KEGG   ORTHOLOGY: K00718Help
Entry
K00718                      KO                                     

Name
FUT1_2
Definition
galactoside 2-L-fucosyltransferase 1/2 [EC:2.4.1.69]
Pathway
Glycosphingolipid biosynthesis - lacto and neolacto series
Glycosphingolipid biosynthesis - globo series
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Glycan biosynthesis and metabolism
   00601 Glycosphingolipid biosynthesis - lacto and neolacto series
    K00718  FUT1_2; galactoside 2-L-fucosyltransferase 1/2
   00603 Glycosphingolipid biosynthesis - globo series
    K00718  FUT1_2; galactoside 2-L-fucosyltransferase 1/2
Enzymes [BR:ko01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.1  Hexosyltransferases
    2.4.1.69  galactoside 2-alpha-L-fucosyltransferase
     K00718  FUT1_2; galactoside 2-L-fucosyltransferase 1/2
Glycosyltransferases [BR:ko01003]
 Glycan extension
  ABO blood group
   K00718  FUT1_2; galactoside 2-L-fucosyltransferase 1/2
BRITE hierarchy
Other DBs
Genes
HSA: 
2523(FUT1) 2524(FUT2)
PTR: 
468944(FUT2) 468947(FUT1)
PPS: 
100990363(FUT1) 100991035(FUT2)
GGO: 
PON: 
100171991(FUT1) 100445051(FUT2)
MCC: 
718252(FUT1)
MCF: 
MMU: 
14343(Fut1) 14344(Fut2) 56546(Sec1)
RNO: 
308586(Sec1) 58924(Fut2) 81919(Fut1)
CGE: 
100751185(Fut2) 100757047(Fut1)
HGL: 
TUP: 
CFA: 
484396(FUT1) 484398(FUT2)
AML: 
FCA: 
PTG: 
102962287(FUT2) 102969895(FUT1)
BTA: 
281174(FUT1) 281175(FUT2) 281483(SEC1)
BOM: 
PHD: 
CHX: 
SSC: 
100524201(FUT2A) 397138(FUT1) 397139(FUT2)
CFR: 
BACU: 
103015344(FUT1)
LVE: 
103080875(FUT2) 103081703(FUT1)
ECB: 
MYB: 
102257351(FUT1) 102259445(FUT2)
MYD: 
PALE: 
102885708(FUT1) 102886704(FUT2)
MDO: 
SHR: 
100931578(FUT1)
OAA: 
100085980(FUT1) 100681084(FUT2)
ASN: 
AMJ: 
PSS: 
CMY: 
ACS: 
PBI: 
XLA: 
398668(fut1)
XTR: 
CMK: 
AME: 
726095(GB16372)
TCA: 
PHU: 
 » show all
TaxonomyKoalaUniProt
Reference
PMID:2118655
  Authors
Larsen RD, Ernst LK, Nair RP, Lowe JB
  Title
Molecular cloning, sequence, and expression of a human GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase cDNA that can form the H blood group antigen.
  Journal
Proc Natl Acad Sci U S A 87:6674-8 (1990)
Reference
PMID:7876235
  Authors
Kelly RJ, Rouquier S, Giorgi D, Lennon GG, Lowe JB
  Title
Sequence and expression of a candidate for the human Secretor blood group alpha(1,2)fucosyltransferase gene (FUT2). Homozygosity for an enzyme-inactivating nonsense mutation commonly correlates with the non-secretor phenotype.
  Journal
J Biol Chem 270:4640-9 (1995)

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