KEGG T01001: 9612

Homo sapiens (human): 9612

Entry

9612 CDS T01001

Gene name

NCOR2, CTG26, N-CoR2, SMAP270, SMRT, SMRTE, SMRTE-tau, TNRC14, TRAC, TRAC-1, TRAC1

Definition

nuclear receptor corepressor 2

Orthology

K06065

nuclear receptor co-repressor 2

Organism

hsa Homo sapiens (human)

Pathway

hsa04330	Notch signaling pathway
hsa05169	Epstein-Barr virus infection

Class

Environmental Information Processing; Signal transduction; Notch signaling pathway [PATH:hsa04330]
Human Diseases; Infectious diseases; Epstein-Barr virus infection [PATH:hsa05169]

SSDB

Motif

Pfam:

Myb_DNA-binding Myb_DNA-bind_6

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

Q9Y618 C9J0Q5 C9JE98 C9JFD3

Structure

PDB:

4A69 2LTP 2L5G 1XC5

Position

12q24

AA seq 2458 aa
MSGSTQPVAQTWRATEPRYPPHSLSYPVQIARTHTDVGLLEYQHHSRDYASHLSPGSIIQ
PQRRRPSLLSEFQPGNERSQELHLRPESHSYLPELGKSEMEFIESKRPRLELLPDPLLRP
SPLLATGQPAGSEDLTKDRSLTGKLEPVSPPSPPHTDPELELVPPRLSKEELIQNMDRVD
REITMVEQQISKLKKKQQQLEEEAAKPPEPEKPVSPPPIESKHRSLVQIIYDENRKKAEA
AHRILEGLGPQVELPLYNQPSDTRQYHENIKINQAMRKKLILYFKRRNHARKQWEQKFCQ
RYDQLMEAWEKKVERIENNPRRRAKESKVREYYEKQFPEIRKQRELQERMQRVGQRGSGL
SMSAARSEHEVSEIIDGLSEQENLEKQMRQLAVIPPMLYDADQQRIKFINMNGLMADPMK
VYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKS
LVRRSYRRRGKSQQQQQQQQQQQQQQQQQPMPRSSQEEKDEKEKEKEAEKEEEKPEVEND
KEDLLKEKTDDTSGEDNDEKEAVASKGRKTANSQGRRKGRITRSMANEANSEEAITPQQS
AELASMELNESSRWTEEEMETAKKGLLEHGRNWSAIARMVGSKTVSQCKNFYFNYKKRQN
LDEILQQHKLKMEKERNARRKKKKAPAAASEEAAFPPVVEDEEMEASGVSGNEEEMVEEA
EATVNNSSDTESIPSPHTEAAKDTGQNGPKPPATLGADGPPPGPPTPPPEDIPAPTEPTP
ASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETAAAPPVEEGEEQKPPAAEELAVDTGKA
