KEGG   ORTHOLOGY: K05208Help
Entry
K05208                      KO                                     

Name
GRIN1
Definition
glutamate receptor ionotropic, NMDA 1
Pathway
Ras signaling pathway
Rap1 signaling pathway
Calcium signaling pathway
cAMP signaling pathway
Neuroactive ligand-receptor interaction
Circadian entrainment
Long-term potentiation
Glutamatergic synapse
Alzheimer's disease
Amyotrophic lateral sclerosis (ALS)
Huntington's disease
Cocaine addiction
Amphetamine addiction
Nicotine addiction
Alcoholism
Disease
H00773  
Autosomal dominant mental retardation
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
   04015 Rap1 signaling pathway
    K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
   04020 Calcium signaling pathway
    K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
   04024 cAMP signaling pathway
    K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
  Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
 Organismal Systems
  Nervous system
   04724 Glutamatergic synapse
    K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
   04720 Long-term potentiation
    K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
  Environmental adaptation
   04713 Circadian entrainment
    K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
 Human Diseases
  Neurodegenerative diseases
   05010 Alzheimer's disease
    K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
   05014 Amyotrophic lateral sclerosis (ALS)
    K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
   05016 Huntington's disease
    K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
  Substance dependence
   05030 Cocaine addiction
    K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
   05031 Amphetamine addiction
    K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
   05033 Nicotine addiction
    K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
   05034 Alcoholism
    K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
Ion channels [BR:ko04040]
 Glutamate-gated cation channels
  Glutamate (ionotropic), NMDA
   K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
BRITE hierarchy
Other DBs
Genes
HSA: 
2902(GRIN1)
PTR: 
465176(GRIN1)
PPS: 
100987673(GRIN1)
GGO: 
101146203(GRIN1)
PON: 
100435177(GRIN1)
NLE: 
100607572(GRIN1)
MCC: 
574380(GRIN1)
MCF: 
102115033(GRIN1)
CSAB: 
103239575(GRIN1)
RRO: 
104669771(GRIN1)
RBB: 
108542864(GRIN1)
CJC: 
100413857(GRIN1)
SBQ: 
101054145(GRIN1)
MMU: 
14810(Grin1)
RNO: 
24408(Grin1)
CGE: 
100770880(Grin1)
NGI: 
103732604(Grin1)
HGL: 
101720185(Grin1)
CCAN: 
TUP: 
102469683(GRIN1)
CFA: 
494007(GRIN1)
AML: 
100465687(GRIN1)
UMR: 
103675310(GRIN1)
FCA: 
101082021(GRIN1)
PTG: 
102949242(GRIN1)
AJU: 
106989187(GRIN1)
BTA: 
100336579(GRIN1)
BOM: 
102276953(GRIN1)
PHD: 
102324204(GRIN1)
CHX: 
102181789(GRIN1)
OAS: 
443281(GRIN1)
CFR: 
102506181(GRIN1)
CDK: 
105106183(GRIN1)
BACU: 
103001022(GRIN1)
LVE: 
103085162(GRIN1)
ECB: 
100059861(GRIN1)
EPZ: 
103563588(GRIN1)
EAI: 
106822778(GRIN1)
MYB: 
102240692(GRIN1)
MYD: 
102751770(GRIN1)
HAI: 
109382502(GRIN1)
RSS: 
109460938(GRIN1)
PALE: 
102894415(GRIN1)
LAV: 
100663779(GRIN1)
MDO: 
100023485(GRIN1)
SHR: 
100922600(GRIN1)
