KEGG T01001: 9252

Homo sapiens (human): 9252

Entry

9252 CDS T01001

Gene name

RPS6KA5, MSK1, MSPK1, RLPK

Definition

ribosomal protein S6 kinase, 90kDa, polypeptide 5 (EC:2.7.11.1)

Orthology

K04445

ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]

Organism

hsa Homo sapiens (human)

Pathway

hsa04010	MAPK signaling pathway
hsa04713	Circadian entrainment
hsa04722	Neurotrophin signaling pathway
hsa05219	Bladder cancer

Class

Environmental Information Processing; Signal transduction; MAPK signaling pathway [PATH:hsa04010]
Organismal Systems; Nervous system; Neurotrophin signaling pathway [PATH:hsa04722]
Organismal Systems; Environmental adaptation; Circadian entrainment [PATH:hsa04713]
Human Diseases; Cancers; Bladder cancer [PATH:hsa05219]

SSDB

Motif

Pfam:

Pkinase Pkinase_Tyr Kinase-like Kdo APH Pkinase_C RIO1 Choline_kinase YrbL-PhoP_reg

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

Structure

PDB:

3KN6 3KN5 1VZO

Position

14q31-q32.1

AA seq 802 aa
MEEEGGSSGGAAGTSADGGDGGEQLLTVKHELRTANLTGHAEKVGIENFELLKVLGTGAY
GKVFLVRKISGHDTGKLYAMKVLKKATIVQKAKTTEHTRTERQVLEHIRQSPFLVTLHYA
FQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLALEHLHKLGIIYRDIKL
ENILLDSNGHVVLTDFGLSKEFVADETERAYSFCGTIEYMAPDIVRGGDSGHDKAVDWWS
LGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSALAKDLIQRLLMKDPKK
RLGCGPRDADEIKEHLFFQKINWDDLAAKKVPAPFKPVIRDELDVSNFAEEFTEMDPTYS
PAALPQSSEKLFQGYSFVAPSILFKRNAAVIDPLQFHMGVERPGVTNVARSAMMKDSPFY
QHYDLDLKDKPLGEGSFSICRKCVHKKSNQAFAVKIISKRMEANTQKEITALKLCEGHPN
IVKLHEVFHDQLHTFLVMELLNGGELFERIKKKKHFSETEASYIMRKLVSAVSHMHDVGV
VHRDLKPENLLFTDENDNLEIKIIDFGFARLKPPDNQPLKTPCFTLHYAAPELLNQNGYD
ESCDLWSLGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFEGEAWKNVSQEA
KDLIQGLLTVDPNKRLKMSGLRYNEWLQDGSQLSSNPLMTPDILGSSGAAVHTCVKATFH
AFNKYKREGFCLQNVDKAPLAKRRKMKKTSTSTETRSSSSESSHSSSSHSHGKTTPTKTL
QPSNPADSNNPETLFQFSDSVA

NT seq 2409 nt +upstreamnt +downstreamnt
atggaggaggagggtggcagcagcggcggcgccgcggggaccagcgcggacggcggcgac
ggaggagagcagctcctcactgtcaagcacgagctgcggactgctaatttgacaggacat
gctgagaaggtgggaatagaaaattttgagctcctgaaggtcctaggaactggagcttat
ggaaaagtatttctagttcgtaaaataagtggccatgatactggaaagctgtatgccatg
aaagttttgaaaaaggcaacaatcgttcaaaaggccaaaaccacagagcatacaaggaca
gaacgacaagtcctggaacacattaggcagtcgccatttttggtaacattacattatgct
ttccagacagaaaccaaacttcatctcattttagattatataaatggtggtgaacttttt
actcatctttctcaaagagagcgtttcacagagcatgaggtgcagatttatgttggagag
attgtgcttgccctcgaacatctccacaagttggggattatatatcgtgatattaagctt
gagaatattctacttgattctaatggccatgtggtgctgacagattttggtctgagtaag
gagtttgtggctgatgaaactgaaagagcatattccttttgtggaactattgaatacatg
gcaccagatattgtcagagggggagattcaggacatgacaaggcagttgactggtggagt
ttgggtgttctaatgtatgaattactaactggagcatctcctttcactgttgatggagaa
aaaaattcccaagctgagatatctaggagaatattaaaaagtgagcctccatatccccaa
gaaatgagtgctttagcgaaagacctaattcagcgtcttttgatgaaagatcccaagaag
agattgggatgtggtccacgtgatgcagatgaaatcaaagaacatctcttctttcagaaa
ataaattgggatgatttagccgccaaaaaagtgcctgcaccatttaagccagtcattcga
gatgaattagatgtgagtaactttgcagaagagttcacagaaatggatcccacttattct
cccgcagccctgccccagagttctgagaagctgtttcagggctattcctttgttgctcct
tccatcctattcaagcgtaatgcagctgtcatagaccctcttcagtttcacatgggagtt
gaacgtcctggagtgacaaatgttgccaggagtgcaatgatgaaggactctccattctat
caacactatgacctagatttgaaggacaaacccctgggagaaggtagtttttcaatttgt
cgaaagtgtgtgcataaaaaaagtaaccaagcttttgcagtcaaaataatcagcaaaagg
atggaagccaatactcaaaaggaaataacagctctgaaactctgtgaaggacaccccaat
attgtgaagttgcatgaagtttttcatgatcagcttcacacgtttctagtgatggaactt
ctgaatggaggagaactgtttgagcgcattaagaaaaagaagcacttcagtgagacggaa
gccagctacatcatgaggaagcttgtttcagctgtaagccacatgcatgatgttggagtg
gtgcacagggatctgaaacctgagaatttattgttcaccgatgaaaatgacaatttggaa
attaaaataattgattttggatttgcacggctaaagccaccggataatcagcccctgaag
actccatgcttcacccttcattatgccgccccagagctcttgaatcagaacggctacgat
gagtcctgtgacctgtggagcttgggcgtcattttgtacacaatgttgtcaggacaggtt
cccttccaatctcatgaccgaagtttgacgtgtaccagcgcggtggaaatcatgaagaaa
attaaaaagggagatttctcctttgaaggagaagcctggaagaatgtatcccaagaggct
aaagatttgatccaaggacttctcacagtagatccaaacaaaaggcttaaaatgtctggc
ttgaggtacaatgaatggctacaagatggaagtcagctgtcctccaatcctctgatgact
ccggatattctaggatcttccggagctgccgtgcatacctgtgtgaaagcaaccttccac
gcctttaacaaatacaagagagaggggttttgccttcagaatgttgataaggcccctttg
gctaagagaagaaaaatgaaaaagactagcaccagtaccgagacgcgcagcagttccagt
gagagttcccattcttcttcctctcattctcacggtaaaactacacccaccaagacactg
cagcccagcaatcctgccgacagcaataacccggagaccctcttccagttctcggactca
gtagcttag

All links

Pathway (4)   
   KEGG PATHWAY (4)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (15)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (7)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (4)   
   UniProt (2)   
   RefSeq(pep) (2)   
DNA sequence (20)   
   RefSeq(nuc) (2)   
   GenBank (9)   
   EMBL (9)   
3D Structure (3)   
   PDB (3)   
Protein domain (9)   
   Pfam (9)   
All databases (58)   

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