KEGG   ORTHOLOGY: K04362Help
Entry
K04362                      KO                                     

Name
FGFR1, CD331
Definition
fibroblast growth factor receptor 1 [EC:2.7.10.1]
Pathway
MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
PI3K-Akt signaling pathway
Adherens junction
Signaling pathways regulating pluripotency of stem cells
Regulation of actin cytoskeleton
Pathways in cancer
Proteoglycans in cancer
Prostate cancer
Melanoma
Breast cancer
Central carbon metabolism in cancer
Disease
H00031  
Breast cancer
H00255  
Hypogonadotropic hypogonadism
H00443  
Osteoglophonic dysplasia (OD)
H00458  
Craniosynostosis
H00516  
Cleft lip and/or cleft palate
H01207  
Trigonocephaly
H01756  
Pfeiffer syndrome
H01850  
Hartsfield syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    K04362  FGFR1, CD331; fibroblast growth factor receptor 1
   04015 Rap1 signaling pathway
    K04362  FGFR1, CD331; fibroblast growth factor receptor 1
   04010 MAPK signaling pathway
    K04362  FGFR1, CD331; fibroblast growth factor receptor 1
   04151 PI3K-Akt signaling pathway
    K04362  FGFR1, CD331; fibroblast growth factor receptor 1
 Cellular Processes
  Cellular community - eukaryotes
   04520 Adherens junction
    K04362  FGFR1, CD331; fibroblast growth factor receptor 1
   04550 Signaling pathways regulating pluripotency of stem cells
    K04362  FGFR1, CD331; fibroblast growth factor receptor 1
  Cell motility
   04810 Regulation of actin cytoskeleton
    K04362  FGFR1, CD331; fibroblast growth factor receptor 1
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K04362  FGFR1, CD331; fibroblast growth factor receptor 1
   05230 Central carbon metabolism in cancer
    K04362  FGFR1, CD331; fibroblast growth factor receptor 1
   05205 Proteoglycans in cancer
    K04362  FGFR1, CD331; fibroblast growth factor receptor 1
   05218 Melanoma
    K04362  FGFR1, CD331; fibroblast growth factor receptor 1
   05215 Prostate cancer
    K04362  FGFR1, CD331; fibroblast growth factor receptor 1
   05224 Breast cancer
    K04362  FGFR1, CD331; fibroblast growth factor receptor 1
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     K04362  FGFR1, CD331; fibroblast growth factor receptor 1
Protein kinases [BR:ko01001]
 Tyrosine protein kinases
  FGFR family [OT]
   K04362  FGFR1, CD331; fibroblast growth factor receptor 1
Enzyme-linked receptors [BR:ko01020]
 Receptor tyrosine kinases
  RTK class IV (FGF receptor family)
   K04362  FGFR1, CD331; fibroblast growth factor receptor 1
Cytokine receptors [BR:ko04050]
 Receptor tyrosine kinase
  RTK class IV (FGF receptor family)
   K04362  FGFR1, CD331; fibroblast growth factor receptor 1
Cell adhesion molecules and their ligands [BR:ko04516]
 1. Immunoglobulin Superfamily
  Neural system
   5/2 subfamily
    NCAM; neural cell adhesion molecule
     K04362 FGFR1, CD331; fibroblast growth factor receptor 1
   6/5 subfamily
    L1CAM; L1 cell adhesion molecule