OAA: 
100082705(GRIN1)
GGA: 
404296(GRIN1)
MGP: 
100548054(GRIN1)
CJO: 
107321672(GRIN1)
APLA: 
101789524(GRIN1)
ACYG: 
106037054(GRIN1)
TGU: 
751779(GRIN1)
GFR: 
102040955(GRIN1)
FAB: 
101818610(GRIN1)
PHI: 
102108893(GRIN1)
PMAJ: 
107212141(GRIN1)
CCW: 
104688213(GRIN1)
FPG: 
101913185(GRIN1)
FCH: 
102047364(GRIN1)
CLV: 
102098434(GRIN1)
AAM: 
106487018(GRIN1)
ASN: 
102370900(GRIN1)
AMJ: 
102571725(GRIN1)
PSS: 
102453445(GRIN1)
CMY: 
CPIC: 
101935314(GRIN1)
ACS: 
100553024(grin1)
PVT: 
110087451(GRIN1)
PBI: 
103066289(GRIN1)
GJA: 
107115159(GRIN1)
XLA: 
108699855 397953(grin1.S)
XTR: 
780048(grin1)
NPR: 
108795933(GRIN1)
DRE: 
100005675(grin1b) 767745(grin1a)
SRX: 
SANH: 
SGH: 
IPU: 
AMEX: 
TRU: 
TNG: 
LCO: 
104936329(grin1)
NCC: 
MZE: 
OLA: 
XMA: 
102220646(grin1)
CSEM: 
LCF: 
HCQ: 
BPEC: 
SASA: 
ELS: 
SFM: 
LCM: 
102356038(GRIN1)
CMK: 
103183009(grin1)
BFO: 
CIN: 
SKO: 
DME: 
Dmel_CG2902(Nmdar1)
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
Dsimw501_GD19612(Dsim_GD19612)
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
MDE: 
AGA: 
AAG: 
CQU: 
AME: 
406079(Nmdar1)
BIM: 
BTER: 
SOC: 
AEC: 
ACEP: 
PBAR: 
HST: 
CFO: 
LHU: 
PGC: 
TCA: 
DPA: 
NVL: 
BMOR: 
DPL: 
PXY: 
API: 
DNX: 
PHU: 
FCD: 
DPX: 
ISC: 
TUT: 
CEL: 
CBR: 
CBG02401(Cbr-nmr-1)
NAI: 
LGI: 
CRG: 
OBI: 
LAK: 
SMM: 
SHX: 
OVI: 
NVE: 
ADF: 
HMG: 
 » show all
TaxonomyKoalaUniProt
Reference
PMID:7685113
  Authors
Planells-Cases R, Sun W, Ferrer-Montiel AV, Montal M
  Title
Molecular cloning, functional expression, and pharmacological characterization of an N-methyl-D-aspartate receptor subunit from human brain.
  Journal
Proc Natl Acad Sci U S A 90:5057-61 (1993)
DOI:10.1073/pnas.90.11.5057
  Sequence
[hsa:2902]

KEGG   ORTHOLOGY: K05209Help
Entry
K05209                      KO                                     

Name
GRIN2A
Definition
glutamate receptor ionotropic, NMDA 2A
Pathway
Ras signaling pathway
Rap1 signaling pathway
Calcium signaling pathway
cAMP signaling pathway
Neuroactive ligand-receptor interaction
Circadian entrainment
Long-term potentiation
Glutamatergic synapse
Dopaminergic synapse
Alzheimer's disease
Amyotrophic lateral sclerosis (ALS)
Cocaine addiction
Amphetamine addiction
Nicotine addiction
Alcoholism
Systemic lupus erythematosus
Disease
H01514  
Landau-Kleffner syndrome
H01827  
Epileptic encephalopathy with continuous spike-waves during slow-wave sleep
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    K05209  GRIN2A; glutamate receptor ionotropic, NMDA 2A
   04015 Rap1 signaling pathway
    K05209  GRIN2A; glutamate receptor ionotropic, NMDA 2A
   04020 Calcium signaling pathway
    K05209  GRIN2A; glutamate receptor ionotropic, NMDA 2A
   04024 cAMP signaling pathway
    K05209  GRIN2A; glutamate receptor ionotropic, NMDA 2A
  Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K05209  GRIN2A; glutamate receptor ionotropic, NMDA 2A
 Organismal Systems
  Nervous system
   04724 Glutamatergic synapse
    K05209  GRIN2A; glutamate receptor ionotropic, NMDA 2A
   04728 Dopaminergic synapse
    K05209  GRIN2A; glutamate receptor ionotropic, NMDA 2A
   04720 Long-term potentiation
    K05209  GRIN2A; glutamate receptor ionotropic, NMDA 2A
