KEGG   ORTHOLOGY: K04353Help
Entry
K04353                      KO                                     

Name
RAP1A
Definition
Ras-related protein Rap-1A
Pathway
MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
cAMP signaling pathway
Chemokine signaling pathway
Focal adhesion
Tight junction
Platelet activation
Leukocyte transendothelial migration
Long-term potentiation
Neurotrophin signaling pathway
Pancreatic secretion
Renal cell carcinoma
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    K04353  RAP1A; Ras-related protein Rap-1A
   04015 Rap1 signaling pathway
    K04353  RAP1A; Ras-related protein Rap-1A
   04010 MAPK signaling pathway
    K04353  RAP1A; Ras-related protein Rap-1A
   04024 cAMP signaling pathway
    K04353  RAP1A; Ras-related protein Rap-1A
 Cellular Processes
  Cellular community - eukaryotes
   04510 Focal adhesion
    K04353  RAP1A; Ras-related protein Rap-1A
   04530 Tight junction
    K04353  RAP1A; Ras-related protein Rap-1A
 Organismal Systems
  Immune system
   04611 Platelet activation
    K04353  RAP1A; Ras-related protein Rap-1A
   04670 Leukocyte transendothelial migration
    K04353  RAP1A; Ras-related protein Rap-1A
   04062 Chemokine signaling pathway
    K04353  RAP1A; Ras-related protein Rap-1A
  Digestive system
   04972 Pancreatic secretion
    K04353  RAP1A; Ras-related protein Rap-1A
  Nervous system
   04720 Long-term potentiation
    K04353  RAP1A; Ras-related protein Rap-1A
   04722 Neurotrophin signaling pathway
    K04353  RAP1A; Ras-related protein Rap-1A
 Human Diseases
  Cancers
   05211 Renal cell carcinoma
    K04353  RAP1A; Ras-related protein Rap-1A
GTP-binding proteins [BR:ko04031]
 Small (Monomeric) G-proteins
  Ras Family
   Rap [OT]
    K04353  RAP1A; Ras-related protein Rap-1A
BRITE hierarchy
Genes
HSA: 
5906(RAP1A)
PTR: 
469408(RAP1A)
PPS: 
100980934(RAP1A)
GGO: 
101125618(RAP1A)
PON: 
100433839(RAP1A)
NLE: 
100603891(RAP1A)
MCC: 
704404(RAP1A)
MCF: 
102144586(RAP1A)
CSAB: 
103224221(RAP1A)
RRO: 
104658932(RAP1A)
RBB: 
CJC: 
100393183(RAP1A)
SBQ: 
101048450(RAP1A)
MMU: 
109905(Rap1a)
RNO: 
295347(Rap1a)
CGE: 
100751497(Rap1a)
NGI: 
103734905(Rap1a)
HGL: 
101698757(Rap1a)
CCAN: 
109695156(Rap1a)
OCU: 
100351588(RAP1A)
TUP: 
102475072(RAP1A)
CFA: 
483225(RAP1A)
AML: 
100471801(RAP1A)
UMR: 
103675043(RAP1A)
ORO: 
101375466(RAP1A)
FCA: 
101094942(RAP1A)
PTG: 
102963243(RAP1A)
AJU: 
106969628(RAP1A)
BTA: 
282031(RAP1A)
BOM: 
102286224(RAP1A)
BIU: 
109555931(RAP1A)
PHD: 
102344648(RAP1A)
CHX: 
102176930(RAP1A)
OAS: 
101115080(RAP1A)
SSC: 
100153199(RAP1A)
CFR: 
102516450(RAP1A)
CDK: 
105102039(RAP1A)
BACU: 
103017880(RAP1A)
LVE: 
103069239(RAP1A)
ECB: 
EPZ: 
103547802(RAP1A)
EAI: 
106828599(RAP1A)
MYB: 
102258771(RAP1A)
MYD: 
102774675(RAP1A)
HAI: 
109373546(RAP1A)
RSS: 
109446732(RAP1A)
PALE: 
102879271(RAP1A)
LAV: 
100676220(RAP1A)
TMU: 
MDO: 
100033128(RAP1A)
SHR: 
100935403(RAP1A)
GGA: 
419867(RAP1A)
MGP: 
100151696(RAP1A)
CJO: 
107324916(RAP1A)
APLA: 
101800296(RAP1A)
ACYG: 
106041314(RAP1A)
TGU: 
100151697(RAP1A)
GFR: 
102036447(RAP1A)
FAB: 
101806584(RAP1A)
PHI: 
102112636(RAP1A)
PMAJ: 
107214847(RAP1A)
CCW: 
104692321(RAP1A)
FPG: 
101924077(RAP1A)
FCH: 
