KEGG T01001: 9253

Homo sapiens (human): 9253

Entry

9253 CDS T01001

Gene name

NUMBL, CAG3A, CTG3a, NBL, NUMB-R, NUMBLIKE, NUMBR, TNRC23

Definition

numb homolog (Drosophila)-like

Orthology

K06057

numb

Organism

hsa Homo sapiens (human)

Pathway

hsa04330

Notch signaling pathway

Class

Environmental Information Processing; Signal transduction; Notch signaling pathway [PATH:hsa04330]

SSDB

Motif

Pfam:

NumbF PID PTB PID_2 Spt20 Suf

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

UniProt:

Structure

PDB:

3F0W

Position

19q13.13-q13.2

AA seq 609 aa
MSRSAAASGGPRRPERHLPPAPCGAPGPPETCRTEPDGAGTMNKLRQSLRRRKPAYVPEA
SRPHQWQADEDAVRKGTCSFPVRYLGHVEVEESRGMHVCEDAVKKLKAMGRKSVKSVLWV
SADGLRVVDDKTKDLLVDQTIEKVSFCAPDRNLDKAFSYICRDGTTRRWICHCFLALKDS
GERLSHAVGCAFAACLERKQRREKECGVTAAFDASRTSFAREGSFRLSGGGRPAEREAPD
KKKAEAAAAPTVAPGPAQPGHVSPTPATTSPGEKGEAGTPVAAGTTAAAIPRRHAPLEQL
VRQGSFRGFPALSQKNSPFKRQLSLRLNELPSTLQRRTDFQVKGTVPEMEPPGAGDSDSI
NALCTQISSSFASAGAPAPGPPPATTGTSAWGEPSVPPAAAFQPGHKRTPSEAERWLEEV
SQVAKAQQQQQQQQQQQQQQQQQQQQAASVAPVPTMPPALQPFPAPVGPFDAAPAQVAVF
LPPPHMQPPFVPAYPGLGYPPMPRVPVVGITPSQMVANAFCSAAQLQPQPATLLGKAGAF
PPPAIPSAPGSQARPRPNGAPWPPEPAPAPAPELDPFEAQWAALEGKATVEKPSNPFSGD
LQKTFEIEL

NT seq 1830 nt +upstreamnt +downstreamnt
atgtcccgcagcgcggcggccagcggcggaccccggaggcctgagcggcacctgccccca
gccccctgtggggccccggggcccccagaaacctgcaggacggagccagacggggcgggc
accatgaacaagttacggcagagcctgcggcggaggaagccagcctacgtgcccgaggcg
tcgcgcccgcaccagtggcaggcagacgaggacgcggtgcggaagggcacgtgcagcttc
ccggtcaggtacctgggtcacgtggaggtagaggagtcccggggaatgcacgtgtgtgaa
gatgcggtgaagaagctgaaggcgatgggccgaaagtccgtgaagtctgtcctgtgggtg
tcagccgatgggctccgagtggtggacgacaaaaccaaggatcttctggtcgaccagacc
atcgaaaaggtctccttttgtgctcctgaccgcaacctggacaaggctttctcctatatc
tgtcgtgacgggactacccgccgctggatctgccactgttttctggcactgaaggactcc
ggcgagaggctgagccacgctgtgggctgtgcttttgccgcctgcctggagcgaaaacag
cgacgggagaaggaatgtggggtcacggccgccttcgatgccagccgcaccagcttcgcc
cgcgagggctccttccgcctgtctgggggtgggcggcctgctgagcgagaggccccggac
aagaagaaagcagaggcagcagctgcccccactgtggctcctggccctgcccagcctggg
cacgtgtccccgacaccagccaccacatcccctggtgagaagggtgaggcaggcacccct
gtggctgcaggcaccactgcggccgccatcccccggcgccatgcacccctggagcagctg
gttcgccagggctccttccgtgggttcccagcactcagccagaagaactcgcctttcaaa
cggcagctgagcctacggctgaatgagctgccatccacgctgcagcgccgcactgacttc
caggtgaagggcacagtgcctgagatggagcctcctggtgccggcgacagtgacagcatc
aacgctctgtgcacacagatcagttcatcttttgccagtgctggagcgccagcaccaggg
ccaccacctgccacaacagggacttctgcctggggtgagccctccgtgccccctgcagct
gccttccagcctgggcacaagcggacaccttcagaggctgagcgatggctggaggaggtg
tcacaggtggccaaggcccagcagcagcagcagcagcaacagcaacagcagcagcagcag
cagcagcaacagcagcaagcagcctcagtggccccagtgcccaccatgcctcctgccctg
cagcctttccccgcccccgtggggccctttgacgctgcacctgcccaagtggccgtgttc
ctgccacccccacacatgcagcccccttttgtgcccgcctacccgggcttgggctaccca
ccgatgccccgggtgcccgtggtgggcatcacaccctcacagatggtggcaaacgccttc
tgctcagccgcccagctccagcctcagcctgccactctgcttgggaaagctggggccttc
ccgccccctgccatacccagtgcccctgggagccaggcccgccctcgccccaatggggcc
ccctggccccctgagccagcgcctgccccagctccagagttggacccctttgaggcccag
tgggcggcattagaaggcaaagccactgtagagaaaccctccaaccccttttctggcgac
ctgcaaaagacattcgagattgaactgtag

All links

Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (13)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (7)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (21)   
   RefSeq(nuc) (1)   
   GenBank (10)   
   EMBL (10)   
3D Structure (1)   
   PDB (1)   
Protein domain (6)   
   Pfam (6)   
All databases (46)   

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