  Environmental adaptation
   04713 Circadian entrainment
    K05209  GRIN2A; glutamate receptor ionotropic, NMDA 2A
 Human Diseases
  Immune diseases
   05322 Systemic lupus erythematosus
    K05209  GRIN2A; glutamate receptor ionotropic, NMDA 2A
  Neurodegenerative diseases
   05010 Alzheimer's disease
    K05209  GRIN2A; glutamate receptor ionotropic, NMDA 2A
   05014 Amyotrophic lateral sclerosis (ALS)
    K05209  GRIN2A; glutamate receptor ionotropic, NMDA 2A
  Substance dependence
   05030 Cocaine addiction
    K05209  GRIN2A; glutamate receptor ionotropic, NMDA 2A
   05031 Amphetamine addiction
    K05209  GRIN2A; glutamate receptor ionotropic, NMDA 2A
   05033 Nicotine addiction
    K05209  GRIN2A; glutamate receptor ionotropic, NMDA 2A
   05034 Alcoholism
    K05209  GRIN2A; glutamate receptor ionotropic, NMDA 2A
Ion channels [BR:ko04040]
 Glutamate-gated cation channels
  Glutamate (ionotropic), NMDA
   K05209  GRIN2A; glutamate receptor ionotropic, NMDA 2A
BRITE hierarchy
Other DBs
Genes
HSA: 
2903(GRIN2A)
PTR: 
454396(GRIN2A)
PPS: 
100977852(GRIN2A)
GGO: 
101124569(GRIN2A)
PON: 
100438553(GRIN2A)
NLE: 
100584731(GRIN2A)
MCC: 
100429880(GRIN2A)
MCF: 
102123126(GRIN2A)
CSAB: 
103228072(GRIN2A)
RRO: 
104667722(GRIN2A)
RBB: 
108541249(GRIN2A)
CJC: 
100411569(GRIN2A)
SBQ: 
101030380(GRIN2A)
MMU: 
14811(Grin2a)
RNO: 
24409(Grin2a)
CGE: 
100764315(Grin2a)
NGI: 
103731589(Grin2a)
HGL: 
101716707(Grin2a)
CCAN: 
OCU: 
100337889(GRIN2A)
TUP: 
102487925(GRIN2A)
CFA: 
490012(GRIN2A)
AML: 
100469843(GRIN2A)
UMR: 
103668590(GRIN2A)
FCA: 
101086110(GRIN2A)
PTG: 
102969126(GRIN2A)
AJU: 
BTA: 
524212(GRIN2A)
BOM: 
102283831(GRIN2A)
BIU: 
109578088(GRIN2A)
PHD: 
102324750(GRIN2A)
CHX: 
102189537(GRIN2A)
OAS: 
101106989(GRIN2A)
SSC: 
100736832(GRIN2A)
CFR: 
102503788(GRIN2A)
CDK: 
105089056(GRIN2A)
BACU: 
103006151(GRIN2A)
LVE: 
103091670(GRIN2A)
ECB: 
100051329(GRIN2A)
EPZ: 
103555146(GRIN2A)
EAI: 
MYB: 
102245838(GRIN2A)
MYD: 
102771313(GRIN2A)
HAI: 
109387184(GRIN2A)
RSS: 
PALE: 
102898336(GRIN2A)
LAV: 
100658424(GRIN2A)
MDO: 
100018255(GRIN2A)
SHR: 
100920008(GRIN2A)
OAA: 
100074436(GRIN2A)
GGA: 
427678(GRIN2A)
MGP: 
CJO: 
107320868(GRIN2A)
APLA: 
101804769(GRIN2A)
ACYG: 
106041218(GRIN2A)
TGU: 
778440(GRIN2A)
GFR: 
102042287(GRIN2A)
FAB: 
101819385(GRIN2A)
PHI: 
102113741(GRIN2A)
PMAJ: 
107211300(GRIN2A)
CCW: 
104684701(GRIN2A)
FPG: 
101912351(GRIN2A)
FCH: 
102048497(GRIN2A)
CLV: 
102091639(GRIN2A)
AAM: 
106482645(GRIN2A)
ASN: 
102373605(GRIN2A)
AMJ: 
102565271(GRIN2A)
PSS: 
102459849(GRIN2A)
CMY: 
102936101(GRIN2A)
CPIC: 
101933703(GRIN2A)
ACS: 
100557524(grin2a)
PVT: 
110087033(GRIN2A)
PBI: 
103060162(GRIN2A)
GJA: 
107111188(GRIN2A)
XLA: 
100126660(nr2a) 100127346(grin2a.L)
XTR: 
100489006(grin2a)
NPR: 
108794358(GRIN2A)
DRE: 
563297(grin2aa) 570493(grin2ab)
SRX: 
SANH: 
SGH: 
IPU: 
AMEX: 
TRU: 
TNG: 
LCO: 
NCC: 
MZE: 
OLA: 
XMA: 
CSEM: 
LCF: 
HCQ: 
BPEC: 
SASA: 
ELS: 
SFM: 
LCM: 
102359367(GRIN2A)
CMK: 
103186084(grin2a)
BFO: 
CIN: 
SKO: 
 » show all
TaxonomyKoalaUniProt
Reference
PMID:8428958
  Authors
Ishii T, Moriyoshi K, Sugihara H, Sakurada K, Kadotani H, Yokoi M, Akazawa C, Shigemoto R, Mizuno N, Masu M, et al.
