KEGG   ORTHOLOGY: K04694Help
Entry
K04694                      KO                                     

Name
SOCS1, JAB
Definition
suppressor of cytokine signaling 1
Pathway
Ubiquitin mediated proteolysis
Osteoclast differentiation
Jak-STAT signaling pathway
Insulin signaling pathway
Prolactin signaling pathway
Type II diabetes mellitus
Toxoplasmosis
MicroRNAs in cancer
Module
M00388  
ECS complex
M00684  
JAK-STAT signaling
Brite
KEGG Orthology (KO) [BR:ko00001]
 Genetic Information Processing
  Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    K04694  SOCS1, JAB; suppressor of cytokine signaling 1
 Environmental Information Processing
  Signal transduction
   04630 Jak-STAT signaling pathway
    K04694  SOCS1, JAB; suppressor of cytokine signaling 1
 Organismal Systems
  Endocrine system
   04910 Insulin signaling pathway
    K04694  SOCS1, JAB; suppressor of cytokine signaling 1
   04917 Prolactin signaling pathway
    K04694  SOCS1, JAB; suppressor of cytokine signaling 1
  Development
   04380 Osteoclast differentiation
    K04694  SOCS1, JAB; suppressor of cytokine signaling 1
 Human Diseases
  Cancers
   05206 MicroRNAs in cancer
    K04694  SOCS1, JAB; suppressor of cytokine signaling 1
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    K04694  SOCS1, JAB; suppressor of cytokine signaling 1
  Infectious diseases
   05145 Toxoplasmosis
    K04694  SOCS1, JAB; suppressor of cytokine signaling 1
KEGG modules [BR:ko00002]
 Structural complex
  Genetic information processing
   Ubiquitin system
    M00388  ECS complex
     K04694  SOCS1, JAB; suppressor of cytokine signaling 1
 Functional set
  Cellular processes
   Cell signaling
    M00684  JAK-STAT signaling
     K04694  SOCS1, JAB; suppressor of cytokine signaling 1
Ubiquitin system [BR:ko04121]
 Ubiquitin ligases (E3)
  Multi subunit Ring-finger type E3
   ECS complex
    Target recognizing subunit (SOCS box)
     K04694  SOCS1, JAB; suppressor of cytokine signaling 1
BRITE hierarchy
Genes
HSA: 
8651(SOCS1)
PTR: 
737070(SOCS1)
GGO: 
101131805(SOCS1)
PON: 
100445635(SOCS1)
NLE: 
100589181(SOCS1)
MCC: 
711180(SOCS1)
MCF: 
102135411(SOCS1)
CSAB: 
103228298(SOCS1)
RRO: 
104667710(SOCS1)
RBB: 
108541230(SOCS1)
CJC: 
100402275(SOCS1)
SBQ: 
101050866(SOCS1)
MMU: 
12703(Socs1)
RNO: 
252971(Socs1)
CGE: 
100751218(Socs1)
NGI: 
103731577(Socs1)
HGL: 
101723330(Socs1)
CCAN: 
109676553(Socs1)
OCU: 
100339386(SOCS1)
TUP: 
102495553(SOCS1)
CFA: 
490006(SOCS1)
AML: 
100480183(SOCS1)
BTA: 
518795(SOCS1)
BIU: 
109578851(SOCS1)
CHX: 
106503587(SOCS1)
OAS: 
101107324(SOCS1)
SSC: 
100307052(SOCS1)
CDK: 
105089066(SOCS1)
BACU: 
103000775(SOCS1)
LVE: 
103089381(SOCS1)
ECB: 
102148488(SOCS1)
EAI: 
106836751(SOCS1)
MYB: 
102248245(SOCS1)
MYD: 
102772456(SOCS1)
HAI: 
109387185(SOCS1)
RSS: 
109435893(SOCS1)
PALE: 
102878735(SOCS1)
LAV: 
100664110(SOCS1)
MDO: 
100025389(SOCS1)
SHR: 
100917658(SOCS1)
GGA: 
416630(SOCS1)
MGP: 
100546769(SOCS1)
CJO: 
107320828(SOCS1)
APLA: 
101801940(SOCS1)
ACYG: 
106041226(SOCS1)
TGU: 
100228306(SOCS1)
GFR: 
102041615(SOCS1)
FAB: 
101818258(SOCS1)
PHI: 
102099147(SOCS1)
PMAJ: 
107211147(SOCS1)
CCW: 
104684708(SOCS1)
FPG: 
101912887(SOCS1)
FCH: 
102054761(SOCS1)
CLV: 
102092369(SOCS1)
AAM: 
106482609(SOCS1)
ASN: 
102376072(SOCS1)
AMJ: 
102562879(SOCS1)
PSS: 
102443510(SOCS1)
CMY: 
102932360(SOCS1)
CPIC: 
ACS: 
100560891(socs1)
PVT: 
110087059(SOCS1)
PBI: 
103067787(SOCS1)
GJA: 
107109323(SOCS1)
XLA: 
100294520(socs1.L) 108715012 443921(socs1.S)
XTR: 
496789(socs1)
NPR: 
108798879(SOCS1)
DRE: 
445073(socs1a)
SRX: 
SANH: 
SGH: 
IPU: 
TRU: 
TNG: 
LCO: 
NCC: 
MZE: 
OLA: 
XMA: 
CSEM: 
LCF: 
HCQ: 
BPEC: 
110155763(socs1)
SASA: 
ELS: 
SFM: 
LCM: 
CMK: 
VG: 
935405(Isaknvgp103)
 » show all
TaxonomyVtaxonomyKoalaUniProt
Reference
  Authors
Kile BT, Schulman BA, Alexander WS, Nicola NA, Martin HM, Hilton DJ.
