KEGG   ORTHOLOGY: K04135Help
Entry
K04135                      KO                                     

Name
ADRA1A
Definition
adrenergic receptor alpha-1A
Pathway
Calcium signaling pathway
cGMP-PKG signaling pathway
Neuroactive ligand-receptor interaction
AMPK signaling pathway
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Salivary secretion
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04020 Calcium signaling pathway
    K04135  ADRA1A; adrenergic receptor alpha-1A
   04022 cGMP - PKG signaling pathway
    K04135  ADRA1A; adrenergic receptor alpha-1A
   04152 AMPK signaling pathway
    K04135  ADRA1A; adrenergic receptor alpha-1A
  Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K04135  ADRA1A; adrenergic receptor alpha-1A
 Organismal Systems
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    K04135  ADRA1A; adrenergic receptor alpha-1A
   04270 Vascular smooth muscle contraction
    K04135  ADRA1A; adrenergic receptor alpha-1A
  Digestive system
   04970 Salivary secretion
    K04135  ADRA1A; adrenergic receptor alpha-1A
G protein-coupled receptors [BR:ko04030]
 Class A. Rhodopsin family
  Biogenic amine
   Adrenaline [OT]
    K04135  ADRA1A; adrenergic receptor alpha-1A
BRITE hierarchy
Other DBs
Genes
HSA: 
148(ADRA1A)
PTR: 
472723(ADRA1A)
PPS: 
100986808(ADRA1A)
GGO: 
101132819(ADRA1A)
PON: 
100447956(ADRA1A)
NLE: 
100584192(ADRA1A)
MCC: 
712509(ADRA1A)
MCF: 
102126453(ADRA1A)
CSAB: 
103215521(ADRA1A)
RRO: 
104673950(ADRA1A)
RBB: 
108537638(ADRA1A)
CJC: 
100406276(ADRA1A)
SBQ: 
101030040(ADRA1A)
MMU: 
11549(Adra1a)
RNO: 
29412(Adra1a)
CGE: 
100758859(Adra1a)
NGI: 
103732394(Adra1a)
HGL: 
101712485(Adra1a)
CCAN: 
OCU: 
100009237(ADRA1A)
TUP: 
102485037(ADRA1A)
CFA: 
403866(ADRA1A)
AML: 
100479899(ADRA1A)
UMR: 
103673285(ADRA1A)
FCA: 
101098375(ADRA1A)
PTG: 
102958979(ADRA1A)
AJU: 
106966540(ADRA1A)
BTA: 
282134(ADRA1A)
BOM: 
102265630(ADRA1A)
BIU: 
109563154(ADRA1A)
PHD: 
102324768(ADRA1A)
CHX: 
102182788(ADRA1A)
OAS: 
100169940(ADRA1A)
SSC: 
100144471(ADRA1A)
CFR: 
102516168(ADRA1A)
CDK: 
105102306(ADRA1A)
BACU: 
103018651(ADRA1A)
LVE: 
103084741(ADRA1A)
ECB: 
100054461(ADRA1A)
EPZ: 
103561082(ADRA1A)
EAI: 
106834008(ADRA1A)
MYB: 
102249717(ADRA1A)
MYD: 
102767266(ADRA1A)
HAI: 
109391742(ADRA1A)
RSS: 
109436442(ADRA1A)
PALE: 
102884516(ADRA1A)
LAV: 
100668259(ADRA1A)
MDO: 
100017802(ADRA1A)
SHR: 
100931456(ADRA1A)
OAA: 
100680572(ADRA1A)
GGA: 
428203(ADRA1A)
MGP: 
100551391(ADRA1A)
CJO: 
107323705(ADRA1A)
APLA: 
101791607(ADRA1A)
ACYG: 
106046252(ADRA1A)
TGU: 
100227070(ADRA1A)
GFR: 
102044365(ADRA1A)
FAB: 
101813194(ADRA1A)
PHI: 
102108110(ADRA1A)
PMAJ: 
107213797(ADRA1A)
CCW: 
104694822(ADRA1A)
FPG: 
101923570(ADRA1A)
FCH: 
102049705(ADRA1A)
CLV: 
102094627(ADRA1A)
AAM: 
106494221(ADRA1A)
ASN: 
AMJ: 
102557676(ADRA1A)
PSS: 
102445281(ADRA1A)
CMY: 
102933280(ADRA1A)
CPIC: 
101931917(ADRA1A)
ACS: 
100554316(adra1a)
PVT: 
PBI: 
103048676(ADRA1A)
GJA: 
XLA: 
XTR: 
100492776(adra1a)
NPR: 
DRE: 
557259(adra1ab) 798498(adra1aa)
SRX: 
SANH: 
SGH: 
IPU: 
AMEX: 
TRU: 
TNG: 
LCO: 
NCC: 
MZE: 
OLA: 
XMA: 
CSEM: 
LCF: 
HCQ: 
BPEC: 
SASA: 
ELS: 
SFM: 
LCM: 
CMK: 
103191393(adra1a)
APLC: 
SKO: 
DNX: 
FCD: 
HRO: 
LGI: 
CRG: 
MYI: 
SMM: 
EPA: 
ADF: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Docherty JR
  Title
Subtypes of functional alpha1-adrenoceptor.
  Journal
Cell Mol Life Sci 67:405-17 (2010)
DOI:10.1007/s00018-009-0174-4
Reference
  Authors
Wright CD, Wu SC, Dahl EF, Sazama AJ, O'Connell TD
  Title
Nuclear localization drives alpha1-adrenergic receptor oligomerization and signaling in cardiac myocytes.
  Journal
Cell Signal 24:794-802 (2012)
DOI:10.1016/j.cellsig.2011.11.014
  Sequence
[hsa:148]

