KEGG T01001: 8973

Homo sapiens (human): 8973

Entry

8973 CDS T01001

Gene name

CHRNA6, CHNRA6

Definition

cholinergic receptor, nicotinic, alpha 6 (neuronal)

Orthology

K04808

nicotinic acetylcholine receptor alpha-6

Organism

hsa Homo sapiens (human)

Pathway

hsa04080	Neuroactive ligand-receptor interaction
hsa04725	Cholinergic synapse
hsa05033	Nicotine addiction

Drug target

Mecamylamine:

D00611

Acetylcholine:

D00999

Other:

D02202 D02204 D02364 D08138

Class

Environmental Information Processing; Signaling molecules and interaction; Neuroactive ligand-receptor interaction [PATH:hsa04080]
Organismal Systems; Nervous system; Cholinergic synapse [PATH:hsa04725]
Human Diseases; Substance dependence; Nicotine addiction [PATH:hsa05033]

SSDB

Motif

Pfam:

Neur_chan_memb Neur_chan_LBD

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

Position

8p11.21

AA seq 479 aa
MLTSKGQGFLHGGLCLWLCVFTPFFKGCVGCATEERLFHKLFSHYNQFIRPVENVSDPVT
VHFEVAITQLANVIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAVGDFQVEGK
TKALLKYNGMITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLIIGSKV
DMNDFWENSEWEIIDASGYKHDIKYNCCEEIYTDITYSFYIRRLPMFYTINLIIPCLFIS
FLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVVPLVGEYLLFTMIFVT
LSIVVTVFVLNIHYRTPTTHTMPRWVKTVFLKLLPQVLLMRWPLDKTRGTGSDAVPRGLA
RRPAKGKLASHGEPRHLKECFHCHKSNELATSKRRLSHQPLQWVVENSEHSPEVEDVINS
VQFIAENMKSHNETKEVEDDWKYVAMVVDRVFLWVFIIVCVFGTAGLFLQPLLGNTGKS

NT seq 1440 nt +upstreamnt +downstreamnt
atgctgaccagcaaggggcagggattccttcatgggggcttgtgtctctggctgtgtgtg
ttcacacctttctttaaaggctgtgtgggctgtgcaactgaggagaggctcttccacaaa
ctgttttctcattacaaccagttcatcaggcctgtggaaaacgtttccgaccctgtcacg
gtacactttgaagtggccatcacccagctggccaacgtgatctggaatgattataaattg
cgctgggatccaatggaatatgatggcattgagactcttcgcgttcctgcagataagatt
tggaagcccgacattgttctctataacaatgctgttggtgacttccaagtagaaggcaaa
acaaaagctcttcttaaatacaatggcatgataacctggactccaccagctatttttaag
agttcctgccctatggatatcacctttttcccttttgatcatcaaaactgttccctaaaa
tttggttcctggacgtatgacaaagctgaaattgatcttctaatcattggatcaaaagtg
gatatgaatgatttttgggaaaacagtgaatgggaaatcattgatgcctctggctacaaa
catgacatcaaatacaactgttgtgaagagatatacacagatataacctattctttctac
attagaagattgccgatgttttacacgattaatctgatcatcccttgtctctttatttca
tttctaaccgtgttggtcttttaccttccttcggactgtggtgaaaaagtgacgctttgt
atttcagtcctgctttctctgactgtgtttttgctggtcatcacagaaaccatcccatcc
acatctctggtggtcccactggtgggtgagtacctgctgttcaccatgatctttgtcaca
ctgtccatcgtggtgactgtgtttgtgttgaacatacactaccgcaccccaaccacgcac
acaatgcccaggtgggtgaagacagttttcctgaagctgctgccccaggtcctgctgatg
aggtggcctctggacaagacaaggggcacaggctctgatgcagtgcccagaggccttgcc
aggaggcctgccaaaggcaagcttgcaagccatggggaacccagacatcttaaagaatgc
ttccattgtcacaaatcaaatgagcttgccacaagcaagagaagattaagtcatcagcca
ttacagtgggtggtggaaaattcggagcactcgcctgaagttgaagatgtgattaacagt
gttcagttcatagcagaaaacatgaagagccacaatgaaaccaaggaggtagaagatgac
tggaaatacgtggccatggtggtggacagagtatttctttgggtatttataattgtctgt
gtatttggaactgcagggctatttctacagccactacttgggaacacaggaaaatcttaa

All links

Ontology (3)   
   KEGG BRITE (3)   
Pathway (3)   
   KEGG PATHWAY (3)   
Disease (1)   
   OMIM (1)   
Drug (6)   
   KEGG DRUG (6)   
Genome (1)   
   KEGG GENOME (1)   
Gene (15)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (7)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (16)   
   RefSeq(nuc) (2)   
   GenBank (7)   
   EMBL (7)   
Protein domain (2)   
   Pfam (2)   
All databases (50)   

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