KEGG   ORTHOLOGY: K00665Help
Entry
K00665                      KO                                     

Name
FASN
Definition
fatty acid synthase, animal type [EC:2.3.1.85]
Pathway
ko00061  Fatty acid biosynthesis
ko01100  Metabolic pathways
ko01212  Fatty acid metabolism
ko04152  AMPK signaling pathway
ko04910  Insulin signaling pathway
Module
M00082  Fatty acid biosynthesis, initiation
M00083  Fatty acid biosynthesis, elongation
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Lipid metabolism
   00061 Fatty acid biosynthesis
    K00665  FASN; fatty acid synthase, animal type
 Environmental Information Processing
  Signal transduction
   04152 AMPK signaling pathway
    K00665  FASN; fatty acid synthase, animal type
 Organismal Systems
  Endocrine system
   04910 Insulin signaling pathway
    K00665  FASN; fatty acid synthase, animal type
KEGG modules [BR:ko00002]
 Pathway module
  Carbohydrate and lipid metabolism
   Fatty acid metabolism
    M00082  Fatty acid biosynthesis, initiation
     K00665  FASN; fatty acid synthase, animal type
    M00083  Fatty acid biosynthesis, elongation
     K00665  FASN; fatty acid synthase, animal type
Enzymes [BR:ko01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.85  fatty-acid synthase
     K00665  FASN; fatty acid synthase, animal type
Lipid biosynthesis proteins [BR:ko01004]
 Fatty acid synthase
  Animal type
   K00665  FASN; fatty acid synthase, animal type
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   K00665  FASN; fatty acid synthase, animal type
  Exosomal proteins of breast milk
   K00665  FASN; fatty acid synthase, animal type
  Exosomal proteins of colorectal cancer cells
   K00665  FASN; fatty acid synthase, animal type
  Exosomal proteins of bladder cancer cells
   K00665  FASN; fatty acid synthase, animal type
BRITE hierarchy
Other DBs
RN: R01404 R01624 R01626 R01706 R04355 R04428 R04430 R04533 R04534 R04535 R04536 R04537 R04543 R04544 R04566 R04568 R04725 R04726 R04952 R04953 R04954 R04956 R04957 R04959 R04960 R04962 R04963 R04965 R04967 R04968 R04970 R08159
GO: 0004312
Genes
HSA: 2194(FASN)
PTR: 454986(FASN)
PPS: 100985873(FASN)
GGO: 101151060(FASN)
PON: 100456558(FASN)
NLE: 100596750 100597701(FASN)
MCC: 715708(FASN)
MCF: 102119674(FASN)
CSAB: 103243754(FASN)
RRO: 104654984(FASN)
RBB: 108525064 108534089(FASN)
CJC: 100402953(FASN)
SBQ: 101045175(FASN)
MMU: 14104(Fasn)
RNO: 50671(Fasn)
CGE: 100689207(Fasn)
NGI: 103730050(Fasn)
HGL: 101698314(Fasn)
CCAN: 109702407(Fasn)
TUP: 102481635(FASN)
CFA: 483378(FASN)
AML: 100468470(FASN)
UMR: 103666012(FASN)
ORO: 101372296(FASN)
FCA: 100270775(FASN)
PTG: 102956933(FASN)
AJU: 106986313(FASN)
BTA: 281152(FASN)
BOM: 102278267(FASN)
BIU: 109573330(FASN)
PHD: 102336161(FASN)
CHX: 100861286(FASN)
OAS: 100170327(FASN)
SSC: 397561(FASN)
CFR: 102509439(FASN)
CDK: 105102220(FASN)
BACU: 103017465
LVE: 103077747(FASN)
OOR: 101279575(FASN)
ECB: 100057311(FASN)
EPZ: 103545808 103551124(FASN)
EAI: 106846150
MYB: 102251003(FASN)
MYD: 102761714(FASN)
HAI: 109393056(FASN)
RSS: 109449422(FASN)
PALE: 102887167(FASN)
LAV: 100674176(FASN)
TMU: 101361851
MDO: 100025176(FASN)
SHR: 100924144(FASN)
OAA: 100091954
GGA: 396061(FASN)
MGP: 100542651(FASN)
CJO: 107322058(FASN)
APLA: 101796973(FASN)
ACYG: 106046771(FASN)
TGU: 100226957(FASN)
GFR: 102043163(FASN)
FAB: 101820764(FASN)
PHI: 102102393(FASN)
PMAJ: 107212310(FASN)
CCW: 104698180(FASN)
FPG: 101924649(FASN)
FCH: 102046127(FASN)
CLV: 102086015(FASN)
EGZ: 104131108(FASN)
AAM: 106487141(FASN)
ASN: 102384493(FASN)
AMJ: 102571811(FASN)
PSS: 102458578(FASN)
CMY: 102933656(FASN)
CPIC: 101942965(FASN)
ACS: 100563002(fasn)
PVT: 110090820(FASN)
PBI: 103062560(FASN)
GJA: 107118129(FASN)
XLA: 108701000
XTR: 100487052(fasn)
NPR: 108791330(FASN)
DRE: 559001(fasn)
SRX: 107722180 107755500(fasn)
IPU: 108273998(fasn)
AMEX: 103030617(fasn)
TRU: 101069108(fasn) 105418859
LCO: 104927028(fasn)
MZE: 101485706
OLA: 101171365(fasn)
XMA: 102232393(fasn)
PRET: 103482177(fasn)
NFU: 107396699(fasn)
CSEM: 103381833(fasn)
HCQ: 109513269(fasn)
BPEC: 110154166(fasn)
ELS: 105021150(fasn)
SFM: 108939982(fasn)
LCM: 102352909(FASN)
CMK: 103175468(fasn)
CIN: 100181277
SPU: 105440011
DME: Dmel_CG17374(FASN3) Dmel_CG3523(FASN1) Dmel_CG3524(FASN2)
DSI: Dsimw501_GD17693(Dsim_GD17693) Dsimw501_GD23206(Dsim_GD23206) Dsimw501_GD23207(Dsim_GD23207)
AME: 411959(GB16883) 412815
CEL: CELE_F32H2.5(fasn-1)
CBR: CBG12408(Cbr-fasn-1)
BMY: Bm1_35180
TSP: Tsp_06638
EPA: 110240069
ADF: 107350794
 » show all
TaxonomyKoalaUniProt
Reference
PMID:2717611
  Authors
Amy CM, Witkowski A, Naggert J, Williams B, Randhawa Z, Smith S
  Title
Molecular cloning and sequencing of cDNAs encoding the entire rat fatty acid synthase.
  Journal
Proc Natl Acad Sci U S A 86:3114-8 (1989)
DOI:10.1073/pnas.86.9.3114
  Sequence
[rno:50671]

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