     K04362 FGFR1, CD331; fibroblast growth factor receptor 1
 5. Cadherin Family
  Classic Cadherins
   Vertebrate Type I classic cadherins
    CDH2; cadherin 2, type 1, N-cadherin
     K04362 FGFR1, CD331; fibroblast growth factor receptor 1
CD molecules [BR:ko04090]
 Proteins
  K04362  CD331, FGFR1; fibroblast growth factor receptor 1
Glycosaminoglycan binding proteins [BR:ko00536]
 Heparan sulfate/Haparin
  Growth factors/receptors
   K04362  FGFR1, CD331; fibroblast growth factor receptor 1
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
2260(FGFR1)
PTR: 
464122(FGFR1)
PPS: 
100988115(FGFR1)
GGO: 
101152179(FGFR1)
PON: 
100174545(FGFR1)
NLE: 
100602423(FGFR1)
MCC: 
700126(FGFR1)
MCF: 
102144714(FGFR1)
CSAB: 
103215648(FGFR1)
RRO: 
104679640(FGFR1)
RBB: 
108512401(FGFR1)
CJC: 
100390192(FGFR1)
SBQ: 
101033213(FGFR1)
MMU: 
14182(Fgfr1)
RNO: 
79114(Fgfr1)
CGE: 
100773586(Fgfr1)
NGI: 
103745770(Fgfr1)
HGL: 
101700324(Fgfr1)
CCAN: 
109688936(Fgfr1)
OCU: 
100351861(FGFR1)
TUP: 
102484087(FGFR1)
CFA: 
100856477(FGFR1)
AML: 
100472630(FGFR1)
UMR: 
103659146(FGFR1)
FCA: 
101086055(FGFR1)
PTG: 
102972346(FGFR1)
AJU: 
106978376(FGFR1)
BTA: 
281768(FGFR1)
BOM: 
102267776(FGFR1)
BIU: 
109553304(FGFR1)
PHD: 
102315245(FGFR1)
CHX: 
102180282(FGFR1)
OAS: 
780507(FGFR1)
SSC: 
100153248(FGFR1)
CFR: 
102515264(FGFR1)
CDK: 
105105270(FGFR1)
BACU: 
103017733(FGFR1)
LVE: 
103069902(FGFR1)
ECB: 
100057614(FGFR1)
EPZ: 
103560266(FGFR1)
EAI: 
106824659(FGFR1)
MYB: 
102253832(FGFR1)
MYD: 
102759202(FGFR1)
HAI: 
109373149(FGFR1)
RSS: 
109456079(FGFR1)
PALE: 
102898943(FGFR1)
LAV: 
100662289(FGFR1)
MDO: 
100029852(FGFR1)
SHR: 
100914347(FGFR1)
OAA: 
100074240(FGFR1)
GGA: 
396516(FGFR1)
MGP: 
100547498(FGFR1)
CJO: 
107323773(FGFR1)
APLA: 
101799290(FGFR1)
ACYG: 
106044374(FGFR1)
TGU: 
100221243(FGFR1)
GFR: 
FAB: 
101822220(FGFR1)
PHI: 
102103637(FGFR1)
PMAJ: 
107213845(FGFR1)
CCW: 
104694904(FGFR1)
FPG: 
101914093(FGFR1)
FCH: 
102055369(FGFR1)
CLV: 
102085235(FGFR1)
AAM: 
106492992(FGFR1)
ASN: 
102386174(FGFR1)
AMJ: 
102574117(FGFR1)
PSS: 
102461506(FGFR1)
CMY: 
CPIC: 
101941076(FGFR1)
ACS: 
100559018(fgfr1)
PVT: 
110072166(FGFR1)
PBI: 
103066603(FGFR1)
GJA: 
107113006(FGFR1)
XLA: 
394418(fgfr1.L) 397782(xfgfra2) 399444(fgfr1.S)
XTR: 
548648(fgfr1)
NPR: 
108791453(FGFR1)
DRE: 
30705(fgfr1a)
SRX: 
SANH: 
SGH: 
IPU: 
AMEX: 
TRU: 
TNG: 
LCO: 
NCC: 
MZE: 
OLA: 
XMA: 
CSEM: 
LCF: 
HCQ: 
BPEC: 
SASA: 
ELS: 
SFM: 
LCM: 
102361014(FGFR1)
CMK: 
BFO: 
CIN: 
445706(fgfr)
SPU: 
373310(FGFR)
APLC: 
SKO: 
NVI: 
API: 
FCD: 
DPX: 
TUT: 
TSP: 
HRO: 
LGI: 
MYI: 
OBI: 
LAK: 
OVI: 
EPA: 
ADF: 
AQU: 
SRE: 
 » show all
TaxonomyKoalaUniProt
Reference
PMID:1697263
  Authors
Dionne CA, Crumley G, Bellot F, Kaplow JM, Searfoss G, Ruta M, Burgess WH, Jaye M, Schlessinger J
  Title
Cloning and expression of two distinct high-affinity receptors cross-reacting with acidic and basic fibroblast growth factors.