EEPVKSECTEEAEEGPAKGKDAEAAEATAEGALKAEKKEGGSGRATTAKSSGAPQDSDSS
ATCSADEVDEAEGGDKNRLLSPRPSLLTPTGDPRANASPQKPLDLKQLKQRAAAIPPIQV
TKVHEPPREDAAPTKPAPPAPPPPQNLQPESDAPQQPGSSPRGKSRSPAPPADKEAEKPV
FFPAFAAEAQKLPGDPPCWTSGLPFPVPPREVIKASPHAPDPSAFSYAPPGHPLPLGLHD
TARPVLPRPPTISNPPPLISSAKHPSVLERQIGAISQGMSVQLHVPYSEHAKAPVGPVTM
GLPLPMDPKKLAPFSGVKQEQLSPRGQAGPPESLGVPTAQEASVLRGTALGSVPGGSITK
GIPSTRVPSDSAITYRGSITHGTPADVLYKGTITRIIGEDSPSRLDRGREDSLPKGHVIY
EGKKGHVLSYEGGMSVTQCSKEDGRSSSGPPHETAAPKRTYDMMEGRVGRAISSASIEGL
MGRAIPPERHSPHHLKEQHHIRGSITQGIPRSYVEAQEDYLRREAKLLKREGTPPPPPPS
RDLTEAYKTQALGPLKLKPAHEGLVATVKEAGRSIHEIPREELRHTPELPLAPRPLKEGS
ITQGTPLKYDTGASTTGSKKHDVRSLIGSPGRTFPPVHPLDVMADARALERACYEESLKS
RPGTASSSGGSIARGAPVIVPELGKPRQSPLTYEDHGAPFAGHLPRGSPVTTREPTPRLQ
EGSLSSSKASQDRKLTSTPREIAKSPHSTVPEHHPHPISPYEHLLRGVSGVDLYRSHIPL
AFDPTSIPRGIPLDAAAAYYLPRHLAPNPTYPHLYPPYLIRGYPDTAALENRQTIINDYI
TSQQMHHNAATAMAQRADMLRGLSPRESSLALNYAAGPRGIIDLSQVPHLPVLVPPTPGT
PATAMDRLAYLPTAPQPFSSRHSSSPLSPGGPTHLTKPTTTSSSERERDRDRERDRDRER
EKSILTSTTTVEHAPIWRPGTEQSSGSSGGGGGSSSRPASHSHAHQHSPISPRTQDALQQ
RPSVLHNTGMKGIITAVEPSTPTVLRSTSTSSPVRPAATFPPATHCPLGGTLDGVYPTLM
EPVLLPKEAPRVARPERPRADTGHAFLAKPPARSGLEPASSPSKGSEPRPLVPPVSGHAT
IARTPAKNLAPHHASPDPPAPPASASDPHREKTQSKPFSIQELELRSLGYHGSSYSPEGV
EPVSPVSSPSLTHDKGLPKHLEELDKSHLEGELRPKQPGPVKLGGEAAHLPHLRPLPESQ
PSSSPLLQTAPGVKGHQRVVTLAQHISEVITQDYTRHHPQQLSAPLPAPLYSFPGASCPV
LDLRRPPSDLYLPPPDHGAPARGSPHSEGGKRSPEPNKTSVLGGGEDGIEPVSPPEGMTE
PGHSRSAVYPLLYRDGEQTEPSRMGSKSPGNTSQPPAFFSKLTESNSAMVKSKKQEINKK
LNTHNRNEPEYNISQPGTEIFNMPAITGTGLMTYRSQAVQEHASTNMGLEAIIRKALMGG
GGKAKVSGRPSSRKAKSPAPGLASGDRPPSVSSVHSEGDCNRRTPLTNRVWEDRPSSAGS
TPFPYNPLIMRLQAGVMASPPPPGLPAGSGPLAGPHHAWDEEPKPLLCSQYETLSDSE