KEGG   ORTHOLOGY: K04136Help
Entry
K04136                      KO                                     

Name
ADRA1B
Definition
adrenergic receptor alpha-1B
Pathway
Calcium signaling pathway
cGMP-PKG signaling pathway
Neuroactive ligand-receptor interaction
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Salivary secretion
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04020 Calcium signaling pathway
    K04136  ADRA1B; adrenergic receptor alpha-1B
   04022 cGMP - PKG signaling pathway
    K04136  ADRA1B; adrenergic receptor alpha-1B
  Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K04136  ADRA1B; adrenergic receptor alpha-1B
 Organismal Systems
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    K04136  ADRA1B; adrenergic receptor alpha-1B
   04270 Vascular smooth muscle contraction
    K04136  ADRA1B; adrenergic receptor alpha-1B
  Digestive system
   04970 Salivary secretion
    K04136  ADRA1B; adrenergic receptor alpha-1B
G protein-coupled receptors [BR:ko04030]
 Class A. Rhodopsin family
  Biogenic amine
   Adrenaline [OT]
    K04136  ADRA1B; adrenergic receptor alpha-1B
BRITE hierarchy
Other DBs
Genes
HSA: 
147(ADRA1B)
PTR: 
736934(ADRA1B)
PPS: 
106634821(ADRA1B)
GGO: 
101142001(ADRA1B)
PON: 
100435632(ADRA1B)
NLE: 
100601962(ADRA1B)
MCC: 
695106(ADRA1B)
MCF: 
102126794(ADRA1B)
CSAB: 
103244899(ADRA1B)
RRO: 
104667499(ADRA1B)
RBB: 
108537942(ADRA1B)
CJC: 
100395759(ADRA1B)
SBQ: 
101040811(ADRA1B)
MMU: 
11548(Adra1b)
RNO: 
24173(Adra1b)
CGE: 
103160164(Adra1b)
NGI: 
103724547(Adra1b)
HGL: 
101700459(Adra1b)
CCAN: 
109693948(Adra1b)
OCU: 
100008731(ADRA1B)
TUP: 
102486850(ADRA1B)
CFA: 
403962(ADRA1B)
AML: 
100482658(ADRA1B)
UMR: 
103664794(ADRA1B)
FCA: 
101092238(ADRA1B)
PTG: 
102954633(ADRA1B)
AJU: 
106967619(ADRA1B)
BTA: 
407140(ADRA1B)
BOM: 
102285919(ADRA1B)
BIU: 
109562263(ADRA1B)
PHD: 
102320584(ADRA1B)
CHX: 
102179850(ADRA1B)
OAS: 
101114869(ADRA1B)
SSC: 
100519931(ADRA1B)
CFR: 
102505346(ADRA1B)
CDK: 
105099901(ADRA1B)
BACU: 
103009751(ADRA1B)
LVE: 
103083430(ADRA1B)
ECB: 
100071055(ADRA1B)
EPZ: 
103553004(ADRA1B)
EAI: 
106832140(ADRA1B)
MYB: 
102248047(ADRA1B)
MYD: 
102772976(ADRA1B)
HAI: 
109394203(ADRA1B)
RSS: 
109451954(ADRA1B)
PALE: 
102891192(ADRA1B)
LAV: 
100675999(ADRA1B)
MDO: 
100025515(ADRA1B)
SHR: 
100933002(ADRA1B)
OAA: 
100074819(ADRA1B)
GGA: 
373890(ADRA1B)
MGP: 
100543635(ADRA1B)
CJO: 
107320332(ADRA1B)
APLA: 
101800019(ADRA1B)
ACYG: 
106034421(ADRA1B)
TGU: 
100218481(ADRA1B)
GFR: 
102036518(ADRA1B)
FAB: 
101814297(ADRA1B)
PHI: 
102105127(ADRA1B)
PMAJ: 
107210901(ADRA1B)
CCW: 
104689636(ADRA1B)
FPG: 
101920857(ADRA1B)
FCH: 
102047141(ADRA1B)
CLV: 
102097753(ADRA1B)
AAM: 
106493600(ADRA1B)
ASN: 
102372292(ADRA1B)
AMJ: 
102565786(ADRA1B)
PSS: 
102461525(ADRA1B)
CMY: 
102933636(ADRA1B)
CPIC: 
101947598(ADRA1B)
XLA: 
108710187(adra1b.L) 108712448(adra1b.S)
XTR: 
100488806(adra1b)
NPR: 
108788121(ADRA1B)
DRE: 
100149100(adra1ba) 492486(adra1bb)
SRX: 
SANH: 
SGH: 
IPU: 
AMEX: 
103033427(adra1b)
TRU: 
TNG: 
LCO: 
NCC: 
MZE: 
OLA: 
XMA: 
CSEM: 
LCF: 
HCQ: 
BPEC: 
SASA: 
ELS: 
SFM: 
LCM: 
102367148(ADRA1B)
CMK: 
103186484(adra1b)
BFO: 
SPU: 
APLC: 
DPA: 
FCD: 
DPX: 
CRG: 
ADF: 
TAD: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Docherty JR
  Title
Subtypes of functional alpha1-adrenoceptor.
  Journal
Cell Mol Life Sci 67:405-17 (2010)
DOI:10.1007/s00018-009-0174-4
Reference
  Authors
Wright CD, Wu SC, Dahl EF, Sazama AJ, O'Connell TD
  Title
Nuclear localization drives alpha1-adrenergic receptor oligomerization and signaling in cardiac myocytes.
  Journal
Cell Signal 24:794-802 (2012)
DOI:10.1016/j.cellsig.2011.11.014
  Sequence
[hsa:147]

