KEGG T01001: 9706

Homo sapiens (human): 9706

Entry

9706 CDS T01001

Gene name

ULK2, ATG1B, Unc51.2

Definition

unc-51-like kinase 2 (C. elegans) (EC:2.7.11.1)

Orthology

K08269

unc51-like kinase [EC:2.7.11.1]

Organism

hsa Homo sapiens (human)

Pathway

hsa04140	Regulation of autophagy
hsa04150	mTOR signaling pathway

Class

Environmental Information Processing; Signal transduction; mTOR signaling pathway [PATH:hsa04150]
Cellular Processes; Transport and catabolism; Regulation of autophagy [PATH:hsa04140]

SSDB

Motif

Pfam:

Pkinase DUF3543 Pkinase_Tyr Kdo RIO1 Kinase-like APH N-glycanase_C

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

Position

17p11.2

AA seq 1036 aa
MEVVGDFEYSKRDLVGHGAFAVVFRGRHRQKTDWEVAIKSINKKNLSKSQILLGKEIKIL
KELQHENIVALYDVQELPNSVFLVMEYCNGGDLADYLQAKGTLSEDTIRVFLHQIAAAMR
ILHSKGIIHRDLKPQNILLSYANRRKSSVSGIRIKIADFGFARYLHSNMMAATLCGSPMY
MAPEVIMSQHYDAKADLWSIGTVIYQCLVGKPPFQANSPQDLRMFYEKNRSLMPSIPRET
SPYLANLLLGLLQRNQKDRMDFEAFFSHPFLEQGPVKKSCPVPVPMYSGSVSGSSCGSSP
SCRFASPPSLPDMQHIQEENLSSPPLGPPNYLQVSKDSASTSSKNSSCDTDDFVLVPHNI
SSDHSCDMPVGTAGRRASNEFLVCGGQCQPTVSPHSETAPIPVPTQIRNYQRIEQNLTST
ASSGTNVHGSPRSAVVRRSNTSPMGFLRPGSCSPVPADTAQTVGRRLSTGSSRPYSPSPL
VGTIPEQFSQCCCGHPQGHDSRSRNSSGSPVPQAQSPQSLLSGARLQSAPTLTDIYQNKQ
KLRKQHSDPVCPSHTGAGYSYSPQPSRPGSLGTSPTKHLGSSPRSSDWFFKTPLPTIIGS
PTKTTAPFKIPKTQASSNLLALVTRHGPAEEQSKDGNEPRECAHCLLVQGSERQRAEQQS
KAVFGRSVSTGKLSDQQGKTPICRHQGSTDSLNTERPMDIAPAGACGGVLAPPAGTAASS
KAVLFTVGSPPHSAAAPTCTHMFLRTRTTSVGPSNSGGSLCAMSGRVCVGSPPGPGFGSS
PPGAEAAPSLRYVPYGASPPSLEGLITFEAPELPEETLMEREHTDTLRHLNVMLMFTECV
LDLTAMRGGNPELCTSAVSLYQIQESVVVDQISQLSKDWGRVEQLVLYMKAAQLLAASLH
LAKAQIKSGKLSPSTAVKQVVKNLNERYKFCITMCKKLTEKLNRFFSDKQRFIDEINSVT
AEKLIYNCAVEMVQSAALDEMFQQTEDIVYRYHKAALLLEGLSRILQDPADIENVHKYKC
SIERRLSALCHSTATV