NT seq 7377 nt +upstreamnt +downstreamnt
atgtcgggatccacacagcctgtggcacagacgtggagggccactgagccccgctacccg
ccccacagcctttcctacccagtgcagatcgcccggacgcacacggacgtcgggctcctg
gagtaccagcaccactcccgcgactatgcctcccacctgtcgcccggctccatcatccag
ccccagcggcggaggccctccctgctgtctgagttccagcccgggaatgaacggtcccag
gagctccacctgcggccagagtcccactcatacctgcccgagctggggaagtcagagatg
gagttcattgaaagcaagcgccctcggctagagctgctgcctgaccccctgctgcgaccg
tcacccctgctggccacgggccagcctgcgggatctgaagacctcaccaaggaccgtagc
ctgacgggcaagctggaaccggtgtctccccccagccccccgcacactgaccctgagctg
gagctggtgccgccacggctgtccaaggaggagctgatccagaacatggaccgcgtggac
cgagagatcaccatggtagagcagcagatctctaagctgaagaagaagcagcaacagctg
gaggaggaggctgccaagccgcccgagcctgagaagcccgtgtcaccgccgcccatcgag
tcgaagcaccgcagcctggtgcagatcatctacgacgagaaccggaagaaggctgaagct
gcacatcggattctggaaggcctggggccccaggtggagctgccgctgtacaaccagccc
tccgacacccggcagtatcatgagaacatcaaaataaaccaggcgatgcggaagaagcta
atcttgtacttcaagaggaggaatcacgctcggaaacaatgggagcagaagttctgccag
cgctatgaccagctcatggaggcctgggagaagaaggtggagcgcatcgagaacaacccc
cggcggcgggccaaggagagcaaggtgcgcgagtactacgagaagcagttccctgagatc
cgcaagcagcgcgagctgcaggagcgcatgcagagggtgggccagcggggcagtgggctg
tccatgtcggccgcccgcagcgagcacgaggtgtcagagatcatcgatggcctctcagag
caggagaacctggagaagcagatgcgccagctggccgtgatcccgcccatgctgtacgac
gctgaccagcagcgcatcaagttcatcaacatgaacgggcttatggccgaccccatgaag
gtgtacaaagaccgccaggtcatgaacatgtggagtgagcaggagaaggagaccttccgg
gagaagttcatgcagcatcccaagaactttggcctgatcgcatcattcctggagaggaag
acagtggctgagtgcgtcctctattactacctgactaagaagaatgagaactataagagc
ctggtgagacggagctatcggcgccgcggcaagagccagcagcagcaacaacagcagcag
cagcagcagcagcagcagcagcagcagcccatgccccgcagcagccaggaggagaaagat
gagaaggagaaggaaaaggaggcggagaaggaggaggagaagccggaggtggagaacgac
aaggaagacctcctcaaggagaagacagacgacacctcaggggaggacaacgacgagaag
gaggctgtggcctccaaaggccgcaaaactgccaacagccagggaagacgcaaaggccgc
atcacccgctcaatggctaatgaggccaacagcgaggaggccatcaccccccagcagagc
gccgagctggcctccatggagctgaatgagagttctcgctggacagaagaagaaatggaa
acagccaagaaaggtctcctggaacacggccgcaactggtcggccatcgcccggatggtg
ggctccaagactgtgtcgcagtgtaagaacttctacttcaactacaagaagaggcagaac
ctcgatgagatcttgcagcagcacaagctgaagatggagaaggagaggaacgcgcggagg
aagaagaagaaagcgccggcggcggccagcgaggaggctgcattcccgcccgtggtggag
gatgaggagatggaggcgtcgggcgtgagcggaaatgaggaggagatggtggaggaggct
gaagccactgtcaacaacagctcagacaccgagagcatcccctctcctcacactgaggcc
gccaaggacacagggcagaatgggcccaagcccccagccaccctgggcgccgacgggcca
cccccagggccacccaccccaccaccggaggacatcccggcccccactgagcccaccccg
gcctctgaagccaccggagcccctacgcccccaccagcacccccatcgccctctgcacct
cctcctgtggtccccaaggaggagaaggaggaggagaccgcagcagcgcccccagtggag
gagggggaggagcagaagccccccgcggctgaggagctggcagtggacacagggaaggcc
gaggagcccgtcaagagcgagtgcacggaggaagccgaggaggggccggccaagggcaag
