KEGG   Homo sapiens (human): 8516Help
Entry
8516              CDS       T01001                                 

Gene name
ITGA8
Definition
integrin, alpha 8
Orthology
K06584  
integrin alpha 8
Organism
hsa  Homo sapiens (human)
Pathway
PI3K-Akt signaling pathway
Focal adhesion
ECM-receptor interaction
Cell adhesion molecules (CAMs)
Regulation of actin cytoskeleton
Hypertrophic cardiomyopathy (HCM)
Arrhythmogenic right ventricular cardiomyopathy (ARVC)
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04151 PI3K-Akt signaling pathway
    8516 (ITGA8)
  Signaling molecules and interaction
   04512 ECM-receptor interaction
    8516 (ITGA8)
   04514 Cell adhesion molecules (CAMs)
    8516 (ITGA8)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    8516 (ITGA8)
  Cell communication
   04510 Focal adhesion
    8516 (ITGA8)
 Human Diseases
  Cardiovascular diseases
   05410 Hypertrophic cardiomyopathy (HCM)
    8516 (ITGA8)
   05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC)
    8516 (ITGA8)
   05414 Dilated cardiomyopathy (DCM)
    8516 (ITGA8)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
UniProt: 
Position
10p13
AA seq 1048 aa AA seqDB search
MSPGASRGPRGSQAPLIAPLCCAAAALGMLLWSPACQAFNLDVEKLTVYSGPKGSYFGYA
VDFHIPDARTASVLVGAPKANTSQPDIVEGGAVYYCPWPAEGSAQCRQIPFDTTNNRKIR
VNGTKEPIEFKSNQWFGATVKAHKGKVVACAPLYHWRTLKPTPEKDPVGTCYVAIQNFSA
YAEFSPCRNSNADPEGQGYCQAGFSLDFYKNGDLIVGGPGSFYWQGQVITASVADIIANY
SFKDILRKLAGEKQTEVAPASYDDSYLELVAGIPRGAQNFGYVSIINSTDMTFIQNFTGE
QMASYFGYTVVVSDVNSDGLDDVLVGAPLFMEREFESNPREVGQIYLYLQVSSLLFRDPQ
ILTGTETFGRFGSAMAHLGDLNQDGYNDIAIGVPFAGKDQRGKVLIYNGNKDGLNTKPSQ
VLQGVWASHAVPSGFGFTLRGDSDIDKNDYPDLIVGAFGTGKVAVYRARPVVTVDAQLLL
HPMIINLENKTCQVPDSMTSAACFSLRVCASVTGQSIANTIVLMAEVQLDSLKQKGAIKR
TLFLDNHQAHRVFPLVIKRQKSHQCQDFIVYLRDETEFRDKLSPINISLNYSLDESTFKE
GLEVKPILNYYRENIVSEQAHILVDCGEDNLCVPDLKLSARPDKHQVIIGDENHLMLIIN
ARNEGEGAYEAELFVMIPEEADYVGIERNNKGFRPLSCEYKMENVTRMVVCDLGNPMVSG
TNYSLGLRFAVPRLEKTNMSINFDLQIRSSNKDNPDSNFVSLQINITAVAQVEIRGVSHP
PQIVLPIHNWEPEEEPHKEEEVGPLVEHIYELHNIGPSTISDTILEVGWPFSARDEFLLY
IFHIQTLGPLQCQPNPNINPQDIKPAASPEDTPELSAFLRNSTIPHLVRKRDVHVVEFHR
QSPAKILNCTNIECLQISCAVGRLEGGESAVLKVRSRLWAHTFLQRKNDPYALASLVSFE
VKKMPYTDQPAKLPEGSIVIKTSVIWATPNVSFSIPLWVIILAILLGLLVLAILTLALWK
CGFFDRARPPQEDMTDREQLTNDKTPEA
NT seq 3147 nt NT seq  +upstreamnt  +downstreamnt
atgtcgcccggggccagccgcggtccccggggaagccaggcgccgctgatcgcgcccctc
tgctgcgccgcggccgcgctggggatgttgctgtggtcccccgcctgtcaggcgttcaac
ctggacgtggaaaagctcacagtgtacagcggccccaagggcagctacttcggctacgcc
gtggacttccacatacccgacgcccgcacagcgagtgtcttggtgggggcgcccaaagcc
aacaccagccagcccgatatcgtggaagggggagccgtctattactgtccttggcccgcg
gaggggtctgcgcagtgcaggcagataccgtttgacaccaccaacaacagaaagatcaga
gttaatggaaccaaagaacctatcgagttcaaatccaatcagtggtttggagcaacagtg
aaagctcacaaaggaaaagttgtggcctgtgctcctttatatcactggagaactcttaaa
