KEGG   Homo sapiens (human): 9820Help
Entry
9820              CDS       T01001                                 

Gene name
CUL7, 3M1, KIAA0076, dJ20C7.5
Definition
(RefSeq) cullin 7
  KO
K10613  
cullin 7
Organism
hsa  Homo sapiens (human)
Pathway
Ubiquitin mediated proteolysis
Disease
H00509  
3M syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Genetic Information Processing
  Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    9820 (CUL7)
Ubiquitin system [BR:hsa04121]
 Ubiquitin ligases (E3)
  Multi subunit Ring-finger type E3
   Cul7 complex
    Cullin
     9820 (CUL7)
Chromosome [BR:hsa03036]
 Eukaryotic Type
  Centrosome formation and ciliogenesis proteins
   3M complex
    9820 (CUL7)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-ProteinID: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Structure
PDB: 

Jmol
Position
6p21.1
AA seq 1698 aa AA seqDB search
MVGELRYREFRVPLGPGLHAYPDELIRQRVGHDGHPEYQIRWLILRRGDEGDGGSGQVDC
KAEHILLWMSKDEIYANCHKMLGEDGQVIGPSQESAGEVGALDKSVLEEMETDVKSLIQR
ALRQLEECVGTIPPAPLLHTVHVLSAYASIEPLTGVFKDPRVLDLLMHMLSSPDYQIRWS
AGRMIQALSSHDAGTRTQILLSLSQQEAIEKHLDFDSRCALLALFAQATLSEHPMSFEGI
QLPQVPGRVLFSLVKRYLHVTSLLDQLNDSAAEPGAQNTSAPEELSGERGQLELEFSMAM
GTLISELVQAMRWDQASDRPRSSARSPGSIFQPQLADVSPGLPAAQAQPSFRRSRRFRPR
SEFASGNTYALYVRDTLQPGMRVRMLDDYEEISAGDEGEFRQSNNGVPPVQVFWESTGRT
YWVHWHMLEILGFEEDIEDMVEADEYQGAVASRVLGRALPAWRWRPMTELYAVPYVLPED
EDTEECEHLTLAEWWELLFFIKKLDGPDHQEVLQILQENLDGEILDDEILAELAVPIELA
QDLLLTLPQRLNDSALRDLINCHVYKKYGPEALAGNQAYPSLLEAQEDVLLLDAQAQAKD
SEDAAKVEAKEPPSQSPNTPLQRLVEGYGPAGKILLDLEQALSSEGTQENKVKPLLLQLQ
RQPQPFLALMQSLDTPETNRTLHLTVLRILKQLVDFPEALLLPWHEAVDACMACLRSPNT
DREVLQELIFFLHRLTSVSRDYAVVLNQLGARDAISKALEKHLGKLELAQELRDMVFKCE
KHAHLYRKLITNILGGCIQMVLGQIEDHRRTHQPINIPFFDVFLRYLCQGSSVEVKEDKC
WEKVEVSSNPHRASKLTDHNPKTYWESNGSAGSHYITLHMRRGILIRQLTLLVASEDSSY
MPARVVVCGGDSTSSLHTELNSVNVMPSASRVILLENLTRFWPIIQIRIKRCQQGGIDTR
IRGLEILGPKPTFWPVFREQLCRHTRLFYMVRAQAWSQDMAEDRRSLLHLSSRLNGALRQ
EQNFADRFLPDDEAAQALGKTCWEALVSPVVQNITSPDEDGISPLGWLLDQYLECQEAVF
NPQSRGPAFFSRVRRLTHLLVHVEPCEAPPPVVATPRPKGRNRSHDWSSLATRGLPSSIM
RNLTRCWRAVVEKQVNNFLTSSWRDDDFVPRYCEHFNILQNSSSELFGPRAAFLLALQNG
CAGALLKLPFLKAAHVSEQFARHIDQQIQGSRIGGAQEMERLAQLQQCLQAVLIFSGLEI
ATTFEHYYQHYMADRLLGVVSSWLEGAVLEQIGPCFPNRLPQQMLQSLSTSKELQRQFHV
YQLQQLDQELLKLEDTEKKIQVGLGASGKEHKSEKEEEAGAAAVVDVAEGEEEEEENEDL
YYEGAMPEVSVLVLSRHSWPVASICHTLNPRTCLPSYLRGTLNRYSNFYNKSQSHPALER
GSQRRLQWTWLGWAELQFGNQTLHVSTVQMWLLLYLNDLKAVSVESLLAFSGLSADMLNQ
AIGPLTSSRGPLDLHEQKDIPGGVLKIRDGSKEPRSRWDIVRLIPPQTYLQAEGEDGQNL
EKRRNLLNCLIVRILKAHGDEGLHIDQLVCLVLEAWQKGPCPPRGLVSSLGKGSACSSTD
VLSCILHLLGKGTLRRHDDRPQVLSYAVPVTVMEPHTESLNPGSSGPNPPLTFHTLQIRS
RGVPYASCTATQSFSTFR
