KEGG   ORTHOLOGY: K04379Help
Entry
K04379                      KO                                     

Name
FOS
Definition
proto-oncogene protein c-fos
Pathway
Endocrine resistance
MAPK signaling pathway
cAMP signaling pathway
Apoptosis
Osteoclast differentiation
Toll-like receptor signaling pathway
IL-17 signaling pathway
Th1 and Th2 cell differentiation
Th17 cell differentiation
T cell receptor signaling pathway
B cell receptor signaling pathway
TNF signaling pathway
Circadian entrainment
Cholinergic synapse
Dopaminergic synapse
Estrogen signaling pathway
Prolactin signaling pathway
Oxytocin signaling pathway
Relaxin signaling pathway
Amphetamine addiction
Salmonella infection
Pertussis
Leishmaniasis
Chagas disease (American trypanosomiasis)
Hepatitis B
HTLV-I infection
Kaposi's sarcoma-associated herpesvirus infection
Herpes simplex infection
Pathways in cancer
Colorectal cancer
Breast cancer
Choline metabolism in cancer
Rheumatoid arthritis
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    K04379  FOS; proto-oncogene protein c-fos
   04668 TNF signaling pathway
    K04379  FOS; proto-oncogene protein c-fos
   04024 cAMP signaling pathway
    K04379  FOS; proto-oncogene protein c-fos
 Cellular Processes
  Cell growth and death
   04210 Apoptosis
    K04379  FOS; proto-oncogene protein c-fos
 Organismal Systems
  Immune system
   04620 Toll-like receptor signaling pathway
    K04379  FOS; proto-oncogene protein c-fos
   04660 T cell receptor signaling pathway
    K04379  FOS; proto-oncogene protein c-fos
   04658 Th1 and Th2 cell differentiation
    K04379  FOS; proto-oncogene protein c-fos
   04659 Th17 cell differentiation
    K04379  FOS; proto-oncogene protein c-fos
   04657 IL-17 signaling pathway
    K04379  FOS; proto-oncogene protein c-fos
   04662 B cell receptor signaling pathway
    K04379  FOS; proto-oncogene protein c-fos
  Endocrine system
   04915 Estrogen signaling pathway
    K04379  FOS; proto-oncogene protein c-fos
   04917 Prolactin signaling pathway
    K04379  FOS; proto-oncogene protein c-fos
   04921 Oxytocin signaling pathway
    K04379  FOS; proto-oncogene protein c-fos
   04926 Relaxin signaling pathway
    K04379  FOS; proto-oncogene protein c-fos
  Nervous system
   04725 Cholinergic synapse
    K04379  FOS; proto-oncogene protein c-fos
   04728 Dopaminergic synapse
    K04379  FOS; proto-oncogene protein c-fos
  Development
   04380 Osteoclast differentiation
    K04379  FOS; proto-oncogene protein c-fos
  Environmental adaptation
   04713 Circadian entrainment
    K04379  FOS; proto-oncogene protein c-fos
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K04379  FOS; proto-oncogene protein c-fos
   05231 Choline metabolism in cancer
    K04379  FOS; proto-oncogene protein c-fos
   05210 Colorectal cancer
    K04379  FOS; proto-oncogene protein c-fos
   05224 Breast cancer
    K04379  FOS; proto-oncogene protein c-fos
  Immune diseases