KEGG   ORTHOLOGY: K04138Help
Entry
K04138                      KO                                     

Name
ADRA2A
Definition
adrenergic receptor alpha-2A
Pathway
cGMP-PKG signaling pathway
Neuroactive ligand-receptor interaction
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04022 cGMP - PKG signaling pathway
    K04138  ADRA2A; adrenergic receptor alpha-2A
  Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K04138  ADRA2A; adrenergic receptor alpha-2A
G protein-coupled receptors [BR:ko04030]
 Class A. Rhodopsin family
  Biogenic amine
   Adrenaline [OT]
    K04138  ADRA2A; adrenergic receptor alpha-2A
BRITE hierarchy
Other DBs
Genes
HSA: 
150(ADRA2A)
PTR: 
466201(ADRA2A)
PPS: 
100977068(ADRA2A)
GGO: 
101137632(ADRA2A)
PON: 
100459426(ADRA2A)
NLE: 
100586093(ADRA2A)
MCC: 
695684(ADRA2A)
MCF: 
102140075(ADRA2A)
CSAB: 
103216513(ADRA2A)
RRO: 
104667775(ADRA2A)
RBB: 
108538806(ADRA2A)
CJC: 
103796811(ADRA2A)
SBQ: 
101039216(ADRA2A)
MMU: 
11551(Adra2a)
RNO: 
25083(Adra2a)
CGE: 
100768369(Adra2a)
NGI: 
103744368(Adra2a)
HGL: 
101723298(Adra2a)
CCAN: 
109691509(Adra2a)
OCU: 
100009424(ADRA2A)
TUP: 
102480728(ADRA2A)
CFA: 
486888(ADRA2A)
AML: 
100474011(ADRA2A)
UMR: 
103659210(ADRA2A)
FCA: 
664736(ADRA2A)
PTG: 
102948732(ADRA2A)
AJU: 
106984750(ADRA2A)
BTA: 
282135(ADRA2A)
BOM: 
106700799(ADRA2A)
BIU: 
109553206(ADRA2A)
PHD: 
102341851(ADRA2A)
CHX: 
102187024(ADRA2A)
OAS: 
100170317(ADRA2A)
SSC: 
399501(ADRA2A)
CFR: 
102504908(ADRA2A)
CDK: 
105091698(ADRA2A)
BACU: 
103002174(ADRA2A)
LVE: 
103085955(ADRA2A)
ECB: 
100147119(ADRA2A)
EPZ: 
103564806(ADRA2A)
EAI: 
106837560(ADRA2A)
MYB: 
102259526(ADRA2A)
MYD: 
102773898(ADRA2A)
HAI: 
109384879(ADRA2A)
RSS: 
109444046(ADRA2A)
PALE: 
102881586(ADRA2A)
LAV: 
100672320(ADRA2A)
MDO: 
100027878(ADRA2A)
SHR: 
100929353(ADRA2A)
GGA: 
428980(ADRA2A)
MGP: 
104912010(ADRA2A)
CJO: 
107316160(ADRA2A)
APLA: 
101799674(ADRA2B) 101803955(ADRA2A)
ACYG: 
106031884(ADRA2A)
TGU: 
100231407(ADRA2A)
GFR: 
FAB: 
101809602(ADRA2A)
PHI: 
102109587(ADRA2A)
PMAJ: 
107206514(ADRA2A)
CCW: 
104695286(ADRA2A)
FPG: 
101913158(ADRA2A)
FCH: 
102053594(ADRA2A)
CLV: 
102090898(ADRA2A)
AAM: 
106488367(ADRA2A)
ASN: 
102376693(ADRA2A)
AMJ: 
102576082(ADRA2A)
PSS: 
102463694(ADRA2A)
CMY: 
102938232(ADRA2A)
CPIC: 
101932100(ADRA2A)
ACS: 
PVT: 
110071962(ADRA2A)
PBI: 
GJA: 
XLA: 
XTR: 
NPR: 
108791938(ADRA2A)
DRE: 
266750(adra2a)
SRX: 
SANH: 
SGH: 
IPU: 
108259429(adra2a)
AMEX: 
103035996(adra2a)
TRU: 
101064972(a2a1ar)
TNG: 
LCO: 
NCC: 
MZE: 
OLA: 
XMA: 
CSEM: 
LCF: 
HCQ: 
BPEC: 
SASA: 
ELS: 
105012128(adra2a)
SFM: 
LCM: 
102348663(ADRA2A)
CMK: 
103185246(adra2a)
BFO: 
NAI: 
MYI: 
 » show all
TaxonomyKoalaUniProt
Reference
PMID:9227000
  Authors
MacDonald E, Kobilka BK, Scheinin M
  Title
Gene targeting--homing in on alpha 2-adrenoceptor-subtype function.
  Journal
Trends Pharmacol Sci 18:211-9 (1997)
DOI:10.1016/S0165-6147(97)01063-8
  Sequence
[hsa:150]

