KEGG T01001: 8321

Homo sapiens (human): 8321

Entry

8321 CDS T01001

Gene name

FZD1

Definition

(RefSeq) frizzled class receptor 1

K02432

frizzled 1/7

Organism

hsa Homo sapiens (human)

Pathway

hsa04150	mTOR signaling pathway
hsa04310	Wnt signaling pathway
hsa04390	Hippo signaling pathway
hsa04550	Signaling pathways regulating pluripotency of stem cells
hsa04916	Melanogenesis
hsa04934	Cushing's syndrome
hsa05165	Human papillomavirus infection
hsa05166	HTLV-I infection
hsa05200	Pathways in cancer
hsa05205	Proteoglycans in cancer
hsa05217	Basal cell carcinoma
hsa05224	Breast cancer
hsa05225	Hepatocellular carcinoma
hsa05226	Gastric cancer

Module

hsa_M00677

Wnt signaling

Network

N00056	Wnt signaling pathway
N00060	LRP6-overexpression to Wnt signaling pathway

Brite

KEGG Orthology (KO) [BR:hsa00001]
Environmental Information Processing
  Signal transduction
   04310 Wnt signaling pathway
    8321 (FZD1)
   04390 Hippo signaling pathway
    8321 (FZD1)
   04150 mTOR signaling pathway
    8321 (FZD1)
Cellular Processes
  Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    8321 (FZD1)
Organismal Systems
  Endocrine system
   04916 Melanogenesis
    8321 (FZD1)
Human Diseases
  Cancers
   05200 Pathways in cancer
    8321 (FZD1)
   05205 Proteoglycans in cancer
    8321 (FZD1)
   05225 Hepatocellular carcinoma
    8321 (FZD1)
   05226 Gastric cancer
    8321 (FZD1)
   05217 Basal cell carcinoma
    8321 (FZD1)
   05224 Breast cancer
    8321 (FZD1)
  Endocrine and metabolic diseases
   04934 Cushing's syndrome
    8321 (FZD1)
  Infectious diseases
   05166 HTLV-I infection
    8321 (FZD1)
   05165 Human papillomavirus infection
    8321 (FZD1)
G protein-coupled receptors [BR:hsa04030]
Others
  Wnt signaling
   Frizzled / Smoothened family
    8321 (FZD1)

SSDB

Motif

Pfam:

Frizzled Fz 7tm_2 Dicty_CAR DUF5083

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

OMIM:

HGNC:

Ensembl:

Vega:

Pharos:

Q9UP38(Tbio)

UniProt:

Q9UP38

Position

7q21.13

AA seq 647 aa
MAEEEAPKKSRAAGGGASWELCAGALSARLAEEGSGDAGGRRRPPVDPRRLARQLLLLLW
LLEAPLLLGVRAQAAGQGPGQGPGPGQQPPPPPQQQQSGQQYNGERGISVPDHGYCQPIS
IPLCTDIAYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSAELKFFLCSMYAPVCTVL
EQALPPCRSLCERARQGCEALMNKFGFQWPDTLKCEKFPVHGAGELCVGQNTSDKGTPTP
SLLPEFWTSNPQHGGGGHRGGFPGGAGASERGKFSCPRALKVPSYLNYHFLGEKDCGAPC
EPTKVYGLMYFGPEELRFSRTWIGIWSVLCCASTLFTVLTYLVDMRRFSYPERPIIFLSG
CYTAVAVAYIAGFLLEDRVVCNDKFAEDGARTVAQGTKKEGCTILFMMLYFFSMASSIWW
VILSLTWFLAAGMKWGHEAIEANSQYFHLAAWAVPAIKTITILALGQVDGDVLSGVCFVG
LNNVDALRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDGTKTEKLEKLMVRIGVF
SVLYTVPATIVIACYFYEQAFRDQWERSWVAQSCKSYAIPCPHLQAGGGAPPHPPMSPDF
TVFMIKYLMTLIVGITSGFWIWSGKTLNSWRKFYTRLTNSKQGETTV

