KEGG   ORTHOLOGY: K04344Help
Entry
K04344                      KO                                     

Name
CACNA1A
Definition
voltage-dependent calcium channel P/Q type alpha-1A
Pathway
MAPK signaling pathway
Calcium signaling pathway
Synaptic vesicle cycle
Retrograde endocannabinoid signaling
Glutamatergic synapse
Cholinergic synapse
Serotonergic synapse
GABAergic synapse
Dopaminergic synapse
Long-term depression
Taste transduction
Type II diabetes mellitus
Morphine addiction
Nicotine addiction
Disease
H00063  
Spinocerebellar ataxia (SCA)
H00606  
Early infantile epileptic encephalopathy
H00749  
Episodic ataxias
H00775  
Familial or sporadic hemiplegic migraine
H01808  
Hemiconvulsion-hemiplegia-epilepsy syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    K04344  CACNA1A; voltage-dependent calcium channel P/Q type alpha-1A
   04020 Calcium signaling pathway
    K04344  CACNA1A; voltage-dependent calcium channel P/Q type alpha-1A
 Organismal Systems
  Nervous system
   04724 Glutamatergic synapse
    K04344  CACNA1A; voltage-dependent calcium channel P/Q type alpha-1A
   04727 GABAergic synapse
    K04344  CACNA1A; voltage-dependent calcium channel P/Q type alpha-1A
   04725 Cholinergic synapse
    K04344  CACNA1A; voltage-dependent calcium channel P/Q type alpha-1A
   04728 Dopaminergic synapse
    K04344  CACNA1A; voltage-dependent calcium channel P/Q type alpha-1A
   04726 Serotonergic synapse
    K04344  CACNA1A; voltage-dependent calcium channel P/Q type alpha-1A
   04730 Long-term depression
    K04344  CACNA1A; voltage-dependent calcium channel P/Q type alpha-1A
   04723 Retrograde endocannabinoid signaling
    K04344  CACNA1A; voltage-dependent calcium channel P/Q type alpha-1A
   04721 Synaptic vesicle cycle
    K04344  CACNA1A; voltage-dependent calcium channel P/Q type alpha-1A
  Sensory system
   04742 Taste transduction
    K04344  CACNA1A; voltage-dependent calcium channel P/Q type alpha-1A
 Human Diseases
  Substance dependence
   05032 Morphine addiction
    K04344  CACNA1A; voltage-dependent calcium channel P/Q type alpha-1A
   05033 Nicotine addiction
    K04344  CACNA1A; voltage-dependent calcium channel P/Q type alpha-1A
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    K04344  CACNA1A; voltage-dependent calcium channel P/Q type alpha-1A
Ion channels [BR:ko04040]
 Voltage-gated cation channels
  Ca2+ channel, CACN alpha-1, CaVx.x
   K04344  CACNA1A; voltage-dependent calcium channel P/Q type alpha-1A
BRITE hierarchy
Other DBs
Genes
HSA: 
773(CACNA1A)
PTR: 
455766(CACNA1A)
PPS: 
100971898(CACNA1A)
GGO: 
101127257(CACNA1A)
PON: 
NLE: 
100602682(CACNA1A)
MCC: 
718291(CACNA1A)
MCF: 
102130052(CACNA1A)
CSAB: 
103234371(CACNA1A)
RRO: 
104661142(CACNA1A)
RBB: 
108544091(CACNA1A)
CJC: 
100390599(CACNA1A)
SBQ: 
101046396(CACNA1A)
MMU: 
12286(Cacna1a)
RNO: 
25398(Cacna1a)
CGE: 
100758171(Cacna1a)
NGI: 
103751913(Cacna1a)
HGL: 
101725815(Cacna1a)
CCAN: 
109681262(Cacna1a)
OCU: 
100009265(CACNA1A)
TUP: 
102473903(CACNA1A)
CFA: 
100686650(CACNA1A)
AML: 
100473951(CACNA1A)
UMR: 
FCA: 
101094827(CACNA1A)
PTG: 
102962991(CACNA1A)
AJU: 
106986103(CACNA1A)
BTA: 
282648(CACNA1A)
BOM: 
102266763(CACNA1A)
BIU: 
109560900(CACNA1A)
PHD: 
102336555(CACNA1A)
CHX: 
102168441(CACNA1A)
OAS: 
101120920(CACNA1A)
SSC: 
100525387(CACNA1A)
CFR: 
102516820(CACNA1A)
CDK: 
105100784(CACNA1A)
BACU: 
103007483(CACNA1A)
LVE: 
103068318(CACNA1A)
ECB: 
100063873(CACNA1A)
EPZ: 
103566268(CACNA1A)
EAI: 
106844288(CACNA1A)
MYB: 
102257882(CACNA1A)
MYD: 
102771143(CACNA1A)
HAI: 
109394251(CACNA1A)
RSS: 
109454914(CACNA1A)
PALE: 
102891789(CACNA1A)
LAV: 
100655176(CACNA1A)
MDO: 
100021108(CACNA1A)
SHR: 
100925240(CACNA1A)
OAA: 
100078981(CACNA1A)
PHI: 
102099919(CACNA1A)
FPG: 
101919186(CACNA1A)
FCH: 
AAM: 
ASN: 
102376033(CACNA1A)
AMJ: 
102564806(CACNA1A)
PSS: 
CMY: 
102933709(CACNA1A)
CPIC: 
101943820(CACNA1A)
ACS: 
100557580(cacna1a)
PVT: 
110082653(CACNA1A)
PBI: 
103050605(CACNA1A)
GJA: 
107116856(CACNA1A)
XLA: 
108710372 373828(cacna1a.S)
XTR: 
100492135(cacna1a)
NPR: 
108794965(CACNA1A)
DRE: 
569528(cacna1ab)
SRX: 
SANH: 
SGH: 
IPU: 
AMEX: 
TRU: 
101072720(cacna1a)
TNG: 
LCO: 
NCC: 
MZE: 
101484868(cacna1a)
OLA: 
XMA: 
CSEM: 
LCF: 
HCQ: 
BPEC: 
SASA: 
ELS: 
SFM: 
LCM: 
102354855(CACNA1A)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Rose SJ, Kriener LH, Heinzer AK, Fan X, Raike RS, van den Maagdenberg AM, Hess EJ
  Title
The first knockin mouse model of episodic ataxia type 2.