  Journal
EMBO J 9:2685-92 (1990)
  Sequence
[hsa:2260]

KEGG   ORTHOLOGY: K05093Help
Entry
K05093                      KO                                     

Name
FGFR2, CD332
Definition
fibroblast growth factor receptor 2 [EC:2.7.10.1]
Pathway
EGFR tyrosine kinase inhibitor resistance
MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
Endocytosis
PI3K-Akt signaling pathway
Signaling pathways regulating pluripotency of stem cells
Regulation of actin cytoskeleton
Pathways in cancer
Prostate cancer
Gastric cancer
Central carbon metabolism in cancer
Disease
H00018  
Gastric cancer
H00458  
Craniosynostosis
H00642  
Lacrimo-auriculo-dento-digital syndrome (LADD)
H01753  
Antley-Bixler syndrome
H01754  
Crouzon syndrome
H01755  
Apert syndrome
H01756  
Pfeiffer syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    K05093  FGFR2, CD332; fibroblast growth factor receptor 2
   04015 Rap1 signaling pathway
    K05093  FGFR2, CD332; fibroblast growth factor receptor 2
   04010 MAPK signaling pathway
    K05093  FGFR2, CD332; fibroblast growth factor receptor 2
   04151 PI3K-Akt signaling pathway
    K05093  FGFR2, CD332; fibroblast growth factor receptor 2
 Cellular Processes
  Transport and catabolism
   04144 Endocytosis
    K05093  FGFR2, CD332; fibroblast growth factor receptor 2
  Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    K05093  FGFR2, CD332; fibroblast growth factor receptor 2
  Cell motility
   04810 Regulation of actin cytoskeleton
    K05093  FGFR2, CD332; fibroblast growth factor receptor 2
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K05093  FGFR2, CD332; fibroblast growth factor receptor 2
   05230 Central carbon metabolism in cancer
    K05093  FGFR2, CD332; fibroblast growth factor receptor 2
   05226 Gastric cancer
    K05093  FGFR2, CD332; fibroblast growth factor receptor 2
   05215 Prostate cancer
    K05093  FGFR2, CD332; fibroblast growth factor receptor 2
  Drug resistance
   01521 EGFR tyrosine kinase inhibitor resistance
    K05093  FGFR2, CD332; fibroblast growth factor receptor 2
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     K05093  FGFR2, CD332; fibroblast growth factor receptor 2
Protein kinases [BR:ko01001]
 Tyrosine protein kinases
  FGFR family [OT]
   K05093  FGFR2, CD332; fibroblast growth factor receptor 2
Enzyme-linked receptors [BR:ko01020]
 Receptor tyrosine kinases
  RTK class IV (FGF receptor family)
   K05093  FGFR2, CD332; fibroblast growth factor receptor 2
Cytokine receptors [BR:ko04050]
 Receptor tyrosine kinase
  RTK class IV (FGF receptor family)
   K05093  FGFR2, CD332; fibroblast growth factor receptor 2
CD molecules [BR:ko04090]
 Proteins
  K05093  CD332, FGFR2; fibroblast growth factor receptor 2
Glycosaminoglycan binding proteins [BR:ko00536]
