KEGG   ORTHOLOGY: K04445Help
Entry
K04445                      KO                                     

Name
RPS6KA5, MSK1
Definition
ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
Pathway
ko04010  MAPK signaling pathway
ko04261  Adrenergic signaling in cardiomyocytes
ko04668  TNF signaling pathway
ko04713  Circadian entrainment
ko04722  Neurotrophin signaling pathway
ko05200  Pathways in cancer
ko05206  MicroRNAs in cancer
ko05219  Bladder cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    K04445  RPS6KA5, MSK1; ribosomal protein S6 kinase alpha-5
   04668 TNF signaling pathway
    K04445  RPS6KA5, MSK1; ribosomal protein S6 kinase alpha-5
 Organismal Systems
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    K04445  RPS6KA5, MSK1; ribosomal protein S6 kinase alpha-5
  Nervous system
   04722 Neurotrophin signaling pathway
    K04445  RPS6KA5, MSK1; ribosomal protein S6 kinase alpha-5
  Environmental adaptation
   04713 Circadian entrainment
    K04445  RPS6KA5, MSK1; ribosomal protein S6 kinase alpha-5
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K04445  RPS6KA5, MSK1; ribosomal protein S6 kinase alpha-5
   05206 MicroRNAs in cancer
    K04445  RPS6KA5, MSK1; ribosomal protein S6 kinase alpha-5
   05219 Bladder cancer
    K04445  RPS6KA5, MSK1; ribosomal protein S6 kinase alpha-5
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     K04445  RPS6KA5, MSK1; ribosomal protein S6 kinase alpha-5
Protein kinases [BR:ko01001]
 Serine/threonine kinases: AGC group
  RSK family [OT]
   K04445  RPS6KA5, MSK1; ribosomal protein S6 kinase alpha-5
BRITE hierarchy
Other DBs
GO: 0004711
Genes
HSA: 9252(RPS6KA5)
PTR: 739162(RPS6KA5)
PPS: 100971222(RPS6KA5)
GGO: 101152851(RPS6KA5)
PON: 100173967(RPS6KA5)
NLE: 100597734(RPS6KA5)
MCC: 699798(RPS6KA5)
MCF: 102137672(RPS6KA5)
CSAB: 103229550(RPS6KA5)
RRO: 104670551(RPS6KA5)
RBB: 108523306 108535909(RPS6KA5)
CJC: 100411926(RPS6KA5)
SBQ: 101047847(RPS6KA5)
MMU: 73086(Rps6ka5)
RNO: 314384(Rps6ka5)
CGE: 100753249(Rps6ka5)
NGI: 103724612(Rps6ka5)
HGL: 101712306(Rps6ka5)
OCU: 100348520(RPS6KA5)
TUP: 102486242(RPS6KA5)
CFA: 490831(RPS6KA5)
AML: 100482684(RPS6KA5)
UMR: 103673837(RPS6KA5)
ORO: 101380272(RPS6KA5)
FCA: 101095179(RPS6KA5)
PTG: 102952316(RPS6KA5)
AJU: 106987903(RPS6KA5)
BTA: 504408(RPS6KA5)
BOM: 102283727(RPS6KA5)
BIU: 109565420(RPS6KA5)
PHD: 102329968(RPS6KA5)
CHX: 102191054(RPS6KA5)
OAS: 101115714(RPS6KA5)
CFR: 102512204(RPS6KA5)
CDK: 105095956(RPS6KA5)
BACU: 102999918(RPS6KA5)
LVE: 103080020(RPS6KA5)
OOR: 101286651(RPS6KA5)
ECB: 100062953(RPS6KA5)
EPZ: 103558014(RPS6KA5)
EAI: 106825387(RPS6KA5)
MYB: 102252210(RPS6KA5)
MYD: 102754112(RPS6KA5)
HAI: 109382677(RPS6KA5)
RSS: 109454403(RPS6KA5)
PALE: 102897813(RPS6KA5)
LAV: 100664075(RPS6KA5)
TMU: 101358750
MDO: 100017874(RPS6KA5) 100031342(RPS6KA4)
SHR: 100931885(RPS6KA5)
OAA: 100075221(RPS6KA5)
GGA: 423408(RPS6KA5)
MGP: 100539762(RPS6KA5)
CJO: 107315199(RPS6KA5)
APLA: 101790699(RPS6KA5)
ACYG: 106033496(RPS6KA5)
TGU: 100219984(RPS6KA5)
GFR: 102033196(RPS6KA5)
FAB: 101818385(RPS6KA5)
PHI: 102108626(RPS6KA5)
PMAJ: 107205560(RPS6KA5)
CCW: 104688674(RPS6KA5)
FPG: 101919264(RPS6KA5)
FCH: 102049415(RPS6KA5)
CLV: 102089255(RPS6KA5)
EGZ: 104135349(RPS6KA5)
AAM: 106482922(RPS6KA5)
ASN: 102381351(RPS6KA5)
AMJ: 102576860(RPS6KA5)
PSS: 102463390(RPS6KA5)
CMY: 102931440(RPS6KA5)
CPIC: 101938686(RPS6KA5)
ACS: 100562399(rps6ka5)
PVT: 110086584(RPS6KA5)
PBI: 103055719(RPS6KA5)
GJA: 107113343(RPS6KA5)
XLA: 108698712(rps6ka5.L)
XTR: 100489041(rps6ka5)
NPR: 108788677(RPS6KA5)
DRE: 565173(rps6ka5)
IPU: 108270373
AMEX: 103042710(rps6ka5)
TRU: 101078142(rps6ka5)
LCO: 104929996(rps6ka5)
NCC: 104942073
MZE: 101468435(rps6ka5)
PRET: 103458380(rps6ka5)
NFU: 107392009
CSEM: 103380459
LCF: 108875022
HCQ: 109528183
BPEC: 110156325(rps6ka5)
ELS: 105026862
SFM: 108922615(rps6ka5) 108924108
LCM: 102345787(RPS6KA4) 102352936(RPS6KA5)
CMK: 103177970 103189665(rps6ka5)
CIN: 100175922(rps6ka5)
SPU: 581399
APLC: 110989928
DME: Dmel_CG6297(JIL-1)
DSI: Dsimw501_GD12830(Dsim_GD12830)
MDE: 101901720
AAG: 5574425
AME: 411630(JIL-1)
BIM: 100742551
BTER: 100647851
SOC: 105195059
AEC: 105146926
ACEP: 105623695
PBAR: 105429561
HST: 105189950
CFO: 105256569
LHU: 105676097
PGC: 109857516
NVI: 100122294
TCA: 658616
DPA: 109546463
NVL: 108558195
BMOR: 101741339
PMAC: 106708114
TUT: 107360633
CEL: CELE_C54G4.1(rskn-2)
CBR: CBG08209(Cbr-rskn-2)
BMY: Bm1_26815
CRG: 105332128
MYI: 110463437
OBI: 106869891
EPA: 110243840
ADF: 107342608
HMG: 100213368
AQU: 100639543
MCHA: 111020053
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Soloaga A, Thomson S, Wiggin GR, Rampersaud N, Dyson MH, Hazzalin CA, Mahadevan LC, Arthur JS
  Title
MSK2 and MSK1 mediate the mitogen- and stress-induced phosphorylation of histone H3 and HMG-14.
  Journal
EMBO J 22:2788-97 (2003)
DOI:10.1093/emboj/cdg273

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