KEGG   Homo sapiens (human): 9378Help
Entry
9378              CDS       T01001                                 

Gene name
NRXN1, Hs.22998, PTHSL2, SCZD17
Definition
(RefSeq) neurexin 1
  KO
K07377  
neurexin
Organism
hsa  Homo sapiens (human)
Pathway
Cell adhesion molecules (CAMs)
Disease
H00756  
Pitt-Hopkins syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signaling molecules and interaction
   04514 Cell adhesion molecules (CAMs)
    9378 (NRXN1)
Cell adhesion molecules and their ligands [BR:hsa04516]
 7. Others
  NLGN; neuroligin [KO:K07378]
   9378 (NRXN1)
  DAG1; dystroglycan 1 [KO:K06265]
   9378 (NRXN1)
  LRRTM1_2; leucine-rich repeat transmembrane neuronal protein 1/2 [KO:K16665]
   9378 (NRXN1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-ProteinID: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Structure
PDB: 

Jmol
Position
2p16.3
AA seq 1477 aa AA seqDB search
MGTALLQRGGCFLLCLSLLLLGCWAELGSGLEFPGAEGQWTRFPKWNACCESEMSFQLKT
RSARGLVLYFDDEGFCDFLELILTRGGRLQLSFSIFCAEPATLLADTPVNDGAWHSVRIR
RQFRNTTLFIDQVEAKWVEVKSKRRDMTVFSGLFVGGLPPELRAAALKLTLASVREREPF
KGWIRDVRVNSSQVLPVDSGEVKLDDEPPNSGGGSPCEAGEEGEGGVCLNGGVCSVVDDQ
AVCDCSRTGFRGKDCSQEDNNVEGLAHLMMGDQGKSKGKEEYIATFKGSEYFCYDLSQNP
IQSSSDEITLSFKTLQRNGLMLHTGKSADYVNLALKNGAVSLVINLGSGAFEALVEPVNG
KFNDNAWHDVKVTRNLRQHSGIGHAMVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSP
STADLPGSPVSNNFMGCLKEVVYKNNDVRLELSRLAKQGDPKMKIHGVVAFKCENVATLD
PITFETPESFISLPKWNAKKTGSISFDFRTTEPNGLILFSHGKPRHQKDAKHPQMIKVDF
FAIEMLDGHLYLLLDMGSGTIKIKALLKKVNDGEWYHVDFQRDGRSGTISVNTLRTPYTA
PGESEILDLDDELYLGGLPENKAGLVFPTEVWTALLNYGYVGCIRDLFIDGQSKDIRQMA
EVQSTAGVKPSCSKETAKPCLSNPCKNNGMCRDGWNRYVCDCSGTGYLGRSCEREATVLS
YDGSMFMKIQLPVVMHTEAEDVSLRFRSQRAYGILMATTSRDSADTLRLELDAGRVKLTV
NLDCIRINCNSSKGPETLFAGYNLNDNEWHTVRVVRRGKSLKLTVDDQQAMTGQMAGDHT
RLEFHNIETGIITERRYLSSVPSNFIGHLQSLTFNGMAYIDLCKNGDIDYCELNARFGFR
NIIADPVTFKTKSSYVALATLQAYTSMHLFFQFKTTSLDGLILYNSGDGNDFIVVELVKG
YLHYVFDLGNGANLIKGSSNKPLNDNQWHNVMISRDTSNLHTVKIDTKITTQITAGARNL
DLKSDLYIGGVAKETYKSLPKLVHAKEGFQGCLASVDLNGRLPDLISDALFCNGQIERGC
EGPSTTCQEDSCSNQGVCLQQWDGFSCDCSMTSFSGPLCNDPGTTYIFSKGGGQITYKWP
PNDRPSTRADRLAIGFSTVQKEAVLVRVDSSSGLGDYLELHIHQGKIGVKFNVGTDDIAI
EESNAIINDGKYHVVRFTRSGGNATLQVDSWPVIERYPAGRQLTIFNSQATIIIGGKEQG
QPFQGQLSGLYYNGLKVLNMAAENDANIAIVGNVRLVGEVPSSMTTESTATAMQSEMSTS
IMETTTTLATSTARRGKPPTKEPISQTTDDILVASAECPSDDEDIDPCEPSSGGLANPTR
AGGREPYPGSAEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYHVDESRN
YISNSAQSNGAVVKEKQPSSAKSSNKNKKNKDKEYYV
NT seq 4434 nt NT seq  +upstreamnt  +downstreamnt
atggggacggcgctgctccagcgcgggggctgttttcttctgtgcctctcgctgctgctc
ctgggctgctgggcggagctgggcagcgggctggagtttccgggcgccgagggccaatgg
acgcgcttccccaagtggaacgcctgctgcgagagcgagatgagcttccagctcaagact
cgcagcgcccgcggcctcgtgctctacttcgacgacgagggcttctgcgacttcctggag
ctgattctgacgcgcggcggccgcctgcagctcagcttctccatcttctgcgctgagcct
gcgacgctcctggccgacacgccggttaacgacggcgcctggcacagcgtgcgcatccgc
cgccagttccgcaacaccacgctcttcatcgaccaggtggaggccaagtgggtggaggtc
aagtccaagcgcagggacatgacggtgttcagcggccttttcgtcggggggctgcccccg
gaactgcgcgccgcggcgctcaagctcaccctggcctcggtgagggagcgggagcccttc
aaggggtggattcgtgacgtgagggtcaactcctcgcaggtcctgcccgtggacagcggc
gaggtgaagctggacgatgagccgcccaacagcggcgggggaagcccgtgcgaggcgggc
gaggagggcgagggcggggtgtgcctcaacggaggtgtgtgctccgtggtggacgaccag
gccgtgtgcgactgctcgcgaaccggcttccgcggcaaggactgcagccaagaagacaac
aatgtggaaggtctggcgcacctgatgatgggcgaccaaggtaaaagtaaaggaaaagaa
gaatatattgccacgttcaaaggatctgaatacttctgctacgacttgtctcaaaacccc
attcaaagcagcagtgatgaaataactctgtcatttaaaacccttcagaggaatggactg
atgcttcacactgggaaatcggctgattatgtcaatcttgccctgaaaaatggagctgtc
tctctggtcattaatttgggatcaggggcctttgaagcactagtggagcctgtgaatgga
aagtttaatgataatgcctggcatgatgtgaaagtcaccaggaatctgcgtcagcactca
ggcattggacacgctatggtgacaatatcagtggatgggattcttaccacaacgggctac
acgcaagaagattataccatgctggggtctgatgactttttctatgttggaggcagtccc
agcacagccgaccttccagggtcaccagtcagtaacaactttatgggctgtctcaaagag
gttgtatataaaaataatgatgtgaggctggaattatctcgacttgccaagcaaggagat
cctaagatgaagatccatggagtggtggcatttaaatgtgagaatgttgcaactttagac
ccaatcacctttgaaaccccagagtctttcatctctttgcctaaatggaatgcaaagaaa
actggctccatatcatttgatttccgtacaacagagccaaatggcctcatcttatttagc
catggcaagccaagacatcagaaagatgccaagcacccacagatgataaaggtggacttc
tttgctattgagatgctagatggccacctctacctcctcctggacatggggtcaggtact
ataaaaataaaagccctgttgaagaaagtgaatgatggagaatggtatcatgtggacttc
cagagagacggacggtcaggtaccatttctgtcaacacgttgcgtactccctacactgct
cctggtgagagtgagattctggacctggatgatgagttgtacctgggggggctgccagaa
aataaagctggccttgtcttccccaccgaggtgtggactgctctgctcaactatggctac
gtgggctgcatcagggatttgttcatcgatggccaaagcaaagatatccggcaaatggct
gaagttcaaagtactgctggagtgaagccttcctgctcaaaggaaacagcaaaaccgtgc
cttagcaacccttgcaaaaacaatggcatgtgcagggatgggtggaacagatatgtctgt
gattgttccggaacaggctatcttggcaggtcctgtgagagagaggcaacggttttgagc
