KEGG   ORTHOLOGY: K04454Help
Entry
K04454                      KO                                     

Name
MEF2C
Definition
MADS-box transcription enhancer factor 2C
Pathway
MAPK signaling pathway
cGMP-PKG signaling pathway
Apelin signaling pathway
Oxytocin signaling pathway
Parathyroid hormone synthesis, secretion and action
Transcriptional misregulation in cancer
Fluid shear stress and atherosclerosis
Disease
H00773  
Autosomal dominant mental retardation
H01223  
Mental retardation-stereotypic movements-epilepsy and/or cerebral malformations (MRSME)
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    K04454  MEF2C; MADS-box transcription enhancer factor 2C
   04371 Apelin signaling pathway
    K04454  MEF2C; MADS-box transcription enhancer factor 2C
   04022 cGMP - PKG signaling pathway
    K04454  MEF2C; MADS-box transcription enhancer factor 2C
 Organismal Systems
  Endocrine system
   04921 Oxytocin signaling pathway
    K04454  MEF2C; MADS-box transcription enhancer factor 2C
   04928 Parathyroid hormone synthesis, secretion and action
    K04454  MEF2C; MADS-box transcription enhancer factor 2C
 Human Diseases
  Cancers
   05202 Transcriptional misregulation in cancers
    K04454  MEF2C; MADS-box transcription enhancer factor 2C
  Cardiovascular diseases
   05418 Fluid shear stress and atherosclerosis
    K04454  MEF2C; MADS-box transcription enhancer factor 2C
Transcription factors [BR:ko03000]
 Eukaryotic Type
  beta-Scaffold factors with minor groove contacts
   MADS-box regulators of differentiation, MEF-2
    K04454  MEF2C; MADS-box transcription enhancer factor 2C
BRITE hierarchy
Genes
HSA: 
4208(MEF2C)
PTR: 
461760(MEF2C)
PPS: 
100975251(MEF2C)
GGO: 
101139415(MEF2C)
PON: 
100174751(MEF2C)
NLE: 
100585129(MEF2C)
MCC: 
694992(MEF2C)
MCF: 
102135088(MEF2C)
CSAB: 
103224375(MEF2C)
RRO: 
104657758(MEF2C)
RBB: 
108541059(MEF2C)
CJC: 
100413265(MEF2C)
SBQ: 
101029713(MEF2C)
MMU: 
17260(Mef2c)
RNO: 
499497(Mef2c)
CGE: 
100774573(Mef2c)
NGI: 
103739124(Mef2c)
HGL: 
101716335(Mef2c)
CCAN: 
109695254(Mef2c)
OCU: 
100345167(MEF2C)
TUP: 
102499043(MEF2C)
CFA: 
479155(MEF2C)
AML: 
100464632(MEF2C)
UMR: 
103672150(MEF2C)
ORO: 
101370419(MEF2C)
FCA: 
101096136(MEF2C)
PTG: 
102962519(MEF2C)
AJU: 
106968666(MEF2C)
BTA: 
512254(MEF2C)
BOM: 
102286323(MEF2C)
BIU: 
109562320(MEF2C)
PHD: 
102315309(MEF2C)
CHX: 
102175290(MEF2C)
OAS: 
100286738(MEF2C)
SSC: 
733590(MEF2C)
CFR: 
102507710(MEF2C)
CDK: 
105099639(MEF2C)
BACU: 
103010647(MEF2C)
LVE: 
103077870(MEF2C)
OOR: 
101273160(MEF2C)
ECB: 
100065153(MEF2C)
EPZ: 
103550208(MEF2C)
EAI: 
106841211(MEF2C)
MYB: 
102248648(MEF2C)
MYD: 
102763270(MEF2C)
HAI: 
109381982(MEF2C)
RSS: 
109448659(MEF2C)
PALE: 
102883825(MEF2C)
LAV: 
100656767(MEF2C)
TMU: 
MDO: 
100013140(MEF2C)
SHR: 
100932067(MEF2C)
OAA: 
100079500(MEF2C)
GGA: 
769007(MEF2C)
MGP: 
100549600(MEF2C)
CJO: 
107306494(MEF2C)
APLA: 
101789482(MEF2C)
ACYG: 
106047563(MEF2C)
TGU: 
100218659(MEF2C)
GFR: 
102041745(MEF2C)
FAB: 
101809833(MEF2C)
PHI: 
102108298(MEF2C)
PMAJ: 
107216154(MEF2C)
CCW: 
104685221(MEF2C)
FPG: 
101912452(MEF2C)
FCH: 
102050180(MEF2C)
CLV: 
102090045(MEF2C)
EGZ: 
104128384(MEF2C)
AAM: 
ASN: 
102379600(MEF2C)
AMJ: 
102573957(MEF2C)
PSS: 
102460770(MEF2C)
CMY: 
102944657(MEF2C)
CPIC: 
101945993(MEF2C)
ACS: 
100559834(mef2c)
PVT: 
110073989(MEF2C)
PBI: 
103056615(MEF2C)
GJA: 
107116735(MEF2C)
XLA: 
108707236(mef2c.S) 444310(mef2c.L)
XTR: 
100127198(mef2c)
NPR: 
108789272(MEF2C)
DRE: 
30575(mef2ca) 798771(mef2cb)
SRX: 
SANH: 
SGH: 
CCAR: 
IPU: 
108255865(mef2c)
AMEX: 
TRU: 
TNG: 
LCO: 
NCC: 
MZE: 
OLA: 
XMA: 
PRET: 
NFU: 
CSEM: 
LCF: 
108878284(mef2c)
HCQ: 
BPEC: 
SASA: 
ELS: 
SFM: 
LCM: 
102361694(MEF2C)
CMK: 
CIN: 
778677(mef2)
CRG: 
OBI: 
CSAT: 
EUS: 
BRP: 
BNA: 
BOE: 
THJ: 
CPAP: 
CIC: 
TCC: 
GRA: 
GHI: 
DZI: 
GMX: 
PVU: 
CCAJ: 
MTR: 
CAM: 
AIP: 
PAVI: 
CMO: 
CMAX: 
RCU: 
JCU: 
JRE: 
VVI: 
SLY: 
SOT: 
NTO: 
SIND: 
HAN: 
SOE: 
NNU: 
DCT: 
MNG: 
ACAN: 
 » show all
TaxonomyKoalaUniProt
Reference
PMID:7679508
  Authors
Leifer D, Krainc D, Yu YT, McDermott J, Breitbart RE, Heng J, Neve RL, Kosofsky B, Nadal-Ginard B, Lipton SA
  Title
MEF2C, a MADS/MEF2-family transcription factor expressed in a laminar distribution in cerebral cortex.
  Journal
Proc Natl Acad Sci U S A 90:1546-50 (1993)
DOI:10.1073/pnas.90.4.1546
  Sequence
[hsa:4208]

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