  Journal
Exp Neurol 261:553-62 (2014)
DOI:10.1016/j.expneurol.2014.08.001
  Sequence
[hsa:773]

KEGG   ORTHOLOGY: K04849Help
Entry
K04849                      KO                                     

Name
CACNA1B
Definition
voltage-dependent calcium channel N type alpha-1B
Pathway
MAPK signaling pathway
Calcium signaling pathway
Synaptic vesicle cycle
Retrograde endocannabinoid signaling
Cholinergic synapse
Serotonergic synapse
GABAergic synapse
Dopaminergic synapse
Type II diabetes mellitus
Morphine addiction
Nicotine addiction
Disease
H00831  
Primary dystonia
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    K04849  CACNA1B; voltage-dependent calcium channel N type alpha-1B
   04020 Calcium signaling pathway
    K04849  CACNA1B; voltage-dependent calcium channel N type alpha-1B
 Organismal Systems
  Nervous system
   04727 GABAergic synapse
    K04849  CACNA1B; voltage-dependent calcium channel N type alpha-1B
   04725 Cholinergic synapse
    K04849  CACNA1B; voltage-dependent calcium channel N type alpha-1B
   04728 Dopaminergic synapse
    K04849  CACNA1B; voltage-dependent calcium channel N type alpha-1B
   04726 Serotonergic synapse
    K04849  CACNA1B; voltage-dependent calcium channel N type alpha-1B
   04723 Retrograde endocannabinoid signaling
    K04849  CACNA1B; voltage-dependent calcium channel N type alpha-1B
   04721 Synaptic vesicle cycle
    K04849  CACNA1B; voltage-dependent calcium channel N type alpha-1B
 Human Diseases
  Substance dependence
   05032 Morphine addiction
    K04849  CACNA1B; voltage-dependent calcium channel N type alpha-1B
   05033 Nicotine addiction
    K04849  CACNA1B; voltage-dependent calcium channel N type alpha-1B
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    K04849  CACNA1B; voltage-dependent calcium channel N type alpha-1B
Ion channels [BR:ko04040]
 Voltage-gated cation channels
  Ca2+ channel, CACN alpha-1, CaVx.x
   K04849  CACNA1B; voltage-dependent calcium channel N type alpha-1B
BRITE hierarchy
Other DBs
Genes
HSA: 
774(CACNA1B)
PTR: 
464893(CACNA1B)
PPS: 
100979369(CACNA1B)
GGO: 
101123776(CACNA1B)
PON: 
100450868(CACNA1B)
NLE: 
100584807(CACNA1B)
MCC: 
721452(CACNA1B)
MCF: 
CSAB: 
103239541(CACNA1B)
RRO: 
104669605(CACNA1B)
RBB: 
108542921(CACNA1B)
CJC: 
100390442(CACNA1B)
SBQ: 
101049976(CACNA1B)
MMU: 
12287(Cacna1b)
RNO: 
257648(Cacna1b)
NGI: 
103732608(Cacna1b)
HGL: 
101697609(Cacna1b)
CCAN: 
OCU: 
100008979(CACNA1B)
TUP: 
102498317(CACNA1B)
CFA: 
480660(CACNA1B)
AML: 
100466608(CACNA1B)
UMR: 
103675324(CACNA1B)
FCA: 
101087362(CACNA1B)
PTG: 
102954775(CACNA1B)
AJU: 
BTA: 
282410(CACNA1B)
BOM: 
102266839(CACNA1B)
BIU: 
109565692(CACNA1B)
PHD: 
102330644(CACNA1B)
CHX: 
102189138(CACNA1B)
OAS: 
SSC: 
102164336(CACNA1B)
CFR: 
102521766(CACNA1B)
CDK: 
105102103(CACNA1B)
BACU: 
103004988(CACNA1B)
LVE: 
103073411(CACNA1B)
ECB: 
100058760(CACNA1B)
EPZ: 
103554173(CACNA1B)
EAI: 
106822757(CACNA1B)
MYB: 
102245786(CACNA1B)
MYD: 
102756826(CACNA1B)
HAI: 
109382541(CACNA1B)
RSS: 
109437268(CACNA1B)
PALE: 
102877847(CACNA1B)
LAV: 
100660444(CACNA1B)
MDO: 
100023896(CACNA1B)
SHR: 
100933192(CACNA1B)
OAA: 
100681261(CACNA1B)
GGA: 
374169(CACNA1B)
MGP: 
100539318(CACNA1B)
CJO: 
107321666(CACNA1B)
APLA: 
101794161(CACNA1B)
ACYG: 
106037093(CACNA1B)
TGU: 
100230125(CACNA1B)
GFR: 
102043304(CACNA1B)
FAB: 
101812454(CACNA1B)
PHI: 
102107124(CACNA1B)
PMAJ: 
107211935(CACNA1B)
CCW: 
104688232(CACNA1B)
FPG: 
101922058(CACNA1B)
FCH: 
102058219(CACNA1B)
CLV: 
102086328(CACNA1B)
AAM: 
106497478(CACNA1B)
ASN: 
102374664(CACNA1B)
AMJ: 
102564626(CACNA1B)
PSS: 
102452356(CACNA1B)
CMY: 
102935334(CACNA1B)
CPIC: 
101941901(CACNA1B)
ACS: 
100565533(cacna1b)
PVT: 
110089800(CACNA1B)
PBI: 
GJA: 
107118784(CACNA1B)
XLA: 
100462926(cacna1b.S) 108699890
XTR: 
NPR: 
108794388(CACNA1B)
DRE: 
555941(cacna1ba) 562796(cacna1bb)
SRX: 
SANH: 
SGH: 
IPU: 
AMEX: 
TRU: 
101072690(cacna1b)
TNG: 
LCO: 
NCC: 
MZE: 
OLA: 
XMA: 
CSEM: 
LCF: 
HCQ: 
BPEC: 
SASA: 
ELS: 
SFM: 
LCM: 
102345610(CACNA1B)
CMK: 
103180424(cacna1b)
CIN: 
LGI: 
OBI: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Keum D, Baek C, Kim DI, Kweon HJ, Suh BC
  Title
Voltage-dependent regulation of CaV2.2 channels by Gq-coupled receptor is facilitated by membrane-localized beta subunit.