 Heparan sulfate/Haparin
  Growth factors/receptors
   K05093  FGFR2, CD332; fibroblast growth factor receptor 2
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
2263(FGFR2)
PTR: 
466220(FGFR2)
PPS: 
100981139(FGFR2)
GGO: 
101153046(FGFR2)
PON: 
100171540(FGFR2)
NLE: 
100598157(FGFR2)
MCC: 
715949(FGFR2)
MCF: 
102143086(FGFR2)
CSAB: 
103216628(FGFR2)
RRO: 
104675847(FGFR2)
RBB: 
108529768(FGFR2)
CJC: 
100393573(FGFR2)
SBQ: 
101033845(FGFR2)
MMU: 
14183(Fgfr2)
RNO: 
25022(Fgfr2)
CGE: 
NGI: 
103729272(Fgfr2)
HGL: 
101709077(Fgfr2)
CCAN: 
109691649(Fgfr2)
OCU: 
100009417(FGFR2)
TUP: 
102484403(FGFR2)
CFA: 
415125(FGFR2)
AML: 
100468267(FGFR2)
UMR: 
103657802(FGFR2)
FCA: 
101095198(FGFR2)
PTG: 
102964142(FGFR2)
AJU: 
106969379(FGFR2)
BTA: 
404193(FGFR2)
BOM: 
102270743(FGFR2)
BIU: 
109553142(FGFR2)
PHD: 
102330293(FGFR2)
CHX: 
102170938(FGFR2)
OAS: 
443548(FGFR2)
SSC: 
396762(FGFR2)
CFR: 
102516073(FGFR2)
CDK: 
105104060(FGFR2)
BACU: 
103012184(FGFR2)
LVE: 
103090812(FGFR2)
ECB: 
100033956(FGFR2)
EPZ: 
103547114(FGFR2)
EAI: 
106846935(FGFR2)
MYB: 
102254053(FGFR2)
MYD: 
102763283(FGFR2)
HAI: 
109383003(FGFR2)
RSS: 
109458909(FGFR2)
PALE: 
102882899(FGFR2)
LAV: 
100664128(FGFR2)
MDO: 
100025727(FGFR2)
SHR: 
100932215(FGFR2)
OAA: 
GGA: 
396259(FGFR2)
MGP: 
CJO: 
107316195(FGFR2)
APLA: 
101791540(FGFR2)
ACYG: 
106038987(FGFR2)
TGU: 
100223379(FGFR2)
GFR: 
102038840(FGFR2)
FAB: 
101812169(FGFR2)
PHI: 
102105117(FGFR2)
PMAJ: 
107206911(FGFR2)
CCW: 
104694675(FGFR2)
FPG: 
101913692(FGFR2)
FCH: 
102056102(FGFR2)
CLV: 
102091137(FGFR2)
AAM: 
106499024(FGFR2)
ASN: 
102382394(FGFR2)
AMJ: 
102564591(FGFR2)
PSS: 
102443772(FGFR2)
CMY: 
102938554(FGFR2)
CPIC: 
101933273(FGFR2)
ACS: 
100562611(fgfr2)
PVT: 
110075320(FGFR2)
PBI: 
103057830(FGFR2)
GJA: 
107112647(FGFR2)
XLA: 
108697372(fgfr2.S) 399325(fgfr2.L)
XTR: 
100124910(fgfr2)
NPR: 
108793050(FGFR2)
DRE: 
352940(fgfr2)
SRX: 
SANH: 
SGH: 
IPU: 
108263349(fgfr2)
AMEX: 
TRU: 
101073665(fgfr2)
TNG: 
LCO: 
104925607(fgfr2)
NCC: 
MZE: 
101463957(fgfr2)
OLA: 
XMA: 
CSEM: 
LCF: 
108885762(fgfr2)
HCQ: 
109523130(fgfr2)
BPEC: 
110168143(fgfr2)
SASA: 
ELS: 
105010630(fgfr2)
SFM: 
108925828(fgfr2)
LCM: 
102349925(FGFR2)
CMK: 
BFO: 
APLC: 
SKO: 
DME: 
DPO: 
DAN: 
DER: 
DSE: 
DSI: 
Dsimw501_GD14480(Dsim_GD14480)
DWI: 
DYA: 
DMO: 
DVI: 
MDE: 
AGA: 
CQU: 
AME: 
413200(htl)
BIM: 
BTER: 
SOC: 
AEC: 
ACEP: 
CFO: 
LHU: 
TCA: 
659434(DFR1)
DPA: 
NVL: 
HRO: 
LGI: 
CRG: 
MYI: 
OBI: 
LAK: 
SHX: 
EPA: 
ADF: 
AQU: 
 » show all
TaxonomyKoalaUniProt
Reference
PMID:1697263
  Authors
Dionne CA, Crumley G, Bellot F, Kaplow JM, Searfoss G, Ruta M, Burgess WH, Jaye M, Schlessinger J
  Title
Cloning and expression of two distinct high-affinity receptors cross-reacting with acidic and basic fibroblast growth factors.