KEGG   ORTHOLOGY: K04139Help
Entry
K04139                      KO                                     

Name
ADRA2B
Definition
adrenergic receptor alpha-2B
Pathway
cGMP-PKG signaling pathway
Neuroactive ligand-receptor interaction
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04022 cGMP - PKG signaling pathway
    K04139  ADRA2B; adrenergic receptor alpha-2B
  Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K04139  ADRA2B; adrenergic receptor alpha-2B
G protein-coupled receptors [BR:ko04030]
 Class A. Rhodopsin family
  Biogenic amine
   Adrenaline [OT]
    K04139  ADRA2B; adrenergic receptor alpha-2B
BRITE hierarchy
Other DBs
Genes
HSA: 
151(ADRA2B)
PTR: 
100614466(ADRA2B)
PPS: 
100974246(ADRA2B)
GGO: 
101150045(ADRA2B)
PON: 
100441129(ADRA2B)
NLE: 
100599451(ADRA2B)
MCC: 
694825(ADRA2B)
MCF: 
102116265(ADRA2B)
CSAB: 
103241060(ADRA2B)
RRO: 
104661450(ADRA2B)
RBB: 
108520938(ADRA2B)
CJC: 
100412057(ADRA2B)
SBQ: 
101054037(ADRA2B)
MMU: 
11552(Adra2b)
RNO: 
24174(Adra2b)
CGE: 
100757384(Adra2b)
NGI: 
103738289(Adra2b)
HGL: 
101701692(Adra2b)
CCAN: 
109699320(Adra2b)
OCU: 
100352237(ADRA2B)
TUP: 
102497260(ADRA2B)
CFA: 
100855976(ADRA2B)
AML: 
100478006(ADRA2B)
UMR: 
103671879(ADRA2B)
FCA: 
101090432(ADRA2B)
PTG: 
102963560(ADRA2B)
AJU: 
106976045(ADRA2B)
BTA: 
516422(ADRA2B)
BOM: 
102282250(ADRA2B)
BIU: 
109565740(ADRA2B)
PHD: 
102315592(ADRA2B)
CHX: 
102175860(ADRA2B)
OAS: 
100170318(ADRA2B)
SSC: 
641353(ADRA2B)
CFR: 
102507302(ADRA2B)
CDK: 
105092851(ADRA2B)
BACU: 
103021056(ADRA2B)
LVE: 
103090019(ADRA2B)
ECB: 
100051684(ADRA2B)
EPZ: 
103564055(ADRA2B)
EAI: 
106845800(ADRA2B)
MYB: 
102251180(ADRA2B)
MYD: 
102761105(ADRA2B)
HAI: 
109392022(ADRA2B)
RSS: 
109444474(ADRA2B)
PALE: 
102887994(ADRA2B)
LAV: 
100662430(ADRA2B)
MDO: 
100033192(ADRA2B)
SHR: 
100926877(ADRA2B)
OAA: 
100084448(ADRA2B)
GGA: 
101751513(ADRA2B) 426044(ELMOD3)
MGP: 
104917109(ADRA2B)
CJO: 
107323642(ADRA2B)
ACYG: 
106048889(ADRA2B)
FPG: 
101922013(ADRA2B)
AAM: 
106493814(ADRA2B)
ASN: 
102369411(ADRA2B)
AMJ: 
102576495(ADRA2B)
PSS: 
102455491(ADRA2B)
CMY: 
102947396(ADRA2B)
CPIC: 
101947916(ADRA2B)
ACS: 
PVT: 
110072120(ADRA2B)
PBI: 
103057124(ADRA2B)
GJA: 
107106751(ADRA2B)
XLA: 
108711557(adra2b.L) 108712457(adra2b.S)
XTR: 
100485811(adra2b)
NPR: 
108797682(ADRA2B)
DRE: 
SRX: 
SANH: 
SGH: 
IPU: 
AMEX: 
TRU: 
TNG: 
LCO: 
NCC: 
MZE: 
OLA: 
XMA: 
CSEM: 
LCF: 
HCQ: 
BPEC: 
SASA: 
ELS: 
SFM: 
LCM: 
CMK: 
103187772(adra2b)
BFO: 
CIN: 
LAK: 
OVI: 
 » show all
TaxonomyKoalaUniProt
Reference
PMID:9227000
  Authors
MacDonald E, Kobilka BK, Scheinin M
  Title
Gene targeting--homing in on alpha 2-adrenoceptor-subtype function.
  Journal
Trends Pharmacol Sci 18:211-9 (1997)
DOI:10.1016/S0165-6147(97)01063-8
  Sequence
[hsa:151]