  Title
The SOCS box: a tale of destruction and degradation.
  Journal
Trends Biochem Sci 27:235-41 (2002)
DOI:10.1016/S0968-0004(02)02085-6
  Sequence
[hsa:8651]
Reference
  Authors
Rui L, Yuan M, Frantz D, Shoelson S, White MF.
  Title
SOCS-1 and SOCS-3 block insulin signaling by ubiquitin-mediated degradation of IRS1 and IRS2.
  Journal
J Biol Chem 277:42394-8 (2002)
DOI:10.1074/jbc.C200444200
  Sequence
[hsa:8651] [mmu:12703]
Reference
  Authors
Kamizono S, Hanada T, Yasukawa H, Minoguchi S, Kato R, Minoguchi M, Hattori K, Hatakeyama S, Yada M, Morita S, Kitamura T, Kato H, Nakayama Ki, Yoshimura A
  Title
The SOCS box of SOCS-1 accelerates ubiquitin-dependent proteolysis of TEL-JAK2.
  Journal
J Biol Chem 276:12530-8 (2001)
DOI:10.1074/jbc.M010074200
  Sequence
[hsa:8651]

KEGG   ORTHOLOGY: K04695Help
Entry
K04695                      KO                                     

Name
SOCS2, CIS2
Definition
suppressor of cytokine signaling 2
Pathway
Jak-STAT signaling pathway
Insulin signaling pathway
Prolactin signaling pathway
Type II diabetes mellitus
Module
M00388  
ECS complex
M00684  
JAK-STAT signaling
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04630 Jak-STAT signaling pathway
    K04695  SOCS2, CIS2; suppressor of cytokine signaling 2
 Organismal Systems
  Endocrine system
   04910 Insulin signaling pathway
    K04695  SOCS2, CIS2; suppressor of cytokine signaling 2
   04917 Prolactin signaling pathway
    K04695  SOCS2, CIS2; suppressor of cytokine signaling 2
 Human Diseases
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    K04695  SOCS2, CIS2; suppressor of cytokine signaling 2
KEGG modules [BR:ko00002]
 Structural complex
  Genetic information processing
   Ubiquitin system
    M00388  ECS complex
     K04695  SOCS2, CIS2; suppressor of cytokine signaling 2
 Functional set
  Cellular processes
   Cell signaling
    M00684  JAK-STAT signaling
     K04695  SOCS2, CIS2; suppressor of cytokine signaling 2
Ubiquitin system [BR:ko04121]
 Ubiquitin ligases (E3)
  Multi subunit Ring-finger type E3
   ECS complex
    Target recognizing subunit (SOCS box)
     K04695  SOCS2, CIS2; suppressor of cytokine signaling 2
BRITE hierarchy
Genes
HSA: 
8835(SOCS2)
PTR: 
452127(SOCS2)
PPS: 
100989242(SOCS2)
GGO: 
101141962(SOCS2)
PON: 
100440378(SOCS2)
NLE: 
100604289(SOCS2)
MCC: 
715772(SOCS2)
MCF: 
102125352(SOCS2)
CSAB: 
103238870(SOCS2)
RRO: 
104678596(SOCS2)
RBB: 