  Journal
J Gen Physiol 144:297-309 (2014)
DOI:10.1085/jgp.201411245
  Sequence
[hsa:774]

KEGG   ORTHOLOGY: K04850Help
Entry
K04850                      KO                                     

Name
CACNA1C
Definition
voltage-dependent calcium channel L type alpha-1C
Pathway
MAPK signaling pathway
Calcium signaling pathway
cGMP-PKG signaling pathway
cAMP signaling pathway
Cardiac muscle contraction
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Circadian entrainment
Long-term potentiation
Retrograde endocannabinoid signaling
Glutamatergic synapse
Cholinergic synapse
Serotonergic synapse
GABAergic synapse
Dopaminergic synapse
Taste transduction
Insulin secretion
GnRH signaling pathway
Oxytocin signaling pathway
Renin secretion
Aldosterone synthesis and secretion
Type II diabetes mellitus
Alzheimer's disease
Amphetamine addiction
Hypertrophic cardiomyopathy (HCM)
Arrhythmogenic right ventricular cardiomyopathy (ARVC)
Dilated cardiomyopathy (DCM)
Disease
H00720  
Long QT syndrome
H00728  
Brugada syndrome (BRS)
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    K04850  CACNA1C; voltage-dependent calcium channel L type alpha-1C
   04020 Calcium signaling pathway
    K04850  CACNA1C; voltage-dependent calcium channel L type alpha-1C
   04024 cAMP signaling pathway
    K04850  CACNA1C; voltage-dependent calcium channel L type alpha-1C
   04022 cGMP - PKG signaling pathway
    K04850  CACNA1C; voltage-dependent calcium channel L type alpha-1C
 Organismal Systems
  Endocrine system
   04911 Insulin secretion
    K04850  CACNA1C; voltage-dependent calcium channel L type alpha-1C
   04912 GnRH signaling pathway
    K04850  CACNA1C; voltage-dependent calcium channel L type alpha-1C
   04921 Oxytocin signaling pathway
    K04850  CACNA1C; voltage-dependent calcium channel L type alpha-1C
   04924 Renin secretion
    K04850  CACNA1C; voltage-dependent calcium channel L type alpha-1C
   04925 Aldosterone synthesis and secretion
    K04850  CACNA1C; voltage-dependent calcium channel L type alpha-1C
  Circulatory system
   04260 Cardiac muscle contraction
    K04850  CACNA1C; voltage-dependent calcium channel L type alpha-1C
   04261 Adrenergic signaling in cardiomyocytes
    K04850  CACNA1C; voltage-dependent calcium channel L type alpha-1C
   04270 Vascular smooth muscle contraction
    K04850  CACNA1C; voltage-dependent calcium channel L type alpha-1C
  Nervous system
   04724 Glutamatergic synapse
    K04850  CACNA1C; voltage-dependent calcium channel L type alpha-1C
   04727 GABAergic synapse
    K04850  CACNA1C; voltage-dependent calcium channel L type alpha-1C
   04725 Cholinergic synapse
    K04850  CACNA1C; voltage-dependent calcium channel L type alpha-1C
   04728 Dopaminergic synapse
    K04850  CACNA1C; voltage-dependent calcium channel L type alpha-1C
   04726 Serotonergic synapse
    K04850  CACNA1C; voltage-dependent calcium channel L type alpha-1C
   04720 Long-term potentiation
    K04850  CACNA1C; voltage-dependent calcium channel L type alpha-1C
   04723 Retrograde endocannabinoid signaling
    K04850  CACNA1C; voltage-dependent calcium channel L type alpha-1C
  Sensory system
   04742 Taste transduction
    K04850  CACNA1C; voltage-dependent calcium channel L type alpha-1C
  Environmental adaptation