gacgcggaggccgctgaggccacggccgagggggcgctcaaggcagagaagaaggagggc
gggagcggcagggccaccacagccaagagctcgggcgccccccaggacagcgactccagt
gctacctgcagtgcagacgaggtggatgaggccgagggcggcgacaagaaccggctgctg
tccccaaggcccagcctcctcaccccgactggcgacccccgggccaatgcctcaccccag
aagccactggacctgaagcagctgaagcagcgagcggctgccatcccccccatccaggtc
accaaagtccatgagcccccccgggaggacgcagctcccaccaagccagctcccccagcc
ccaccgccaccgcaaaacctgcagccggagagcgacgcccctcagcagcctggcagcagc
ccccggggcaagagcaggagcccggcaccccccgccgacaaggaggcagagaagcctgtg
ttcttcccagccttcgcagccgaggcccagaagctgcctggggaccccccttgctggact
tccggcctgcccttccccgtgcccccccgtgaggtgatcaaggcctccccgcatgccccg
gacccctcagccttctcctacgctccacctggtcacccactgcccctgggcctccatgac
actgcccggcccgtcctgccgcgcccacccaccatctccaacccgcctcccctcatctcc
tctgccaagcaccccagcgtcctcgagaggcaaataggtgccatctcccaaggaatgtcg
gtccagctccacgtcccgtactcagagcatgccaaggccccggtgggccctgtcaccatg
gggctgcccctgcccatggaccccaaaaagctggcacccttcagcggagtgaagcaggag
cagctgtccccacggggccaggctgggccaccggagagcctgggggtgcccacagcccag
gaggcgtccgtgctgagagggacagctctgggctcagttccgggcggaagcatcaccaaa
ggcattcccagcacacgggtgccctcggacagcgccatcacataccgcggctccatcacc
cacggcacgccagctgacgtcctgtacaagggcaccatcaccaggatcatcggcgaggac
agcccgagtcgcttggaccgcggccgggaggacagcctgcccaagggccacgtcatctac
gaaggcaagaagggccacgtcttgtcctatgagggtggcatgtctgtgacccagtgctcc
aaggaggacggcagaagcagctcaggacccccccatgagacggccgcccccaagcgcacc
tatgacatgatggagggccgcgtgggcagagccatctcctcagccagcatcgaaggtctc
atgggccgtgccatcccgccggagcgacacagcccccaccacctcaaagagcagcaccac
atccgcgggtccatcacacaagggatccctcggtcctacgtggaggcacaggaggactac
ctgcgtcgggaggccaagctcctaaagcgggagggcacgcctccgcccccaccgccctca
cgggacctgaccgaggcctacaagacgcaggccctgggccccctgaagctgaagccggcc
catgagggcctggtggccacggtgaaggaggcgggccgctccatccatgagatcccgcgc
gaggagctgcggcacacgcccgagctgcccctggccccgcggccgctcaaggagggctcc
atcacgcagggcaccccgctcaagtacgacaccggcgcgtccaccactggctccaaaaag
cacgacgtacgctccctcatcggcagccccggccggacgttcccacccgtgcacccgctg
gatgtgatggccgacgcccgggcactggaacgtgcctgctacgaggagagcctgaagagc
cggccagggaccgccagcagctcggggggctccattgcgcgcggcgccccggtcattgtg
cctgagctgggtaagccgcggcagagccccctgacctatgaggaccacggggcacccttt
gccggccacctcccacgaggttcgcccgtgaccacgcgggagcccacgccgcgcctgcag
gagggcagcctttcgtccagcaaggcatcccaggaccgaaagctgacgtcgacgcctcgt
gagatcgccaagtccccgcacagcaccgtgcccgagcaccacccacaccccatctcgccc
tatgagcacctgcttcggggcgtgagtggcgtggacctgtatcgcagccacatccccctg
gccttcgaccccacctccataccccgcggcatccctctggacgcagccgctgcctactac
ctgccccgacacctggcccccaaccccacctacccgcacctgtacccaccctacctcatc
cgcggctaccccgacacggcggcgctggagaaccggcagaccatcatcaatgactacatc
acctcgcagcagatgcaccacaacgcggccaccgccatggcccagcgagctgatatgctg
aggggcctctcgccccgcgagtcctcgctggcactcaactacgctgcgggtccccgaggc
atcatcgacctgtcccaagtgccacacctgcctgtgctcgtgcccccgacaccaggcacc
