KEGG T01001: 9887

Homo sapiens (human): 9887

Entry

9887 CDS T01001

Gene name

SMG7, C1orf16, EST1C, SGA56M

Definition

smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans) (EC:2.7.11.1)

Orthology

K14409

protein SMG7

Organism

hsa Homo sapiens (human)

Pathway

hsa03015

mRNA surveillance pathway

Class

Genetic Information Processing; Translation; mRNA surveillance pathway [PATH:hsa03015]

SSDB

Motif

Pfam:

EST1_DNA_bind EST1 TPR_11 zf-AD TPR_12 TPR_2 TPR_17 TPR_8 TPR_7

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

Q92540 B4DRB2 E9PCI0 E9PEH2 Q6TV06

Structure

PDB:

1YA0

Position

1q25

AA seq 1145 aa
MLVTDLEYALDKKVEQDLWNHAFKNQITTLQGQAKNRANPNRSEVQANLSLFLEAASGFY
TQLLQELCTVFNVDLPCRVKSSQLGIISNKQTHTSAIVKPQSSSCSYICQHCLVHLGDIA
RYRNQTSQAESYYRHAAQLVPSNGQPYNQLAILASSKGDHLTTIFYYCRSIAVKFPFPAA
STNLQKALSKALESRDEVKTKWGVSDFIKAFIKFHGHVYLSKSLEKLSPLREKLEEQFKR
LLFQKAFNSQQLVHVTVINLFQLHHLRDFSNETEQHTYSQDEQLCWTQLLALFMSFLGIL
CKCPLQNESQEESYNAYPLPAVKVSMDWLRLRPRVFQEAVVDERQYIWPWLISLLNSFHP
HEEDLSSISATPLPEEFELQGFLALRPSFRNLDFSKGHQGITGDKEGQQRRIRQQRLISI
GKWIADNQPRLIQCENEVGKLLFITEIPELILEDPSEAKENLILQETSVIESLAADGSPG
LKSVLSTSRNLSNNCDTGEKPVVTFKENIKTREVNRDQGRSFPPKEVRRDYSKGITVTKN
DGKKDNNKRKTETKKCTLEKLQETGKQNVAVQVKSQTELRKTPVSEARKTPVTQTPTQAS
NSQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHS
PAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQ
ALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYL
QTQDPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRS
VMAQQANIDRRGKRSPGVFRPEQDPVPRMPFEDPKSSPLLPPDLLKSLAALEEEEELIFS
NPPDLYPALLGPLASLPGRSLFKSLLEKPSELMSHSSSFLSLTGFSLNQERYPNNSMFNE
VYGKNLTSSSKAELSPSMAPQETSLYSLFEGTPWSPSLPASSDHSTPASQSPHSSNPSSL
PSSPPTHNHNSVPFSNFGPIGTPDNRDRRTADRWKTDKPAMGGFGIDYLSATSSSESSWH
QASTPSGTWTGHGPSMEDSSAVLMESLKSIWSSSMMHPGPSALEQLLMQQKQKQQRGQGT
MNPPH

