KEGG   Homo sapiens (human): 8395Help
Entry
8395              CDS       T01001                                 

Gene name
PIP5K1B, MSS4, STM7
Definition
(RefSeq) phosphatidylinositol-4-phosphate 5-kinase, type I, beta (EC:2.7.1.68)
  KO
K00889  
1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
Organism
hsa  Homo sapiens (human)
Pathway
Inositol phosphate metabolism
Metabolic pathways
Phosphatidylinositol signaling system
Phospholipase D signaling pathway
Endocytosis
Fc gamma R-mediated phagocytosis
Regulation of actin cytoskeleton
Choline metabolism in cancer
Module
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    8395 (PIP5K1B)
 Environmental Information Processing
  Signal transduction
   04070 Phosphatidylinositol signaling system
    8395 (PIP5K1B)
   04072 Phospholipase D signaling pathway
    8395 (PIP5K1B)
 Cellular Processes
  Transport and catabolism
   04144 Endocytosis
    8395 (PIP5K1B)
  Cell motility
   04810 Regulation of actin cytoskeleton
    8395 (PIP5K1B)
 Organismal Systems
  Immune system
   04666 Fc gamma R-mediated phagocytosis
    8395 (PIP5K1B)
 Human Diseases
  Cancers
   05231 Choline metabolism in cancer
    8395 (PIP5K1B)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.68  1-phosphatidylinositol-4-phosphate 5-kinase
     8395 (PIP5K1B)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 
Motif
Other DBs
NCBI-ProteinID: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Position
9q13
AA seq 502 aa AA seqDB search
MSSAAENGEAAPGKQNEEKTYKKTASSAIKGAIQLGIGYTVGNLTSKPERDVLMQDFYVV
ESVFLPSEGSNLTPAHHYPDFRFKTYAPLAFRYFRELFGIKPDDYLYSICSEPLIELSNP
GASGSLFFVTSDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCMQSGG
INIRIVVMNNVLPRSMRMHFTYDLKGSTYKRRASRKEREKSNPTFKDLDFLQDMHEGLYF
DTETYNALMKTLQRDCRVLESFKIMDYSLLLGIHFLDHSLKEKEEETPQNVPDAKRTGMQ
KVLYSTAMESIQGPGKSGDGIITENPDTMGGIPAKSHRGEKLLLFMGIIDILQSYRLMKK
LEHSWKALVYDGDTVSVHRPSFYADRFLKFMNSRVFKKIQALKASPSKKRCNSIAALKAT
SQEIVSSISQEWKDEKRDLLTEGQSFSSLDEEALGSRHRPDLVPSTPSLFEAASLATTIS
SSSLYVNEHYPHDRPTLYSNSK
NT seq 1509 nt NT seq  +upstreamnt  +downstreamnt
atgtcttctgctgctgaaaatggagaggcagcacctggaaaacaaaatgaagaaaaaacc
tataaaaagactgcatcatctgctattaaaggtgctattcagctgggaataggatacaca
gtgggtaatctcacttccaagccagaacgagatgttcttatgcaagacttttatgtggtg
gaaagtgtgttcctacccagcgaagggagcaatctgaccccagcacatcactacccagac
tttagatttaagacatacgctccattagcattccgatatttcagagaactttttggtatc
aagcctgatgattacttgtattccatctgcagtgaacctctaatagaactgtctaaccct
ggagccagtggatccttgttttttgtgaccagtgatgatgaatttatcatcaaaacagtt
cagcacaaagaagctgagtttcttcagaagctactgccaggctattacatgaatttaaac
cagaatccaaggactcttttgccaaaattttacggactgtattgtatgcaatcaggaggc
attaatatcaggattgtggtgatgaacaacgttttgccacgctccatgagaatgcacttt
acatatgacttgaaaggctcaacgtataagcgaagagcatcccgtaaagagagagagaaa
tccaaccccacatttaaggacttagatttcctgcaagacatgcacgaagggttgtatttt
gatacggaaacatacaacgcgcttatgaaaacacttcagagagactgccgggtgctagaa
agcttcaagatcatggattatagccttctgttgggaattcatttcctggaccattccctc
aaagagaaagaggaggagaccccacaaaatgtgcctgatgctaagcggactgggatgcag
aaggttctctactcaacagccatggaatctatccagggtccagggaaatctggagatggg
ataatcacagagaacccagacacaatgggaggcattccagctaaaagccataggggagaa
aaactacttttatttatgggcattattgacattctgcaatcatataggttaatgaagaag
ttagaacattcctggaaagctcttgtttatgatggggacactgtttctgttcatagacca
agcttttatgcagacagatttcttaagttcatgaattccagagttttcaagaaaattcaa
gctttgaaggcttcaccgtctaagaaacggtgcaattcaatcgccgccctaaaggccact
tcacaggagattgtgtcctcaattagccaggaatggaaggatgagaagcgggatttgctg
actgaaggacaaagttttagcagccttgatgaagaagccctgggatcccgacacaggcca
gacctggtccctagcactccatcactgtttgaagctgcttccttggcaaccacaatttca
tcttcttccttatacgtcaatgagcactatccacacgacaggcctacactctattcaaac
agtaagtga

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