   04713 Circadian entrainment
    K04850  CACNA1C; voltage-dependent calcium channel L type alpha-1C
 Human Diseases
  Neurodegenerative diseases
   05010 Alzheimer's disease
    K04850  CACNA1C; voltage-dependent calcium channel L type alpha-1C
  Substance dependence
   05031 Amphetamine addiction
    K04850  CACNA1C; voltage-dependent calcium channel L type alpha-1C
  Cardiovascular diseases
   05410 Hypertrophic cardiomyopathy (HCM)
    K04850  CACNA1C; voltage-dependent calcium channel L type alpha-1C
   05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC)
    K04850  CACNA1C; voltage-dependent calcium channel L type alpha-1C
   05414 Dilated cardiomyopathy (DCM)
    K04850  CACNA1C; voltage-dependent calcium channel L type alpha-1C
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    K04850  CACNA1C; voltage-dependent calcium channel L type alpha-1C
Ion channels [BR:ko04040]
 Voltage-gated cation channels
  Ca2+ channel, CACN alpha-1, CaVx.x
   K04850  CACNA1C; voltage-dependent calcium channel L type alpha-1C
BRITE hierarchy
Other DBs
Genes
HSA: 
775(CACNA1C)
PTR: 
466915(CACNA1C)
PPS: 
100971701(CACNA1C)
GGO: 
101134060(CACNA1C)
PON: 
100442085(CACNA1C)
NLE: 
100580437(CACNA1C)
MCC: 
721721(CACNA1C)
MCF: 
CSAB: 
103218385(CACNA1C)
RRO: 
RBB: 
108522695(CACNA1C)
CJC: 
100406735(CACNA1C)
SBQ: 
101040048(CACNA1C)
MMU: 
12288(Cacna1c)
RNO: 
24239(Cacna1c)
CGE: 
100754788(Cacna1c)
NGI: 
103739378(Cacna1c)
HGL: 
101717129(Cacna1c)
CCAN: 
OCU: 
100101555(CACNA1C)
TUP: 
CFA: 
403516(CACNA1C)
AML: 
100479715(CACNA1C)
UMR: 
103675706(CACNA1C)
FCA: 
101082923(CACNA1C)
PTG: 
102956322(CACNA1C)
AJU: 
106965473(CACNA1C)
BTA: 
408015(CACNA1C)
BOM: 
102277590(CACNA1C)
BIU: 
109558615(CACNA1C)
PHD: 
102319156(CACNA1C)
CHX: 
100861292(CACNA1C)
OAS: 
101116562(CACNA1C)
SSC: 
100518733(CACNA1C)
CFR: 
102524149(CACNA1C)
CDK: 
BACU: 
103019389(CACNA1C)
LVE: 
103087340(CACNA1C)
ECB: 
100049924(CACNA1C)
EPZ: 
EAI: 
106839455(CACNA1C)
MYB: 
102240225(CACNA1C)
MYD: 
102753812(CACNA1C)
HAI: 
109388950(CACNA1C)
RSS: 
109461209(CACNA1C)
PALE: 
102882682(CACNA1C)
LAV: 
100663323(CACNA1C)
MDO: 
100021421(CACNA1C)
SHR: 
100926503(CACNA1C)
GGA: 
395891(CACNA1C)
MGP: 
100547459(CACNA1C)
CJO: 
107315213(CACNA1C)
APLA: 
101790062(CACNA1C)
ACYG: 
106030933(CACNA1C)
TGU: 
100218244(CACNA1C)
GFR: 
FAB: 
101815051(CACNA1C)
PHI: 
102106069(CACNA1C)
PMAJ: 
107204397(CACNA1C)
CCW: 
104692245(CACNA1C)
FPG: 
101916694(CACNA1C)
FCH: 
102048150(CACNA1C)
CLV: 
102095010(CACNA1C)
AAM: 
106488364(CACNA1C)
ASN: 
102377475(CACNA1C)
AMJ: 
102575519(CACNA1C)
PSS: 
102451554(CACNA1C)
CMY: 
102940198(CACNA1C)
CPIC: 
101946823(CACNA1C)
ACS: 
100553244(cacna1c)
PVT: 
110076659(CACNA1C)
PBI: 
103062045(CACNA1C)
GJA: 
107120231(CACNA1C)
XLA: 
100462911(cacna1c.S) 108704565
XTR: 
100488055(cacna1c)
NPR: 
DRE: 
170581(cacna1c)
SRX: 
SANH: 
SGH: 
IPU: 
AMEX: 
TRU: 
TNG: 
LCO: 
104940547(cacna1c)
NCC: 
MZE: 
101471946(cacna1c)
OLA: 
XMA: 
CSEM: 
103382787(cacna1c)
LCF: 
HCQ: 
BPEC: 
SASA: 
ELS: 
SFM: 
108920904(cacna1c)
LCM: 
102357941(CACNA1C)
CMK: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Tiwari S, Zhang Y, Heller J, Abernethy DR, Soldatov NM
  Title
Atherosclerosis-related molecular alteration of the human CaV1.2 calcium channel alpha1C subunit.
