KEGG   Homo sapiens (human): 9064Help
Entry
9064              CDS       T01001                                 

Gene name
MAP3K6, ASK2, MAPKKK6, MEKK6
Definition
mitogen-activated protein kinase kinase kinase 6 (EC:2.7.11.25)
Orthology
K04425  
mitogen-activated protein kinase kinase kinase 6 [EC:2.7.11.25]
Organism
hsa  Homo sapiens (human)
Pathway
MAPK signaling pathway
Module
MAPK (JNK) signaling
MAPK (p38) signaling
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    9064 (MAP3K6)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.25  mitogen-activated protein kinase kinase kinase
     9064 (MAP3K6)
Protein kinases [BR:hsa01001]
 Serine/threonine protein kinases: STE group
  STE11 family
   9064 (MAP3K6)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Position
1p36.11
AA seq 1280 aa AA seqDB search
MAGPCPRSGAERAGSCWQDPLAVALSRGRQLAAPPGRGCARSRPLSVVYVLTREPQPGLE
PREGTEAEPLPLRCLREACAQVPRPRPPPQLRSLPFGTLELGDTAALDAFYNADVVVLEV
SSSLVQPSLFYHLGVRESFSMTNNVLLCSQADLPDLQALRDCVGSYTLIPYVVTATGRVL
CGDAGLLRGLADGLVQAGVGTEALLTPLVGRLARLLEATPTDSCGYFRETIRRDIRQARE
RFSGPQLRQELARLQRRLDSVELLSPDIIMNLLLSYRDVQDYSAIIELVETLQALPTCDV
AEQHNVCFHYTFALNRRNRPGDRAKALSVLLPLVQLEGSVAPDLYCMCGRIYKDMFFSSG
FQDAGHREQAYHWYRKAFDVEPSLHSGINAAVLLIAAGQHFEDSKELRLIGMKLGCLLAR
KGCVEKMQYYWDVGFYLGAQILANDPTQVVLAAEQLYKLNAPIWYLVSVMETFLLYQHFR
PTPEPPGGPPRRAHFWLHFLLQSCQPFKTACAQGDQCLVLVLEMNKVLLPAKLEVRGTDP
VSTVTLSLLEPETQDIPSSWTFPVASICGVSASKRDERCCFLYALPPAQDVQLCFPSVGH
CQWFCGLIQAWVTNPDSTAPAEEAEGAGEMLEFDYEYTETGERLVLGKGTYGVVYAGRDR
HTRVRIAIKEIPERDSRFSQPLHEEIALHRRLRHKNIVRYLGSASQGGYLKIFMEEVPGG
SLSSLLRSVWGPLKDNESTISFYTRQILQGLGYLHDNHIVHRDIKGDNVLINTFSGLLKI
SDFGTSKRLAGITPCTETFTGTLQYMAPEIIDQGPRGYGKAADIWSLGCTVIEMATGRPP
FHELGSPQAAMFQVGMYKVHPPMPSSLSAEAQAFLLRTFEPDPRLRASAQTLLGDPFLQP
GKRSRSPSSPRHAPRPSDAPSASPTPSANSTTQSQTFPCPQAPSQHPPSPPKRCLSYGGT
SQLRVPEEPAAEEPASPEESSGLSLLHQESKRRAMLAAVLEQELPALAENLHQEQKQEQG
ARLGRNHVEELLRCLGAHIHTPNRRQLAQELRALQGRLRAQGLGPALLHRPLFAFPDAVK
QILRKRQIRPHWMFVLDSLLSRAVRAALGVLGPEVEKEAVSPRSEELSNEGDSQQSPGQQ
SPLPVEPEQGPAPLMVQLSLLRAETDRLREILAGKEREYQALVQRALQRLNEEARTYVLA
PEPPTALSTDQGLVQWLQELNVDSGTIQMLLNHSFTLHTLLTYATRDDLIYTRIRGGMVC
RIWRAILAQRAGSTPVTSGP
NT seq 3843 nt NT seq  +upstreamnt  +downstreamnt
atggcggggccgtgtccccggtccggggcggagcgcgccggcagctgctggcaggacccg
ctggccgtggcgctgagccggggccggcagctcgcggcgcccccgggccggggctgcgcg
cggagccggccgctcagcgtggtctacgtgctgacccgggagccgcagcccgggctcgag
cctcgggagggaaccgaggcggagccgctgcccctgcgctgcctgcgcgaggcttgcgcg
caggtcccccggccgcggccgcccccgcagctgcgcagcctgcccttcgggacgctggag
ctaggcgacaccgcggctctggatgccttctacaacgcggatgtggtggtgctggaggtg
agcagctcgctggtacagccctccctgttctaccaccttggtgtgcgtgagagcttcagc
atgaccaacaatgtgctcctctgctcccaggccgacctccctgacctgcaggccctgcgg
gattgcgttggcagctacacactgatcccctatgtggtgacggccactggtcgggtgctg
tgtggtgatgcaggccttctgcggggcctggctgatgggctggtacaggctggagtgggg
accgaggccctgctcactcccctggtgggccggcttgcccgcctgctggaggccacaccc
acagactcttgtggctatttccgggagaccattcggcgggacatccggcaggcgcgggag
cggttcagtgggccacagctgcggcaggagctggctcgcctgcagcggagactggacagc
gtggagctgctgagccccgacatcatcatgaacttgctgctctcctaccgcgatgtgcag
gactactcggccatcattgagctggtggagacgctgcaggccttgcccacctgtgatgtg
