KEGG   ORTHOLOGY: K04463Help
Entry
K04463                      KO                                     

Name
MAP2K5, MEK5
Definition
mitogen-activated protein kinase kinase 5 [EC:2.7.12.2]
Pathway
ko04010  MAPK signaling pathway
ko04540  Gap junction
ko04722  Neurotrophin signaling pathway
ko04921  Oxytocin signaling pathway
ko05418  Fluid shear stress and atherosclerosis
Module
M00690  MAPK (ERK5) signaling
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    K04463  MAP2K5, MEK5; mitogen-activated protein kinase kinase 5
 Cellular Processes
  Cellular community - eukaryotes
   04540 Gap junction
    K04463  MAP2K5, MEK5; mitogen-activated protein kinase kinase 5
 Organismal Systems
  Endocrine system
   04921 Oxytocin signaling pathway
    K04463  MAP2K5, MEK5; mitogen-activated protein kinase kinase 5
  Nervous system
   04722 Neurotrophin signaling pathway
    K04463  MAP2K5, MEK5; mitogen-activated protein kinase kinase 5
 Human Diseases
  Cardiovascular diseases
   05418 Fluid shear stress and atherosclerosis
    K04463  MAP2K5, MEK5; mitogen-activated protein kinase kinase 5
KEGG modules [BR:ko00002]
 Functional set
  Cellular processes
   Cell signaling
    M00690  MAPK (ERK5) signaling
     K04463  MAP2K5, MEK5; mitogen-activated protein kinase kinase 5
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     K04463  MAP2K5, MEK5; mitogen-activated protein kinase kinase 5
Protein kinases [BR:ko01001]
 Serine/threonine kinases: STE group
  STE7 family
   K04463  MAP2K5, MEK5; mitogen-activated protein kinase kinase 5
BRITE hierarchy
Other DBs
GO: 0004708
Genes
HSA: 5607(MAP2K5)
PTR: 453532(MAP2K5)
PPS: 100994910(MAP2K5)
GGO: 101137194(MAP2K5)
PON: 100449213(MAP2K5)
NLE: 100589848(MAP2K5)
MCC: 711672(MAP2K5)
MCF: 102118759(MAP2K5)
CSAB: 103245427(MAP2K5)
RRO: 104662585(MAP2K5)
RBB: 108514696(MAP2K5)
CJC: 100395249(MAP2K5)
SBQ: 101037814(MAP2K5)
MMU: 23938(Map2k5)
RNO: 29568(Map2k5)
CGE: 100760095(Map2k5)
NGI: 103736811(Map2k5)
HGL: 101711080(Map2k5)
CCAN: 109685304(Map2k5)
OCU: 100358715(MAP2K5)
TUP: 102469877(MAP2K5)
CFA: 609559(MAP2K5)
AML: 100468286(MAP2K5)
UMR: 103679052(MAP2K5)
ORO: 101383722(MAP2K5)
FCA: 101100725(MAP2K5)
PTG: 102949008(MAP2K5)
AJU: 106980398(MAP2K5)
BTA: 100295732(MAP2K5)
BOM: 102283668(MAP2K5)
BIU: 109564709(MAP2K5)
PHD: 102331780(MAP2K5)
CHX: 102170427(MAP2K5)
OAS: 101104069(MAP2K5)
SSC: 106504229(MAP2K5)
CFR: 102517293(MAP2K5)
CDK: 105093278(MAP2K5)
BACU: 103019868(MAP2K5)
LVE: 103073248 103088140(MAP2K5)
OOR: 101289255(MAP2K5)
ECB: 100052849(MAP2K5)
EPZ: 103561410(MAP2K5)
EAI: 106840611(MAP2K5)
MYB: 102260280(MAP2K5)
MYD: 102756005(MAP2K5)
HAI: 109385248(MAP2K5)
RSS: 109444318(MAP2K5)
PALE: 102894177(MAP2K5)
LAV: 100669040(MAP2K5)
TMU: 101345785
MDO: 100025486(MAP2K5)
SHR: 100924259(MAP2K5)
OAA: 100085895(MAP2K5)
GGA: 415557(MAP2K5)
MGP: 100544509(MAP2K5)
CJO: 107318914(MAP2K5)
APLA: 101801808(MAP2K5)
ACYG: 106043660(MAP2K5)
TGU: 100219724(MAP2K5)
GFR: 102032727(MAP2K5)
FAB: 101815546(MAP2K5)
PHI: 102106364(MAP2K5)
PMAJ: 107209134(MAP2K5)
CCW: 104683873(MAP2K5)
FPG: 101924559(MAP2K5)
FCH: 102053857(MAP2K5)
CLV: 102095101(MAP2K5)
EGZ: 104125237(MAP2K5)
AAM: 106494573(MAP2K5)
ASN: 102380357(MAP2K5)
AMJ: 102574038(MAP2K5)
PSS: 102451373(MAP2K5)
CMY: 102946856(MAP2K5)
CPIC: 101948796(MAP2K5)
ACS: 100562970(map2k5)
PVT: 110087994(MAP2K5)
PBI: 103059198(MAP2K5)
GJA: 107113289(MAP2K5)
XLA: 414694(map2k5.L)
XTR: 549042(map2k5)
NPR: 108784075(MAP2K5)
DRE: 100007679(map2k5)
SRX: 107755097
IPU: 108259579(map2k5)
AMEX: 103027486(map2k5)
TRU: 101078396(map2k5)
LCO: 104927745(map2k5)
NCC: 104949852(map2k5)
MZE: 101486139(map2k5)
OLA: 101169919(map2k5)
XMA: 102235643(map2k5)
PRET: 103462105(map2k5)
NFU: 107381740(map2k5)
CSEM: 103379107(map2k5)
LCF: 108887875(map2k5)
HCQ: 109514411(map2k5)
BPEC: 110174525(map2k5)
ELS: 105013604(map2k5)
SFM: 108934673(map2k5)
LCM: 102357895(MAP2K5)
CMK: 103189582(map2k5)
CIN: 778673(mapkk5)
SPU: 581169
APLC: 110988174
SKO: 100366587
CRG: 105344402
MYI: 110455995
OBI: 106870780
ADF: 107332317
HMG: 100203621
 » show all
TaxonomyKoalaUniProt
Reference
PMID:7759517
  Authors
Zhou G, Bao ZQ, Dixon JE
  Title
Components of a new human protein kinase signal transduction pathway.
  Journal
J Biol Chem 270:12665-9 (1995)
DOI:10.1074/jbc.270.21.12665
  Sequence
[hsa:5607]

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