108527232(SOCS2)
CJC: 
100396208(SOCS2)
SBQ: 
101040467(SOCS2)
MMU: 
216233(Socs2)
RNO: 
84607(Socs2)
NGI: 
103726290(Socs2)
HGL: 
101716580(Socs2)
CCAN: 
109688786(Socs2)
OCU: 
100354019(SOCS2)
TUP: 
102480737(SOCS2)
CFA: 
100855737(SOCS2)
AML: 
100474808(SOCS2)
UMR: 
103660099(SOCS2)
FCA: 
101080980(SOCS2)
PTG: 
102953997(SOCS2)
AJU: 
106973415(SOCS2)
BTA: 
338437(SOCS2)
BOM: 
102268022(SOCS2)
BIU: 
109558981(SOCS2)
PHD: 
102315362(SOCS2)
CHX: 
102178979(SOCS2)
OAS: 
101115017(SOCS2)
SSC: 
100037966(SOCS2)
CFR: 
102505948(SOCS2)
CDK: 
105097413(SOCS2)
BACU: 
LVE: 
103070250(SOCS2)
ECB: 
100051952(SOCS2)
EPZ: 
103564583(SOCS2)
EAI: 
106831177(SOCS2)
MYB: 
102260836(SOCS2)
MYD: 
102764738(SOCS2)
HAI: 
109392673(SOCS2)
RSS: 
109433793(SOCS2)
PALE: 
102889529(SOCS2)
LAV: 
100660067(SOCS2)
MDO: 
100011895(SOCS2)
SHR: 
100925364(SOCS2)
OAA: 
100079417(SOCS2)
GGA: 
395219(SOCS2)
MGP: 
100544272(SOCS2)
CJO: 
107311591(SOCS2)
APLA: 
101790013(SOCS2)
ACYG: 
106036904(SOCS2)
TGU: 
100229201(SOCS2)
GFR: 
102031776(SOCS2)
FAB: 
101816040(SOCS2)
PHI: 
102114276(SOCS2)
PMAJ: 
107204420(SOCS2)
CCW: 
104696565(SOCS2)
FPG: 
106112815(SOCS2)
FCH: 
106631601(SOCS2)
CLV: 
102097346(SOCS2)
AAM: 
106488466(SOCS2)
ASN: 
102388356(SOCS2)
AMJ: 
102574136(SOCS2)
PSS: 
CMY: 
CPIC: 
ACS: 
100552196(socs2)
PVT: 
110091701(SOCS2)
PBI: 
103051048(SOCS2)
GJA: 
107118612(SOCS2)
XLA: 
108711062(socs2.L) 734276(socs2.S)
XTR: 
100151723(socs2)
NPR: 
108790061(SOCS2)
DRE: 
562062(socs2)
SRX: 
SANH: 
SGH: 
IPU: 
TRU: 
100144308(socs2)
TNG: 
LCO: 
104938686(socs2)
NCC: 
104961843(socs2)
MZE: 
101485857(socs2)
OLA: 
XMA: 
CSEM: 
LCF: 
BPEC: 
SASA: 
106567289 106576177(SOCS2a) 106609294(SOCS2b)
ELS: 
105027835(socs2)
SFM: 
108920753(socs2)
LCM: 
CMK: 
103188876(socs2)
BFO: 
SPU: 
BMOR: 
100862764(SOCS2-12)
PXY: 
DPX: 
ISC: 
CRG: 
OBI: 
LAK: 
NVE: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Kile BT, Schulman BA, Alexander WS, Nicola NA, Martin HM, Hilton DJ.
  Title
The SOCS box: a tale of destruction and degradation.
  Journal
Trends Biochem Sci 27:235-41 (2002)
DOI:10.1016/S0968-0004(02)02085-6
  Sequence
[hsa:8835]
Reference
  Authors
Iglesias-Gato D, Chuan YC, Wikstrom P, Augsten S, Jiang N, Niu Y, Seipel A, Danneman D, Vermeij M, Fernandez-Perez L, Jenster G, Egevad L, Norstedt G, Flores-Morales A
  Title
SOCS2 mediates the cross talk between androgen and growth hormone signaling in prostate cancer.
