KEGG   ORTHOLOGY: K04443Help
Entry
K04443                      KO                                     

Name
MAPKAPK2
Definition
mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1]
Pathway
MAPK signaling pathway
Cellular senescence
VEGF signaling pathway
Neurotrophin signaling pathway
Kaposi's sarcoma-associated herpesvirus infection
Viral carcinogenesis
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    K04443  MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2
   04370 VEGF signaling pathway
    K04443  MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2
 Cellular Processes
  Cell growth and death
   04218 Cellular senescence
    K04443  MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2
 Organismal Systems
  Nervous system
   04722 Neurotrophin signaling pathway
    K04443  MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2
 Human Diseases
  Cancers
   05203 Viral carcinogenesis
    K04443  MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2
  Infectious diseases
   05167 Kaposi's sarcoma-associated herpesvirus infection
    K04443  MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     K04443  MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2
Protein kinases [BR:ko01001]
 Serine/threonine protein kinases: CAMK group
  MAPKAPK family [OT]
   K04443  MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2
BRITE hierarchy
Genes
HSA: 
9261(MAPKAPK2)
PTR: 
744091(MAPKAPK2)
PPS: 
100968858(MAPKAPK2)
GGO: 
101151250(MAPKAPK2)
PON: 
100446757(MAPKAPK2)
NLE: 
100579643(MAPKAPK2)
MCC: 
695044(MAPKAPK2)
MCF: 
102131033(MAPKAPK2)
CSAB: 
103230194(MAPKAPK2)
RRO: 
104661739(MAPKAPK2)
RBB: 
108535144(MAPKAPK2)
CJC: 
100393258(MAPKAPK2)
SBQ: 
101052249(MAPKAPK2)
MMU: 
17164(Mapkapk2)
RNO: 
289014(Mapkapk2)
CGE: 
100762218(Mapkapk2)
NGI: 
103725934(Mapkapk2)
HGL: 
101708612(Mapkapk2)
CCAN: 
109688375(Mapkapk2)
OCU: 
100009438(MAPKAPK2)
TUP: 
102483974(MAPKAPK2)
CFA: 
490263(MAPKAPK2)
AML: 
100483931(MAPKAPK2)
UMR: 
103657756(MAPKAPK2)
FCA: 
101090833(MAPKAPK2)
PTG: 
102961644(MAPKAPK2)
AJU: 
106981771(MAPKAPK2)
BTA: 
788091(MAPKAPK2)
BOM: 
102274647(MAPKAPK2)
BIU: 
109570101(MAPKAPK2)
PHD: 
102332267(MAPKAPK2)
CHX: 
102184079(MAPKAPK2)
OAS: 
101118118(MAPKAPK2)
SSC: 
100521986(MAPKAPK2)
CFR: 
102508766(MAPKAPK2)
CDK: 
105098610(MAPKAPK2)
BACU: 
102999332(MAPKAPK2)
LVE: 
103082742(MAPKAPK2)
ECB: 
100055510(MAPKAPK2)
EPZ: 
EAI: 
MYB: 
MYD: 
102775090(MAPKAPK2)
HAI: 
109374513(MAPKAPK2)
RSS: 
109458644(MAPKAPK2)
PALE: 
102887540(MAPKAPK2)
LAV: 
100658205(MAPKAPK2)
MDO: 
100014871(MAPKAPK2)
SHR: 
100917693(MAPKAPK2)
OAA: 
100092220(MAPKAPK2)
GGA: 
419847(MAPKAPK2)
MGP: 
100548519(MAPKAPK2)
