccaactactccatgcat
tctgctgagaaagtcccattacagaatcctcccattaagtgggctgaaggacataaggga
gtatttaatattgaagtgcaagctgtttcttctgtacacacccaggacaaccacctggag
aagttcttcaccctctgccactccctggagagccaggtgaccttccccatccgcgtgctg
gatcagaaaatcagcgagatggcgctggagcatgagctgaagctcagcatcatctgcctg
aactcctcccgcctggagccgctcgtgctcttcctgcacctggtgctggacaagctcttc
cagctgtccgtgcagcccatggtcatcgctggccagacagccaacttctcccagtttgcc
ttcgagtccgtggtggccatcgccaacagtctgcacaacagcaaggacctgagcaaggac
cagcatgggaggaactgcctgctggcttcctacgtgcactacgtcttccgcctgccagag
gtgcaaagggatgtgcccaagtcaggcgctcccactgccctcctagaccctcggagctac
cacacgtatggccgcacatcagctgctgctgtgagttcaaagctgctgcaggcccgggtg
atgagcagcagtaacccagacctcgcggggacacactccgcagcagacgaggaagtgaag
aacatcatgtcttcaaagatcgccgatcgcaactgcagccgaatgtcttactattgctct
ggcagtagtgatgctccaagttcacctgcagccccaaggccagccagcaaaaagcatttc
catgaggagcttgcccttcagatggtggtcagcaccggaatggtgagagaaacagtcttc
aagtatgcctggttcttctttgagcttctggtgaaaagcatggcccagcacgtacataac
atggacaaacgggacagttttcggaggactcgtttttctgaccgtttcatggatgacata
actactattgttaatgtggtcacctcggaaattgcagcccttttagtaaaaccacagaag
gaaaatgaacaggcggaaaagatgaacatcagcctggctttcttcttgtatgaccttctc
tccctcatggatcggggctttgtgtttaacctcatcagacattattgcagccagctgtca
gccaagctcagtaaccttccaacgctcatttccatgaggctagagttcctgagaatcctc
tgtagccatgagcattacctcaatctgaaccttttttttatgaatgctgatactgctcca
acatctccttgtccttccatatcttcccagaactcaagctcctgctccagcttccaggac
cagaagatcgccagcatgttcgatctgacttccgagtaccgccagcagcacttcctcacc
gggctcctcttcacagaactggctgctgccctggatgccgaaggggaaggaatcagcaaa
gtacaaaggaaagctgtcagtgcaattcacagcctgctaagttctcacgacctggaccca
cgctgtgtcaaaccagaggtgaaggtcaaaatcgccgccctttacctacctttagttggc
atcattttggatgctttgccacagctctgtgactttacagttgcagatactcgcagatac
cgcaccagtggctcggatgaagaacaagaaggagccggtgccattaaccagaatgtggct
ctggccatagcagggaataatttcaatttgaaaacaagtggaatagtgctgtcttccttg
ccctataagcagtacaacatgctgaacgcggacactactcgcaacctcatgatctgcttc
ctctggatcatgaaaaatgctgatcagagcctcattaggaagtggattgctgacctgcca
tcaacgcagctcaacaggattttagatctacttttcatctgtgtgttatgttttgagtat
aagggaaaacagagttctgacaaagtcagtacccaagtcctgcagaagtcaagggatgtc
aaggcccggctggaagaggctttgctccgtggggaaggggccagaggggagatgatgcgc
cgccgggctccagggaacgaccgatttccaggcctaaatgaaaatttgagatggaagaaa
gagcagacacattggcggcaagctaatgagaagctagataaaacaaaggccgagttagat
caagaagccttgatcagtggcaatctggctacagaagcacatttaatcatcctggatatg
caggaaaacattatccaggcgagctcggctctggactgtaaagacagcctgctgggaggt
gttctgagggtgctggtgaattctctgaactgtgatcagagtaccacctacctgactcac
tgctttgcaacactccgtgctctcatcgccaagtttggagacttactcttcgaagaggag
gtggaacagtgtttcgacctatgtcaccaagtcctgcaccactgcagcagcagcatggat
gtcacccggagccaagcctgtgccaccctttacctcctcatgaggttcagttttggagcc
accagtaattttgcaagagtaaagatgcaagtaaccatgtccctggcatctttggtggga
agagcaccagactttaatgaagagcacctgagaagatccttgaggacaattttggcctat
tcagaagaggacacagccatgcagatgactccttttcccacccaggtggaggaacttctc
tgtaatctgaatagcatcttatatgacacagtgaaaatgagggaatttcaggaagatcct
gagatgcttatggatctcatgtacagaattgccaagagttaccaggcatctcctgatctg
cggctgacctggctccagaacatggcagagaaacacaccaagaagaagtgctacacggag
gctgccatgtgcctggtgcacgccgctgcgttagtggctgagtatctgagcatgctggag
gaccacagctacctgcccgtgggcagtgtcagcttccagaatatttcttccaatgtgctg
gaggagtctgtggtctctgaggacaccctgtcacctgacgaggatggggtgtgcgcaggc
cagtacttcaccgagagtggcctggtaggcctcctggagcaggccgcggagctcttcagc
acgggaggcttatatgagacagttaatgaggtctacaagctggtcatccccatcctagaa
gcgcatcgagaattccggaagctgacactcactcacagcaagctgcagagagccttcgac
agcatcgttaacaaggatcataagagaatgtttggaacctacttccgagttggtttcttt
ggatccaaatttggggatttggatgaacaggagtttgtctacaaagagcctgcaattacc
aagcttcctgagatctcacatagactagaggcattttatggtcaatgttttggtgcagaa
tttgtggaagtgattaaagactccactcctgtggacaaaaccaagttggatcctaacaag
gcctacatacagatcacttttgtggagccctactttgatgagtatgagatgaaagacagg
gtcacatactttgagaagaatttcaacctccggaggttcatgtacaccaccccgttcacc
ctggaggggcggcctcggggagagctgcatgagcagtacagaaggaacacagtcctgacc
actatgcacgccttcccctacatcaagaccaggatcagcgtcatccagaaggaggagttt
gttttgacaccgattgaagttgccattgaagacatgaagaagaagaccctgcagttagca
gttgccattaaccaggagccgcctgatgcaaagatgcttcagatggtgctgcaaggctct
gtgggagctactgtaaatcagggaccactggaagtagcccaagtgtttttggctgaaatt
cctgctgatccaaaactctatcgacatcacaacaagttgaggttatgctttaaggaattc
atcatgagatgtggtgaagctgtagagaaaaacaagcgtctcatcacggcagaccagagg
gaatatcagcaggaactcaaaaagaactataacaagctaaaagagaacctcaggccaatg
atcgagcggaaaattccagaactgtacaagccaatattcagagttgagagtcaaaagagg
gactccttccacagatctagtttcaggaaatgtgaaacccagttgtcacagggcagctaa

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