  Journal
Carcinogenesis 35:24-33 (2014)
DOI:10.1093/carcin/bgt304
  Sequence
[hsa:8835]

KEGG   ORTHOLOGY: K04696Help
Entry
K04696                      KO                                     

Name
SOCS3, CIS3
Definition
suppressor of cytokine signaling 3
Pathway
Ubiquitin mediated proteolysis
Osteoclast differentiation
Jak-STAT signaling pathway
TNF signaling pathway
Insulin signaling pathway
Prolactin signaling pathway
Adipocytokine signaling pathway
Type II diabetes mellitus
Insulin resistance
Non-alcoholic fatty liver disease (NAFLD)
Hepatitis C
Influenza A
Herpes simplex infection
Module
M00388  
ECS complex
M00684  
JAK-STAT signaling
Brite
KEGG Orthology (KO) [BR:ko00001]
 Genetic Information Processing
  Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    K04696  SOCS3, CIS3; suppressor of cytokine signaling 3
 Environmental Information Processing
  Signal transduction
   04630 Jak-STAT signaling pathway
    K04696  SOCS3, CIS3; suppressor of cytokine signaling 3
   04668 TNF signaling pathway
    K04696  SOCS3, CIS3; suppressor of cytokine signaling 3
 Organismal Systems
  Endocrine system
   04910 Insulin signaling pathway
    K04696  SOCS3, CIS3; suppressor of cytokine signaling 3
   04920 Adipocytokine signaling pathway
    K04696  SOCS3, CIS3; suppressor of cytokine signaling 3
   04917 Prolactin signaling pathway
    K04696  SOCS3, CIS3; suppressor of cytokine signaling 3
  Development
   04380 Osteoclast differentiation
    K04696  SOCS3, CIS3; suppressor of cytokine signaling 3
 Human Diseases
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    K04696  SOCS3, CIS3; suppressor of cytokine signaling 3
   04932 Non-alcoholic fatty liver disease (NAFLD)
    K04696  SOCS3, CIS3; suppressor of cytokine signaling 3
   04931 Insulin resistance
    K04696  SOCS3, CIS3; suppressor of cytokine signaling 3
  Infectious diseases
   05164 Influenza A
    K04696  SOCS3, CIS3; suppressor of cytokine signaling 3
   05160 Hepatitis C
    K04696  SOCS3, CIS3; suppressor of cytokine signaling 3
   05168 Herpes simplex infection
    K04696  SOCS3, CIS3; suppressor of cytokine signaling 3
KEGG modules [BR:ko00002]
 Structural complex
  Genetic information processing
   Ubiquitin system
    M00388  ECS complex
     K04696  SOCS3, CIS3; suppressor of cytokine signaling 3
 Functional set
  Cellular processes
   Cell signaling
    M00684  JAK-STAT signaling
     K04696  SOCS3, CIS3; suppressor of cytokine signaling 3
Ubiquitin system [BR:ko04121]
 Ubiquitin ligases (E3)
  Multi subunit Ring-finger type E3
   ECS complex
    Target recognizing subunit (SOCS box)
     K04696  SOCS3, CIS3; suppressor of cytokine signaling 3
BRITE hierarchy
Genes
HSA: 
9021(SOCS3)
PTR: 
454921(SOCS3)
PPS: 
100978589(SOCS3)
GGO: 
101123839(SOCS3)
PON: 
100446544(SOCS3)
MCC: 
715680(SOCS3)
MCF: 
102121569(SOCS3)
CSAB: 
103243658(SOCS3)
RRO: 
104677022(SOCS3)
RBB: 
108517203(SOCS3)
CJC: 
100398838(SOCS3)
SBQ: 
101046533(SOCS3)
MMU: 
12702(Socs3)
RNO: 
89829(Socs3)
CGE: 
100769267(Socs3)
NGI: 
103747288(Socs3)
HGL: 
101704157(Socs3)
CCAN: 
109683139(Socs3)
OCU: 
103346588(SOCS3)
TUP: 
