KEGG   Homo sapiens (human): 8605Help
Entry
8605              CDS       T01001                                 

Gene name
PLA2G4C, CPLA2-gamma
Definition
phospholipase A2, group IVC (cytosolic, calcium-independent) (EC:3.1.1.4)
Orthology
K16342  
cytosolic phospholipase A2 [EC:3.1.1.4]
Organism
hsa  Homo sapiens (human)
Pathway
Glycerophospholipid metabolism
Ether lipid metabolism
Arachidonic acid metabolism
Linoleic acid metabolism
alpha-Linolenic acid metabolism
Metabolic pathways
MAPK signaling pathway
Ras signaling pathway
Vascular smooth muscle contraction
VEGF signaling pathway
Platelet activation
Fc epsilon RI signaling pathway
Glutamatergic synapse
Serotonergic synapse
Long-term depression
Inflammatory mediator regulation of TRP channels
GnRH signaling pathway
Ovarian steroidogenesis
Oxytocin signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Metabolism
  Lipid metabolism
   00564 Glycerophospholipid metabolism
    8605 (PLA2G4C)
   00565 Ether lipid metabolism
    8605 (PLA2G4C)
   00590 Arachidonic acid metabolism
    8605 (PLA2G4C)
   00591 Linoleic acid metabolism
    8605 (PLA2G4C)
   00592 alpha-Linolenic acid metabolism
    8605 (PLA2G4C)
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    8605 (PLA2G4C)
   04010 MAPK signaling pathway
    8605 (PLA2G4C)
   04370 VEGF signaling pathway
    8605 (PLA2G4C)
 Organismal Systems
  Immune system
   04611 Platelet activation
    8605 (PLA2G4C)
   04664 Fc epsilon RI signaling pathway
    8605 (PLA2G4C)
  Endocrine system
   04912 GnRH signaling pathway
    8605 (PLA2G4C)
   04913 Ovarian Steroidogenesis
    8605 (PLA2G4C)
   04921 Oxytocin signaling pathway
    8605 (PLA2G4C)
  Circulatory system
   04270 Vascular smooth muscle contraction
    8605 (PLA2G4C)
  Nervous system
   04724 Glutamatergic synapse
    8605 (PLA2G4C)
   04726 Serotonergic synapse
    8605 (PLA2G4C)
   04730 Long-term depression
    8605 (PLA2G4C)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    8605 (PLA2G4C)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.1  Carboxylic-ester hydrolases
    3.1.1.4  phospholipase A2
     8605 (PLA2G4C)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Position
19q13.3
AA seq 551 aa AA seqDB search
MRTRPRPRLRRTENFLTAVHHGKKEEKAAVERRRLHVLKALKKLRIEADEAPVVAVLGSG
GGLRAHIACLGVLSEMKEQGLLDAVTYLAGVSGSTWAISSLYTNDGDMEALEADLKHRFT
RQEWDLAKSLQKTIQAARSENYSLTDFWAYMVISKQTRELPESHLSNMKKPVEEGTLPYP
IFAAIDNDLQPSWQEARAPETWFEFTPHHAGFSALGAFVSITHFGSKFKKGRLVRTHPER
DLTFLRGLWGSALGNTEVIREYIFDQLRNLTLKGLWRRAVANAKSIGHLIFARLLRLQES
SQGEHPPPEDEGGEPEHTWLTEMLENWTRTSLEKQEQPHEDPERKGSLSNLMDFVKKTGI
CASKWEWGTTHNFLYKHGGIRDKIMSSRKHLHLVDAGLAINTPFPLVLPPTREVHLILSF
DFSAGDPFETIRATTDYCRRHKIPFPQVEEAELDLWSKAPASCYILKGETGPVVMHFPLF
NIDACGGDIEAWSDTYDTFKLADTYTLDVVVLLLALAKKNVRENKKKILRELMNVAGLYY
PKDSARSCCLA
NT seq 1656 nt NT seq  +upstreamnt  +downstreamnt
atgcgcacacgccccagacccaggctcaggaggactgagaattttctgaccgcagtgcac
catgggaagaaagaagaaaaggcggccgtggagagacgaagacttcatgtgctgaaagct
ctgaagaagctaaggattgaggctgatgaggccccagttgttgctgtgctgggctcaggc
ggaggactgcgggctcacattgcctgccttggggtcctgagtgagatgaaagaacagggc
ctgttggatgccgtcacgtacctcgcaggggtctctggatccacttgggcaatatcttct
ctctacaccaatgatggtgacatggaagctctcgaggctgacctgaaacatcgatttacc
cgacaggagtgggacttggctaagagcctacagaaaaccatccaagcagcgaggtctgag
aattactctctgaccgacttctgggcctacatggttatctctaagcaaaccagagaactg
ccggagtctcatttgtccaatatgaagaagcccgtggaagaagggacactaccctaccca
atatttgcagccattgacaatgacctgcaaccttcctggcaggaggcaagagcaccagag
acctggttcgagttcacccctcaccacgctggcttctctgcactgggggcctttgtttcc
ataacccacttcggaagcaaattcaagaagggaagactggtcagaactcaccctgagaga
gacctgactttcctgagaggtttatggggaagtgctcttggtaacactgaagtcattagg
gaatacatttttgaccagttaaggaatctgaccctgaaaggtttatggagaagggctgtt
gctaatgctaaaagcattggacaccttatttttgcccgattactgaggctgcaagaaagt
tcacaaggggaacatcctcccccagaagatgaaggcggtgagcctgaacacacctggctg
actgagatgctcgagaattggaccaggacctccctggaaaagcaggagcagccccatgag
gaccccgaaaggaaaggctcactcagtaacttgatggattttgtgaagaaaacaggcatt
tgcgcttcaaagtgggaatgggggaccactcacaacttcctgtacaaacacggtggcatc
cgggacaagataatgagcagccggaagcacctccacctggtggatgctggtttagccatc
aacactcccttcccactcgtgctgcccccgacgcgggaggttcacctcatcctctccttc
gacttcagtgccggagatcctttcgagaccatccgggctaccactgactactgccgccgc
cacaagatcccctttccccaagtagaagaggctgagctggatttgtggtccaaggccccc
gccagctgctacatcctgaaaggagaaactggaccagtggtgatgcattttcccctgttc
aacatagatgcctgtggaggtgatattgaggcatggagtgacacatacgacacattcaag
cttgctgacacctacactctagatgtggtggtgctactcttggcattagccaagaagaat
gtcagggaaaacaagaagaagatccttagagagttgatgaacgtggccgggctctactac
ccgaaggatagtgcccgaagttgctgcttggcatag

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