  Journal
Proc Natl Acad Sci U S A 103:17024-9 (2006)
DOI:10.1073/pnas.0606539103
  Sequence
[hsa:775]

KEGG   ORTHOLOGY: K04851Help
Entry
K04851                      KO                                     

Name
CACNA1D
Definition
voltage-dependent calcium channel L type alpha-1D
Pathway
MAPK signaling pathway
Calcium signaling pathway
cGMP-PKG signaling pathway
cAMP signaling pathway
Cellular senescence
Cardiac muscle contraction
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Tight junction
Circadian entrainment
Retrograde endocannabinoid signaling
Glutamatergic synapse
Cholinergic synapse
Serotonergic synapse
GABAergic synapse
Dopaminergic synapse
Insulin secretion
GnRH signaling pathway
Oxytocin signaling pathway
Renin secretion
Aldosterone synthesis and secretion
Type II diabetes mellitus
Carbohydrate digestion and absorption
Alzheimer's disease
Amphetamine addiction
Hypertrophic cardiomyopathy (HCM)
Arrhythmogenic right ventricular cardiomyopathy (ARVC)
Dilated cardiomyopathy (DCM)
Disease
H01603  
Primary aldosteronism
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    K04851  CACNA1D; voltage-dependent calcium channel L type alpha-1D
   04020 Calcium signaling pathway
    K04851  CACNA1D; voltage-dependent calcium channel L type alpha-1D
   04024 cAMP signaling pathway
    K04851  CACNA1D; voltage-dependent calcium channel L type alpha-1D
   04022 cGMP - PKG signaling pathway
    K04851  CACNA1D; voltage-dependent calcium channel L type alpha-1D
 Cellular Processes
  Cell growth and death
   04218 Cellular senescence
    K04851  CACNA1D; voltage-dependent calcium channel L type alpha-1D
  Cellular community - eukaryotes
   04530 Tight junction
    K04851  CACNA1D; voltage-dependent calcium channel L type alpha-1D
 Organismal Systems
  Endocrine system
   04911 Insulin secretion
    K04851  CACNA1D; voltage-dependent calcium channel L type alpha-1D
   04912 GnRH signaling pathway
    K04851  CACNA1D; voltage-dependent calcium channel L type alpha-1D
   04921 Oxytocin signaling pathway
    K04851  CACNA1D; voltage-dependent calcium channel L type alpha-1D
   04924 Renin secretion
    K04851  CACNA1D; voltage-dependent calcium channel L type alpha-1D
   04925 Aldosterone synthesis and secretion
    K04851  CACNA1D; voltage-dependent calcium channel L type alpha-1D
  Circulatory system
   04260 Cardiac muscle contraction
    K04851  CACNA1D; voltage-dependent calcium channel L type alpha-1D
   04261 Adrenergic signaling in cardiomyocytes
    K04851  CACNA1D; voltage-dependent calcium channel L type alpha-1D
   04270 Vascular smooth muscle contraction
    K04851  CACNA1D; voltage-dependent calcium channel L type alpha-1D
  Digestive system
   04973 Carbohydrate digestion and absorption
    K04851  CACNA1D; voltage-dependent calcium channel L type alpha-1D
  Nervous system
   04724 Glutamatergic synapse
    K04851  CACNA1D; voltage-dependent calcium channel L type alpha-1D
   04727 GABAergic synapse
    K04851  CACNA1D; voltage-dependent calcium channel L type alpha-1D
   04725 Cholinergic synapse
    K04851  CACNA1D; voltage-dependent calcium channel L type alpha-1D
   04728 Dopaminergic synapse
    K04851  CACNA1D; voltage-dependent calcium channel L type alpha-1D
   04726 Serotonergic synapse
    K04851  CACNA1D; voltage-dependent calcium channel L type alpha-1D
   04723 Retrograde endocannabinoid signaling
    K04851  CACNA1D; voltage-dependent calcium channel L type alpha-1D
  Environmental adaptation
   04713 Circadian entrainment
    K04851  CACNA1D; voltage-dependent calcium channel L type alpha-1D
 Human Diseases
  Neurodegenerative diseases
   05010 Alzheimer's disease
    K04851  CACNA1D; voltage-dependent calcium channel L type alpha-1D
  Substance dependence
   05031 Amphetamine addiction
    K04851  CACNA1D; voltage-dependent calcium channel L type alpha-1D
  Cardiovascular diseases