102486692(SOCS3)
CFA: 
442949(SOCS3)
AML: 
100475555(SOCS3)
UMR: 
103665967(SOCS3)
FCA: 
101081846(SOCS3)
BTA: 
282081(SOCS3)
BOM: 
102273017(SOCS3)
BIU: 
109574319(SOCS3)
PHD: 
102315804(SOCS3)
CHX: 
102187711(SOCS3)
OAS: 
100294595(SOCS3)
SSC: 
493186(SOCS3)
CFR: 
102518913(SOCS3)
CDK: 
105092151(SOCS3)
BACU: 
103013097(SOCS3)
LVE: 
103071774(SOCS3)
ECB: 
100050730(SOCS3)
EPZ: 
103554055(SOCS3)
EAI: 
106845267(SOCS3)
MYB: 
102252296(SOCS3)
MYD: 
102763837(SOCS3)
HAI: 
109383617(SOCS3)
RSS: 
109449408(SOCS3)
PALE: 
102887834(SOCS3)
LAV: 
100670741(SOCS3)
MDO: 
100026656(SOCS3)
SHR: 
100934360(SOCS3)
OAA: 
100090302(SOCS3)
GGA: 
395299(SOCS3)
MGP: 
100547594(SOCS3)
CJO: 
107322171(SOCS3)
APLA: 
101791200(SOCS3)
ACYG: 
106046730(SOCS3)
TGU: 
100227853(SOCS3)
GFR: 
102044994(SOCS3)
FAB: 
101810199(SOCS3)
PHI: 
102107383(SOCS3)
PMAJ: 
107212347(SOCS3)
FPG: 
101912299(SOCS3)
FCH: 
102058593(SOCS3)
CLV: 
102085285(SOCS3)
AAM: 
106487124(SOCS3)
ASN: 
102386715(SOCS3)
AMJ: 
PSS: 
102446993(SOCS3)
CMY: 
102930798(SOCS3)
CPIC: 
ACS: 
PVT: 
PBI: 
GJA: 
XLA: 
100158303 108696746 380467(socs3.S) 414533(socs3.L)
XTR: 
394588(socs3) 448204(socs3)
NPR: 
DRE: 
406596(socs3b)
SRX: 
SANH: 
SGH: 
IPU: 
TRU: 
TNG: 
LCO: 
NCC: 
MZE: 
OLA: 
101170518(socs3) 101170961(socs3)
XMA: 
CSEM: 
LCF: 
HCQ: 
BPEC: 
SASA: 
ELS: 
SFM: 
LCM: 
CMK: 
103175554(socs3)
BFO: 
ADF: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Kile BT, Schulman BA, Alexander WS, Nicola NA, Martin HM, Hilton DJ.
  Title
The SOCS box: a tale of destruction and degradation.
  Journal
Trends Biochem Sci 27:235-41 (2002)
DOI:10.1016/S0968-0004(02)02085-6
  Sequence
[hsa:9021]
Reference
  Authors
Kamura T, Maenaka K, Kotoshiba S, Matsumoto M, Kohda D, Conaway RC, Conaway JW, Nakayama KI.
  Title
VHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligases.
  Journal
Genes Dev 18:3055-65 (2004)
DOI:10.1101/gad.1252404
  Sequence
[hsa:9021]
Reference
  Authors
Rui L, Yuan M, Frantz D, Shoelson S, White MF.
  Title
SOCS-1 and SOCS-3 block insulin signaling by ubiquitin-mediated degradation of IRS1 and IRS2.
  Journal
J Biol Chem 277:42394-8 (2002)
DOI:10.1074/jbc.C200444200
  Sequence
[hsa:9021] [mmu:12702]

KEGG   ORTHOLOGY: K04697Help
Entry
K04697                      KO                                     

Name
SOCS4
Definition
suppressor of cytokine signaling 4
Pathway
Jak-STAT signaling pathway
Insulin signaling pathway
Prolactin signaling pathway
Type II diabetes mellitus
Module
M00388  
ECS complex
M00684  
JAK-STAT signaling
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04630 Jak-STAT signaling pathway
    K04697  SOCS4; suppressor of cytokine signaling 4
 Organismal Systems
  Endocrine system
   04910 Insulin signaling pathway
    K04697  SOCS4; suppressor of cytokine signaling 4
   04917 Prolactin signaling pathway
    K04697  SOCS4; suppressor of cytokine signaling 4
 Human Diseases
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    K04697  SOCS4; suppressor of cytokine signaling 4
KEGG modules [BR:ko00002]
 Structural complex
  Genetic information processing
   Ubiquitin system
    M00388  ECS complex