ccgacaccagaaaaggacccagttggcacctgctatgtagcaattcagaacttcagcgcc
tatgccgagttctctccttgccggaacagcaatgctgatccggaaggccagggttactgc
caagcaggatttagtctggatttttataagaatggagaccttattgtgggaggacctggg
agtttctactggcaaggacaagtgatcactgccagtgttgcagatatcattgcaaattac
tcattcaaggatatcctcaggaaactggcaggagaaaagcagacggaagtggctccagct
tcctatgatgacagttaccttgaattggttgctggaattccaagaggagcacagaatttt
ggatatgtttccatcattaactctacggatatgacgtttattcagaatttcacgggagaa
cagatggcatcttattttggatataccgttgtcgtatcagatgttaacagtgatggactg
gatgatgtcctggttggggcacctctctttatggaacgtgaatttgagagcaaccccaga
gaagtagggcaaatctacctgtatttgcaagtgagctctctcctcttcagagacccccag
atcctcactggcaccgagacgtttgggagattcggtagtgctatggcacacttaggagac
ctgaaccaagatggatacaatgacattgccatcggagtgccttttgcaggcaaggatcaa
agaggcaaagtgctcatttataatgggaacaaagatggcttaaacaccaagccttcccaa
gttctgcaaggagtgtgggcctcacatgctgtcccttccggatttggctttactttaaga
ggagattcagacatagacaagaatgattacccagatttgattgtgggtgcatttggaaca
ggaaaagtcgctgtttacagagcaagaccggttgtgactgtagatgcccagcttctgctg
cacccaatgattatcaatcttgaaaataaaacttgccaggttccagactctatgacatct
gctgcctgcttttctttaagagtatgtgcatctgtcacaggccagagcattgcaaacaca
atagtcttgatggcagaggtgcaattagattccctgaaacagaaaggagctattaaacgg
acgctcttccttgataaccatcaggctcatcgcgtcttccctcttgtgataaaaaggcag
aaatcccaccagtgccaggatttcatcgtttaccttcgagatgaaactgaattccgagat
aaattatctccaatcaacattagtttgaattacagtttggacgaatccacctttaaagaa
ggcctggaagtgaaaccaatattgaactactacagagaaaacattgttagtgaacaggct
cacattctggtggactgtggagaagacaatctgtgtgttcctgacttgaagctgtcggct
agaccagataagcatcaggtaatcattggagatgaaaatcaccttatgctcataataaat
gcaagaaatgaaggggaaggagcatatgaagctgaactctttgtaatgataccagaagag
gcagattatgttggaatcgaacgcaacaacaagggatttcgaccactgagctgtgagtac
aagatggaaaatgtaaccaggatggtggtgtgtgaccttgggaaccctatggtgtctgga
acaaattattccctgggcctccgatttgcagttccacgtcttgagaaaacaaacatgagc
attaacttcgatctccaaatcagaagttccaacaaggacaatccagacagcaattttgtg
agcctgcaaatcaacatcactgctgtagcgcaggtggaaataagaggagtgtcacaccct
ccgcagattgttctgcccattcataactgggaaccagaagaggagccccacaaagaggag
gaggttggaccattggtggaacatatttatgagctgcacaatattggaccaagtaccatc
agtgacaccatcctggaggtgggctggcctttctctgcccgggatgaatttcttctctat
attttccatattcaaactctgggacctctgcagtgccaaccaaatcctaatatcaatcca
caggatataaagcctgctgcctccccagaggacacccctgagctcagcgcctttttgcga
aactctactattcctcatcttgtcaggaagagggatgtacatgtggtcgaattccacaga
cagagccctgcaaaaatactgaattgtacaaatatcgagtgtttacaaatctcctgtgca
gtgggacgactcgaaggaggagaaagcgcagtcctgaaagtcaggtcacgattatgggcc
cacaccttcctccagagaaaaaatgatccctatgctcttgcatccctggtgtcctttgaa
gttaagaagatgccttatacagatcagccagcaaaactcccagaaggaagcatagtaatt
aagacatcagttatttgggcaactccgaatgtttccttctcaatcccattatgggtaata
atactagcaatacttcttggattgttggttctcgccattttaaccttagctttatggaag
tgtggattctttgacagagccagacctcctcaggaggacatgaccgacagggaacagctg
acaaatgacaagacccctgaggcatga

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