KEGG   Homo sapiens (human): 9064Help
Entry
9064              CDS       T01001                                 

Gene name
MAP3K6, ASK2, MAPKKK6, MEKK6
Definition
mitogen-activated protein kinase kinase kinase 6 (EC:2.7.11.25)
Orthology
K04425  
mitogen-activated protein kinase kinase kinase 6 [EC:2.7.11.25]
Organism
hsa  Homo sapiens (human)
Pathway
MAPK signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    9064 (MAP3K6)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.25  mitogen-activated protein kinase kinase kinase
     9064 (MAP3K6)
Protein kinases [BR:hsa01001]
 Serine/threonine protein kinases: STE group
  STE11 family
   9064 (MAP3K6)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Position
1p36.11
AA seq 1288 aa AA seqDB search
MAGPCPRSGAERAGSCWQDPLAVALSRGRQLAAPPGRGCARSRPLSVVYVLTREPQPGLE
PREGTEAEPLPLRCLREACAQVPRPRPPPQLRSLPFGTLELGDTAALDAFYNADVVVLEV
SSSLVQPSLFYHLGVRESFSMTNNVLLCSQADLPDLQALREDVFQKNSDCVGSYTLIPYV
VTATGRVLCGDAGLLRGLADGLVQAGVGTEALLTPLVGRLARLLEATPTDSCGYFRETIR
RDIRQARERFSGPQLRQELARLQRRLDSVELLSPDIIMNLLLSYRDVQDYSAIIELVETL
QALPTCDVAEQHNVCFHYTFALNRRNRPGDRAKALSVLLPLVQLEGSVAPDLYCMCGRIY
KDMFFSSGFQDAGHREQAYHWYRKAFDVEPSLHSGINAAVLLIAAGQHFEDSKELRLIGM
KLGCLLARKGCVEKMQYYWDVGFYLGAQILANDPTQVVLAAEQLYKLNAPIWYLVSVMET
FLLYQHFRPTPEPPGGPPRRAHFWLHFLLQSCQPFKTACAQGDQCLVLVLEMNKVLLPAK
LEVRGTDPVSTVTLSLLEPETQDIPSSWTFPVASICGVSASKRDERCCFLYALPPAQDVQ
LCFPSVGHCQWFCGLIQAWVTNPDSTAPAEEAEGAGEMLEFDYEYTETGERLVLGKGTYG
VVYAGRDRHTRVRIAIKEIPERDSRFSQPLHEEIALHRRLRHKNIVRYLGSASQGGYLKI
FMEEVPGGSLSSLLRSVWGPLKDNESTISFYTRQILQGLGYLHDNHIVHRDIKGDNVLIN
TFSGLLKISDFGTSKRLAGITPCTETFTGTLQYMAPEIIDQGPRGYGKAADIWSLGCTVI
EMATGRPPFHELGSPQAAMFQVGMYKVHPPMPSSLSAEAQAFLLRTFEPDPRLRASAQTL
LGDPFLQPGKRSRSPSSPRHAPRPSDAPSASPTPSANSTTQSQTFPCPQAPSQHPPSPPK
RCLSYGGTSQLRVPEEPAAEEPASPEESSGLSLLHQESKRRAMLAAVLEQELPALAENLH
QEQKQEQGARLGRNHVEELLRCLGAHIHTPNRRQLAQELRALQGRLRAQGLGPALLHRPL
FAFPDAVKQILRKRQIRPHWMFVLDSLLSRAVRAALGVLGPEVEKEAVSPRSEELSNEGD
SQQSPGQQSPLPVEPEQGPAPLMVQLSLLRAETDRLREILAGKEREYQALVQRALQRLNE
EARTYVLAPEPPTALSTDQGLVQWLQELNVDSGTIQMLLNHSFTLHTLLTYATRDDLIYT
RIRGGMVCRIWRAILAQRAGSTPVTSGP
NT seq 3867 nt NT seq  +upstreamnt  +downstreamnt
atggcggggccgtgtccccggtccggggcggagcgcgccggcagctgctggcaggacccg
ctggccgtggcgctgagccggggccggcagctcgcggcgcccccgggccggggctgcgcg
cggagccggccgctcagcgtggtctacgtgctgacccgggagccgcagcccgggctcgag
cctcgggagggaaccgaggcggagccgctgcccctgcgctgcctgcgcgaggcttgcgcg
caggtcccccggccgcggccgcccccgcagctgcgcagcctgcccttcgggacgctggag
ctaggcgacaccgcggctctggatgccttctacaacgcggatgtggtggtgctggaggtg
agcagctcgctggtacagccctccctgttctaccaccttggtgtgcgtgagagcttcagc
atgaccaacaatgtgctcctctgctcccaggccgacctccctgacctgcaggccctgcgg
gaggatgttttccagaagaactcggattgcgttggcagctacacactgatcccctatgtg
gtgacggccactggtcgggtgctgtgtggtgatgcaggccttctgcggggcctggctgat
gggctggtacaggctggagtggggaccgaggccctgctcactcccctggtgggccggctt
gcccgcctgctggaggccacacccacagactcttgtggctatttccgggagaccattcgg
cgggacatccggcaggcgcgggagcggttcagtgggccacagctgcggcaggagctggct
cgcctgcagcggagactggacagcgtggagctgctgagccccgacatcatcatgaacttg
ctgctctcctaccgcgatgtgcaggactactcggccatcattgagctggtggagacgctg