  Journal
EMBO J 9:2685-92 (1990)
  Sequence
[hsa:2263]

KEGG   ORTHOLOGY: K05094Help
Entry
K05094                      KO                                     

Name
FGFR3, CD333
Definition
fibroblast growth factor receptor 3 [EC:2.7.10.1]
Pathway
EGFR tyrosine kinase inhibitor resistance
MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
Endocytosis
PI3K-Akt signaling pathway
Signaling pathways regulating pluripotency of stem cells
Regulation of actin cytoskeleton
Pathways in cancer
MicroRNAs in cancer
Bladder cancer
Central carbon metabolism in cancer
Disease
H00010  
Multiple myeloma
H00022  
Bladder cancer
H00458  
Craniosynostosis
H00505  
FGFR3-related short limb skeletal dysplasias
H00642  
Lacrimo-auriculo-dento-digital syndrome (LADD)
H00997  
CATSHL syndrome
H01749  
Achondroplasia
H01750  
Thanatophoric dysplasia
H01754  
Crouzon syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    K05094  FGFR3, CD333; fibroblast growth factor receptor 3
   04015 Rap1 signaling pathway
    K05094  FGFR3, CD333; fibroblast growth factor receptor 3
   04010 MAPK signaling pathway
    K05094  FGFR3, CD333; fibroblast growth factor receptor 3
   04151 PI3K-Akt signaling pathway
    K05094  FGFR3, CD333; fibroblast growth factor receptor 3
 Cellular Processes
  Transport and catabolism
   04144 Endocytosis
    K05094  FGFR3, CD333; fibroblast growth factor receptor 3
  Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    K05094  FGFR3, CD333; fibroblast growth factor receptor 3
  Cell motility
   04810 Regulation of actin cytoskeleton
    K05094  FGFR3, CD333; fibroblast growth factor receptor 3
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K05094  FGFR3, CD333; fibroblast growth factor receptor 3
   05230 Central carbon metabolism in cancer
    K05094  FGFR3, CD333; fibroblast growth factor receptor 3
   05206 MicroRNAs in cancer
    K05094  FGFR3, CD333; fibroblast growth factor receptor 3
   05219 Bladder cancer
    K05094  FGFR3, CD333; fibroblast growth factor receptor 3
  Drug resistance
   01521 EGFR tyrosine kinase inhibitor resistance
    K05094  FGFR3, CD333; fibroblast growth factor receptor 3
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     K05094  FGFR3, CD333; fibroblast growth factor receptor 3
Protein kinases [BR:ko01001]
 Tyrosine protein kinases
  FGFR family [OT]
   K05094  FGFR3, CD333; fibroblast growth factor receptor 3
Enzyme-linked receptors [BR:ko01020]
 Receptor tyrosine kinases
  RTK class IV (FGF receptor family)
   K05094  FGFR3, CD333; fibroblast growth factor receptor 3
Cytokine receptors [BR:ko04050]
 Receptor tyrosine kinase
  RTK class IV (FGF receptor family)
   K05094  FGFR3, CD333; fibroblast growth factor receptor 3
CD molecules [BR:ko04090]
 Proteins
  K05094  CD333, FGFR3; fibroblast growth factor receptor 3
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
2261(FGFR3)
PTR: 
461067(FGFR3)
PPS: 
100976551(FGFR3)
GGO: 
101139997(FGFR3)
PON: 
NLE: 
100591839(FGFR3)
MCC: 
712829(FGFR3)
MCF: 
102128947(FGFR3)
CSAB: 
103246479(FGFR3)
RRO: 
104678934(FGFR3)
RBB: 
108532286(FGFR3)
CJC: 
100409938(FGFR3)
SBQ: 
101051421(FGFR3)
MMU: 
14184(Fgfr3)
RNO: 
84489(Fgfr3)
CGE: 
100764560(Fgfr3)
NGI: 
103741127(Fgfr3)
HGL: 
101711651(Fgfr3)
CCAN: 
109695016(Fgfr3)
TUP: 
102500041(FGFR3)
CFA: 
488808(FGFR3)
AML: 