gccgagcagcataatgtctgcttccactacacttttgccctcaaccggaggaacaggcct
ggggaccgggcgaaggccctgtctgtgctgctgccgctggtacagcttgagggctctgtg
gcgcccgatctgtactgcatgtgtggccgtatctacaaggacatgttcttcagctcgggt
ttccaggatgctgggcaccgggagcaggcctatcactggtatcgcaaggcttttgacgta
gagcccagccttcactcaggcatcaatgcagctgtgctcctcattgctgccgggcagcac
tttgaggattccaaagagctccggctaataggcatgaagctgggctgcctgctggcccgc
aaaggctgcgtggagaagatgcagtattactgggatgtgggtttctacctgggagcccag
atcctcgccaatgaccccacccaggtggtgctggctgcagagcagctgtataagctcaat
gcccccatatggtacctggtgtccgtgatggagaccttcctgctctaccagcacttcagg
cccacgccagagccccctggagggccaccacgccgtgcccacttctggctccacttcttg
ctacagtcctgccaaccattcaagacagcctgtgcccagggcgaccagtgcttggtgctg
gtcctggagatgaacaaggtgctgctgcctgcaaagctcgaggttcggggtactgaccca
gtaagcacagtgaccctgagcctgctggagcctgagacccaggacattccctccagctgg
accttcccagtcgcctccatatgcggagtcagcgcctcaaagcgcgacgagcgctgctgc
ttcctctatgcactccccccggctcaggacgtccagctgtgcttccccagcgtagggcac
tgccagtggttctgcggcctgatccaggcctgggtgacgaacccggattccacggcgccc
gcggaggaggcggagggcgcgggggagatgttggagtttgattatgagtacacggagacg
ggcgagcggctggtgctgggcaagggcacgtatggggtggtgtacgcgggccgcgatcgc
cacacgagggtgcgcatcgccatcaaggagatcccggagcgggacagcaggttctctcag
cccctgcatgaagagatcgctcttcacagacgcctgcgccacaagaacatagtgcgctat
ctgggctcagctagccagggcggctaccttaagatcttcatggaggaagtgcctggaggc
agcctgtcctccttgctgcggtcggtgtggggacccctgaaggacaacgagagcaccatc
agtttctacacccgccagatcctgcagggacttggctacttgcacgacaaccacatcgtg
cacagggacataaaaggggacaatgtgctgatcaacaccttcagtgggctgctcaagatt
tctgacttcggcacctccaagcggctggcaggcatcacaccttgcactgagaccttcaca
ggaactctgcagtatatggccccagaaatcattgaccagggcccacgcgggtatgggaaa
gcagctgacatctggtcactgggctgcactgtcattgagatggccacaggtcgccccccc
ttccacgagctcgggagcccacaggctgccatgtttcaggtgggtatgtacaaggtccat
ccgccaatgcccagctctctgtcggccgaggcccaagcctttctcctccgaacttttgag
ccagacccccgcctccgagccagcgcccagacactgctgggggaccccttcctgcagcct
gggaaaaggagccgcagccccagctccccacgacatgctccacggccctcagatgcccct
tctgccagtcccactccttcagccaactcaaccacccagtctcagacattcccgtgccct
caggcaccctctcagcacccacccagccccccgaagcgctgcctcagttatgggggcacc
agccagctccgggtgcccgaggagcctgcggccgaggagcctgcgtctccggaggagagt
tcggggctgagcctgctgcaccaggagagcaagcgtcgggccatgctggccgcagtattg
gagcaggagctgccagcgctggcggagaatctgcaccaggagcagaagcaagagcagggg
gcccgtctgggcagaaaccatgtggaagagctgctgcgctgcctcggggcacacatccac
actcccaaccgccggcagctcgcccaggagctgcgggcgctgcaaggacggctgagggcc
cagggccttgggcctgcgcttctgcacagaccgctgtttgccttcccggatgcggtgaag
cagatcctccgcaagcgccagatccgtccacactggatgttcgttctggactcactgctc
agccgtgctgtgcgggcagccctgggtgtgctaggaccggaggtggagaaggaggcggtc
tcaccgaggtcagaggagctgagtaatgaaggggactcccagcagagcccaggccagcag
agcccgcttccggtggagcccgagcagggccccgctcctctgatggtgcagctgagcctc
ttgagggcagagactgatcggctgcgcgaaatcctggcggggaaggaacgggagtaccag
gccctggtgcagcgggctctacagcggctgaatgaggaagcccggacctatgtcctggcc
ccagagcctccaactgctctttcaacggaccagggcctggtgcagtggctacaggaactg
aatgtggattcaggcaccatccaaatgctgttgaaccatagcttcaccctccacactctg
ctcacctatgccactcgagatgacctcatctacacccgcatcaggggagggatggtatgc
cgcatctggagggccatcttggcacagcgagcaggatccacaccagtcacctctggaccc
tga

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