   05410 Hypertrophic cardiomyopathy (HCM)
    K04851  CACNA1D; voltage-dependent calcium channel L type alpha-1D
   05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC)
    K04851  CACNA1D; voltage-dependent calcium channel L type alpha-1D
   05414 Dilated cardiomyopathy (DCM)
    K04851  CACNA1D; voltage-dependent calcium channel L type alpha-1D
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    K04851  CACNA1D; voltage-dependent calcium channel L type alpha-1D
Ion channels [BR:ko04040]
 Voltage-gated cation channels
  Ca2+ channel, CACN alpha-1, CaVx.x
   K04851  CACNA1D; voltage-dependent calcium channel L type alpha-1D
BRITE hierarchy
Other DBs
Genes
HSA: 
776(CACNA1D)
PTR: 
460447(CACNA1D)
PPS: 
100975108(CACNA1D)
GGO: 
101140987(CACNA1D)
PON: 
100453904(CACNA1D)
NLE: 
100600997(CACNA1D)
MCC: 
693924(CACNA1D)
MCF: 
102138213(CACNA1D)
CSAB: 
103227762(CACNA1D)
RRO: 
104672388(CACNA1D)
RBB: 
108515198(CACNA1D)
CJC: 
100397940(CACNA1D)
SBQ: 
101043152(CACNA1D)
MMU: 
12289(Cacna1d)
RNO: 
29716(Cacna1d)
CGE: 
100772497(Cacna1d)
NGI: 
103749025(Cacna1d)
HGL: 
101714832(Cacna1d)
CCAN: 
109674812(Cacna1d)
OCU: 
100327259(CACNA1D)
TUP: 
102484770(CACNA1D)
CFA: 
484724(CACNA1D)
AML: 
100467700(CACNA1D)
UMR: 
103674739(CACNA1D)
FCA: 
101088394(CACNA1D)
PTG: 
102958456(CACNA1D)
AJU: 
106986998(CACNA1D)
BTA: 
408013(CACNA1D)
BOM: 
102271623(CACNA1D)
BIU: 
109576190(CACNA1D)
PHD: 
102335896(CACNA1D)
CHX: 
102174706(CACNA1D)
OAS: 
101106371(CACNA1D)
SSC: 
100511102(CACNA1D)
CFR: 
CDK: 
BACU: 
103001906(CACNA1D)
LVE: 
103074544(CACNA1D)
ECB: 
100051186(CACNA1D)
EPZ: 
EAI: 
106822066(CACNA1D)
MYB: 
102259218(CACNA1D)
MYD: 
102761441(CACNA1D)
HAI: 
109395944(CACNA1D)
RSS: 
109443619(CACNA1D)
PALE: 
102888351(CACNA1D)
LAV: 
100659992(CACNA1D)
MDO: 
100014450(CACNA1D)
SHR: 
100919750(CACNA1D)
OAA: 
100077296(CACNA1D)
GGA: 
395895(CACNA1D)
MGP: 
100545748(CACNA1D)
CJO: 
107319871(CACNA1D)
APLA: 
101803307(CACNA1D)
ACYG: 
106048937(CACNA1D)
TGU: 
100226925(CACNA1D)
GFR: 
102035179(CACNA1D)
FAB: 
101819434(CACNA1D)
PHI: 
102103301(CACNA1D)
PMAJ: 
107210294(CACNA1D)
CCW: 
104683258(CACNA1D)
FPG: 
101912795(CACNA1D)
FCH: 
102054190(CACNA1D)
CLV: 
102091108(CACNA1D)
AAM: 
106488627(CACNA1D)
ASN: 
102373960(CACNA1D)
AMJ: 
102576817(CACNA1D)
PSS: 
102447276(CACNA1D)
CMY: 
102934282(CACNA1D)
CPIC: 
101951786(CACNA1D)
ACS: 
100554865(cacna1d)
PVT: 
110084495(CACNA1D)
PBI: 
103056075(CACNA1D)
GJA: 
107116832(CACNA1D)
XLA: 
100462912(cacna1d.L) 108704388
NPR: 
108786047(CACNA1D)
DRE: 
403310(cacna1da)
SRX: 
SANH: 
SGH: 
IPU: 
AMEX: 
TRU: 
TNG: 
LCO: 
NCC: 
MZE: 
OLA: 
XMA: 
102234425(cacna1d)
CSEM: 
LCF: 
HCQ: 
BPEC: 
SASA: 
ELS: 
SFM: 
LCM: 
102360815(CACNA1D)
CMK: 
103185068(cacna1d)
BFO: 
CIN: 
SPU: 
APLC: 
SKO: 
DME: 
Dmel_CG4894(Ca-alpha1D)
DER: 
DPE: 
DSE: 
DSI: 
Dsimw501_GD24041(Dsim_GD24041)
DWI: 
DYA: 
DGR: 
DVI: 
MDE: 
AGA: 
AAG: 
AME: 
100578899(Cav1a)
BIM: 
BTER: 
SOC: 
AEC: 
ACEP: 
PBAR: 
HST: 
CFO: 
LHU: 
PGC: 
NVI: 
TCA: 
DPA: 
NVL: 
BMOR: 
DPL: 
PXY: 
API: 
DNX: 
PHU: 
FCD: 
DPX: 
ISC: 
TUT: 
CEL: 
CELE_C48A7.1(egl-19)
CBR: 
CBG05858(Cbr-egl-19)
NAI: 
BMY: 
LOA: 
TSP: 
HRO: 
LGI: 
CRG: 
OBI: 
LAK: 
SMM: 
SHX: 
OVI: 
ADF: 
CRE: 
MPP: 
SRE: 
PTM: 
SMIN: 
v1.2.021642.t1(symbB.v1.2.021642.t1)
AAF: 
PIF: 
PSOJ: 
SPAR: 
GTT: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Baig SM, Koschak A, Lieb A, Gebhart M, Dafinger C, Nurnberg G, Ali A, Ahmad I, Sinnegger-Brauns MJ, Brandt N, Engel J, Mangoni ME, Farooq M, Khan HU, Nurnberg P, Striessnig J, Bolz HJ
  Title
Loss of Ca(v)1.3 (CACNA1D) function in a human channelopathy with bradycardia and congenital deafness.
  Journal
Nat Neurosci 14:77-84 (2011)
DOI:10.1038/nn.2694
Reference
PMID:1309948
  Authors
Seino S, Chen L, Seino M, Blondel O, Takeda J, Johnson JH, Bell GI
  Title
Cloning of the alpha 1 subunit of a voltage-dependent calcium channel expressed in pancreatic beta cells.
