KEGG   Homo sapiens (human): 8394Help
Entry
8394              CDS       T01001                                 

Gene name
PIP5K1A
Definition
phosphatidylinositol-4-phosphate 5-kinase, type I, alpha (EC:2.7.1.68)
Orthology
K00889  
1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
Organism
hsa  Homo sapiens (human)
Pathway
Inositol phosphate metabolism
Metabolic pathways
Phosphatidylinositol signaling system
Endocytosis
Fc gamma R-mediated phagocytosis
Regulation of actin cytoskeleton
Module
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    8394 (PIP5K1A)
 Environmental Information Processing
  Signal transduction
   04070 Phosphatidylinositol signaling system
    8394 (PIP5K1A)
 Cellular Processes
  Transport and catabolism
   04144 Endocytosis
    8394 (PIP5K1A)
  Cell motility
   04810 Regulation of actin cytoskeleton
    8394 (PIP5K1A)
 Organismal Systems
  Immune system
   04666 Fc gamma R-mediated phagocytosis
    8394 (PIP5K1A)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.68  1-phosphatidylinositol-4-phosphate 5-kinase
     8394 (PIP5K1A)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 
Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
OMIM: 
HGNC: 
Ensembl: 
Vega: 
UniProt: 
Position
1q21.3
AA seq 522 aa AA seqDB search
MASASSGPSSSVGFSSFDPAVPSCTLSSAASGIKRPMASEVPYASGMPIKKIGHRSVDSS
GETTYKKTTSSALKGAIQLGITHTVGSLSTKPERDVLMQDFYVVESIFFPSEGSNLTPAH
HYNDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCSEPLIELCSSGASGSLFYVSSDDEFI
IKTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQAGGKNIRIVVMNNLLPRSV
KMHIKYDLKGSTYKRRASQKEREKPLPTFKDLDFLQDIPDGLFLDADMYNALCKTLQRDC
LVLQSFKIMDYSLLMSIHNIDHAQREPLSSETQYSVDTRRPAPQKALYSTAMESIQGEAR
RGGTMETDDQFVKKLEHSWKALVHDGDTVSVHRPGFYAERFQRFMCNTVFKKIPLKPSPS
KKFRSGSSFSRRAGSSGNSCITYQPSVSGEHKAQVTTKAEVEPGVHLGRPDVLPQTPPLE
EISEGSPIPDPSFSPLVGETLQMLTTSTTLEKLEVAESEFTH
NT seq 1569 nt NT seq  +upstreamnt  +downstreamnt
atggcgtcggcctcctccgggccgtcgtcttcggtcggtttttcatcctttgatcccgcg
gtcccttcctgtaccttgtcctcagcagcatctggaatcaagagacccatggcatctgag
gtgccttatgcctctggcatgcccatcaagaaaataggccatagaagtgttgattcctca
ggagagacaacatataaaaagacaacctcatcagccttgaaaggtgccatccagttaggc
attacccacactgtggggagcctgagtaccaaaccagagcgtgatgtcctcatgcaagat
ttctacgtggttgagagtatcttctttcccagtgaagggagcaacctgacccctgctcat
cactacaatgactttcgtttcaagacctatgcacctgttgccttccgctacttccgggag
ctatttggtatccggcccgatgattacttgtattccctctgcagtgagccgctgattgaa
ctctgtagctctggagctagtggttccctattctatgtgtccagcgacgatgagttcatt
attaagacagtccaacataaagaggcggaatttctgcagaagctgcttccaggatactac
atgaacctcaaccagaaccctcggactttgctgcctaaattctatggactgtactgtgtg
caggcaggtggcaagaacattcggattgtggtgatgaacaatcttttaccaagatcggta
aaaatgcatatcaaatatgacctcaaaggctcaacctacaaacggcgggcttcccagaaa
gagcgagagaagcctcttcccacatttaaagacctagacttcttacaagacatccctgat
ggtctttttttggatgctgacatgtacaacgctctctgtaagaccctgcagcgtgactgt
ttggtgctgcagagcttcaagataatggattacagcctcttgatgtcaatccataatata
gatcatgcacaacgagagcccttaagcagtgaaacacagtactcagttgatactcgaaga
ccggccccccaaaaggctctgtattccacagccatggaatccatccagggagaggctcga
cggggtggtaccatggagactgatgaccagtttgttaagaagttggagcactcttggaaa
gccctggtacatgacggagacactgtctcagtgcatcgcccaggcttctacgctgaacgg
ttccagcgcttcatgtgcaacacagtatttaagaagattcccttgaagccttctccttcc
aaaaagtttcggtctggctcatctttctctcggcgagcaggctccagtggcaactcctgc
attacttaccagccatcggtctctggggaacacaaggcacaagtgacaacaaaggcagaa
gtggagccaggcgttcaccttggtcgtcctgatgttttacctcagactccacctttggag
gaaatcagtgagggctcgcctattcctgaccccagtttctcacctctagttggagagact
ttgcaaatgctaactacaagtacaaccttggaaaagcttgaagttgcagagtcagagttc
acccattaa

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