NT seq 5097 nt NT seq  +upstreamnt  +downstreamnt
atggtgggagaactccgctacagggaattcagggtgcccctggggcccggcttacatgcc
tatcctgatgagctgatccgccagcgcgtgggccatgatgggcatcctgagtaccagatc
cgttggctcatcctgcggcgtggcgatgagggggacgggggctctggccaagtggactgc
aaggctgagcacatcctgctgtggatgtccaaggatgagatctatgccaactgccacaag
atgctgggcgaggatggccaggtcatcgggccctcccaggagtctgcaggggaggttggg
gccctggacaaatctgtgctggaggagatggaaaccgacgtgaagtccctcattcagaga
gcccttcggcagctggaggagtgtgtgggcactatccctcctgctcctctacttcacact
gtccacgtgctcagcgcctatgccagcattgagcccctcactggagtattcaaggaccca
agggtcctggacttgctcatgcacatgttgagtagtcctgattatcagattcgctggagt
gcaggccggatgatacaagccctgtcctcccatgacgctgggacccggactcagatcctt
ctgtcactgagccaacaagaagccattgagaaacacctggattttgacagccgctgtgct
ctgctagcactgtttgcacaggccacgctctctgaacaccccatgtctttcgagggcatt
cagctaccacaggtcccaggaagggtgctcttctccctggtgaagcggtatttgcatgtc
acctcgctcctggatcagctgaacgacagtgctgcggagccaggagcccagaacacctct
gctcctgaggagttgagtggggagaggggtcaactggagctggagttcagtatggccatg
ggcaccctgatctcggagctggtgcaagccatgcgctgggaccaggcctcagacagacca
aggagctcagcacggtcccccggttccatcttccagcctcagctggcagatgtgagccca
gggctccccgctgcccaggctcagccctccttcaggaggtcaagacgttttcgccctcgt
tctgagttcgcaagtggcaatacctatgctttgtatgtgcgggacacactgcagccgggg
atgcgagtgcggatgctggatgattatgaggagatcagtgccggggatgagggcgagttt
cggcagagcaacaacggtgtgcctcctgtgcaggtattttgggagtcaacaggccgcacc
tattgggtgcactggcacatgctggagatcttgggctttgaggaagacattgaggacatg
gttgaggctgatgagtaccaaggggcagtggccagtagagtcctgggtagagccctgcct
gcctggcgctggaggcccatgacagaactctatgctgtgccttatgtgctgcctgaggat
gaggacactgaggagtgtgaacacctgaccctggctgagtggtgggaactcctcttcttc
atcaagaagctggatggacctgaccatcaggaggttctccagatcctccaggagaaccta
gatggggagattctggatgatgagatcctagctgaactggccgtgcccatagaattggcc
caggacttgctgctgactctgccacagcgactcaatgacagtgccctcagggacctgatc
aactgccatgtctacaagaagtatgggcctgaagccctagcagggaaccaagcctaccca
tcccttctagaagcccaagaagatgtcctcctgctagacgcgcaggcccaggctaaggac
tcagaagatgcagccaaagtggaagcaaaagaacccccatctcagagtcccaacactccc
ctgcagcgtctggtggagggttatggtccagctgggaaaatcctcctggatctagagcaa
gccctcagctcagaggggacccaggagaacaaggtcaagccactcctgctgcagctgcag
cggcagccgcagcccttcctggcactgatgcagagcctggacactccggagactaacagg
accctgcacctgactgtgctgagaatcctgaagcagctggtggacttccccgaggcactg
ctgctcccctggcacgaggccgtggatgcctgcatggcctgcctgcggtccccaaacact
gatcgagaggtgctccaggaactgattttcttcctgcaccgcctgacctcagtgagcagg
gactatgccgtggtgctgaatcagctgggagcaagagacgctatctccaaggccctggaa
aagcacctgggaaagctggagctggctcaggagctgcgggacatggtgttcaagtgtgag
aagcatgcccacctctaccgcaaactcatcaccaacatcctgggaggctgcatccagatg
gtgctgggccagatcgaagaccacagacgaacccaccaacccatcaacatccctttcttt
gatgtgttcctcagatacctgtgccagggctccagtgtggaagtgaaggaggacaagtgc
tgggagaaggtggaggtgtcctccaacccgcaccgggccagcaagctgacggaccacaac
