KEGG   Kluyveromyces marxianus: KLMA_60087
Entry
KLMA_60087        CDS       T05269                                 
Symbol
ADE3
Name
(RefSeq) C-1-tetrahydrofolate synthase
  KO
K00288  methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase / formyltetrahydrofolate synthetase [EC:1.5.1.5 3.5.4.9 6.3.4.3]
Organism
kmx  Kluyveromyces marxianus
Pathway
kmx00670  One carbon pool by folate
kmx01100  Metabolic pathways
kmx01240  Biosynthesis of cofactors
Module
kmx_M00141  C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:kmx00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    KLMA_60087 (ADE3)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:kmx04147]
    KLMA_60087 (ADE3)
Enzymes [BR:kmx01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.5  methylenetetrahydrofolate dehydrogenase (NADP+)
     KLMA_60087 (ADE3)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.9  methenyltetrahydrofolate cyclohydrolase
     KLMA_60087 (ADE3)
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.4  Other carbon-nitrogen ligases
    6.3.4.3  formate---tetrahydrofolate ligase
     KLMA_60087 (ADE3)
Exosome [BR:kmx04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   KLMA_60087 (ADE3)
SSDB
Motif
Pfam: FTHFS THF_DHG_CYH_C THF_DHG_CYH CbiA AlaDh_PNT_C Shikimate_DH
Other DBs
NCBI-GeneID: 34717314
NCBI-ProteinID: XP_022677171
Position
6:complement(193745..196591)
AA seq 948 aa
MTIIDGKAIANGIRQEIKEGISGLKQKYAAFRPTLTIFQIGNRQDSNTYVRMKLKAAKEA
GIEVRFIHLEESVSELEVLAKIDDENDDESVHGILVQLPLPKHLNEDKITSRVAASKDVD
GFGPFNIGELNKRNGKPFFEPCTPKGIIELLKRSGVTIAGAEAVVIGRSDIVGSPVATLL
TSLDATVTILHSKSKDLHKFLENADIVIVAIGQPEFIKGEWFANNKRGAVVIDVGTNFVE
DASKKSGYRNVGDVEFAAAEPYVKLITPVPGGVGPMTVAMLMQNTFESAQRALDRQLNVG
GNDFEPLPLNLVKPVPSDFEISRAQIHKPITQIAKESGILPSELEPYGDTKAKVKLDILN
RLKDRENGKYVLVTGITPTPLGEGKSTTTVGLAQALGAHLKKKVFANVRQPSMGPTFGIK
GGAAGGGYSQVIPMDEFNLHVTGDIHAISMANNLLAAAIDTRMFHESTQSNAALYKRLVP
TKKGVRKFTPTMLRRLKKLGIDKTDPNELTEEESARFARLDIDPDTITWRRVVDCNDRFL
RGITVGQAPTERGHTRSTGFDISVASECMAVLALANSLEDMRERLGRIVIAASKSGEPIT
CEDIGCAGAMTALLKDAIKPNIMQTLEGTPVFVHAGPFANISIGANSVLADKMALKLAGV
PQELPQDVKDSQKGYVITEAGFDFTMGGERFINIKCRSSGLVPDVVVIVATVRALKVHGG
GPEVKAGAPLPAEYLHEDVELLRKGCANLAKHISNARAYNLPVVVAINRMSSDTDKEHEV
IREESIKAGAVDAIVSNHWEEGGKGAVNLAEGIIKAANEESNKDFKFLYDVEGSSVEDKI
SAIAKEMYGAGEVEFLPEAQAKIDLYTKQGFSNLPICIAKTQYSLSHDANLKGVPTGFKF
PIRDVRASIGAGYLYALAAEIQTIPGLPTHCGFMNIEVNEDGEIDGMF
NT seq 2847 nt   +upstreamnt  +downstreamnt
atgactattatcgacggtaaagcgattgccaatgggatcagacaggagatcaaggagggc
atttctggcttgaaacagaaatatgcggcattccgccccacattgaccattttccagatc
ggaaacagacaggattccaatacgtatgtgagaatgaagctaaaggcagccaaagaagct
ggcattgaagtgaggttcatccatctcgaggaatcagtgtctgagctagaggtgcttgcc
aagattgatgatgaaaatgacgatgagtcggtgcacggtattctagtgcaattgcctctt
ccaaagcatctaaacgaggataagatcacgtcacgtgtggcagcatccaaggacgtggat
gggttcggtccattcaacattggggagttgaacaagcgtaacggtaagccattcttcgag