  Journal
Proc Natl Acad Sci U S A 89:584-8 (1992)
DOI:10.1073/pnas.89.2.584
  Sequence
[hsa:776]

KEGG   ORTHOLOGY: K04852Help
Entry
K04852                      KO                                     

Name
CACNA1E
Definition
voltage-dependent calcium channel R type alpha-1E
Pathway
MAPK signaling pathway
Calcium signaling pathway
Type II diabetes mellitus
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    K04852  CACNA1E; voltage-dependent calcium channel R type alpha-1E
   04020 Calcium signaling pathway
    K04852  CACNA1E; voltage-dependent calcium channel R type alpha-1E
 Human Diseases
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    K04852  CACNA1E; voltage-dependent calcium channel R type alpha-1E
Ion channels [BR:ko04040]
 Voltage-gated cation channels
  Ca2+ channel, CACN alpha-1, CaVx.x
   K04852  CACNA1E; voltage-dependent calcium channel R type alpha-1E
BRITE hierarchy
Other DBs
Genes
HSA: 
777(CACNA1E)
PTR: 
457564(CACNA1E)
PPS: 
100973580(CACNA1E)
GGO: 
101152448(CACNA1E)
PON: 
NLE: 
100607010(CACNA1E)
MCC: 
718092(CACNA1E)
MCF: 
102137898(CACNA1E)
CSAB: 
103230478(CACNA1E)
RRO: 
104666781(CACNA1E)
RBB: 
CJC: 
100406548(CACNA1E)
SBQ: 
101040860(CACNA1E)
MMU: 
12290(Cacna1e)
RNO: 
54234(Cacna1e)
CGE: 
100773594(Cacna1e)
NGI: 
103731375(Cacna1e)
HGL: 
101701145(Cacna1e)
CCAN: 
109680409(Cacna1e)
OCU: 
100009403(CACNA1E)
TUP: 
102488737(CACNA1E)
CFA: 
490305(CACNA1E)
AML: 
100466242(CACNA1E)
UMR: 
103672437(CACNA1E)
FCA: 
101093985(CACNA1E)
PTG: 
AJU: 
106966786(CACNA1E)
BTA: 
353113(CACNA1E)
BOM: 
102271361(CACNA1E)
BIU: 
109570739(CACNA1E)
PHD: 
102323438(CACNA1E)
CHX: 
102184834(CACNA1E)
OAS: 
101102503(CACNA1E)
SSC: 
100511769(CACNA1E)
CFR: 
102509504(CACNA1E)
CDK: 
105096253(CACNA1E)
BACU: 
103008378(CACNA1E)
LVE: 
103070069(CACNA1E)
ECB: 
100054582(CACNA1E)
EPZ: 
103552092(CACNA1E)
EAI: 
106833978(CACNA1E)
MYB: 
102258772(CACNA1E)
MYD: 
102766294(CACNA1E)
HAI: 
109371489(CACNA1E)
RSS: 
109448740(CACNA1E)
PALE: 
102894818(CACNA1E)
LAV: 
100663606(CACNA1E)
MDO: 
100017762(CACNA1E)
SHR: 
100915867(CACNA1E)
OAA: 
100081909(CACNA1E)
GGA: 
424412(CACNA1E)
MGP: 
100547277(CACNA1E)
CJO: 
107317272(CACNA1E)
APLA: 
101795250(CACNA1E)
ACYG: 
106047781(CACNA1E)
TGU: 
100221799(CACNA1E)
GFR: 
102043868(CACNA1E)
FAB: 
101806626(CACNA1E)
PHI: 
102110220(CACNA1E)
PMAJ: 
107208269(CACNA1E)
CCW: 
FPG: 
101921612(CACNA1E)
FCH: 
102050734(CACNA1E)
CLV: 
102097507(CACNA1E)
AAM: 
ASN: 
102369133(CACNA1E)
AMJ: 
102561875(CACNA1E)
PSS: 
102444760(CACNA1E)
CMY: 
102946100(CACNA1E)
CPIC: 
101940446(CACNA1E)
ACS: 
100567913(cacna1e)
PVT: 
110077061(CACNA1E)
PBI: 
103051634(CACNA1E)
GJA: 
XLA: 
100462927(cacna1e.L) 108715639
XTR: 
100488514(cacna1e)
NPR: 
108792573(CACNA1E)
DRE: 
564274(cacna1e)
SRX: 
SANH: 
SGH: 
IPU: 
AMEX: 
TRU: 
TNG: 
LCO: 
NCC: 
MZE: 
101487658(cacna1e)
OLA: 
XMA: 
CSEM: 
LCF: 
HCQ: 
BPEC: 
SASA: 
ELS: 
SFM: 
LCM: 
102362201(CACNA1E)
CMK: 
103184804(cacna1e)
CRE: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Kamp MA, Krieger A, Henry M, Hescheler J, Weiergraber M, Schneider T
  Title
Presynaptic 'Ca2.3-containing' E-type Ca channels share dual roles during neurotransmitter release.