CJO: 
107324781(MAPKAPK2)
APLA: 
101789944(MAPKAPK2)
ACYG: 
106041349(MAPKAPK2)
GFR: 
102044089(MAPKAPK2)
PHI: 
102106065(MAPKAPK2)
PMAJ: 
107214766(MAPKAPK2)
CCW: 
104692513(MAPKAPK2)
FPG: 
101911197(MAPKAPK2)
FCH: 
102050830(MAPKAPK2)
CLV: 
102085947(MAPKAPK2)
AAM: 
106495796(MAPKAPK2)
ASN: 
102383452(MAPKAPK2)
AMJ: 
102563674(MAPKAPK2)
PSS: 
102445709(MAPKAPK2)
CMY: 
102948283(MAPKAPK2)
CPIC: 
101936401(MAPKAPK2)
ACS: 
100562891(mapkapk2)
PVT: 
110088404(MAPKAPK2)
PBI: 
103050162(MAPKAPK2)
GJA: 
107124264(MAPKAPK2)
XLA: 
432084(mapkapk2.L) 495118
XTR: 
550101(mapkapk2)
NPR: 
108793180(MAPKAPK2)
DRE: 
327321(mapkapk2a)
SRX: 
SANH: 
SGH: 
IPU: 
108255116(mapkapk2)
AMEX: 
TRU: 
101074595(mapkapk2)
TNG: 
LCO: 
NCC: 
MZE: 
101471444(mapkapk2)
OLA: 
101157364(mapkapk2)
XMA: 
102228209(mapkapk2)
CSEM: 
103386073(mapkapk2)
LCF: 
HCQ: 
BPEC: 
SASA: 
ELS: 
105013205(mapkapk2)
SFM: 
LCM: 
102362783(MAPKAPK2)
CMK: 
103182495(mapkapk2)
BFO: 
SPU: 
APLC: 
DME: 
Dmel_CG3086(MAPk-Ak2)
DPO: 
DAN: 
DER: 
DPE: 
DSI: 
Dsimw501_GD16235(Dsim_GD16235)
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
MDE: 
AGA: 
AAG: 
CQU: 
BIM: 
BTER: 
SOC: 
AEC: 
ACEP: 
PBAR: 
HST: 
CFO: 
LHU: 
PGC: 
NVI: 
TCA: 
DPA: 
NVL: 
BMOR: 
DPL: 
PXY: 
API: 
DNX: 
PHU: 
FCD: 
DPX: 
ISC: 
TUT: 
CBR: 
CBG13977(Cbr-mak-2)
NAI: 
BMY: 
LOA: 
HRO: 
LGI: 
CRG: 
LAK: 
SMM: 
SHX: 
OVI: 
NVE: 
ADF: 
HMG: 
TAD: 
AQU: 
PTM: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Cargnello M, Roux PP
  Title
Activation and function of the MAPKs and their substrates, the MAPK-activated protein kinases.
  Journal
Microbiol Mol Biol Rev 75:50-83 (2011)
DOI:10.1128/MMBR.00031-10
Reference
PMID:8179591
  Authors
Zu YL, Wu F, Gilchrist A, Ai Y, Labadia ME, Huang CK
  Title
The primary structure of a human MAP kinase activated protein kinase 2.
  Journal
Biochem Biophys Res Commun 200:1118-24 (1994)
DOI:10.1006/bbrc.1994.1566
  Sequence
[hsa:9261]

KEGG   ORTHOLOGY: K04444Help
Entry
K04444                      KO                                     

Name
MAPKAPK3
Definition
mitogen-activated protein kinase-activated protein kinase 3 [EC:2.7.11.1]
Pathway
MAPK signaling pathway
VEGF signaling pathway
Disease
H01890  
Pattern dystrophies of the retinal pigment epithelium
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    K04444  MAPKAPK3; mitogen-activated protein kinase-activated protein kinase 3
   04370 VEGF signaling pathway
    K04444  MAPKAPK3; mitogen-activated protein kinase-activated protein kinase 3
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     K04444  MAPKAPK3; mitogen-activated protein kinase-activated protein kinase 3
Protein kinases [BR:ko01001]