NT seq 3438 nt +upstreamnt +downstreamnt
atgctagttaccgatttggaatacgctttagacaagaaagtagaacaggatctctggaat
cacgcctttaagaatcagatcacaacactgcaaggccaggcaaagaatcgagcaaatccg
aatcggagtgaagttcaggcaaacctttctctgttcctagaggcagctagtggcttctat
actcagttattacaagaactgtgtacagtatttaatgtagatttaccatgccgtgtgaag
tcttcccaattgggaattatcagcaataaacagacgcataccagcgccatagtgaagcca
cagtctagctcctgttcctatatctgccagcactgcctcgtccaccttggagacattgct
cgatacagaaaccagaccagccaggcagagtcctactataggcatgcagctcagcttgtc
ccctccaatggtcagccttataatcagttggctatcttagcttcttccaaaggagaccat
ctgaccacaattttctactactgcagaagcattgctgtgaagttccctttcccagctgcc
tccactaatctgcaaaaagcactttctaaagcactggaaagccgagatgaggtgaaaacc
aagtggggtgtttctgacttcatcaaggcctttattaaattccacggtcatgtgtacctg
agtaagagcttggaaaagttgagccctcttcgagagaaattggaagaacagtttaagagg
ctgctattccaaaaagctttcaactctcagcagttagttcatgtcactgtcattaacctg
tttcaacttcatcaccttcgtgactttagcaatgaaaccgagcagcacacttatagccaa
gatgagcagctatgttggacacagttgctggccctctttatgtcttttcttggcatcctg
tgcaagtgtcctctacagaatgagtctcaggaggagtcctacaatgcctatcctcttcca
gcagtcaaggtctccatggactggctaagactcagacccagggtctttcaggaggcagtg
gtggatgaaagacagtacatttggccctggttgatttctcttctgaatagtttccatccc
catgaagaggacctctcaagtattagtgcgacaccacttccagaggagtttgaattacaa
ggatttttggcattgagaccttctttcaggaacttggatttttccaaaggtcaccagggt
attacaggggacaaagaaggccagcaacgacgaatacgacagcaacgcttgatctctata
ggcaaatggattgctgataatcagccaaggctgattcagtgtgaaaatgaggtagggaaa
ttgttgtttatcacagaaatcccagaattaatactggaagaccccagtgaagccaaagag
aacctcattctgcaagaaacatctgtgatagagtcgctggctgcagatgggagcccaggg
ctaaaatcagtgctatctacaagccgaaatttaagcaacaactgtgacacaggagagaag
ccagtggttaccttcaaagaaaacattaagacacgagaagtgaacagagaccaaggaaga
agttttcctcccaaagaggtgagaagggactatagcaaaggaataactgtaactaagaat
gatggaaagaaggacaacaacaagaggaaaactgaaaccaagaaatgcaccttagaaaag
ttacaggaaacaggaaagcagaatgtggcagtgcaggtaaaatcccagacagaactaaga
aagactccagtgtctgaagccagaaaaacacctgtaactcaaaccccaactcaagcaagt
aactcccagttcatccccattcatcaccctggagccttccctcctcttcccagcaggcca
gggtttccgcccccaacatatgttatccccccgcctgtggcattttctatgggctcaggt
tacaccttcccagctggtgtttctgtcccaggaacctttcttcagcctacagctcactct
ccagcaggaaaccaggtgcaagctgggaaacagtcccacattccttacagccagcaacgg
ccctctggaccagggccaatgaaccagggacctcaacaatcacagccaccttcccagcaa
ccccttacatctttaccagctcagccaacagcacagtctacaagccagctgcaggttcaa
gctctaactcagcaacaacaatcccctacaaaagctgtgccggctttggggaaaagcccg
cctcaccactctggattccagcagtatcaacaggcagatgcctccaaacagctgtggaat
ccccctcaggttcaaggcccattagggaaaattatgcctgtgaaacagccctactacctt
cagacccaagaccccataaaactgtttgagccgtcattgcaacctcctgtaatgcagcag
cagcctctagaaaaaaaaatgaagccttttcccatggagccatataaccataatccctca
gaagtcaaggtcccagaattctactgggattcttcctacagcatggctgataacagatct
gtaatggcacagcaagcaaacatagaccgcaggggcaaacggtcaccaggagtcttccgt
ccagagcaggatcctgtacccagaatgccgtttgaggaccccaagagctcccctctgctt
cctccggacctgttaaagagtctggctgccttggaggaagaggaagagctgattttttct
aaccctcctgatctttacccggctctgctggggcctctcgcctctcttcctggacgaagc
ctttttaaatccttattggagaagccctcagagctcatgtcacattcatcctctttcctg
tccctcaccggattctctctcaatcaggaaagatacccaaataatagtatgttcaatgag
gtatatgggaaaaacctgacatccagctccaaagcagaactcagtccctcaatggccccc
caggaaacatctctgtattccctttttgaagggactccgtggtctccatcacttcctgcc
agttcagatcattcaacaccagccagccagtctcctcattcctctaacccaagcagccta
cccagctctcctccaacacacaaccataattctgttccattctccaattttggacccatt
gggactccagataacagggatagaaggactgcagatcggtggaaaactgataagccagcc
atgggtgggtttggcattgattatctctcagcaacgtcatcctctgagagcagttggcat
caggccagcactccgagtggcacctggacaggccatggcccttccatggaggattcctct
gctgtcctcatggaaagcctaaagtctatctggtccagttccatgatgcatcctggacct
tctgctctggagcagctgttaatgcagcagaagcagaaacagcaacggggacaaggcacc
atgaaccctccacactga

All links

Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (18)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (10)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (9)   
   UniProt (5)   
   RefSeq(pep) (4)   
DNA sequence (41)   
   RefSeq(nuc) (5)   
   GenBank (18)   
   EMBL (18)   
3D Structure (1)   
   PDB (1)   
Protein domain (9)   
   Pfam (9)   
All databases (81)   

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