KEGG   ORTHOLOGY: K04357Help
Entry
K04357                      KO                                     

Name
EGF
Definition
epidermal growth factor
Pathway
ko01521  EGFR tyrosine kinase inhibitor resistance
ko04010  MAPK signaling pathway
ko04012  ErbB signaling pathway
ko04014  Ras signaling pathway
ko04015  Rap1 signaling pathway
ko04060  Cytokine-cytokine receptor interaction
ko04066  HIF-1 signaling pathway
ko04068  FoxO signaling pathway
ko04072  Phospholipase D signaling pathway
ko04151  PI3K-Akt signaling pathway
ko04510  Focal adhesion
ko04540  Gap junction
ko04630  Jak-STAT signaling pathway
ko04810  Regulation of actin cytoskeleton
ko05160  Hepatitis C
ko05165  Human papillomavirus infection
ko05200  Pathways in cancer
ko05210  Colorectal cancer
ko05212  Pancreatic cancer
ko05213  Endometrial cancer
ko05214  Glioma
ko05215  Prostate cancer
ko05218  Melanoma
ko05219  Bladder cancer
ko05223  Non-small cell lung cancer
ko05224  Breast cancer
ko05226  Gastric cancer
ko05231  Choline metabolism in cancer
Disease
H00020  Colorectal cancer
H01210  Hypomagnesemia
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    K04357  EGF; epidermal growth factor
   04015 Rap1 signaling pathway
    K04357  EGF; epidermal growth factor
   04010 MAPK signaling pathway
    K04357  EGF; epidermal growth factor
   04012 ErbB signaling pathway
    K04357  EGF; epidermal growth factor
   04630 Jak-STAT signaling pathway
    K04357  EGF; epidermal growth factor
   04066 HIF-1 signaling pathway
    K04357  EGF; epidermal growth factor
   04068 FoxO signaling pathway
    K04357  EGF; epidermal growth factor
   04072 Phospholipase D signaling pathway
    K04357  EGF; epidermal growth factor
   04151 PI3K-Akt signaling pathway
    K04357  EGF; epidermal growth factor
  Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K04357  EGF; epidermal growth factor
 Cellular Processes
  Cellular community - eukaryotes
   04510 Focal adhesion
    K04357  EGF; epidermal growth factor
   04540 Gap junction
    K04357  EGF; epidermal growth factor
  Cell motility
   04810 Regulation of actin cytoskeleton
    K04357  EGF; epidermal growth factor
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K04357  EGF; epidermal growth factor
   05231 Choline metabolism in cancer
    K04357  EGF; epidermal growth factor
   05210 Colorectal cancer
    K04357  EGF; epidermal growth factor
   05212 Pancreatic cancer
    K04357  EGF; epidermal growth factor
   05226 Gastric cancer
    K04357  EGF; epidermal growth factor
   05214 Glioma
    K04357  EGF; epidermal growth factor
   05218 Melanoma
    K04357  EGF; epidermal growth factor
   05219 Bladder cancer
    K04357  EGF; epidermal growth factor
   05215 Prostate cancer
    K04357  EGF; epidermal growth factor
   05213 Endometrial cancer
    K04357  EGF; epidermal growth factor
   05224 Breast cancer
    K04357  EGF; epidermal growth factor
   05223 Non-small cell lung cancer
    K04357  EGF; epidermal growth factor
  Infectious diseases
   05160 Hepatitis C
    K04357  EGF; epidermal growth factor
   05165 Human papillomavirus infection