 Serine/threonine protein kinases: CAMK group
  MAPKAPK family [OT]
   K04444  MAPKAPK3; mitogen-activated protein kinase-activated protein kinase 3
BRITE hierarchy
Genes
HSA: 
7867(MAPKAPK3)
PTR: 
460400(MAPKAPK3)
PPS: 
100968829(MAPKAPK3)
GGO: 
101131430(MAPKAPK3)
PON: 
100449366(MAPKAPK3)
NLE: 
100597822(MAPKAPK3)
MCC: 
701320(MAPKAPK3)
MCF: 
102120448(MAPKAPK3)
CSAB: 
RRO: 
104666815(MAPKAPK3)
RBB: 
108526941(MAPKAPK3)
CJC: 
100410636(MAPKAPK3)
SBQ: 
101035301(MAPKAPK3)
MMU: 
102626(Mapkapk3)
RNO: 
315994(Mapkapk3)
CGE: 
100774379(Mapkapk3)
NGI: 
103750143(Mapkapk3)
HGL: 
101717099(Mapkapk3)
CCAN: 
109693236(Mapkapk3)
OCU: 
100342292(MAPKAPK3)
TUP: 
102493562(MAPKAPK3)
CFA: 
484756(MAPKAPK3)
AML: 
100484361(MAPKAPK3)
UMR: 
103674786(MAPKAPK3)
FCA: 
101096794(MAPKAPK3)
PTG: 
102970828(MAPKAPK3)
AJU: 
106979271(MAPKAPK3)
BTA: 
615215(MAPKAPK3)
BOM: 
102283364(MAPKAPK3)
BIU: 
109576279(MAPKAPK3)
PHD: 
102342118(MAPKAPK3)
CHX: 
102175629(MAPKAPK3)
OAS: 
101118996(MAPKAPK3)
SSC: 
100233192(MAPKAPK3)
CFR: 
102518308(MAPKAPK3)
CDK: 
105087288(MAPKAPK3)
BACU: 
103001513(MAPKAPK3)
LVE: 
103077980(MAPKAPK3)
ECB: 
100061475(MAPKAPK3)
EPZ: 
103559274(MAPKAPK3)
EAI: 
106830742(MAPKAPK3)
MYB: 
102241413(MAPKAPK3)
MYD: 
102757924(MAPKAPK3)
HAI: 
109378052(MAPKAPK3)
RSS: 
109443425(MAPKAPK3)
PALE: 
102882134(MAPKAPK3)
LAV: 
100666073(MAPKAPK3)
MDO: 
100028919(MAPKAPK3)
SHR: 
100918613(MAPKAPK3)
OAA: 
100075476(MAPKAPK3)
GGA: 
415917(MAPKAPK3)
MGP: 
100544877(MAPKAPK3)
CJO: 
107319569(MAPKAPK3)
APLA: 
101801666(MAPKAPK3)
ACYG: 
106042816(MAPKAPK3)
TGU: 
100225000(MAPKAPK3)
GFR: 
102043737(MAPKAPK3)
FAB: 
101806698(MAPKAPK3)
PHI: 
102114178(MAPKAPK3)
PMAJ: 
107210185(MAPKAPK3)
CCW: 
104683208(MAPKAPK3)
FPG: 
101919073(MAPKAPK3)
FCH: 
102047898(MAPKAPK3)
CLV: 
102094261(MAPKAPK3)
AAM: 
106492166(MAPKAPK3)
ASN: 
102380990(MAPKAPK3)
AMJ: 
106736633(MAPKAPK3)
PSS: 
102463404(MAPKAPK3)
CMY: 
102940828(MAPKAPK3)
CPIC: 
101934644(MAPKAPK3)
ACS: 
100565363(mapkapk3)
PVT: 
110076526(MAPKAPK3)
PBI: 
103057187(MAPKAPK3)
GJA: 
107123857(MAPKAPK3)
XLA: 
108714604 779225(mapkapk3.S)
XTR: 
780323(mapkapk3)
NPR: 
DRE: 
790934(mapkapk3)
SRX: 
SANH: 
SGH: 
IPU: 
AMEX: 
103038695(mapkapk3)
TRU: 
TNG: 
LCO: 
NCC: 
MZE: 
OLA: 
XMA: 
CSEM: 
LCF: 
HCQ: 
BPEC: 
SASA: 
ELS: 
SFM: 
LCM: 
102347953(MAPKAPK3)
CMK: 
103176715(mapkapk3)
CIN: 
TSP: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Cargnello M, Roux PP
  Title
Activation and function of the MAPKs and their substrates, the MAPK-activated protein kinases.
  Journal
Microbiol Mol Biol Rev 75:50-83 (2011)
DOI:10.1128/MMBR.00031-10

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