KEGG   ORTHOLOGY: K04140Help
Entry
K04140                      KO                                     

Name
ADRA2C
Definition
adrenergic receptor alpha-2C
Pathway
cGMP-PKG signaling pathway
Neuroactive ligand-receptor interaction
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04022 cGMP - PKG signaling pathway
    K04140  ADRA2C; adrenergic receptor alpha-2C
  Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K04140  ADRA2C; adrenergic receptor alpha-2C
G protein-coupled receptors [BR:ko04030]
 Class A. Rhodopsin family
  Biogenic amine
   Adrenaline [OT]
    K04140  ADRA2C; adrenergic receptor alpha-2C
BRITE hierarchy
Other DBs
Genes
HSA: 
152(ADRA2C)
PTR: 
465178(ADRA2C)
PPS: 
100993507(ADRA2C)
GGO: 
101153693(ADRA2C)
PON: 
100938399(ADRA2C)
NLE: 
100591173(ADRA2C)
MCC: 
719763(ADRA2C)
MCF: 
102129584(ADRA2C)
CSAB: 
103246439(ADRA2C)
RRO: 
RBB: 
SBQ: 
101052595(ADRA2C)
MMU: 
11553(Adra2c)
RNO: 
24175(Adra2c)
CGE: 
103161652(Adra2c)
NGI: 
103741158(Adra2c)
HGL: 
101723218(Adra2c)
CCAN: 
109687429(Adra2c)
TUP: 
102499472(ADRA2C)
CFA: 
488793(ADRA2C)
AML: 
100467814(ADRA2C)
FCA: 
101087990(ADRA2C)
PTG: 
AJU: 
106978827(ADRA2C)
BTA: 
407139(ADRA2C)
BOM: 
102285813(ADRA2C)
CHX: 
102181288(ADRA2C)
OAS: 
100170319(ADRA2C)
SSC: 
733706(ADRA2C)
CFR: 
102520676(ADRA2C)
CDK: 
105103347(ADRA2C)
BACU: 
103008893(ADRA2C)
LVE: 
103074700(ADRA2C)
EAI: 
MYB: 
102249134(ADRA2C)
MYD: 
102767191(ADRA2C)
RSS: 
109434491(ADRA2C)
PALE: 
102895430(ADRA2C)
LAV: 
100668918(ADRA2C)
MDO: 
100020740(ADRA2C)
SHR: 
100927538(ADRA2C)
OAA: 
GGA: 
428799(ADRA2C)
MGP: 
104909214(ADRA2C)
CJO: 
107314070(ADRA2C)
APLA: 
101790023(ADRA2C)
ACYG: 
106033335(ADRA2C)
TGU: 
101233463(ADRA2C)
GFR: 
102039660(ADRA2C)
FAB: 
101811765(ADRA2C)
PHI: 
102111432(ADRA2C)
PMAJ: 
107203559(ADRA2C)
CCW: 
104690916(ADRA2C)
FPG: 
101919690(ADRA2C)
FCH: 
102053781(ADRA2C)
CLV: 
102097195(ADRA2C)
AAM: 
106498672(ADRA2C)
ASN: 
102375154(ADRA2C)
AMJ: 
102568542(ADRA2C)
PSS: 
102447937(ADRA2C)
CMY: 
102937639(ADRA2C)
CPIC: 
PVT: 
GJA: 
107112872(ADRA2C)
XLA: 
108697938(adra2c.L) 108705869(adra2c.S)
XTR: 
100145449(adra2c)
NPR: 
108785823(ADRA2C)
DRE: 
266752(adra2c) 266754(adra2da) 266755(adra2db)
SRX: 
SANH: 
SGH: 
IPU: 
108260662(adra2c) 108262932(adra2c) 108278623
AMEX: 
TRU: 
TNG: 
LCO: 
NCC: 
MZE: 
OLA: 
XMA: 
CSEM: 
LCF: 
HCQ: 
BPEC: 
SASA: 
ELS: 
SFM: 
LCM: 
CMK: 
BFO: 
APLC: 
SKO: 
DPX: 
LAK: 
 » show all
TaxonomyKoalaUniProt
Reference
PMID:9227000
  Authors
MacDonald E, Kobilka BK, Scheinin M
  Title
Gene targeting--homing in on alpha 2-adrenoceptor-subtype function.
  Journal
Trends Pharmacol Sci 18:211-9 (1997)
DOI:10.1016/S0165-6147(97)01063-8
  Sequence
[hsa:152]

