KEGG   ORTHOLOGY: K04420Help
Entry
K04420                      KO                                     

Name
MAP3K2, MEKK2
Definition
mitogen-activated protein kinase kinase kinase 2 [EC:2.7.11.25]
Pathway
MAPK signaling pathway
Gap junction
GnRH signaling pathway
Module
M00688  
MAPK (JNK) signaling
M00689  
MAPK (p38) signaling
M00690  
MAPK (ERK5) signaling
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    K04420  MAP3K2, MEKK2; mitogen-activated protein kinase kinase kinase 2
 Cellular Processes
  Cellular community - eukaryotes
   04540 Gap junction
    K04420  MAP3K2, MEKK2; mitogen-activated protein kinase kinase kinase 2
 Organismal Systems
  Endocrine system
   04912 GnRH signaling pathway
    K04420  MAP3K2, MEKK2; mitogen-activated protein kinase kinase kinase 2
KEGG modules [BR:ko00002]
 Functional set
  Cellular processes
   Cell signaling
    M00688  MAPK (JNK) signaling
     K04420  MAP3K2, MEKK2; mitogen-activated protein kinase kinase kinase 2
    M00689  MAPK (p38) signaling
     K04420  MAP3K2, MEKK2; mitogen-activated protein kinase kinase kinase 2
    M00690  MAPK (ERK5) signaling
     K04420  MAP3K2, MEKK2; mitogen-activated protein kinase kinase kinase 2
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.25  mitogen-activated protein kinase kinase kinase
     K04420  MAP3K2, MEKK2; mitogen-activated protein kinase kinase kinase 2
Protein kinases [BR:ko01001]
 Serine/threonine protein kinases: STE group
  STE11 family
   K04420  MAP3K2, MEKK2; mitogen-activated protein kinase kinase kinase 2
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
10746(MAP3K2)
PTR: 
736244(MAP3K2)
PPS: 
100973371(MAP3K2)
GGO: 
101149805(MAP3K2)
PON: 
100450054(MAP3K2)
NLE: 
100601802(MAP3K2)
MCC: 
100424131(MAP3K2)
MCF: 
102138136(MAP3K2)
CSAB: 
103216879(MAP3K2)
RRO: 
104662431(MAP3K2)
RBB: 
108533000(MAP3K2)
CJC: 
100406711(MAP3K2)
SBQ: 
101035799(MAP3K2)
MMU: 
26405(Map3k2)
RNO: 
171492(Map3k2)
CGE: 
100772559(Map3k2)
NGI: 
103732132(Map3k2)
HGL: 
101726195(Map3k2)
CCAN: 
109699113(Map3k2)
OCU: 
100355693(MAP3K2)
TUP: 
102485186(MAP3K2)
CFA: 
612902(MAP3K2)
AML: 
100475426(MAP3K2)
UMR: 
103658571(MAP3K2)
FCA: 
101096406(MAP3K2)
PTG: 
102957925(MAP3K2)
AJU: 
106966378(MAP3K2)
BTA: 
504592(MAP3K2)
BOM: 
102273125(MAP3K2)
BIU: 
109565311(MAP3K2)
PHD: 
102332756(MAP3K2)
CHX: 
102175623(MAP3K2)
OAS: 
101109858(MAP3K2)
SSC: 
100621234(MAP3K2)
CFR: 
102505073(MAP3K2)
CDK: 
105084487(MAP3K2)
BACU: 
103017845(MAP3K2)
LVE: 
103083140(MAP3K2)
ECB: 
100050628(MAP3K2)
EPZ: 
103562194(MAP3K2)
EAI: 
106834092(MAP3K2)
MYB: 
102245865(MAP3K2)
MYD: 