102052801(RAP1A)
CLV: 
102089030(RAP1A)
EGZ: 
104126794(RAP1A)
AAM: 
106485263(RAP1A)
ASN: 
102385556(RAP1A)
AMJ: 
102571106(RAP1A)
PSS: 
102461781(RAP1A)
CMY: 
102948045(RAP1A)
CPIC: 
101952443(RAP1A)
ACS: 
100556443(rap1a)
PVT: 
110072354(RAP1A)
PBI: 
103065471(RAP1A)
GJA: 
107112269(RAP1A)
XLA: 
414290(rap1a) 779127(rap1a.L) 780738
XTR: 
100124947(rap1a)
NPR: 
108789680(RAP1A)
DRE: 
406714(rap1ab) 415242(rap1aa)
SRX: 
SANH: 
SGH: 
CCAR: 
IPU: 
108255244(rap1b) 108265690(rap1a)
AMEX: 
TRU: 
TNG: 
LCO: 
NCC: 
MZE: 
OLA: 
XMA: 
PRET: 
CSEM: 
LCF: 
HCQ: 
BPEC: 
SASA: 
106566052(RAP1A) 106567206(RAP1B) 106572472(RAP1B) 106582744(RAP1B)
ELS: 
105023688(rap1a)
SFM: 
LCM: 
102354992(RAP1A)
CMK: 
103182425(rap1a)
CIN: 
445785(rap1b)
SPU: 
APLC: 
DME: 
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
MDE: 
AGA: 
AAG: 
CQU: 
AME: 
BIM: 
BTER: 
SOC: 
AEC: 
ACEP: 
PBAR: 
HST: 
CFO: 
LHU: 
PGC: 
NVI: 
TCA: 
DPA: 
NVL: 
BMOR: 
692519(Ras3)
DPL: 
PMAC: 
PXY: 
API: 
DNX: 
PHU: 
ZNE: 
FCD: 
DPX: 
ISC: 
TUT: 
CEL: 
CBR: 
CBG21720(Cbr-rap-1)
NAI: 
BMY: 
LOA: 
TSP: 
HRO: 
LGI: 
OBI: 
SMM: 
SHX: 
NVE: 
EPA: 
ADF: 
TMS: 
SHS: 
HIR: 
FME: 
LBC: 
MRR: 
CCI: 
SCM: 
WSE: 
DDI: 
DPP: 
DFA: 
EHI: 
EHI_004860(203.t00010) EHI_058090(179.t00009) EHI_101260(5.t00090)
EDI: 
EIV: 
ACAN: 
NGR: 
TVA: 
 » show all
TaxonomyKoalaUniProt
Reference
PMID:2642744
  Authors
Kitayama H, Sugimoto Y, Matsuzaki T, Ikawa Y, Noda M
  Title
A ras-related gene with transformation suppressor activity.
  Journal
Cell 56:77-84 (1989)
DOI:10.1016/0092-8674(89)90985-9
  Sequence
[hsa:5906]

KEGG   ORTHOLOGY: K07836Help
Entry
K07836                      KO                                     

Name
RAP1B
Definition
Ras-related protein Rap-1B
Pathway
MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
cAMP signaling pathway
Chemokine signaling pathway
Focal adhesion
Platelet activation
Leukocyte transendothelial migration
Long-term potentiation
Neurotrophin signaling pathway
Pancreatic secretion
Renal cell carcinoma
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    K07836  RAP1B; Ras-related protein Rap-1B
   04015 Rap1 signaling pathway
    K07836  RAP1B; Ras-related protein Rap-1B
   04010 MAPK signaling pathway
    K07836  RAP1B; Ras-related protein Rap-1B
   04024 cAMP signaling pathway
    K07836  RAP1B; Ras-related protein Rap-1B
 Cellular Processes
  Cellular community - eukaryotes
   04510 Focal adhesion
    K07836  RAP1B; Ras-related protein Rap-1B
 Organismal Systems
  Immune system
   04611 Platelet activation
    K07836  RAP1B; Ras-related protein Rap-1B
   04670 Leukocyte transendothelial migration
    K07836  RAP1B; Ras-related protein Rap-1B
   04062 Chemokine signaling pathway
    K07836  RAP1B; Ras-related protein Rap-1B
  Digestive system
   04972 Pancreatic secretion
    K07836  RAP1B; Ras-related protein Rap-1B
  Nervous system
   04720 Long-term potentiation
    K07836  RAP1B; Ras-related protein Rap-1B
   04722 Neurotrophin signaling pathway
    K07836  RAP1B; Ras-related protein Rap-1B
 Human Diseases
  Cancers
   05211 Renal cell carcinoma
    K07836  RAP1B; Ras-related protein Rap-1B
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   K07836  RAP1B; Ras-related protein Rap-1B