100481826(FGFR3)
UMR: 
103676958(FGFR3)
FCA: 
100141386(FGFR3)
BTA: 
281769(FGFR3)
BOM: 
102264670(FGFR3)
BIU: 
109560724(FGFR3)
PHD: 
102325791(FGFR3)
CHX: 
102187310(FGFR3)
OAS: 
554324(FGFR3)
SSC: 
100514115(FGFR3)
CFR: 
CDK: 
105100875(FGFR3)
BACU: 
103002473(FGFR3)
LVE: 
103086424(FGFR3)
ECB: 
100034114(FGFR3)
EPZ: 
103556997(FGFR3)
EAI: 
106830606(FGFR3)
HAI: 
109390958(FGFR3)
RSS: 
PALE: 
102878342(FGFR3)
LAV: 
100674054(FGFR3)
MDO: 
100023287(FGFR3)
SHR: 
100913979(FGFR3)
OAA: 
100084071(FGFR3)
GGA: 
396515(FGFR3)
MGP: 
100543461(FGFR3)
CJO: 
107313983(FGFR3)
APLA: 
101804995(FGFR3)
ACYG: 
106034332(FGFR3)
TGU: 
100218924(FGFR3)
GFR: 
102044988(FGFR3)
FAB: 
101812160(FGFR3)
PHI: 
102114034(FGFR3)
PMAJ: 
107203422(FGFR3)
CCW: 
104690922(FGFR3)
FPG: 
101920747(FGFR3)
FCH: 
102052231(FGFR3)
CLV: 
102098275(FGFR3)
AAM: 
106498761(FGFR3)
ASN: 
102371740(FGFR3)
AMJ: 
106736800(FGFR3)
PSS: 
102444715(FGFR3)
CMY: 
102939991(FGFR3)
CPIC: 
101933794(FGFR3)
PVT: 
110085587(FGFR3)
PBI: 
103067086(FGFR3)
GJA: 
XLA: 
399347(fgfr3.S) 779370(fgfr3.L)
XTR: 
100196923(fgfr3)
NPR: 
108788840(FGFR3)
DRE: 
58129(fgfr3)
SRX: 
SANH: 
SGH: 
IPU: 
AMEX: 
103045058(fgfr3)
TRU: 
TNG: 
LCO: 
NCC: 
MZE: 
OLA: 
100049424(fgfr3)
XMA: 
102228238(fgfr3)
CSEM: 
103383204(fgfr3)
LCF: 
108889150(fgfr3)
HCQ: 
109520993(fgfr3)
BPEC: 
110155643(fgfr3)
SASA: 
ELS: 
SFM: 
108920925(fgfr3)
LCM: 
102364583(FGFR3)
CMK: 
103181516(fgfr3)
BFO: 
APLC: 
SKO: 
DME: 
DAN: 
DER: 
DSE: 
DSI: 
Dsimw501_GD20204(Dsim_GD20204)
DYA: 
PXY: 
PHU: 
FCD: 
DPX: 
ISC: 
TUT: 
CRG: 
MYI: 
OBI: 
LAK: 
SMM: 
NVE: 
EPA: 
ADF: 
HMG: 
AQU: 
SRE: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Terada M, Shimizu A, Sato N, Miyakaze SI, Katayama H, Kurokawa-Seo M
  Title
Fibroblast growth factor receptor 3 lacking the Ig IIIb and transmembrane domains secreted from human squamous cell carcinoma DJM-1 binds to FGFs.
  Journal
Mol Cell Biol Res Commun 4:365-73 (2001)
DOI:10.1006/mcbr.2001.0306
  Sequence
[hsa:2261]

KEGG   ORTHOLOGY: K05095Help
Entry
K05095                      KO                                     

Name
FGFR4, CD334
Definition
fibroblast growth factor receptor 4 [EC:2.7.10.1]
Pathway
MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
Endocytosis
PI3K-Akt signaling pathway
Signaling pathways regulating pluripotency of stem cells
Regulation of actin cytoskeleton
Pathways in cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    K05095  FGFR4, CD334; fibroblast growth factor receptor 4
   04015 Rap1 signaling pathway
    K05095  FGFR4, CD334; fibroblast growth factor receptor 4
   04010 MAPK signaling pathway
    K05095  FGFR4, CD334; fibroblast growth factor receptor 4
   04151 PI3K-Akt signaling pathway
    K05095  FGFR4, CD334; fibroblast growth factor receptor 4
 Cellular Processes
  Transport and catabolism
   04144 Endocytosis
    K05095  FGFR4, CD334; fibroblast growth factor receptor 4
  Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    K05095  FGFR4, CD334; fibroblast growth factor receptor 4
  Cell motility
   04810 Regulation of actin cytoskeleton
    K05095  FGFR4, CD334; fibroblast growth factor receptor 4
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K05095  FGFR4, CD334; fibroblast growth factor receptor 4
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     K05095  FGFR4, CD334; fibroblast growth factor receptor 4