ccatgcacgcccaagggtattatcgagcttttgaaaagatctggcgtcacaattgccggt
gcagaagcggttgtcattggaagatccgatatcgttgggtctccagttgcaacgttgttg
acctctcttgatgccacggtgaccattttgcactccaagtcgaaggatttgcacaagttc
ttggaaaatgccgatattgttatcgttgccattggccagccggagttcatcaagggcgag
tggtttgccaacaacaagcgtggtgccgttgtcatcgatgtgggcacgaacttcgtcgag
gatgcaagcaagaaatcgggctacagaaacgtcggggacgtggagtttgcagctgctgag
ccatacgtgaagttgatcacgcctgtgccaggcggtgtcggacccatgaccgttgccatg
ttgatgcagaacactttcgagagcgcacaaagagcgttagatcgccaattgaacgtcgga
gggaacgacttcgagccattgcctctaaacttggtgaaaccagtgccatcggactttgag
atctcgagagctcaaatccacaagccaatcacccaaatcgccaaggaatccggtattcta
ccctccgaattggagccatacggtgataccaaggccaaggttaagttggatatcttgaac
agattgaaggaccgtgaaaacggtaagtacgttctagtcacaggtatcactccaactcca
ttgggtgaaggtaagtccacaactacagttggtttagcgcaagcgctaggtgcccacctg
aagaagaaggttttcgccaacgtgcgtcaaccttccatgggacccaccttcggtatcaag
ggtggtgctgccggtggtggttactctcaagttattccaatggacgagttcaacttgcac
gtcactggtgatatccatgccatttccatggctaacaacttgttggctgcagctattgac
acaagaatgttccacgagtctacccaatccaacgcagccctttacaagagacttgtccca
actaaaaagggcgttagaaagttcactccaaccatgttgagaaggttgaagaagttgggc
atcgacaagacagatccaaacgagctaacagaagaagagagcgcaagattcgctagatta
gacattgacccagacaccatcacttggagacgtgttgttgactgtaacgatagattcttg
agaggaatcaccgtgggtcaagctccaaccgaacgtggtcataccagatctactggtttc
gatatctctgttgcctctgagtgtatggccgttcttgctttggctaactcgttggaagac
atgagagaaagattaggtagaatcgttattgctgcttcgaaatcgggcgaaccaattact
tgtgaagacatcggatgcgctggcgcaatgactgcgttgttgaaggacgctatcaagcca
aatatcatgcaaactttggaaggtactcctgtgtttgttcacgctggtccattcgccaac
atttcgatcggtgccaactctgtattggctgataagatggccttgaagttggccggtgtt
ccacaggaactacctcaggatgtcaaggattcccaaaagggttacgtgattacagaagcc
ggtttcgatttcactatgggtggtgaaagattcatcaatatcaagtgtagatccagtggt
ttggttccagatgttgtcgttatcgttgccactgttagagctctaaaagttcacggtggt
ggtccagaggttaaagctggtgctccattgcctgctgaatatctacacgaagatgttgaa
ttgttaagaaaaggttgtgccaacttggcaaagcacatttcaaacgccagagcttacaat
ctacctgttgttgttgcaattaacagaatgtcttctgacactgacaaggaacacgaagtt
attagagaagaatctatcaaggctggtgctgtggacgccatagtgtcaaaccactgggaa
gaaggtggtaagggtgctgtgaacttggctgaaggtatcatcaaggccgctaatgaagaa
tcaaacaaggacttcaagttcttgtacgacgtggaaggtagcagcgttgaagataaaatc
tctgccattgccaaggagatgtatggtgctggtgaagtggagttcttgccagaggcacaa
gctaagatcgatctttacacaaaacaaggtttcagcaacttaccaatctgtattgctaag
acccaatactctttgtcacacgatgcaaacttaaagggtgtgccaactgggttcaagttc
ccaattagagatgtgagagcatctattggtgcaggatacttgtacgcgctagcagctgaa
attcaaaccattcctggtctaccaacacactgtggtttcatgaacatcgaagttaacgaa
gacggtgaaatcgacggtatgttctga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (4)   
   KEGG PATHWAY (3)   
   KEGG MODULE (1)   
Chemical substance (12)   
   KEGG COMPOUND (12)   
Chemical reaction (6)   
   KEGG ENZYME (3)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (6)   
   Pfam (6)   
All databases (38)   

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