102753581(MAP3K2)
HAI: 
109371823(MAP3K2)
RSS: 
109438242(MAP3K2)
PALE: 
102880422(MAP3K2)
LAV: 
100665139(MAP3K2)
MDO: 
100026735(MAP3K2)
SHR: 
100916713(MAP3K2)
GGA: 
424225(MAP3K2)
MGP: 
100543830(MAP3K2)
CJO: 
107316800(MAP3K2)
APLA: 
101798043(MAP3K2)
ACYG: 
106045922(MAP3K2)
TGU: 
100219827(MAP3K2)
GFR: 
102033648(MAP3K2)
FAB: 
101811653(MAP3K2)
PHI: 
102113050(MAP3K2)
PMAJ: 
107207590(MAP3K2)
CCW: 
104693990(MAP3K2)
FPG: 
101921462(MAP3K2)
FCH: 
102052668(MAP3K2)
CLV: 
102092494(MAP3K2)
AAM: 
106499278(MAP3K2)
ASN: 
AMJ: 
102574412(MAP3K2)
PSS: 
102448094(MAP3K2)
CMY: 
102941356(MAP3K2)
CPIC: 
101934711(MAP3K2)
ACS: 
100558170(map3k2)
PVT: 
110085271(MAP3K2)
PBI: 
103049938(MAP3K2)
GJA: 
107117807(MAP3K2)
XLA: 
108701261(map3k2.L) 108702901(map3k2.S)
XTR: 
100493570(map3k2)
NPR: 
108785393(MAP3K2)
DRE: 
558321(map3k2)
SRX: 
SANH: 
SGH: 
IPU: 
108272715(map3k2)
TRU: 
101069746(map3k2)
TNG: 
LCO: 
104934606(map3k2)
NCC: 
MZE: 
101464541(map3k2)
OLA: 
101160297(map3k2)
XMA: 
102232571(map3k2)
CSEM: 
103389509(map3k2)
LCF: 
HCQ: 
109520183(map3k2)
BPEC: 
SASA: 
ELS: 
105019952(map3k2)
SFM: 
108920647(map3k2)
LCM: 
102350566(MAP3K2)
CMK: 
103189809(map3k2)
BFO: 
CIN: 
SPU: 
SKO: 
BMY: 
HRO: 
LGI: 
CRG: 
OBI: 
LAK: 
NVE: 
ADF: 
TAD: 
AQU: 
CRB: 
CIT: 
CIC: 
GRA: 
GHI: 
RCU: 
NTA: 
EGU: 
MUS: 
MBR: 
PTM: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Craig EA, Stevens MV, Vaillancourt RR, Camenisch TD
  Title
MAP3Ks as central regulators of cell fate during development.
  Journal
Dev Dyn 237:3102-14 (2008)
DOI:10.1002/dvdy.21750

KEGG   ORTHOLOGY: K04421Help
Entry
K04421                      KO                                     

Name
MAP3K3, MEKK3
Definition
mitogen-activated protein kinase kinase kinase 3 [EC:2.7.11.25]
Pathway
MAPK signaling pathway
Neurotrophin signaling pathway
GnRH signaling pathway
HTLV-I infection
Module
M00688  
MAPK (JNK) signaling
M00689  
MAPK (p38) signaling
M00690  
MAPK (ERK5) signaling
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    K04421  MAP3K3, MEKK3; mitogen-activated protein kinase kinase kinase 3
 Organismal Systems
  Endocrine system
   04912 GnRH signaling pathway
    K04421  MAP3K3, MEKK3; mitogen-activated protein kinase kinase kinase 3
  Nervous system
   04722 Neurotrophin signaling pathway
    K04421  MAP3K3, MEKK3; mitogen-activated protein kinase kinase kinase 3
 Human Diseases
  Infectious diseases
   05166 HTLV-I infection
    K04421  MAP3K3, MEKK3; mitogen-activated protein kinase kinase kinase 3
KEGG modules [BR:ko00002]
 Functional set
  Cellular processes
   Cell signaling