Protein kinases [BR:ko01001]
 Tyrosine protein kinases
  FGFR family [OT]
   K05095  FGFR4, CD334; fibroblast growth factor receptor 4
Enzyme-linked receptors [BR:ko01020]
 Receptor tyrosine kinases
  RTK class IV (FGF receptor family)
   K05095  FGFR4, CD334; fibroblast growth factor receptor 4
Cytokine receptors [BR:ko04050]
 Receptor tyrosine kinase
  RTK class IV (FGF receptor family)
   K05095  FGFR4, CD334; fibroblast growth factor receptor 4
Cell adhesion molecules and their ligands [BR:ko04516]
 1. Immunoglobulin Superfamily
  Neural system
   5/2 subfamily
    NCAM; neural cell adhesion molecule
     K05095 FGFR4, CD334; fibroblast growth factor receptor 4
 5. Cadherin Family
  Classic Cadherins
   Vertebrate Type I classic cadherins
    CDH2; cadherin 2, type 1, N-cadherin
     K05095 FGFR4, CD334; fibroblast growth factor receptor 4
CD molecules [BR:ko04090]
 Proteins
  K05095  CD334, FGFR4; fibroblast growth factor receptor 4
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
2264(FGFR4)
PTR: 
462301(FGFR4)
PPS: 
100991315(FGFR4)
GGO: 
101145205(FGFR4)
PON: 
100461105(FGFR4)
NLE: 
100582351(FGFR4)
MCC: 
698494(FGFR4)
MCF: 
102118990(FGFR4)
CSAB: 
103245042(FGFR4)
RRO: 
104680447(FGFR4)
RBB: 
CJC: 
100414348(FGFR4)
SBQ: 
101027585(FGFR4)
MMU: 
14186(Fgfr4)
RNO: 
25114(Fgfr4)
CGE: 
100765320(Fgfr4)
NGI: 
103732354(Fgfr4)
HGL: 
101700214(Fgfr4)
CCAN: 
109685768(Fgfr4)
OCU: 
100355275(FGFR4)
TUP: 
102475159(FGFR4)
CFA: 
489095(FGFR4)
AML: 
100477678(FGFR4)
UMR: 
103664454(FGFR4)
FCA: 
101100864(FGFR4)
PTG: 
102965504(FGFR4)
AJU: 
106975403(FGFR4)
BTA: 
317696(FGFR4)
BOM: 
102267813(FGFR4)
BIU: 
109561893(FGFR4)
PHD: 
102316376(FGFR4)
CHX: 
102183685(FGFR4)
OAS: 
101120660(FGFR4)
SSC: 
100127133(FGFR4)
CFR: 
102510147(FGFR4)
CDK: 
105099582(FGFR4)
BACU: 
103013305(FGFR4)
LVE: 
103078406(FGFR4)
ECB: 
100068679(FGFR4)
EPZ: 
103557327(FGFR4)
EAI: 
106827191(FGFR4)
MYB: 
102258015(FGFR4)
MYD: 
102759469(FGFR4)
HAI: 
109389796(FGFR4)
RSS: 
109434235(FGFR4)
PALE: 
102879288(FGFR4)
LAV: 
100672193(FGFR4)
MDO: 
100031838(FGFR4)
SHR: 
100919819(FGFR4)
GGA: 
395603(FGFR4)
MGP: 
100544316(FGFR4)
CJO: 
107320486(FGFR4)
ACYG: 
106049509(FGFR4)
TGU: 
100226243(FGFR4)
GFR: 
102044508(FGFR4)
FAB: 
101814756(FGFR4)
PHI: 
102109120(FGFR4)
PMAJ: 
107210899(FGFR4)
CCW: 
104689519(FGFR4)
FPG: 
101917722(FGFR4)
FCH: 
102055424(FGFR4)
CLV: 
102085088(FGFR4)
AAM: 
106491594(FGFR4)
ASN: 
102368985(FGFR4)
AMJ: 
102567148(FGFR4)
CMY: 
102930286(FGFR4)
CPIC: 
101931613(FGFR4)
ACS: 
100554153(fgfr4)
PVT: 
110077562(FGFR4)
PBI: 
103052689(FGFR4)
GJA: 
107111538(FGFR4)
XLA: 
397701(fgfr4.L) 398181(fgfr4.S)
XTR: 
549077(fgfr4)
NPR: 
108783764(FGFR4)
DRE: 
100000160(fgfr4)
SRX: 
SANH: 
SGH: 
AMEX: 
103029904(fgfr4)
TNG: 
MZE: 
101477307(fgfr4)
XMA: 
102216451(fgfr4)
CSEM: 
LCF: 
HCQ: 
BPEC: 
SASA: 
ELS: 
105011125(fgfr4)
SFM: 
108920074(fgfr4)
LCM: 
102345296(FGFR4)
AQU: 
 » show all
TaxonomyKoalaUniProt
Reference
PMID:1709094
  Authors
Partanen J, Makela TP, Eerola E, Korhonen J, Hirvonen H, Claesson-Welsh L, Alitalo K
  Title
FGFR-4, a novel acidic fibroblast growth factor receptor with a distinct expression pattern.
  Journal
EMBO J 10:1347-54 (1991)
  Sequence
[hsa:2264]

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