NT seq 1944 nt +upstreamnt +downstreamnt
atggctgaggaggaggcgcctaagaagtcccgggccgccggcggtggcgcgagctgggaa
ctttgtgccggggcgctctcggcccggctggcggaggagggcagcggggacgccggtggc
cgccgccgcccgccagttgacccccggcgattggcgcgccagctgctgctgctgctttgg
ctgctggaggctccgctgctgctgggggtccgggcccaggcggcgggccaggggccaggc
caggggcccgggccggggcagcaaccgccgccgccgcctcagcagcaacagagcgggcag
cagtacaacggcgagcggggcatctccgtcccggaccacggctattgccagcccatctcc
atcccgctgtgcacggacatcgcgtacaaccagaccatcatgcccaacctgctgggccac
acgaaccaggaggacgcgggcctggaggtgcaccagttctaccctctagtgaaagtgcag
tgttccgctgagctcaagttcttcctgtgctccatgtacgcgcccgtgtgcaccgtgcta
gagcaggcgctgccgccctgccgctccctgtgcgagcgcgcgcgccagggctgcgaggcg
ctcatgaacaagttcggcttccagtggccagacacgctcaagtgtgagaagttcccggtg
cacggcgccggcgagctgtgcgtgggccagaacacgtccgacaagggcaccccgacgccc
tcgctgcttccagagttctggaccagcaaccctcagcacggcggcggagggcaccgtggc
ggcttcccggggggcgccggcgcgtcggagcgaggcaagttctcctgcccgcgcgccctc
aaggtgccctcctacctcaactaccacttcctgggggagaaggactgcggcgcaccttgt
gagccgaccaaggtgtatgggctcatgtacttcgggcccgaggagctgcgcttctcgcgc
acctggattggcatttggtcagtgctgtgctgcgcctccacgctcttcacggtgcttacg
tacctggtggacatgcggcgcttcagctacccggagcggcccatcatcttcttgtccggc
tgttacacggccgtggccgtggcctacatcgccggcttcctcctggaagaccgagtggtg
tgtaatgacaagttcgccgaggacggggcacgcactgtggcgcagggcaccaagaaggag
ggctgcaccatcctcttcatgatgctctacttcttcagcatggccagctccatctggtgg
gtgatcctgtcgctcacctggttcctggcggctggcatgaagtggggccacgaggccatc
gaagccaactcacagtattttcacctggccgcctgggctgtgccggccatcaagaccatc
accatcctggcgctgggccaggtggacggcgatgtgctgagcggagtgtgcttcgtgggg
cttaacaacgtggacgcgctgcgtggcttcgtgctggcgcccctcttcgtgtacctgttt
atcggcacgtcctttctgctggccggctttgtgtcgctcttccgcatccgcaccatcatg
aagcacgatggcaccaagaccgagaagctggagaagctcatggtgcgcattggcgtcttc
agcgtgctgtacactgtgccagccaccatcgtcatcgcctgctacttctacgagcaggcc
ttccgggaccagtgggaacgcagctgggtggcccagagctgcaagagctacgctatcccc
tgccctcacctccaggcgggcggaggcgccccgccgcacccgcccatgagcccggacttc
acggtcttcatgattaagtaccttatgacgctgatcgtgggcatcacgtcgggcttctgg
atctggtccggcaagaccctcaactcctggaggaagttctacacgaggctcaccaacagc
aaacaaggggagactacagtctga

All links

Ontology (3)   
   KEGG BRITE (3)   
Pathway (15)   
   KEGG PATHWAY (14)   
   KEGG MODULE (1)   
Network (2)   
   KEGG NETWORK (2)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (13)   
   KEGG ORTHOLOGY (1)   
   RefGene (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   UniGene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (13)   
   RefSeq(nuc) (1)   
   GenBank (6)   
   EMBL (6)   
Protein domain (5)   
   Pfam (5)   
All databases (56)   

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