NT seq 3111 nt +upstreamnt +downstreamnt
atggaggtggtgggtgacttcgagtacagcaagagggatctcgtgggacacggggccttc
gccgtggtcttccgggggcggcaccgccagaaaactgattgggaggtagctattaaaagt
attaataaaaagaacttgtcaaaatcacaaatactgcttggaaaggaaattaaaatctta
aaggaacttcagcatgaaaatattgtagcactctatgatgttcaggaattacccaactct
gtctttttggtgatggagtattgcaatggtggagacctcgcagattatttgcaagcgaaa
gggactctcagtgaagacacgatcagagtgtttctgcatcagattgctgctgccatgcga
atcctgcacagcaaaggaatcatccacagagatctcaaaccacagaacatcttgctgtcc
tatgccaatcgcagaaaatcaagtgtcagtggtattcgcatcaaaatagcggattttggt
tttgctcgttacctacatagtaacatgatggctgcaacactgtgtggatccccgatgtac
atggctcctgaggttattatgtctcaacattatgatgctaaggctgacttgtggagcata
ggaacagtgatataccaatgcctagttggaaaaccaccttttcaggccaatagtcctcaa
gacttaaggatgttttatgaaaaaaacaggagcttaatgcctagtattcccagagaaaca
tcaccttatttggctaatctccttttgggtttgcttcagagaaaccaaaaagatagaatg
gactttgaagcattttttagccatccttttcttgagcaaggtccagtaaaaaaatcttgc
ccagttccagtgcccatgtattctggttctgtctctggaagctcctgtggcagctctcca
tcttgtcgttttgcttctccaccatcccttccagatatgcagcatattcaggaagaaaac
ttatcttccccaccattgggtcctcccaactatctacaagtttccaaagattctgccagt
actagtagcaagaactcttcttgtgacacggatgactttgttttggtgccacacaacatc
tcgtcagaccactcatgtgatatgccagtggggactgctggcagacgtgcttcaaatgaa
ttcttggtgtgtggagggcagtgtcagcctactgtgtcacctcacagcgaaacagcacca
attccagttcctactcaaataaggaattatcagcgcatagagcagaatcttacatctact
gccagctcaggcacaaatgtacatggttctccaagatctgcagtggtacgaaggtccaac
accagccccatgggcttcctccggccgggatcatgctccccagtaccagcagacacagca
cagacagttggacgaaggctctccactgggtcttctaggccttactcaccttcccctttg
gttggtaccattcctgagcaattcagtcagtgctgctgtgggcatcctcagggccatgac
tccaggagtagaaactcctcaggttctccagtgccacaagctcagtccccacagtctctc
ttatcgggtgctagactgcagagcgcccccaccctcactgacatctatcagaacaagcag
aagctcagaaaacagcactctgaccccgtgtgcccatcccatactggggctgggtacagc
tactcgcctcagcccagtcggcctggcagccttggaacttctcccaccaagcacttgggg
tcctctccacggagttctgactggttctttaaaactcctttgccaacaatcattggctct
cctactaagaccacagctcctttcaaaatccctaaaactcaagcatcttccaacctgtta
gccttggttactcgtcatgggcctgctgaagaacagtcgaaagatgggaatgagccacgg
gaatgtgcccattgcctcttagtgcaaggaagtgagaggcagcgggccgagcagcagagc
aaggcagtgtttggcagatctgtcagtaccgggaagttatcagatcaacaaggaaagact
cctatatgtcgacatcagggcagcacagacagtttaaatacagaacgaccaatggatata
gctccggcaggagcctgtggtggtgttctggcacctcctgcaggtacagcagcaagttcc
aaggctgtcctcttcactgtagggtctcctccacacagtgcggcagcccccacttgtacc
cacatgttccttcgaacaagaacaacctcagtggggcccagcaactccgggggctctctt
tgtgccatgagtggccgcgtgtgcgtggggtccccgcctggcccaggcttcggctcttcc
cctccaggagcagaggcagctcccagcctgagatacgtgccttacggtgcttcacccccc
agcctagaggggctcatcacctttgaagcccctgaactgccggaggagacgctgatggag
cgggaacacacagacaccttacgccatctgaatgtgatgctgatgttcactgagtgtgtg
ctggacctgacagccatgaggggaggaaaccctgagctgtgcacatctgctgtgtccttg
taccagatccaggagagtgtggtggtggaccagatcagtcagctgagcaaagactggggg
cgggtggagcagctggtgttgtacatgaaagcagcacagctgcttgcggcttctctgcat
cttgccaaagcccagatcaagtccgggaaactgagcccatccacagctgtgaaacaagtt
gtcaagaatctgaacgaacgatataaattctgcatcaccatgtgcaagaaacttacagaa
aagctgaatcgattcttctctgacaaacagaggtttattgatgaaatcaacagtgtgact
gcagagaaactcatctataattgtgctgtagaaatggttcagtctgcagccctggatgag
atgtttcagcagaccgaagatattgtttatcgctatcataaggcagcccttcttttggaa
ggcctaagtaggattctacaggaccctgcagatattgaaaatgtgcataaatataaatgt
agtattgagagaagactgtcggcgctctgccatagcaccgcaaccgtgtga

All links

Pathway (2)   
   KEGG PATHWAY (2)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (12)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (4)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (16)   
   RefSeq(nuc) (2)   
   GenBank (7)   
   EMBL (7)   
Protein domain (8)   
   Pfam (8)   
All databases (44)   

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