caggccttgcccacctgtgatgtggccgagcagcataatgtctgcttccactacactttt
gccctcaaccggaggaacaggcctggggaccgggcgaaggccctgtctgtgctgctgccg
ctggtacagcttgagggctctgtggcgcccgatctgtactgcatgtgtggccgtatctac
aaggacatgttcttcagctcgggtttccaggatgctgggcaccgggagcaggcctatcac
tggtatcgcaaggcttttgacgtagagcccagccttcactcaggcatcaatgcagctgtg
ctcctcattgctgccgggcagcactttgaggattccaaagagctccggctaataggcatg
aagctgggctgcctgctggcccgcaaaggctgcgtggagaagatgcagtattactgggat
gtgggtttctacctgggagcccagatcctcgccaatgaccccacccaggtggtgctggct
gcagagcagctgtataagctcaatgcccccatatggtacctggtgtccgtgatggagacc
ttcctgctctaccagcacttcaggcccacgccagagccccctggagggccaccacgccgt
gcccacttctggctccacttcttgctacagtcctgccaaccattcaagacagcctgtgcc
cagggcgaccagtgcttggtgctggtcctggagatgaacaaggtgctgctgcctgcaaag
ctcgaggttcggggtactgacccagtaagcacagtgaccctgagcctgctggagcctgag
acccaggacattccctccagctggaccttcccagtcgcctccatatgcggagtcagcgcc
tcaaagcgcgacgagcgctgctgcttcctctatgcactccccccggctcaggacgtccag
ctgtgcttccccagcgtagggcactgccagtggttctgcggcctgatccaggcctgggtg
acgaacccggattccacggcgcccgcggaggaggcggagggcgcgggggagatgttggag
tttgattatgagtacacggagacgggcgagcggctggtgctgggcaagggcacgtatggg
gtggtgtacgcgggccgcgatcgccacacgagggtgcgcatcgccatcaaggagatcccg
gagcgggacagcaggttctctcagcccctgcatgaagagatcgctcttcacagacgcctg
cgccacaagaacatagtgcgctatctgggctcagctagccagggcggctaccttaagatc
ttcatggaggaagtgcctggaggcagcctgtcctccttgctgcggtcggtgtggggaccc
ctgaaggacaacgagagcaccatcagtttctacacccgccagatcctgcagggacttggc
tacttgcacgacaaccacatcgtgcacagggacataaaaggggacaatgtgctgatcaac
accttcagtgggctgctcaagatttctgacttcggcacctccaagcggctggcaggcatc
acaccttgcactgagaccttcacaggaactctgcagtatatggccccagaaatcattgac
cagggcccacgcgggtatgggaaagcagctgacatctggtcactgggctgcactgtcatt
gagatggccacaggtcgcccccccttccacgagctcgggagcccacaggctgccatgttt
caggtgggtatgtacaaggtccatccgccaatgcccagctctctgtcggccgaggcccaa
gcctttctcctccgaacttttgagccagacccccgcctccgagccagcgcccagacactg
ctgggggaccccttcctgcagcctgggaaaaggagccgcagccccagctccccacgacat
gctccacggccctcagatgccccttctgccagtcccactccttcagccaactcaaccacc
cagtctcagacattcccgtgccctcaggcaccctctcagcacccacccagccccccgaag
cgctgcctcagttatgggggcaccagccagctccgggtgcccgaggagcctgcggccgag
gagcctgcgtctccggaggagagttcggggctgagcctgctgcaccaggagagcaagcgt
cgggccatgctggccgcagtattggagcaggagctgccagcgctggcggagaatctgcac
caggagcagaagcaagagcagggggcccgtctgggcagaaaccatgtggaagagctgctg
cgctgcctcggggcacacatccacactcccaaccgccggcagctcgcccaggagctgcgg
gcgctgcaaggacggctgagggcccagggccttgggcctgcgcttctgcacagaccgctg
tttgccttcccggatgcggtgaagcagatcctccgcaagcgccagatccgtccacactgg
atgttcgttctggactcactgctcagccgtgctgtgcgggcagccctgggtgtgctagga
ccggaggtggagaaggaggcggtctcaccgaggtcagaggagctgagtaatgaaggggac
tcccagcagagcccaggccagcagagcccgcttccggtggagcccgagcagggccccgct
cctctgatggtgcagctgagcctcttgagggcagagactgatcggctgcgcgaaatcctg
gcggggaaggaacgggagtaccaggccctggtgcagcgggctctacagcggctgaatgag
gaagcccggacctatgtcctggccccagagcctccaactgctctttcaacggaccagggc
ctggtgcagtggctacaggaactgaatgtggattcaggcaccatccaaatgctgttgaac
catagcttcaccctccacactctgctcacctatgccactcgagatgacctcatctacacc
cgcatcaggggagggatggtatgccgcatctggagggccatcttggcacagcgagcagga
tccacaccagtcacctctggaccctga

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