    M00688  MAPK (JNK) signaling
     K04421  MAP3K3, MEKK3; mitogen-activated protein kinase kinase kinase 3
    M00689  MAPK (p38) signaling
     K04421  MAP3K3, MEKK3; mitogen-activated protein kinase kinase kinase 3
    M00690  MAPK (ERK5) signaling
     K04421  MAP3K3, MEKK3; mitogen-activated protein kinase kinase kinase 3
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.25  mitogen-activated protein kinase kinase kinase
     K04421  MAP3K3, MEKK3; mitogen-activated protein kinase kinase kinase 3
Protein kinases [BR:ko01001]
 Serine/threonine protein kinases: STE group
  STE11 family
   K04421  MAP3K3, MEKK3; mitogen-activated protein kinase kinase kinase 3
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
4215(MAP3K3)
PTR: 
468286(MAP3K3)
PPS: 
100969705(MAP3K3)
GGO: 
101148044(MAP3K3)
PON: 
100444678(MAP3K3)
NLE: 
100601763(MAP3K3)
MCC: 
717866(MAP3K3)
MCF: 
102132095(MAP3K3)
CSAB: 
103243225(MAP3K3)
RRO: 
104675466(MAP3K3)
RBB: 
108536280(MAP3K3)
CJC: 
100409608(MAP3K3)
SBQ: 
MMU: 
26406(Map3k3)
RNO: 
303604(Map3k3)
CGE: 
100753508(Map3k3)
NGI: 
103744757(Map3k3)
HGL: 
101704335(Map3k3)
CCAN: 
109703189(Map3k3)
OCU: 
100355324(MAP3K3)
TUP: 
102477673(MAP3K3)
CFA: 
480481(MAP3K3)
AML: 
100475740(MAP3K3)
UMR: 
103665628(MAP3K3)
FCA: 
101083633(MAP3K3)
PTG: 
102966576(MAP3K3)
AJU: 
106978686(MAP3K3)
BTA: 
508943(MAP3K3)
BOM: 
102275307(MAP3K3)
BIU: 
109573385(MAP3K3)
PHD: 
102332784(MAP3K3)
CHX: 
102173036(MAP3K3)
OAS: 
101122537(MAP3K3)
SSC: 
100513491(MAP3K3)
CFR: 
102505759(MAP3K3)
CDK: 
105090412(MAP3K3)
BACU: 
102999255(MAP3K3)
LVE: 
103076636(MAP3K3)
ECB: 
100064751(MAP3K3)
EPZ: 
103549765(MAP3K3)
EAI: 
106835525(MAP3K3)
MYB: 
102242308(MAP3K3)
MYD: 
102762787(MAP3K3)
HAI: 
109380266(MAP3K3)
RSS: 
109448040(MAP3K3)
PALE: 
102889570(MAP3K3)
LAV: 
100662122(MAP3K3)
MDO: 
100025970(MAP3K3)
SHR: 
100933837(MAP3K3)
OAA: 
GGA: 
419954(MAP3K3) 420419
MGP: 
CJO: 
APLA: 
ACYG: 
TGU: 
GFR: 
FAB: 
PHI: 
PMAJ: 
CCW: 
FPG: 
FCH: 
CLV: 
AAM: 
ASN: 
AMJ: 
PSS: 
CMY: 
CPIC: 
ACS: 
PVT: 
PBI: 
GJA: 
XLA: 
XTR: 
NPR: 
DRE: 
560211(map3k3)
SRX: 
SANH: 
SGH: 
IPU: 
TRU: 
TNG: 
LCO: 
NCC: 
104943590(map3k3)
MZE: 
OLA: 
XMA: 
CSEM: 
103392663(map3k3)
LCF: 
HCQ: 
BPEC: 
SASA: 
ELS: 
SFM: 
LCM: 
CMK: 
NAI: 
HRO: 
HMG: 
GMX: 
PVU: 
VRA: 
VAR: 
LANG: 
FVE: 
PPER: 
PMUM: 
SPEN: 
INI: 
SRE: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Craig EA, Stevens MV, Vaillancourt RR, Camenisch TD
  Title
MAP3Ks as central regulators of cell fate during development.
  Journal
Dev Dyn 237:3102-14 (2008)
DOI:10.1002/dvdy.21750

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