    K04357  EGF; epidermal growth factor
  Drug resistance
   01521 EGFR tyrosine kinase inhibitor resistance
    K04357  EGF; epidermal growth factor
Cytokines and growth factors [BR:ko04052]
 Growth factors
  Growth factors (RTK binding)
   K04357  EGF; epidermal growth factor
BRITE hierarchy
Other DBs
GO: 0005155
Genes
HSA: 1950(EGF)
PTR: 461435(EGF)
PPS: 100975632(EGF)
GGO: 101153700(EGF)
PON: 100455021(EGF)
NLE: 100588963(EGF)
MCC: 698619(EGF)
MCF: 102123415(EGF)
CSAB: 103236114(EGF)
RRO: 104682421(EGF)
RBB: 108541026(EGF)
CJC: 100388651(EGF)
SBQ: 101052478(EGF)
MMU: 13645(Egf)
RNO: 25313(Egf)
CGE: 100763146(Egf)
NGI: 103742642(Egf)
HGL: 101704789 106007527(Egf)
CCAN: 109700925(Egf)
OCU: 100008808(EGF)
TUP: 102490423(EGF)
CFA: 403657(EGF)
AML: 100467733(EGF)
UMR: 103661742(EGF)
ORO: 101377629(EGF)
FCA: 493978(EGF)
PTG: 102959656(EGF)
AJU: 106983657(EGF)
BTA: 530315(EGF)
BOM: 102285914(EGF)
BIU: 109559983(EGF)
PHD: 102335984(EGF)
CHX: 106502173(EGF)
OAS: 105614258(EGF)
SSC: 397083(EGF)
CFR: 102523769(EGF) 106728895
CDK: 105089905(EGF)
BACU: 103004366(EGF)
LVE: 103073883(EGF)
OOR: 101283152(EGF)
ECB: 106782874(EGF)
EPZ: 103543333 103567315(EGF)
EAI: 106829795(EGF)
MYB: 102264252(EGF)
MYD: 102758044(EGF)
HAI: 109379436(EGF)
RSS: 109452768(EGF)
PALE: 102891552(EGF)
LAV: 100670137(EGF)
TMU: 101355971
MDO: 100619143(EGF)
SHR: 100933169(EGF)
OAA: 100074960(EGF)
GGA: 408035(EGF)
MGP: 100543460(EGF)
CJO: 107313609(EGF)
APLA: 101795002(EGF)
ACYG: 106038683(EGF)
TGU: 100218747(EGF)
GFR: 102034269(EGF)
FAB: 101819290(EGF)
PHI: 102112980(EGF)
PMAJ: 107203603(EGF)
CCW: 104697130(EGF)
FPG: 101916879(EGF)
FCH: 102049265(EGF)
CLV: 102083886(EGF)
EGZ: 104135535(EGF)
AAM: 106491937(EGF)
ASN: 102388605(EGF)
AMJ: 102560233(EGF)
PSS: 102453328(EGF)
CMY: 102933086(EGF)
CPIC: 101934754(EGF)
ACS: 100562822(egf)
PVT: 110087292(EGF)
PBI: 103061516(EGF)
GJA: 107122699(EGF)
XLA: 108704401 108710179(egf.L)
XTR: 100127663(egf)
NPR: 108798307(EGF)
DRE: 403045(egf)
IPU: 108268549(egf)
AMEX: 103045727(egf)
TRU: 101061284(egf)
LCO: 104917921(egf)
NCC: 104953729(egf)
MZE: 101487082(egf)
OLA: 101167023(egf)
XMA: 102219388(egf)
PRET: 103471828(egf)
NFU: 107374766(egf)
CSEM: 103390644(egf)
LCF: 108885177(egf)
HCQ: 109524192(egf)
BPEC: 110153711(egf)
SASA: 106611584(egf)
ELS: 105027559(egf)
SFM: 108938717(egf)
LCM: 102348800 102356822(EGF)
CMK: 103180890(egf)
SKO: 102807105
ADF: 107331023
 » show all
TaxonomyKoalaUniProt
Reference
PMID:3491360
  Authors
Bell GI, Fong NM, Stempien MM, Wormsted MA, Caput D, Ku LL, Urdea MS, Rall LB, Sanchez-Pescador R
  Title
Human epidermal growth factor precursor: cDNA sequence, expression in vitro and gene organization.
  Journal
Nucleic Acids Res 14:8427-46 (1986)
DOI:10.1093/nar/14.21.8427
  Sequence
[hsa:1950]
Reference
  Authors
Hermann PM, van Kesteren RE, Wildering WC, Painter SD, Reno JM, Smith JS, Kumar SB, Geraerts WP, Ericsson LH, Smit AB, Bulloch AG, Nagle GT
  Title
Neurotrophic actions of a novel molluscan epidermal growth factor.
  Journal
J Neurosci 20:6355-64 (2000)
  Sequence
[mmu:13645]

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