ccagccaccgccatggaccgccttgcctacctccccaccgcgccccagcccttcagcagc
cgccacagcagctccccactctccccaggaggtccaacacacttgacaaaaccaaccacc
acgtcctcgtccgagcgggagcgagaccgggatcgagagcgggaccgggatcgggagcgg
gaaaagtccatcctcacgtccaccacgacggtggagcacgcacccatctggagacctggt
acagagcagagcagcggcagcagcggcgggggtgggggcagcagcagccgccccgcctcc
cactcccatgcccaccagcactcgcccatctcccctcggacccaggatgccctccagcag
agacccagtgtgcttcacaacacaggcatgaagggtatcatcaccgctgtggagcccagc
acgcccacggtcctgaggtccacctccacctcctcacccgttcgcccggctgccacattc
ccacctgccacccactgcccactgggcggcaccctcgatggggtctaccctaccctcatg
gagcccgtcttgctgcccaaggaggccccccgggtcgcccggccagagcggccccgagca
gacaccggccatgccttcctcgccaagcccccagcccgctccgggctggagcccgcctcc
tcccccagcaagggctcggagccccggcccctagtgcctcctgtctctggccacgccacc
atcgcccgcacccctgcgaagaacctcgcacctcaccacgccagcccggacccgccggcg
ccacctgcctcggcctcggacccgcaccgggaaaagactcaaagtaaacccttttccatc
caggaactggaactccgttctctgggttaccacggcagcagctacagccccgaaggggtg
gagcccgtcagccctgtgagctcacccagtctgacccacgacaaggggctccccaagcac
ctggaagagctcgacaagagccacctggagggggagctgcggcccaagcagccaggcccc
gtgaagcttggcggggaggccgcccacctcccacacctgcggccgctgcctgagagccag
ccctcgtccagcccgctgctccagaccgccccaggggtcaaaggtcaccagcgggtggtc
accctggcccagcacatcagtgaggtcatcacacaggactacacccggcaccacccacag
cagctcagcgcacccctgcccgcccccctctactccttccctggggccagctgccccgtc
ctggacctccgccgcccacccagtgacctctacctcccgcccccggaccatggtgccccg
gcccgtggctccccccacagcgaagggggcaagaggtctccagagccaaacaagacgtcg
gtcttgggtggtggtgaggacggtattgaacctgtgtccccaccggagggcatgacggag
ccagggcactcccggagtgctgtgtacccgctgctgtaccgggatggggaacagacggag
cccagcaggatgggctccaagtctccaggcaacaccagccagccgccagccttcttcagc
aagctgaccgagagcaactccgccatggtcaagtccaagaagcaagagatcaacaagaag
ctgaacacccacaaccggaatgagcctgaatacaatatcagccagcctgggacggagatc
ttcaatatgcccgccatcaccggaacaggccttatgacctatagaagccaggcggtgcag
gaacatgccagcaccaacatggggctggaggccataattagaaaggcactcatgggtggc
ggcgggaaggccaaggtctctggcagacccagcagccgaaaagccaagtccccggccccg
ggcctggcatctggggaccggccaccctctgtctcctcagtgcactcggagggagactgc
aaccgccggacgccgctcaccaaccgcgtgtgggaggacaggccctcgtccgcaggttcc
acgccattcccctacaaccccctgatcatgcggctgcaggcgggtgtcatggcttcccca
cccccaccgggcctccccgcgggcagcgggcccctcgctggcccccaccacgcctgggac
gaggagcccaagccactgctctgctcgcagtacgagacactctccgacagcgagtga

All links

Pathway (2)   
   KEGG PATHWAY (2)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (16)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (8)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (7)   
   UniProt (4)   
   RefSeq(pep) (3)   
DNA sequence (37)   
   RefSeq(nuc) (3)   
   GenBank (17)   
   EMBL (17)   
3D Structure (4)   
   PDB (4)   
Protein domain (2)   
   Pfam (2)   
All databases (70)   

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