KEGG   ORTHOLOGY: K04141Help
Entry
K04141                      KO                                     

Name
ADRB1
Definition
adrenergic receptor beta-1
Pathway
Calcium signaling pathway
cGMP-PKG signaling pathway
cAMP signaling pathway
Neuroactive ligand-receptor interaction
Adrenergic signaling in cardiomyocytes
Gap junction
Regulation of lipolysis in adipocytes
Renin secretion
Salivary secretion
Dilated cardiomyopathy (DCM)
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04020 Calcium signaling pathway
    K04141  ADRB1; adrenergic receptor beta-1
   04024 cAMP signaling pathway
    K04141  ADRB1; adrenergic receptor beta-1
   04022 cGMP - PKG signaling pathway
    K04141  ADRB1; adrenergic receptor beta-1
  Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K04141  ADRB1; adrenergic receptor beta-1
 Cellular Processes
  Cellular community - eukaryotes
   04540 Gap junction
    K04141  ADRB1; adrenergic receptor beta-1
 Organismal Systems
  Endocrine system
   04923 Regulation of lipolysis in adipocyte
    K04141  ADRB1; adrenergic receptor beta-1
   04924 Renin secretion
    K04141  ADRB1; adrenergic receptor beta-1
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    K04141  ADRB1; adrenergic receptor beta-1
  Digestive system
   04970 Salivary secretion
    K04141  ADRB1; adrenergic receptor beta-1
 Human Diseases
  Cardiovascular diseases
   05414 Dilated cardiomyopathy (DCM)
    K04141  ADRB1; adrenergic receptor beta-1
G protein-coupled receptors [BR:ko04030]
 Class A. Rhodopsin family
  Biogenic amine
   Adrenaline [OT]
    K04141  ADRB1; adrenergic receptor beta-1
BRITE hierarchy
Other DBs
Genes
HSA: 
153(ADRB1)
PTR: 
466206(ADRB1)
PPS: 
100978740(ADRB1)
GGO: 
101149664(ADRB1)
PON: 
100441708(ADRB1)
NLE: 
100606030(ADRB1)
MCC: 
100426598(ADRB1)
MCF: 
107126443(ADRB1)
CSAB: 
103216543(ADRB1)
RRO: 
104659193(ADRB1)
RBB: 
108542470(ADRB1)
CJC: 
100387664(ADRB1)
MMU: 
11554(Adrb1)
RNO: 
24925(Adrb1)
CGE: 
NGI: 
103731758(Adrb1)
HGL: 
101706546(Adrb1)
CCAN: 
109678400(Adrb1)
OCU: 
100338084(ADRB1)
TUP: 
102478713(ADRB1)
CFA: 
493972(ADRB1)
AML: 
100471252(ADRB1)
FCA: 
493971(ADRB1)
BTA: 
281604(ADRB1)
BOM: 
102270402(ADRB1)
BIU: 
109553237(ADRB1)
PHD: 
102326477(ADRB1)
CHX: 
102187558(ADRB1)
OAS: 
443528(ADRB1)
SSC: 
397355(ADRB1)
CDK: 
105104750(ADRB1)
BACU: 
103003267(ADRB1)
LVE: 
103082012(ADRB1)
ECB: 
100146832(ADRB1)
MYB: 
102258046(ADRB1)
HAI: 
109392029(ADRB1)
RSS: 
109444084(ADRB1)
PALE: 
102880796(ADRB1)
LAV: 
100654973(ADRB1)
MDO: 
100027410(ADRB1)
OAA: 
100082919(ADRB1)
GGA: 
101750705(ADRB1) 430991(ADRB3)
MGP: 
100303680(ADRB1) 100379211(ADRB3)
CJO: 
107316142(ADRB1) 107323791(ADRB3)
APLA: 
101790405(ADRB1) 101801679(ADRB3)
ACYG: 
106031933(ADRB1) 106044379(ADRB3)
TGU: 
GFR: 
102034437(ADRB1)
FAB: 
101805929(ADRB1) 101808175(ADRB3)
PHI: 
102111297(ADRB3) 102113245(ADRB1)
PMAJ: 
107207049(ADRB1) 107213844(ADRB3)
FPG: 
101917348(ADRB1) 101918615(ADRB3)
FCH: 
102052904(ADRB1) 106631091(ADRB3)
CLV: 
102087468(ADRB1) 102099042(ADRB3)
AAM: 
ASN: 
102368318(ADRB1)
AMJ: 
102574660(ADRB1)
PSS: 
102447221(ADRB1)
CMY: 
102930847(ADRB1)
CPIC: 
101935916(ADRB1)
ACS: 
100553597(adrb3) 100563228(adrb1)
PVT: 
110071978(ADRB1) 110075175(ADRB3)
PBI: 
103066230(ADRB1)
GJA: 
107122433(ADRB1)
XLA: 
XTR: 
100487086(adrb1)
NPR: 
DRE: 
557194(adrb1) 558248(adrb3a) 792519(adrb3b)
SRX: 
SANH: 
SGH: 
IPU: 
AMEX: 
TRU: 
TNG: 
LCO: 
NCC: 
MZE: 
OLA: 
XMA: 
CSEM: 
LCF: 
HCQ: 
BPEC: 
SASA: 
ELS: 
SFM: 
LCM: 
102359969(ADRB1) 102361981(ADRB3)
CMK: 
103186583(adrb1) 103190260(adrb3)
PHU: 
CRG: 
LAK: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Pak Y, Pham N, Rotin D
  Title
Direct binding of the beta1 adrenergic receptor to the cyclic AMP-dependent guanine nucleotide exchange factor CNrasGEF leads to Ras activation.
  Journal
Mol Cell Biol 22:7942-52 (2002)
DOI:10.1128/MCB.22.22.7942-7952.2002
  Sequence
[hsa:153]