  Journal
Eur J Neurosci 21:1617-25 (2005)
DOI:10.1111/j.1460-9568.2005.03984.x
  Sequence
[hsa:777]

KEGG   ORTHOLOGY: K04854Help
Entry
K04854                      KO                                     

Name
CACNA1G
Definition
voltage-dependent calcium channel T type alpha-1G
Pathway
MAPK signaling pathway
Calcium signaling pathway
Circadian entrainment
Aldosterone synthesis and secretion
Type II diabetes mellitus
Disease
H00063  
Spinocerebellar ataxia (SCA)
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    K04854  CACNA1G; voltage-dependent calcium channel T type alpha-1G
   04020 Calcium signaling pathway
    K04854  CACNA1G; voltage-dependent calcium channel T type alpha-1G
 Organismal Systems
  Endocrine system
   04925 Aldosterone synthesis and secretion
    K04854  CACNA1G; voltage-dependent calcium channel T type alpha-1G
  Environmental adaptation
   04713 Circadian entrainment
    K04854  CACNA1G; voltage-dependent calcium channel T type alpha-1G
 Human Diseases
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    K04854  CACNA1G; voltage-dependent calcium channel T type alpha-1G
Ion channels [BR:ko04040]
 Voltage-gated cation channels
  Ca2+ channel, CACN alpha-1, CaVx.x
   K04854  CACNA1G; voltage-dependent calcium channel T type alpha-1G
BRITE hierarchy
Other DBs
Genes
HSA: 
8913(CACNA1G)
PTR: 
455128(CACNA1G)
PPS: 
100983419(CACNA1G)
GGO: 
101136486(CACNA1G)
PON: 
100457657(CACNA1G)
NLE: 
100588419(CACNA1G)
MCC: 
706230(CACNA1G)
MCF: 
101925139(CACNA1G)
CSAB: 
103242929(CACNA1G)
RRO: 
104680284(CACNA1G)
RBB: 
108516476(CACNA1G)
CJC: 
100415104(CACNA1G)
SBQ: 
101028952(CACNA1G)
MMU: 
12291(Cacna1g)
RNO: 
29717(Cacna1g)
CGE: 
100761932(Cacna1g)
NGI: 
103738394(Cacna1g)
HGL: 
101709921(Cacna1g)
CCAN: 
109681484(Cacna1g)
OCU: 
100346309(CACNA1G)
TUP: 
102486198(CACNA1G)
CFA: 
491083(CACNA1G)
AML: 
100464603(CACNA1G)
UMR: 
103660890(CACNA1G)
FCA: 
101098757(CACNA1G)
PTG: 
102969277(CACNA1G)
AJU: 
106985176(CACNA1G)
BTA: 
282411(CACNA1G)
BOM: 
102280279(CACNA1G)
BIU: 
109574240(CACNA1G)
PHD: 
102338894(CACNA1G)
CHX: 
102187163(CACNA1G)
OAS: 
101117004(CACNA1G)
SSC: 
100513431(CACNA1G)
CFR: 
102516248(CACNA1G)
CDK: 
105097747(CACNA1G)
BACU: 
103001651(CACNA1G)
LVE: 
103083354(CACNA1G)
ECB: 
100070000(CACNA1G)
EPZ: 
103549566(CACNA1G)
EAI: 
106826471(CACNA1G)
MYB: 
102248140(CACNA1G)
MYD: 
102771111(CACNA1G)
HAI: 
109380706(CACNA1G)
RSS: 
109447024(CACNA1G)
PALE: 
102889039(CACNA1G)
LAV: 
100666554(CACNA1G)
MDO: 
100025553(CACNA1G)
SHR: 
100921267(CACNA1G)
OAA: 
GGA: 
769385(CACNA1G)
MGP: 
100551387(CACNA1G)
CJO: 
107322311(CACNA1G)
APLA: 
101800038(CACNA1G)
ACYG: 
106034761(CACNA1G)
TGU: 
100227462(CACNA1G)
GFR: 
102041637(CACNA1G)
FAB: 
101814377(CACNA1G)
PHI: 
102111160(CACNA1G)
PMAJ: 
107212499(CACNA1G)
CCW: 
104694359(CACNA1G)
FPG: 
101917881(CACNA1G)
FCH: 
102053905(CACNA1G)
CLV: 
102088127(CACNA1G)
AAM: 
106485142(CACNA1G)
ASN: 
102382057(CACNA1G)
PSS: 
102454148(CACNA1G)
CMY: 
102947238(CACNA1G)
CPIC: 
101943672(CACNA1G)
ACS: 
100566349(cacna1g)
PVT: 
110091119(CACNA1G)
PBI: 
103052177(CACNA1G)
GJA: 
107110017(CACNA1G)
XLA: 
100462914(cacna1g.L) 108702791
XTR: 
100497283(cacna1g)
NPR: 
108796395(CACNA1G)
DRE: 
563904(cacna1g)
SRX: 
SANH: 
SGH: 
IPU: 
108274069(cacna1g)
AMEX: 
103043155(cacna1g)
TRU: 
TNG: 
LCO: 
104929283(cacna1g)
NCC: 
MZE: 
101479737(cacna1g)
OLA: 
XMA: 
CSEM: 
103382120(cacna1g)
LCF: 
HCQ: 
BPEC: 
SASA: 
ELS: 
105023045(cacna1g)
SFM: 
108939868(cacna1g)
LCM: 
102364726(CACNA1G)
CMK: 
103175750(cacna1g)
SKO: 
DME: 
Dmel_CG15899(Ca-alpha1T)
DPO: 
DAN: 
DER: 
DSE: 
DSI: 
Dsimw501_GD16210(Dsim_GD16210)
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
MDE: 
AGA: 
AAG: 
AME: 
551883(Cav3)
BIM: 
BTER: 
SOC: 
AEC: 
ACEP: 
PBAR: 
CFO: 
LHU: 
PGC: 
NVI: 
TCA: 
DPA: 
NVL: 
BMOR: 
DPL: 
PXY: 
API: 
DNX: 
PHU: 
FCD: 
DPX: 
ISC: 
TUT: 
CEL: 
CBR: 
CBG16834(Cbr-cca-1)
NAI: 
BMY: 
LOA: 
HRO: 
LGI: 
CRG: 
OBI: 
LAK: 
ADF: 
MNG: 
SRE: 
GTT: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Emerick MC, Stein R, Kunze R, McNulty MM, Regan MR, Hanck DA, Agnew WS
  Title
Profiling the array of Ca(v)3.1 variants from the human T-type calcium channel gene CACNA1G: alternative structures, developmental expression, and biophysical variations.
  Journal
Proteins 64:320-42 (2006)
DOI:10.1002/prot.20877
  Sequence
[hsa:8913]

DBGET integrated database retrieval system