cccaagacctattgggagtccaacggcagcgccggctcccactacatcaccctgcacatg
cgccggggcatcctcatcaggcaactgactctgcttgtggctagtgaggactcgagttac
atgccggcccgagtggtggtgtgcgggggtgatagcactagctctcttcacacggaactc
aactcggtgaatgtgatgccctctgccagccgggtgatcctcctggagaacctgacccgc
ttctggcccatcatccagatccgcataaagcgctgccagcagggtggcattgatacgcgc
attcgggggttagagatcctaggccccaagcccacgttctggccagtgttccgggagcag
ctctgtcgtcacacacgcctcttctacatggttcgggcacaggcctggagccaggacatg
gcagaggaccgcaggagcctcctgcacctgagttctagactcaacggtgctctgcgccag
gagcagaattttgctgaccgcttcctccctgatgacgaggctgcccaagctctgggcaag
acctgctgggaggccctggtcagccccgtggtgcagaacatcacctcccctgatgaggat
ggcattagccccctgggttggctgctggaccagtacctggagtgtcaggaagctgtcttc
aacccccagagccgcggcccagctttcttctcgcgggtgcgccgtctcactcacctgctg
gtgcatgtcgagccctgtgaggcaccccctcctgtggtggccactcctcggcccaaaggc
agaaacagaagccacgactggagctccttggctacccggggccttccaagcagcatcatg
agaaacctgacgcgctgttggcgggccgtggtggagaagcaggtgaacaattttctgacc
tcatcctggcgggatgatgactttgtgccacgctactgtgagcactttaatattctgcag
aactcaagctctgaactgtttgggcctcgggcagccttcttgctggcgctgcaaaatggc
tgtgcgggagccttgctgaagctcccttttctcaaagctgcccacgtgagtgagcagttc
gcccggcacattgaccagcagatccagggcagccggatcggtggagcccaggaaatggag
aggctggcacagctgcagcaatgcctgcaagctgtcctgattttctccggcttggagata
gccaccacttttgagcattattaccagcactacatggcggaccgtctcctgggcgtggtc
tcgagctggctggagggggccgtgctggagcagatcggtccctgcttccccaaccgcctc
ccccagcagatgttgcagagcctgagcacctctaaggagctgcagcgccagttccacgtc
taccagctccagcagctggatcaggaactcctgaagctggaggatacagagaagaaaata
caggtgggccttggggccagtggcaaggagcacaagagcgagaaggaagaggaagctggg
gcagcagcagtggtggatgtggcggagggagaggaggaagaggaggagaatgaggacctc
tactatgaaggggcaatgccagaagtgtctgtgcttgtcctgtcccgacactcctggcct
gttgcctcaatctgccacacactgaaccccagaacctgcctgccctcctacctgaggggc
actttgaacagatactccaacttctacaacaagagtcagagccaccctgcccttgagcga
ggctcacagaggcgactgcagtggacgtggctgggctgggctgagctgcagtttgggaac
cagaccctgcatgtgtccaccgtgcagatgtggctactgctgtatctcaacgacctgaag
gcggtctctgtggagagtctgctggcgttctcagggctctccgcagacatgctcaatcag
gcgattgggcccctcacctcttcaagaggccccctggaccttcacgagcaaaaggatata
ccaggaggggtcctcaagattcgagatggcagcaaggaacccaggtcgagatgggacatt
gtgcggctcatcccacctcagacgtacctgcaagctgagggtgaagacggccagaacttg
gagaagagacggaatcttctgaactgcctcatcgtccgaatcctcaaggcccatggagat
gaggggctgcacattgaccagcttgtctgtctggtgctggaggcttggcagaagggcccg
tgtcctcccaggggtttggtcagcagccttggtaaggggtctgcatgcagcagcactgac
gtcctctcctgcatcctacacctcctgggcaagggcacgctgagacgccatgacgaccgg
ccccaggtgctgtcctatgcagtccctgtgactgtcatggagcctcacactgagtccctg
aacccaggctcctcaggccccaacccacccctcaccttccataccctacagattcgctcc
cggggtgtgccctatgcctcctgcactgccacccagagcttctctaccttccggtag

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