KEGG   Homo sapiens (human): 9448Help
Entry
9448              CDS       T01001                                 

Gene name
MAP4K4, FLH21957, HEL-S-31, HGK, MEKKK4, NIK
Definition
mitogen-activated protein kinase kinase kinase kinase 4 (EC:2.7.11.1)
Orthology
K04407  
mitogen-activated protein kinase kinase kinase kinase 4 [EC:2.7.11.1]
Organism
hsa  Homo sapiens (human)
Pathway
MAPK signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    9448 (MAP4K4)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     9448 (MAP4K4)
Protein kinases [BR:hsa01001]
 Serine/threonine protein kinases: STE group
  STE20 family
   9448 (MAP4K4)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Position
2q11.2-q12
AA seq 1239 aa AA seqDB search
MANDSPAKSLVDIDLSSLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTE
DEEEEIKLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNT
KGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
TVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPLCDMHPMR
ALFLIPRNPPPRLKSKKWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFIRDQPNERQVRI
QLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQ
QENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREAR
RQQEREQRRREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLE
VLQQQLLQEQAMLLECRWREMEEHRQAERLQRQLQQEQAYLLSLQHDHRRPHPQHSQQPP
PPQQERSKPSFHAPEPKAHYEPADRAREVEDRFRKTNHSSPEAQSKQTGRVLEPPVPSRS
ESFSNGNSESVHPALQRPAEPQVPVRTTSRSPVLSRRDSPLQGSGQQNSQAGQRNSTSIE
PRLLWERVEKLVPRPGSGSSSGSSNSGSQPGSHPGSQSGSGERFRVRSSSKSEGSPSQRL
ENAVKKPEDKKEVFRPLKPADLTALAKELRAVEDVRPPHKVTDYSSSSEESGTTDEEDDD
VEQEGADESTSGPEDTRAASSLNLSNGETESVKTMIVHDDVESEPAMTPSKEGTLIVRQT
QSASSTLQKHKSSSSFTPFIDPRLLQISPSSGTTVTSVVGFSCDGMRPEAIRQDPTRKGS
VVNVNPTNTRPQSDTPEIRKYKKRFNSEILCAALWGVNLLVGTESGLMLLDRSGQGKVYP
LINRRRFQQMDVLEGLNVLVTISGKKDKLRVYYLSWLRNKILHNDPEVEKKQGWTTVGDL
EGCVHYKVVKYERIKFLVIALKSSVEVYAWAPKPYHKFMAFKSFGELVHKPLLVDLTVEE
GQRLKVIYGSCAGFHAVDVDSGSVYDIYLPTHIQCSIKPHAIIILPNTDGMELLVCYEDE
GVYVNTYGRITKDVVLQWGEMPTSVAYIRSNQTMGWGEKAIEIRSVETGHLDGVFMHKRA
QRLKFLCERNDKVFFASVRSGGSSQVYFMTLGRTSLLSW
NT seq 3720 nt NT seq  +upstreamnt  +downstreamnt
atggcgaacgactcccctgcaaaaagtctggtggacatcgacctctcctccctgcgggat
cctgctgggatttttgagctggtggaagtggttggaaatggcacctatggacaagtctat
aagggtcgacatgttaaaacgggtcagttggcagccatcaaagttatggatgtcactgag
gatgaagaggaagaaatcaaactggagataaatatgctaaagaaatactctcatcacaga
aacattgcaacatattatggtgctttcatcaaaaagagccctccaggacatgatgaccaa
ctctggcttgttatggagttctgtggggctgggtccattacagaccttgtgaagaacacc
aaagggaacacactcaaagaagactggatcgcttacatctccagagaaatcctgagggga
ctggcacatcttcacattcatcatgtgattcaccgggatatcaagggccagaatgtgttg
ctgactgagaatgcagaggtgaaacttgttgactttggtgtgagtgctcagctggacagg
actgtggggcggagaaatacgttcataggcactccctactggatggctcctgaggtcatc
gcctgtgatgagaacccagatgccacctatgattacagaagtgatctttggtcttgtggc
attacagccattgagatggcagaaggtgctccccctctctgtgacatgcatccaatgaga
gcactgtttctcattcccagaaaccctcctccccggctgaagtcaaaaaaatggtcgaag
aagttttttagttttatagaagggtgcctggtgaagaattacatgcagcggccctctaca