tatgatgggagcatgtttatgaaaattcagctccccgtagtcatgcatacggaggctgag
gatgtttccttacggttccgatcccagcgtgcatatggcattctgatggcaaccacttct
agagactctgctgacaccctccgcctggagctagacgcaggacgtgtgaaactgacggtc
aatctagattgtatcaggattaactgtaattccagcaaaggtcccgagactctttttgct
ggctataacctcaatgataacgagtggcacacagtgcgtgtagttcggcgtggaaaaagt
ttaaagttaacagtggatgaccaacaggccatgacaggtcaaatggcaggtgatcatact
aggctggagttccataacatagagactggcatcatcacagaacgacggtatctttcttct
gtcccctccaacttcattggacacctgcagagcttgacatttaatggaatggcatacatt
gacctgtgtaaaaatggcgacatagattactgtgagcttaatgccagatttggcttcagg
aacatcatagcagatcctgtcaccttcaagaccaaatcgagctatgttgccttagctacc
ttgcaagcctacacttctatgcatctttttttccagttcaagacaacatccctagatgga
ttaattctatataacagtggggatggaaatgactttattgtggttgaattagttaaaggg
tacttacattacgtgtttgatttgggaaatggtgctaacctcatcaaaggaagctcaaat
aaacctctcaatgacaatcagtggcacaacgtgatgatatcaagggacaccagcaacctc
cacactgtaaagattgacacaaaaatcacaacgcaaatcaccgccggagccaggaactta
gacctcaagagtgacttatatataggaggagtagctaaagaaacatacaaatccttacca
aaacttgtacatgccaaagaaggctttcaaggctgcctggcatcagttgatttaaatgga
cggcttccggacctcatctccgatgctcttttctgcaacggacagatcgagagaggatgt
gaagggcccagcacaacctgccaagaggactcatgttccaatcaaggtgtgtgcttgcaa
caatgggatggcttcagctgtgactgtagtatgacttccttcagtggaccactctgcaat
gaccctgggacgacatatatctttagcaaaggtggtggacaaatcacgtataagtggcct
cctaatgaccgacccagtacacgagcagacagactggccataggttttagcactgttcag
aaagaagccgtattggtgcgagtggacagttcttcaggcttgggtgactacctagaactg
catatacaccagggaaaaattggagttaagtttaatgttgggacagatgacatcgccatt
gaagaatccaatgcaatcattaatgatgggaaataccatgtagttcgtttcacgaggagt
ggtggcaatgccacgttgcaggtggacagctggccagtgatcgagcgctaccctgcaggg
cgtcagctcacaatcttcaatagccaagcaaccataataattggcgggaaagagcagggc
cagcccttccagggccagctctctgggctgtactacaatggcttgaaagttctgaatatg
gcagccgaaaacgatgccaacatcgccatagtgggaaatgtgagactggttggtgaagtg
ccttcctctatgacaactgagtcaacagccactgccatgcaatcagagatgtccacatca
attatggagactaccacgaccctggctactagcacagccagaagaggaaagcccccgaca
aaagaacccattagccagaccacagatgacatccttgtggcctcagcagagtgtcccagc
gatgatgaggacattgacccctgtgagccgagctcaggtgggttagccaacccaacccga
gcaggcggcagagagccgtatccaggctcagcagaagtgatccgggagtccagcagcacc
acgggtatggtcgttgggatagtagccgctgccgccctgtgcatccttatcctcctctat
gccatgtacaagtacagaaaccgggatgaaggctcataccatgtggacgagagtcgaaac
tacatcagtaactcagcacagtccaatggggctgttgtaaaggagaaacaacccagcagt
gcgaaaagctccaacaaaaataagaaaaacaaggataaagagtattatgtctga

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