   05323 Rheumatoid arthritis
    K04379  FOS; proto-oncogene protein c-fos
  Substance dependence
   05031 Amphetamine addiction
    K04379  FOS; proto-oncogene protein c-fos
  Cardiovascular diseases
   05418 Fluid shear stress and atherosclerosis
    K04379  FOS; proto-oncogene protein c-fos
  Infectious diseases
   05132 Salmonella infection
    K04379  FOS; proto-oncogene protein c-fos
   05133 Pertussis
    K04379  FOS; proto-oncogene protein c-fos
   05166 HTLV-I infection
    K04379  FOS; proto-oncogene protein c-fos
   05161 Hepatitis B
    K04379  FOS; proto-oncogene protein c-fos
   05168 Herpes simplex infection
    K04379  FOS; proto-oncogene protein c-fos
   05167 Kaposi's sarcoma-associated herpesvirus infection
    K04379  FOS; proto-oncogene protein c-fos
   05140 Leishmaniasis
    K04379  FOS; proto-oncogene protein c-fos
   05142 Chagas disease (American trypanosomiasis)
    K04379  FOS; proto-oncogene protein c-fos
  Drug resistance
   01522 Endocrine resistance
    K04379  FOS; proto-oncogene protein c-fos
Transcription factors [BR:ko03000]
 Eukaryotic Type
  Basic leucine zipper (bZIP)
   AP-1(-like) components, Fos
    K04379  FOS; proto-oncogene protein c-fos
BRITE hierarchy
Genes
HSA: 
2353(FOS)
PTR: 
453047(FOS)
PPS: 
GGO: 
PON: 
NLE: 
MCC: 
702077(FOS)
MCF: 
CSAB: 
RRO: 
RBB: 
CJC: 
SBQ: 
MMU: 
14281(Fos)
RNO: 
314322(Fos)
CGE: 
NGI: 
HGL: 
CCAN: 
OCU: 
TUP: 
CFA: 
490792(FOS)
AML: 
UMR: 
FCA: 
493935(FOS)
PTG: 
AJU: 
BTA: 
280795(FOS)
BOM: 
BIU: 
PHD: 
CHX: 
OAS: 
443218(FOS)
SSC: 
CFR: 
CDK: 
BACU: 
LVE: 
ECB: 
EPZ: 
EAI: 
MYB: 
MYD: 
HAI: 
RSS: 
PALE: 
LAV: 
MDO: 
SHR: 
OAA: 
GGA: 
396512(FOS)
MGP: 
CJO: 
APLA: 
TGU: 
GFR: 
FAB: 
PHI: 
PMAJ: 
CCW: 
FPG: 
CLV: 
AAM: 
ASN: 
AMJ: 
PSS: 
CMY: 
CPIC: 
ACS: 
PVT: 
PBI: 
GJA: 
XLA: 
108698676(fos.L) 447201(fos.S)
XTR: 
548954(fos)
NPR: 
DRE: 
394198(fosab) 564403(si:ch211-153j24.3) 570238(fosaa)
SRX: 
SANH: 
SGH: 
IPU: 
TRU: 
TNG: 
LCO: 
NCC: 
MZE: 
OLA: 
XMA: 
CSEM: 
LCF: 
HCQ: 
BPEC: 
SASA: 
ELS: 
SFM: 
LCM: 
CMK: 
CIN: 
778607(fos)
NAI: 
VG: 
1491891(gag-FOS)
 » show all
TaxonomyVtaxonomyKoalaUniProt
Reference
  Authors
Vesely PW, Staber PB, Hoefler G, Kenner L
  Title
Translational regulation mechanisms of AP-1 proteins.
  Journal
Mutat Res 682:7-12 (2009)
DOI:10.1016/j.mrrev.2009.01.001
Reference
PMID:6574479
  Authors
van Straaten F, Muller R, Curran T, Van Beveren C, Verma IM
  Title
Complete nucleotide sequence of a human c-onc gene: deduced amino acid sequence of the human c-fos protein.
  Journal
Proc Natl Acad Sci U S A 80:3183-7 (1983)
DOI:10.1073/pnas.80.11.3183
  Sequence
[hsa:2353]
Reference
  Authors
Portal MM, Ferrero GO, Caputto BL
  Title
N-Terminal c-Fos tyrosine phosphorylation regulates c-Fos/ER association and c-Fos-dependent phospholipid synthesis activation.
  Journal
Oncogene 26:3551-8 (2007)
DOI:10.1038/sj.onc.1210137
  Sequence
[hsa:2353]

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