  Exosomal proteins of other body fluids (saliva and urine)
   K07836  RAP1B; Ras-related protein Rap-1B
  Exosomal proteins of colorectal cancer cells
   K07836  RAP1B; Ras-related protein Rap-1B
GTP-binding proteins [BR:ko04031]
 Small (Monomeric) G-proteins
  Ras Family
   Rap [OT]
    K07836  RAP1B; Ras-related protein Rap-1B
BRITE hierarchy
Genes
HSA: 
5908(RAP1B)
PTR: 
452065(RAP1B)
PPS: 
100995578(RAP1B)
GGO: 
101125880(RAP1B)
PON: 
100171907(RAP1B)
NLE: 
100593411(RAP1B)
MCC: 
693750 718171(RAP1B)
MCF: 
102133022(RAP1B)
CSAB: 
RRO: 
104658672(RAP1B)
RBB: 
108532250(RAP1B)
CJC: 
SBQ: 
101036065(RAP1B)
MMU: 
215449(Rap1b)
RNO: 
171337(Rap1b)
CGE: 
100769542(Rap1b)
NGI: 
103745076(Rap1b)
HGL: 
CCAN: 
OCU: 
100339891(RAP1B)
TUP: 
102472381(RAP1B)
CFA: 
608981(RAP1B)
AML: 
100480240(RAP1B)
UMR: 
ORO: 
101383971(RAP1B)
FCA: 
101095993(RAP1B)
PTG: 
102965011(RAP1B)
AJU: 
106966345(RAP1B)
BTA: 
327708(RAP1B) 789148
BOM: 
BIU: 
109559248(RAP1B)
PHD: 
102341520(RAP1B)
CHX: 
102174543(RAP1B)
OAS: 
101106317(RAP1B)
SSC: 
100152555(RAP1B)
CFR: 
102524037(RAP1B)
CDK: 
105101089(RAP1B)
BACU: 
LVE: 
ECB: 
100052025(RAP1B)
EPZ: 
103558687(RAP1B)
EAI: 
106843586(RAP1B)
MYB: 
102254910(RAP1B)
MYD: 
102772411(RAP1B)
HAI: 
109381707(RAP1B)
RSS: 
109456591(RAP1B)
PALE: 
102883778(RAP1B)
LAV: 
100665185(RAP1B)
TMU: 
MDO: 
100014092(RAP1B)
SHR: 
100920135(RAP1B)
OAA: 
100079331(RAP1B)
GGA: 
417840(RAP1B)
MGP: 
100543810(RAP1B)
CJO: 
107310547(RAP1B)
APLA: 
101789925(RAP1B)
ACYG: 
106046993(RAP1B)
TGU: 
100223739(RAP1B)
GFR: 
102042554(RAP1B)
FAB: 
101812484(RAP1B)
PHI: 
102099438(RAP1B)
PMAJ: 
107204636(RAP1B)
CCW: 
104698372(RAP1B)
FPG: 
101924298(RAP1B)
FCH: 
102047995(RAP1B)
CLV: 
102083646(RAP1B)
EGZ: 
104132908(RAP1B)
AAM: 
106488632(RAP1B)
ASN: 
102382819(RAP1B)
AMJ: 
102561548(RAP1B)
PSS: 
102444055(RAP1B)
CMY: 
102947916(RAP1B)
CPIC: 
101935007(RAP1B)
ACS: 
100553457(rap1b)
PVT: 
110075099(RAP1B)
PBI: 
103064511(RAP1B)
GJA: 
107105721(RAP1B)
XLA: 
108713157 379883(rap1b.L)
XTR: 
493557(rap1b)
NPR: 
108804561(RAP1B)
DRE: 
321107(rap1b)
SRX: 
SANH: 
SGH: 
107553881(rap1b)
CCAR: 
IPU: 
100528315(rap1b)
AMEX: 
103035254(rap1b)
TRU: 
TNG: 
LCO: 
104935802(rap1b)
MZE: 
101471329(rap1b)
OLA: 
XMA: 
PRET: 
CSEM: 
LCF: 
108901386(rap1b)
HCQ: 
109532657(rap1b)
BPEC: 
110161898(rap1b)
SASA: 
ELS: 
105017798(rap1b) 105022336(rap1b)
SFM: 
LCM: 
102354357(RAP1B)
CMK: 
103186117(rap1b)
BFO: 
SKO: 
CRG: 
LAK: 
SMM: 
SHX: 
OVI: 
TAD: 
AQU: 
SCE: 
YGR152C(RSR1)
AGO: 
ERC: 
KLA: 
LTH: 
VPO: 
ZRO: 
CGR: 
NCS: 
NCAS_0A01890(NCAS0A01890)
NDI: 
NDAI_0D03820(NDAI0D03820)
TPF: 
TPHA_0K01820(TPHA0K01820)
TBL: 
TBLA_0B00370(TBLA0B00370)
TDL: 
TDEL_0F02770(TDEL0F02770)
KAF: 
KAFR_0F03670(KAFR0F03670)
PPA: 
DHA: 
PIC: 
PGU: 
SPAA: 
LEL: 
CAL: 
CTP: 
COT: 
CDU: 
CTEN: 
YLI: 
CLU: 
CLUS: 
CAUR: 
ZTR: 
PCO: 
MBR: 
SRE: 
DDI: 
DPP: 
DFA: 
ACAN: 
NGR: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Zwartkruis FJ, Bos JL
  Title
Ras and Rap1: two highly related small GTPases with distinct function.
  Journal
Exp Cell Res 253:157-65 (1999)
DOI:10.1006/excr.1999.4695

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