KEGG   Juglans regia (English walnut): 108991352
Entry
108991352         CDS       T05245                                 
Name
(RefSeq) putative bifunctional dihydrofolate reductase-thymidylate synthase isoform X2
  KO
K13998  dihydrofolate reductase / thymidylate synthase [EC:1.5.1.3 2.1.1.45]
Organism
jre  Juglans regia (English walnut)
Pathway
jre00240  Pyrimidine metabolism
jre00670  One carbon pool by folate
jre00790  Folate biosynthesis
jre01100  Metabolic pathways
jre01232  Nucleotide metabolism
jre01240  Biosynthesis of cofactors
Module
jre_M00126  Tetrahydrofolate biosynthesis, GTP => THF
jre_M00938  Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP
Brite
KEGG Orthology (KO) [BR:jre00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00240 Pyrimidine metabolism
    108991352
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    108991352
   00670 One carbon pool by folate
    108991352
Enzymes [BR:jre01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     108991352
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.45  thymidylate synthase
     108991352
SSDB
Motif
Pfam: Thymidylat_synt DHFR_1
Other DBs
NCBI-GeneID: 108991352
NCBI-ProteinID: XP_018821107
UniProt: A0A2I4ENX8
Position
11:29508658..29514768
AA seq 573 aa
MFKFFQFKQQIIVERVFSLHILVYCFLNLASVAPSRLFGVLNVPQKYRSYPRFSVMAGGT
PMSSSNCDVDADPGRTYQVVLAATREMGIGKDGKLPWRLPSDLKFFKELTTATSDPGKKN
AVVMGRKTWESIPLEYRPLPGRLNVVLTRSGSTDIATAENVVICGSIPSALKLLAESTYS
LSVEKVFIIGGSQILREALNSSQCAAIHITEIETSIECDTFTPNIDFSVFQPWYSSSPLV
ENHIRYSFVSYVRVRSSAIEARASRSEDSSKFDVERFTFLPKMIFEKHDEYVYLKLVQEI
ISSGTQKDDRTGTGTLSKFGCQMRFNLRRSFPLLTTKRVFWRGVVEELLWFISGSTNAKV
LQEKDVHIWDGNGSRDFLDSIGLPDREEGDLGPIYGFQWRHFGARYTNMHADYTSQGFDQ
LSDIIDKIKNRPDDRRIILSAWNPQDLKLMALPPCHMFAQFYVANGELSCQMYQRSADMG
LGVPFNIASYALLTCMIAHVCGLFPGDFIHIIGDAHVYKTHIRPLQEQLQKLPKPFPILK
INPAKKDIDSFVAADFELVGYDPHQEIEMKMAV
NT seq 1722 nt   +upstreamnt  +downstreamnt
atgtttaagttctttcaatttaagcagcaaataatagtcgaacgtgtcttttcccttcac
atactcgtatattgctttcttaatctcgcttctgttgcaccctcacgcttatttggagta
ttgaatgtgcctcagaagtacagatcttacccaagattttctgtcatggctggtggcact
ccaatgagtagctctaactgtgatgtggatgctgatcccggaaggacttaccaagttgtg
ctggctgctactcgtgaaatgggtattgggaaggatggaaaattgccatggaggttgcct
tctgacctcaaatttttcaaggagctcacgacagccacatcagatcctgggaagaagaat
gcagtggtaatgggtaggaaaacatgggaaagtatccccctcgagtaccgtcctttacct
ggtcgcctgaatgttgtactgactcgttctggaagtactgatattgcaactgctgaaaat
gttgtaatatgtggaagcattccttcagctttaaaattattggccgaatctacttattct
ttgtcggtagagaaagtgtttattattggaggcagccagatactaagggaagcactcaat
tcttcacaatgtgctgccatccacattactgaaattgagacaagcattgaatgcgacact
ttcactcccaatattgatttctccgtatttcagccatggtactcatcctccccattggtg
gaaaatcatatacgatattcttttgtgagttatgttcgtgtaagaagttccgcaattgaa
gctcgtgcttcaaggagtgaggattccagtaagtttgacgtagaaaggtttaccttcctg
ccaaagatgatatttgagaaacatgatgagtacgtgtatctgaaattggttcaagaaatt
atctctagtggcacccagaaagacgacaggacagggactggtactttatctaaatttggt
tgccagatgcggttcaatcttcgcagatctttcccgcttcttacaactaagagagtattt
tggcgaggagttgttgaagaactgttgtggtttatcagtggctcaacaaatgcgaaggtt
ctacaggagaaagacgtacatatatgggatggaaatggatccagagacttccttgacagt
attggtttgccagatagggaagaaggtgacttgggacccatttatggattccagtggaga
cacttcggtgctagatataccaatatgcatgctgactatacaagccaagggtttgatcag
ttgtcagatattattgacaagatcaagaatagacctgatgacaggcgaattatcctctca
gcctggaatccacaagatcttaagttgatggcacttcccccttgtcatatgttcgctcag
ttctatgtagccaatggggagctttcatgtcaaatgtatcagcggtctgctgatatgggt
cttggtgttccatttaacattgcgtcttatgctttattgacatgtatgatcgctcatgtt
tgtggcctatttcctggtgattttattcatataattggggatgcccatgtttataaaact
catatcaggcctctacaggagcagcttcagaaacttcccaaaccttttcctattttgaag
atcaatccagcaaagaaagacatagattcatttgtggcagctgactttgaacttgtaggc
tatgatcctcaccaggagatagaaatgaaaatggcagtgtag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (9)   
   KEGG PATHWAY (6)   
   KEGG MODULE (3)   
Chemical substance (11)   
   KEGG COMPOUND (11)   
Chemical reaction (9)   
   KEGG ENZYME (2)   
   KEGG REACTION (7)   
Genome (1)   
   KEGG GENOME (1)   
Gene (31)   
   KEGG ORTHOLOGY (1)   
   RefGene (27)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (6)   
   UniProt (1)   
   RefSeq(pep) (5)   
DNA sequence (6)   
   RefSeq(nuc) (6)   
Protein domain (2)   
   Pfam (2)   
All databases (77)   

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