KEGG   ORTHOLOGY: K04142Help
Entry
K04142                      KO                                     

Name
ADRB2
Definition
adrenergic receptor beta-2
Pathway
Calcium signaling pathway
cGMP-PKG signaling pathway
cAMP signaling pathway
Neuroactive ligand-receptor interaction
Adrenergic signaling in cardiomyocytes
Regulation of lipolysis in adipocytes
Renin secretion
Salivary secretion
Disease
H00079  
Asthma
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04020 Calcium signaling pathway
    K04142  ADRB2; adrenergic receptor beta-2
   04024 cAMP signaling pathway
    K04142  ADRB2; adrenergic receptor beta-2
   04022 cGMP - PKG signaling pathway
    K04142  ADRB2; adrenergic receptor beta-2
  Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K04142  ADRB2; adrenergic receptor beta-2
 Organismal Systems
  Endocrine system
   04923 Regulation of lipolysis in adipocyte
    K04142  ADRB2; adrenergic receptor beta-2
   04924 Renin secretion
    K04142  ADRB2; adrenergic receptor beta-2
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    K04142  ADRB2; adrenergic receptor beta-2
  Digestive system
   04970 Salivary secretion
    K04142  ADRB2; adrenergic receptor beta-2
G protein-coupled receptors [BR:ko04030]
 Class A. Rhodopsin family
  Biogenic amine
   Adrenaline [OT]
    K04142  ADRB2; adrenergic receptor beta-2
BRITE hierarchy
Other DBs
Genes
HSA: 
154(ADRB2)
PTR: 
471690(ADRB2)
PPS: 
100983950(ADRB2)
GGO: 
101142746(ADRB2)
PON: 
100455509(ADRB2)
NLE: 
100589389(ADRB2)
MCC: 
710146(ADRB2)
MCF: 
102144318(ADRB2)
CSAB: 
103244769(ADRB2)
RRO: 
104680760(ADRB2)
RBB: 
108532068(ADRB2)
CJC: 
100414106(ADRB2)
SBQ: 
101034868(ADRB2)
MMU: 
11555(Adrb2)
RNO: 
24176(Adrb2)
CGE: 
100758902(Adrb2)
HGL: 
101708921(Adrb2)
CCAN: 
109699099(Adrb2)
OCU: 
100340821(ADRB2)
TUP: 
102479303(ADRB2)
CFA: 
403910(ADRB2)
AML: 
100474451(ADRB2)
UMR: 
103664828(ADRB2)
FCA: 
493767(ADRB2)
PTG: 
102963049(ADRB2)
AJU: 
106981678(ADRB2)
BTA: 
281605(ADRB2)
BOM: 
102287887(ADRB2)
BIU: 
109562177(ADRB2)
PHD: 
102324704(ADRB2)
CHX: 
102179381(ADRB2)
OAS: 
100170320(ADRB2)
SSC: 
397357(ADRB2)
CFR: 
102514031(ADRB2)
CDK: 
105097013(ADRB2)
BACU: 
103006153(ADRB2)
LVE: 
103071524(ADRB2)
ECB: 
100060659(ADRB2)
EPZ: 
103552981(ADRB2)
EAI: 
106838476(ADRB2)
MYB: 
102249639(ADRB2)
MYD: 
102758663(ADRB2)
HAI: 
109371751(ADRB2)
RSS: 
109448762(ADRB2)
PALE: 
102882861(ADRB2)
LAV: 
100664615(ADRB2)
MDO: 
100031542(ADRB2)
SHR: 
100928854(ADRB2)
GGA: 
427623(ADRB2)
MGP: 
100545804(ADRB2)
CJO: 
107320450(ADRB2)
APLA: 
101800857(ADRB2)
ACYG: 
106042769(ADRB2)
TGU: 
100221385(ADRB2)
GFR: 
102034502(ADRB2)
FAB: 
101808483(ADRB2)
PHI: 
102102944(ADRB2)
PMAJ: 
107210874(ADRB2)
CCW: 
104689646(ADRB2)
FPG: 
101919810(ADRB2)
FCH: 
102054857(ADRB2)
CLV: 
102087292(ADRB2)
AAM: 
106492678(ADRB3)
ASN: 
102376687(ADRB2)
AMJ: 
102567188(ADRB2)
PSS: 
102456356(ADRB2)
CMY: 
102947159(ADRB2)
CPIC: 
101934241(ADRB2)
ACS: 
100561097(adrb2)
PVT: 
PBI: 
103059387(ADRB2)
GJA: 
107106463(ADRB2)
XLA: 
398915(adrb2.S) 444218(adrb2.L)
XTR: 
100144654(adrb2)
NPR: 
DRE: 
100037315(adrb2b) 565838(adrb2a)
SRX: 
SANH: 
SGH: 
IPU: 
AMEX: 
TRU: 
TNG: 
LCO: 
NCC: 
MZE: 
OLA: 
XMA: 
CSEM: 
LCF: 
HCQ: 
BPEC: 
SASA: 
ELS: 
SFM: 
LCM: 
CMK: 
103188154(adrb2)
CIN: 
APLC: 
SKO: 
TUT: 
HRO: 
LGI: 
CRG: 
MYI: 
LAK: 
EPA: 
ADF: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Scarselli M, Donaldson JG
  Title
Constitutive internalization of G protein-coupled receptors and G proteins via clathrin-independent endocytosis.
  Journal
J Biol Chem 284:3577-85 (2009)
DOI:10.1074/jbc.M806819200
  Sequence
[hsa:154]