     K04697  SOCS4; suppressor of cytokine signaling 4
 Functional set
  Cellular processes
   Cell signaling
    M00684  JAK-STAT signaling
     K04697  SOCS4; suppressor of cytokine signaling 4
Ubiquitin system [BR:ko04121]
 Ubiquitin ligases (E3)
  Multi subunit Ring-finger type E3
   ECS complex
    Target recognizing subunit (SOCS box)
     K04697  SOCS4; suppressor of cytokine signaling 4
BRITE hierarchy
Genes
HSA: 
122809(SOCS4)
PTR: 
452919(SOCS4)
PPS: 
100989690(SOCS4)
GGO: 
101131192(SOCS4)
PON: 
100171842(SOCS4)
NLE: 
100590972(SOCS4)
MCC: 
696146(SOCS4)
MCF: 
102141350(SOCS4)
CSAB: 
103229025(SOCS4)
RRO: 
104669147(SOCS4)
RBB: 
108530661(SOCS4)
CJC: 
100386210(SOCS4)
SBQ: 
101034850(SOCS4)
MMU: 
67296(Socs4)
RNO: 
305828(Socs4)
CGE: 
100750379(Socs4)
NGI: 
103739222(Socs4)
HGL: 
101704725(Socs4)
CCAN: 
109693954(Socs4)
OCU: 
100357417(SOCS4)
TUP: 
102468675(SOCS4)
CFA: 
100687271(SOCS4)
AML: 
100464791(SOCS4)
UMR: 
103673077(SOCS4)
FCA: 
101080974(SOCS4)
PTG: 
102971697(SOCS4)
AJU: 
106984332(SOCS4)
BTA: 
540412(SOCS4)
BOM: 
102270424(SOCS4)
BIU: 
109565183(SOCS4)
PHD: 
102333116(SOCS4)
CHX: 
102185842(SOCS4)
OAS: 
101117935(SOCS4)
SSC: 
100302366(SOCS4)
CFR: 
102515584(SOCS4)
CDK: 
105091440(SOCS4)
BACU: 
103014060(SOCS4)
LVE: 
103076129(SOCS4)
ECB: 
100050301(SOCS4)
EPZ: 
103554102(SOCS4)
EAI: 
106846111(SOCS4)
MYB: 
102247430(SOCS4)
MYD: 
102767035(SOCS4)
HAI: 
109384171(SOCS4)
RSS: 
109444383(SOCS4)
PALE: 
102879275(SOCS4)
LAV: 
100662743(SOCS4)
MDO: 
100024207(SOCS4)
SHR: 
100921040(SOCS4)
OAA: 
GGA: 
423557(SOCS4)
MGP: 
100549827(SOCS4)
CJO: 
107315453(SOCS4)
APLA: 
101804231(SOCS4)
ACYG: 
106044059(SOCS4)
TGU: 
100230629(SOCS4)
GFR: 
102043937(SOCS4)
FAB: 
PHI: 
102109006(SOCS4)
PMAJ: 
107206463(SOCS4)
CCW: 
104687619(SOCS4)
FPG: 
101924304(SOCS4)
FCH: 
102048310(SOCS4)
CLV: 
102086690(SOCS4)
AAM: 
106493674(SOCS4)
ASN: 
102384587(SOCS4)
AMJ: 
102572731(SOCS4)
PSS: 
102453072(SOCS4)
CMY: 
102931468(SOCS4)
CPIC: 
101953043(SOCS4)
ACS: 
100561266(socs4)
PVT: 
110070093(SOCS4)
PBI: 
103053679(SOCS4)
GJA: 
107113082(SOCS4)
XLA: 
108698764(socs4.L) 108699788(socs4.S)
XTR: 
549828(socs4)
NPR: 
108789412(SOCS4)
DRE: 
100003691(socs9)
SRX: 
SANH: 
SGH: 
IPU: 
108270091(SOCS4)
TRU: 
100144313(socs4)
TNG: 
LCO: 
104929608(socs4)
NCC: 
MZE: 
101469365(socs4)
OLA: 
100144385(socs4)
XMA: 
CSEM: 
LCF: 
108888048(socs4)
HCQ: 
SASA: 
106602930(socs4)
ELS: 
105023278(socs4)
SFM: 
LCM: 
102362805(SOCS4)
CMK: 
103175235(socs4)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Kile BT, Schulman BA, Alexander WS, Nicola NA, Martin HM, Hilton DJ.
  Title
The SOCS box: a tale of destruction and degradation.
  Journal
Trends Biochem Sci 27:235-41 (2002)
DOI:10.1016/S0968-0004(02)02085-6
  Sequence
[hsa:122809]
Reference
  Authors
Kario E, Marmor MD, Adamsky K, Citri A, Amit I, Amariglio N, Rechavi G, Yarden Y
  Title
Suppressors of cytokine signaling 4 and 5 regulate epidermal growth factor receptor signaling.
  Journal
J Biol Chem 280:7038-48 (2005)
DOI:10.1074/jbc.M408575200
  Sequence
[hsa:122809]

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