KEGG   ORTHOLOGY: K02366Help
Entry
K02366                      KO                                     

Name
EXT1
Definition
glucuronyl/N-acetylglucosaminyl transferase EXT1 [EC:2.4.1.224 2.4.1.225]
Pathway
Glycosaminoglycan biosynthesis - heparan sulfate / heparin
Module
M00059  
Glycosaminoglycan biosynthesis, heparan sulfate backbone
Disease
H00122  
Multiple exostoses
H00493  
Heparan sulfate proteoglycan gene defects
H00977  
Trichorhinophalangeal dysplasia
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Glycan biosynthesis and metabolism
   00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin
    K02366  EXT1; glucuronyl/N-acetylglucosaminyl transferase EXT1
KEGG modules [BR:ko00002]
 Pathway module
  Carbohydrate and lipid metabolism
   Glycosaminoglycan metabolism
    M00059  Glycosaminoglycan biosynthesis, heparan sulfate backbone
     K02366  EXT1; glucuronyl/N-acetylglucosaminyl transferase EXT1
Enzymes [BR:ko01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.1  Hexosyltransferases
    2.4.1.224  glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase
     K02366  EXT1; glucuronyl/N-acetylglucosaminyl transferase EXT1
    2.4.1.225  N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase
     K02366  EXT1; glucuronyl/N-acetylglucosaminyl transferase EXT1
Glycosyltransferases [BR:ko01003]
 Glycan extension
  O-Glycan
   K02366  EXT1; glucuronyl/N-acetylglucosaminyl transferase EXT1
BRITE hierarchy
Other DBs
Genes
HSA: 
2131(EXT1)
PTR: 
464349(EXT1)
PPS: 
100985695(EXT1)
GGO: 
101133078(EXT1)
PON: 
100172450(EXT1)
MCC: 
701488(EXT1)
MCF: 
MMU: 
14042(Ext1)
RNO: 
299907(Ext1)
CGE: 
100689334(Ext1)
HGL: 
101706257(Ext1)
TUP: 
102467803(EXT1)
CFA: 
482024(EXT1)
AML: 
FCA: 
101081362(EXT1)
PTG: 
102968916(EXT1)
BTA: 
538602(EXT1)
BOM: 
102280308(EXT1)
PHD: 
102335726(EXT1)
CHX: 
102182809(EXT1)
SSC: 
100157655(EXT1)
CFR: 
102508456(EXT1)
ECB: 
100056983(EXT1)
MYB: 
102244714(EXT1)
MYD: 
102765321(EXT1)
PALE: 
MDO: 
100025396(EXT1)
SHR: 
100929895(EXT1)
OAA: 
100078206(EXT1)
GGA: 
MGP: 
TGU: 
100227900(EXT1)
FAB: 
PHI: 
APLA: 
FPG: 
FCH: 
CLV: 
ASN: 
PSS: 
102444477(EXT1)
CMY: 
ACS: 
XLA: 
399115(ext1)
XTR: 
448393(ext1)
DRE: 
497279(ext1a) 497280(ext1b) 497281(ext1c)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
BFO: 
CIN: 
SPU: 
DME: 
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
AGA: 
AAG: 
CQU: 
AME: 
408293(ttv)
NVI: 
TCA: 
BMOR: 
PHU: 
ISC: 
CEL: 
CBR: 
CBG06125(Cbr-rib-1)
BMY: 
LOA: 
TSP: 
SMM: 
NVE: 
HMG: 
TAD: 
AQU: 
GMX: 
SMO: 
PPP: 
GSL: 
ACAN: 
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