gagcagcttttgaaacatccttttataagggatcagccaaatgaaaggcaagttagaatc
cagcttaaggatcatatagatcgtaccaggaagaagagaggcgagaaagatgaaactgag
tatgagtacagtgggagtgaggaagaagaggaggaagtgcctgaacaggaaggagagcca
agttccattgtgaacgtgcctggtgagtctactcttcgccgagatttcctgagactgcag
caggagaacaaggaacgttccgaggctcttcggagacaacagttactacaggagcaacag
ctccgggagcaggaagaatataaaaggcaactgctggcagagagacagaagcggattgag
cagcagaaagaacagaggcgacggctagaagagcaacaaaggagagagcgggaagctaga
aggcagcaggaacgtgaacagcgaaggagagaacaagaagaaaagaggcgtctagaggag
ttggagagaaggcgcaaagaagaagaggagaggagacgggcagaagaagaaaagaggaga
gttgaaagagaacaggagtatatcaggcgacagctagaagaggagcagcggcacttggaa
gtccttcagcagcagctgctccaggagcaggccatgttactggagtgccgatggcgggag
atggaggagcaccggcaggcagagaggctccagaggcagttgcaacaagaacaagcatat
ctcctgtctctacagcatgaccataggaggccgcacccgcagcactcgcagcagccgcca
ccaccgcagcaggaaaggagcaagccaagcttccatgctcccgagcccaaagcccactac
gagcctgctgaccgagcgcgagaggtggaagatagatttaggaaaactaaccacagctcc
cctgaagcccagtctaagcagacaggcagagtattggagccaccagtgccttcccgatca
gagtctttttccaatggcaactccgagtctgtgcatcccgccctgcagagaccagcggag
ccacaggttcctgtgagaacaacatctcgctcccctgttctgtcccgtcgagattcccca
ctgcagggcagtgggcagcagaatagccaggcaggacagagaaactccaccagtattgag
cccaggcttctgtgggagagagtggagaagctggtgcccagacctggcagtggcagctcc
tcagggtccagcaactcaggatcccagcccgggtctcaccctgggtctcagagtggctcc
ggggaacgcttcagagtgagatcatcatccaagtctgaaggctctccatctcagcgcctg
gaaaatgcagtgaaaaaacctgaagataaaaaggaagttttcagacccctcaagcctgct
gatctgaccgcactggccaaagagcttcgagcagtggaagatgtacggccacctcacaaa
gtaacggactactcctcatccagtgaggagtcggggacgacggatgaggaggacgacgat
gtggagcaggaaggggctgacgagtccacctcaggaccagaggacaccagagcagcgtca
tctctgaatttgagcaatggtgaaacggaatctgtgaaaaccatgattgtccatgatgat
gtagaaagtgagccggccatgaccccatccaaggagggcactctaatcgtccgccagact
cagtccgctagtagcacactccagaaacacaaatcttcctcctcctttacaccttttata
gaccccagattactacagatttctccatctagcggaacaacagtgacatctgtggtggga
ttttcctgtgatgggatgagaccagaagccataaggcaagatcctacccggaaaggctca
gtggtcaatgtgaatcctaccaacactaggccacagagtgacaccccggagattcgtaaa
tacaagaagaggtttaactctgagattctgtgtgctgccttatggggagtgaatttgcta
gtgggtacagagagtggcctgatgctgctggacagaagtggccaagggaaggtctatcct
cttatcaaccgaagacgatttcaacaaatggacgtacttgagggcttgaatgtcttggtg
acaatatctggcaaaaaggataagttacgtgtctactatttgtcctggttaagaaataaa
atacttcacaatgatccagaagttgagaagaagcagggatggacaaccgtaggggatttg
gaaggatgtgtacattataaagttgtaaaatatgaaagaatcaaatttctggtgattgct
ttgaagagttctgtggaagtctatgcgtgggcaccaaagccatatcacaaatttatggcc
tttaagtcatttggagaattggtacataagccattactggtggatctcactgttgaggaa
ggccagaggttgaaagtgatctatggatcctgtgctggattccatgctgttgatgtggat
tcaggatcagtctatgacatttatctaccaacacatatccagtgtagcatcaaaccccat
gcaatcatcatcctccccaatacagatggaatggagcttctggtgtgctatgaagatgag
ggggtttatgtaaacacatatggaaggatcaccaaggatgtagttctacagtggggagag
atgcctacatcagtagcatatattcgatccaatcagacaatgggctggggagagaaggcc
atagagatccgatctgtggaaactggtcacttggatggtgtgttcatgcacaaaagggct
caaagactaaaattcttgtgtgaacgcaatgacaaggtgttctttgcctctgttcggtct
ggtggcagcagtcaggtttatttcatgaccttaggcaggacttctcttctgagctggtag

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