KEGG   ORTHOLOGY: K00139Help
Entry
K00139                      KO                                     

Name
ALDH5A1
Definition
succinate-semialdehyde dehydrogenase [EC:1.2.1.24]
Pathway
ko00250  Alanine, aspartate and glutamate metabolism
ko00650  Butanoate metabolism
ko01100  Metabolic pathways
ko01120  Microbial metabolism in diverse environments
Module
M00027  GABA (gamma-Aminobutyrate) shunt
Disease
H00835  Succinic semialdehyde dehydrogenase (SSADH) deficiency
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Carbohydrate metabolism
   00650 Butanoate metabolism
    K00139  ALDH5A1; succinate-semialdehyde dehydrogenase
  Amino acid metabolism
   00250 Alanine, aspartate and glutamate metabolism
    K00139  ALDH5A1; succinate-semialdehyde dehydrogenase
KEGG modules [BR:ko00002]
 Pathway module
  Nucleotide and amino acid metabolism
   Other amino acid metabolism
    M00027  GABA (gamma-Aminobutyrate) shunt
     K00139  ALDH5A1; succinate-semialdehyde dehydrogenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.1  With NAD+ or NADP+ as acceptor
    1.2.1.24  succinate-semialdehyde dehydrogenase (NAD+)
     K00139  ALDH5A1; succinate-semialdehyde dehydrogenase
BRITE hierarchy
Other DBs
RN: R00713
GO: 0004777
Genes
HSA: 7915(ALDH5A1)
PTR: 449515(ALDH5A1)
PPS: 100973567(ALDH5A1)
PON: 100458767(ALDH5A1)
NLE: 100598672(ALDH5A1)
MCC: 707902(ALDH5A1)
MCF: 102126652(ALDH5A1)
CSAB: 103222054(ALDH5A1)
RRO: 104663880(ALDH5A1)
RBB: 108533666(ALDH5A1)
CJC: 100411976(ALDH5A1)
SBQ: 101032615(ALDH5A1)
MMU: 214579(Aldh5a1)
RNO: 291133(Aldh5a1)
CGE: 100764462(Aldh5a1)
NGI: 103745192(Aldh5a1)
HGL: 101723101(Aldh5a1)
OCU: 100351836(ALDH5A1)
TUP: 102502332(ALDH5A1)
CFA: 488246(ALDH5A1)
AML: 100484592(ALDH5A1)
UMR: 103665177(ALDH5A1)
ORO: 101383029(ALDH5A1)
FCA: 101088238(ALDH5A1)
PTG: 102964382(ALDH5A1)
AJU: 106968435(ALDH5A1)
BTA: 532724(ALDH5A1)
BOM: 106701204(ALDH5A1)
BIU: 109577165(ALDH5A1)
PHD: 102339891(ALDH5A1)
CHX: 102169437(ALDH5A1)
OAS: 101107828(ALDH5A1)
SSC: 100157072(ALDH5A1)
CFR: 102518028(ALDH5A1)
CDK: 105089130(ALDH5A1)
BACU: 103016976(ALDH5A1)
LVE: 103088365(ALDH5A1)
OOR: 101288482(ALDH5A1)
ECB: 100067559(ALDH5A1)
EPZ: 103546699(ALDH5A1)
EAI: 106822356(ALDH5A1)
MYB: 102260777(ALDH5A1)
MYD: 102753126(ALDH5A1)
HAI: 109396396(ALDH5A1)
RSS: 109437529(ALDH5A1)
PALE: 102896629(ALDH5A1)
LAV: 100665909(ALDH5A1)
TMU: 101343803
MDO: 100024272(ALDH5A1)
SHR: 100931547(ALDH5A1)
GGA: 420818(ALDH5A1)
MGP: 100546241(ALDH5A1)
CJO: 107309742(ALDH5A1)
APLA: 101793939(ALDH5A1)
ACYG: 106038363(ALDH5A1)
TGU: 100222151(ALDH5A1)
GFR: 102039068(ALDH5A1)
FAB: 101808132(ALDH5A1)
PHI: 102114491(ALDH5A1)
PMAJ: 107215792(ALDH5A1)
CCW: 104691447(ALDH5A1)
FPG: 101913385(ALDH5A1)
FCH: 102046638(ALDH5A1)
CLV: 102091200(ALDH5A1)
EGZ: 104125447(ALDH5A1)
AAM: 106483255(ALDH5A1)
ASN: 102378246(ALDH5A1)
AMJ: 102577046(ALDH5A1)
PSS: 102449242(ALDH5A1)
CMY: 102931386(ALDH5A1)
CPIC: 101945488(ALDH5A1)
ACS: 100567651(aldh5a1)
PVT: 110072879(ALDH5A1)
PBI: 103063078(ALDH5A1)
GJA: 107113410(ALDH5A1)
XLA: 108719155(aldh5a1.L) 108720127(aldh5a1.S)
XTR: 100216127(aldh5a1)
NPR: 108792900(ALDH5A1)
DRE: 565235(aldh5a1)
CCAR: 109106577
IPU: 108270702(aldh5a1)
AMEX: 103033070(aldh5a1)
TRU: 101064243(aldh5a1)
LCO: 104933853(aldh5a1)
NCC: 104948663(aldh5a1)
MZE: 101464303(aldh5a1)
OLA: 101159164(aldh5a1)
XMA: 102225683(aldh5a1)
PRET: 103477483(aldh5a1)
NFU: 107379020(aldh5a1)
CSEM: 103388970(aldh5a1)
HCQ: 109512139(aldh5a1)
BPEC: 110157886(aldh5a1)
SASA: 106605473(SSDH)
ELS: 105019234(aldh5a1)
SFM: 108940701(aldh5a1)
LCM: 102345816(ALDH5A1)
CMK: 103184917(aldh5a1)
SPU: 584281
APLC: 110989753
SKO: 100367735
DME: Dmel_CG4685(Ssadh)
DSI: Dsimw501_GD18186(Dsim_GD18186)
MDE: 101900308
AAG: 5565255
AME: 412305(Ssadh)
BIM: 100750149
BTER: 100648985
SOC: 105200884
AEC: 105143617
ACEP: 105620176
PBAR: 105430507
HST: 105186718
CFO: 105255355
LHU: 105674093
PGC: 109854973
NVI: 100117954
TCA: 661308
NVL: 108567416
BMOR: 101744102
PMAC: 106714089
PRAP: 110993252
PXY: 105392542
API: 100160792
DNX: 107173419
ZNE: 110831901
TUT: 107371700
CEL: CELE_F45H10.1(alh-7)
CBR: CBG20774(Cbr-alh-7)
BMY: Bm1_35520
TSP: Tsp_07602
MYI: 110455008
OBI: 106879957
SHX: MS3_09350
ADF: 107331082
HMG: 100208673
 » show all
TaxonomyKoalaUniProt
Reference
PMID:7814412
  Authors
Chambliss KL, Caudle DL, Hinson DD, Moomaw CR, Slaughter CA, Jakobs C, Gibson KM
  Title
Molecular cloning of the mature NAD(+)-dependent succinic semialdehyde dehydrogenase from rat and human. cDNA isolation, evolutionary homology, and tissue expression.
  Journal
J Biol Chem 270:461-7 (1995)
DOI:10.1074/jbc.270.1.461

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