KEGG   ORTHOLOGY: K00139Help
Entry
K00139                      KO                                     

Name
ALDH5A1
Definition
succinate-semialdehyde dehydrogenase [EC:1.2.1.24]
Pathway
Alanine, aspartate and glutamate metabolism
Butanoate metabolism
Metabolic pathways
Microbial metabolism in diverse environments
Module
M00027  
GABA (gamma-Aminobutyrate) shunt
Disease
H00835  
Succinic semialdehyde dehydrogenase (SSADH) deficiency
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Carbohydrate metabolism
   00650 Butanoate metabolism
    K00139  ALDH5A1; succinate-semialdehyde dehydrogenase
  Amino acid metabolism
   00250 Alanine, aspartate and glutamate metabolism
    K00139  ALDH5A1; succinate-semialdehyde dehydrogenase
KEGG modules [BR:ko00002]
 Pathway module
  Nucleotide and amino acid metabolism
   Other amino acid metabolism
    M00027  GABA (gamma-Aminobutyrate) shunt
     K00139  ALDH5A1; succinate-semialdehyde dehydrogenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.1  With NAD+ or NADP+ as acceptor
    1.2.1.24  succinate-semialdehyde dehydrogenase (NAD+)
     K00139  ALDH5A1; succinate-semialdehyde dehydrogenase
BRITE hierarchy
Other DBs
RN: 
GO: 
Genes
HSA: 
7915(ALDH5A1)
PTR: 
449515(ALDH5A1)
PPS: 
100973567(ALDH5A1)
PON: 
100458767(ALDH5A1)
NLE: 
100598672(ALDH5A1)
MCC: 
707902(ALDH5A1)
MCF: 
102126652(ALDH5A1)
CSAB: 
103222054(ALDH5A1)
RRO: 
104663880(ALDH5A1)
RBB: 
108533666(ALDH5A1)
CJC: 
100411976(ALDH5A1)
SBQ: 
101032615(ALDH5A1)
MMU: 
214579(Aldh5a1)
RNO: 
291133(Aldh5a1)
CGE: 
100764462(Aldh5a1)
NGI: 
103745192(Aldh5a1)
HGL: 
101723101(Aldh5a1)
CCAN: 
OCU: 
100351836(ALDH5A1)
TUP: 
102502332(ALDH5A1)
CFA: 
488246(ALDH5A1)
AML: 
100484592(ALDH5A1)
UMR: 
103665177(ALDH5A1)
FCA: 
101088238(ALDH5A1)
PTG: 
102964382(ALDH5A1)
AJU: 
106968435(ALDH5A1)
BTA: 
532724(ALDH5A1)
BOM: 
106701204(ALDH5A1)
BIU: 
109577165(ALDH5A1)
PHD: 
102339891(ALDH5A1)
CHX: 
102169437(ALDH5A1)
OAS: 
101107828(ALDH5A1)
SSC: 
100157072(ALDH5A1)
CFR: 
102518028(ALDH5A1)
CDK: 
105089130(ALDH5A1)
BACU: 
103016976(ALDH5A1)
LVE: 
103088365(ALDH5A1)
ECB: 
100067559(ALDH5A1)
EPZ: 
103546699(ALDH5A1)
EAI: 
106822356(ALDH5A1)
MYB: 
102260777(ALDH5A1)
MYD: 
102753126(ALDH5A1)
HAI: 
109396396(ALDH5A1)
RSS: 
109437529(ALDH5A1)
PALE: 
102896629(ALDH5A1)
LAV: 
100665909(ALDH5A1)
MDO: 
100024272(ALDH5A1)
SHR: 
100931547(ALDH5A1)
GGA: 
420818(ALDH5A1)
MGP: 
100546241(ALDH5A1)
CJO: 
107309742(ALDH5A1)
APLA: 
101793939(ALDH5A1)
ACYG: 
106038363(ALDH5A1)
TGU: 
100222151(ALDH5A1)
GFR: 
102039068(ALDH5A1)
FAB: 
101808132(ALDH5A1)
PHI: 
102114491(ALDH5A1)
PMAJ: 
107215792(ALDH5A1)
CCW: 
104691447(ALDH5A1)
FPG: 
101913385(ALDH5A1)
FCH: 
102046638(ALDH5A1)
CLV: 
102091200(ALDH5A1)
AAM: 
106483255(ALDH5A1)
ASN: 
102378246(ALDH5A1)
AMJ: 
102577046(ALDH5A1)
PSS: 
102449242(ALDH5A1)
CMY: 
102931386(ALDH5A1)
CPIC: 
101945488(ALDH5A1)
ACS: 
100567651(aldh5a1)
PVT: 
110072879(ALDH5A1)
PBI: 
103063078(ALDH5A1)
GJA: 
107113410(ALDH5A1)
XLA: 
108719155(aldh5a1.L) 108720127(aldh5a1.S)
XTR: 
100216127(aldh5a1)
NPR: 
108792900(ALDH5A1)
DRE: 
565235(aldh5a1)
SRX: 
SANH: 
SGH: 
IPU: 
108270702(aldh5a1)
AMEX: 
103033070(aldh5a1)
TRU: 
101064243(aldh5a1)
TNG: 
LCO: 
104933853(aldh5a1)
NCC: 
104948663(aldh5a1)
MZE: 
101464303(aldh5a1)
OLA: 
101159164(aldh5a1)
XMA: 
102225683(aldh5a1)
CSEM: 
103388970(aldh5a1)
LCF: 
HCQ: 
109512139(aldh5a1)
BPEC: 
110157886(aldh5a1)
SASA: 
106605473(SSDH)
ELS: 
105019234(aldh5a1)
SFM: 
108940701(aldh5a1)
LCM: 
102345816(ALDH5A1)
CMK: 
103184917(aldh5a1)
BFO: 
CIN: 
SPU: 
APLC: 
SKO: 
DME: 
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
Dsimw501_GD18186(Dsim_GD18186)
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
MDE: 
AGA: 
AAG: 
CQU: 
AME: 
412305(Ssadh)
BIM: 
BTER: 
SOC: 
AEC: 
ACEP: 
PBAR: 
HST: 
CFO: 
LHU: 
PGC: 
NVI: 
TCA: 
NVL: 
BMOR: 
DPL: 
PXY: 
API: 
DNX: 
PHU: 
FCD: 
DPX: 
ISC: 
TUT: 
CEL: 
CBR: 
CBG20774(Cbr-alh-7)
NAI: 
BMY: 
LOA: 
TSP: 
HRO: 
LGI: 
CRG: 
OBI: 
LAK: 
SMM: 
SHX: 
NVE: 
ADF: 
HMG: 
AFM: 
 » show all
TaxonomyKoalaUniProt
Reference
PMID:7814412
  Authors
Chambliss KL, Caudle DL, Hinson DD, Moomaw CR, Slaughter CA, Jakobs C, Gibson KM
  Title
Molecular cloning of the mature NAD(+)-dependent succinic semialdehyde dehydrogenase from rat and human. cDNA isolation, evolutionary homology, and tissue expression.
  Journal
J Biol Chem 270:461-7 (1995)
DOI:10.1074/jbc.270.1.461

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