KEGG   ORTHOLOGY: K04143Help
Entry
K04143                      KO                                     

Name
ADRB3
Definition
adrenergic receptor beta-3
Pathway
Calcium signaling pathway
cGMP-PKG signaling pathway
Neuroactive ligand-receptor interaction
Regulation of lipolysis in adipocytes
Renin secretion
Salivary secretion
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04020 Calcium signaling pathway
    K04143  ADRB3; adrenergic receptor beta-3
   04022 cGMP - PKG signaling pathway
    K04143  ADRB3; adrenergic receptor beta-3
  Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K04143  ADRB3; adrenergic receptor beta-3
 Organismal Systems
  Endocrine system
   04923 Regulation of lipolysis in adipocyte
    K04143  ADRB3; adrenergic receptor beta-3
   04924 Renin secretion
    K04143  ADRB3; adrenergic receptor beta-3
  Digestive system
   04970 Salivary secretion
    K04143  ADRB3; adrenergic receptor beta-3
G protein-coupled receptors [BR:ko04030]
 Class A. Rhodopsin family
  Biogenic amine
   Adrenaline [OT]
    K04143  ADRB3; adrenergic receptor beta-3
BRITE hierarchy
Other DBs
Genes
HSA: 
155(ADRB3)
PTR: 
464113(ADRB3)
PPS: 
100972927(ADRB3)
GGO: 
101145102(ADRB3)
PON: 
100454445(ADRB3)
NLE: 
100596541(ADRB3)
MCC: 
699129(ADRB3)
MCF: 
102132220(ADRB3)
CSAB: 
103215635(ADRB3)
RRO: 
104679651(ADRB3)
RBB: 
108513564(ADRB3)
CJC: 
100396232(ADRB3)
SBQ: 
101029188(ADRB3)
MMU: 
11556(Adrb3)
RNO: 
25645(Adrb3)
CGE: 
100775030(Adrb3)
NGI: 
HGL: 
101721160(Adrb3)
CCAN: 
109675221(Adrb3)
OCU: 
100339100(ADRB3)
CFA: 
442979(ADRB3)
AML: 
100469495(ADRB3)
FCA: 
493930(ADRB3)
PTG: 
102962125(ADRB3)
BTA: 
281606(ADRB3)
BOM: 
102279772(ADRB3)
BIU: 
109553308(ADRB3)
PHD: 
102321437(ADRB3)
CHX: 
106503668(ADRB3)
OAS: 
100294559(ADRB3)
SSC: 
397356(ADRB3)
CFR: 
102520443(ADRB3)
CDK: 
105089947(ADRB3)
BACU: 
103018060(ADRB3)
LVE: 
103074465(ADRB3)
ECB: 
100147322(ADRB3)
EPZ: 
103567291(ADRB3)
EAI: 
106837694(ADRB3)
MYB: 
102249857(ADRB3)
MYD: 
102764740(ADRB3)
HAI: 
109393585(ADRB3)
RSS: 
109456091(ADRB3)
PALE: 
102879929(ADRB3)
LAV: 
100674524(ADRB3)
MDO: 
100032947(ADRB3)
SHR: 
100935351(ADRB3)
ASN: 
102373388(ADRB3)
AMJ: 
106737688(ADRB3)
CMY: 
BFO: 
APLC: 
SKO: 
ADF: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Belge C, Hammond J, Dubois-Deruy E, Manoury B, Hamelet J, Beauloye C, Markl A, Pouleur AC, Bertrand L, Esfahani H, Jnaoui K, Gotz KR, Nikolaev VO, Vanderper A, Herijgers P, Lobysheva I, Iaccarino G, Hilfiker-Kleiner D, Tavernier G, Langin D, Dessy C, Balligand JL
  Title
Enhanced expression of beta3-adrenoceptors in cardiac myocytes attenuates neurohormone-induced hypertrophic remodeling through nitric oxide synthase.
  Journal
Circulation 129:451-62 (2014)
DOI:10.1161/CIRCULATIONAHA.113.004940
  Sequence
[hsa:155]

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