KEGG   ORTHOLOGY: K04344Help
Entry
K04344                      KO                                     

Name
CACNA1A
Definition
voltage-dependent calcium channel P/Q type alpha-1A
Pathway
ko04010  MAPK signaling pathway
ko04020  Calcium signaling pathway
ko04721  Synaptic vesicle cycle
ko04723  Retrograde endocannabinoid signaling
ko04724  Glutamatergic synapse
ko04725  Cholinergic synapse
ko04726  Serotonergic synapse
ko04727  GABAergic synapse
ko04728  Dopaminergic synapse
ko04730  Long-term depression
ko04742  Taste transduction
ko04930  Type II diabetes mellitus
ko05032  Morphine addiction
ko05033  Nicotine addiction
Disease
H00063  Spinocerebellar ataxia (SCA)
H00606  Early infantile epileptic encephalopathy
H00749  Episodic ataxias
H00775  Familial or sporadic hemiplegic migraine
H01808  Hemiconvulsion-hemiplegia-epilepsy syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    K04344  CACNA1A; voltage-dependent calcium channel P/Q type alpha-1A
   04020 Calcium signaling pathway
    K04344  CACNA1A; voltage-dependent calcium channel P/Q type alpha-1A
 Organismal Systems
  Nervous system
   04724 Glutamatergic synapse
    K04344  CACNA1A; voltage-dependent calcium channel P/Q type alpha-1A
   04727 GABAergic synapse
    K04344  CACNA1A; voltage-dependent calcium channel P/Q type alpha-1A
   04725 Cholinergic synapse
    K04344  CACNA1A; voltage-dependent calcium channel P/Q type alpha-1A
   04728 Dopaminergic synapse
    K04344  CACNA1A; voltage-dependent calcium channel P/Q type alpha-1A
   04726 Serotonergic synapse
    K04344  CACNA1A; voltage-dependent calcium channel P/Q type alpha-1A
   04730 Long-term depression
    K04344  CACNA1A; voltage-dependent calcium channel P/Q type alpha-1A
   04723 Retrograde endocannabinoid signaling
    K04344  CACNA1A; voltage-dependent calcium channel P/Q type alpha-1A
   04721 Synaptic vesicle cycle
    K04344  CACNA1A; voltage-dependent calcium channel P/Q type alpha-1A
  Sensory system
   04742 Taste transduction
    K04344  CACNA1A; voltage-dependent calcium channel P/Q type alpha-1A
 Human Diseases
  Substance dependence
   05032 Morphine addiction
    K04344  CACNA1A; voltage-dependent calcium channel P/Q type alpha-1A
   05033 Nicotine addiction
    K04344  CACNA1A; voltage-dependent calcium channel P/Q type alpha-1A
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    K04344  CACNA1A; voltage-dependent calcium channel P/Q type alpha-1A
Ion channels [BR:ko04040]
 Voltage-gated cation channels
  Ca2+ channel, CACN alpha-1, CaVx.x
   K04344  CACNA1A; voltage-dependent calcium channel P/Q type alpha-1A
BRITE hierarchy
Other DBs
GO: 0005245
TC: 1.A.1.11.8 1.A.1.11.27
Genes
HSA: 773(CACNA1A)
PTR: 455766(CACNA1A)
PPS: 100971898(CACNA1A)
GGO: 101127257(CACNA1A)
PON: 100458387(CACNA1A)
NLE: 100602682(CACNA1A)
MCC: 718291(CACNA1A)
MCF: 102130052(CACNA1A)
CSAB: 103234371(CACNA1A)
RRO: 104661142(CACNA1A)
RBB: 108544091(CACNA1A)
CJC: 100390599(CACNA1A)
SBQ: 101046396(CACNA1A)
MMU: 12286(Cacna1a)
RNO: 25398(Cacna1a)
CGE: 100758171(Cacna1a)
NGI: 103751913(Cacna1a)
HGL: 101725815(Cacna1a)
CCAN: 109681262(Cacna1a)
OCU: 100009265(CACNA1A)
TUP: 102473903(CACNA1A)
CFA: 100686650(CACNA1A)
AML: 100473951(CACNA1A)
UMR: 103682191
ORO: 101378448(CACNA1A)
FCA: 101094827(CACNA1A)
PTG: 102962991(CACNA1A)
AJU: 106986103(CACNA1A)
BTA: 282648(CACNA1A)
BOM: 102266763(CACNA1A)
BIU: 109560900(CACNA1A)
PHD: 102336555(CACNA1A)
CHX: 102168441(CACNA1A)
OAS: 101120920(CACNA1A)
SSC: 100525387(CACNA1A)
CFR: 102516820(CACNA1A)
CDK: 105100784(CACNA1A)
BACU: 103007483(CACNA1A)
LVE: 103068318(CACNA1A)
OOR: 101275783(CACNA1A)
ECB: 100063873(CACNA1A)
EPZ: 103566268(CACNA1A)
EAI: 106844288(CACNA1A)
MYB: 102257882(CACNA1A)
MYD: 102771143(CACNA1A)
HAI: 109394251(CACNA1A)
RSS: 109454914(CACNA1A)
PALE: 102891789(CACNA1A)
LAV: 100655176(CACNA1A)
TMU: 101341628
MDO: 100021108(CACNA1A)
SHR: 100925240(CACNA1A)
OAA: 100078981(CACNA1A)
PHI: 102099919(CACNA1A)
FPG: 101919186(CACNA1A)
FCH: 102053332
AAM: 106499950
ASN: 102376033(CACNA1A)
AMJ: 102564806(CACNA1A)
PSS: 102447240
CMY: 102933709(CACNA1A)
CPIC: 101943820(CACNA1A)
ACS: 100557580(cacna1a)
PVT: 110082653(CACNA1A)
PBI: 103050605(CACNA1A)
GJA: 107116856(CACNA1A)
XLA: 108710372 373828(cacna1a.S)
XTR: 100492135(cacna1a)
NPR: 108794965(CACNA1A)
DRE: 569528(cacna1ab)
TRU: 101072720(cacna1a)
MZE: 101484868(cacna1a)
XMA: 102225112 102236322(cacna1a)
PRET: 103462507(cacna1a) 103468620
NFU: 107376625 107391184(cacna1a)
CSEM: 103383187(cacna1a) 103392961
LCF: 108880719 108880807(cacna1a)
BPEC: 110156590(cacna1a) 110172680
ELS: 105012190(cacna1a) 105024166
SFM: 108927499(cacna1a) 108930696
LCM: 102354855(CACNA1A)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Rose SJ, Kriener LH, Heinzer AK, Fan X, Raike RS, van den Maagdenberg AM, Hess EJ
  Title
The first knockin mouse model of episodic ataxia type 2.
  Journal
Exp Neurol 261:553-62 (2014)
DOI:10.1016/j.expneurol.2014.08.001
  Sequence
[hsa:773]

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