  Title
Molecular characterization of the family of the N-methyl-D-aspartate receptor subunits.
  Journal
J Biol Chem 268:2836-43 (1993)
  Sequence
[rno:24409]

KEGG   ORTHOLOGY: K05211Help
Entry
K05211                      KO                                     

Name
GRIN2C
Definition
glutamate receptor ionotropic, NMDA 2C
Pathway
Calcium signaling pathway
cAMP signaling pathway
Neuroactive ligand-receptor interaction
Circadian entrainment
Long-term potentiation
Glutamatergic synapse
Alzheimer's disease
Amyotrophic lateral sclerosis (ALS)
Cocaine addiction
Amphetamine addiction
Nicotine addiction
Alcoholism
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04020 Calcium signaling pathway
    K05211  GRIN2C; glutamate receptor ionotropic, NMDA 2C
   04024 cAMP signaling pathway
    K05211  GRIN2C; glutamate receptor ionotropic, NMDA 2C
  Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K05211  GRIN2C; glutamate receptor ionotropic, NMDA 2C
 Organismal Systems
  Nervous system
   04724 Glutamatergic synapse
    K05211  GRIN2C; glutamate receptor ionotropic, NMDA 2C
   04720 Long-term potentiation
    K05211  GRIN2C; glutamate receptor ionotropic, NMDA 2C
  Environmental adaptation
   04713 Circadian entrainment
    K05211  GRIN2C; glutamate receptor ionotropic, NMDA 2C
 Human Diseases
  Neurodegenerative diseases
   05010 Alzheimer's disease
    K05211  GRIN2C; glutamate receptor ionotropic, NMDA 2C
   05014 Amyotrophic lateral sclerosis (ALS)
    K05211  GRIN2C; glutamate receptor ionotropic, NMDA 2C
  Substance dependence
   05030 Cocaine addiction
    K05211  GRIN2C; glutamate receptor ionotropic, NMDA 2C
   05031 Amphetamine addiction
    K05211  GRIN2C; glutamate receptor ionotropic, NMDA 2C
   05033 Nicotine addiction
    K05211  GRIN2C; glutamate receptor ionotropic, NMDA 2C
   05034 Alcoholism
    K05211  GRIN2C; glutamate receptor ionotropic, NMDA 2C
Ion channels [BR:ko04040]
 Glutamate-gated cation channels
  Glutamate (ionotropic), NMDA
   K05211  GRIN2C; glutamate receptor ionotropic, NMDA 2C
BRITE hierarchy
Other DBs
Genes
HSA: 
2905(GRIN2C)
PTR: 
454868(GRIN2C)
PPS: 
100989438(GRIN2C)
GGO: 
101146970(GRIN2C)
PON: 
100436723(GRIN2C)
NLE: 
100607001(GRIN2C)
MCC: 
699216(GRIN2C)
MCF: 
102135755(GRIN2C)
CSAB: 
103243074(GRIN2C)
RRO: 
104681333(GRIN2C)
RBB: 
108537403(GRIN2C)
CJC: 
100388195(GRIN2C)
SBQ: 
101040894(GRIN2C)
MMU: 
14813(Grin2c)
RNO: 
24411(Grin2c)
CGE: 
100758804(Grin2c)
NGI: 
103732757(Grin2c)
HGL: 
101698922(Grin2c)
CCAN: 
109683576(Grin2c)
OCU: 
100356338(GRIN2C)
TUP: 
102479118(GRIN2C)
CFA: 
483302(GRIN2C)
AML: 
100475562(GRIN2C)
UMR: 
103665926(GRIN2C)
FCA: 
101091740(GRIN2C)
PTG: 
102959236(GRIN2C)
AJU: 
106987730(GRIN2C)
BTA: 
535158(GRIN2C)
BOM: 
102272710(GRIN2C)
BIU: 
109573357(GRIN2C)
PHD: 
102325114(GRIN2C)
CHX: 
102177097(GRIN2C)
OAS: 
101102915(GRIN2C)
SSC: 
100515684(GRIN2C)
CFR: 
102516268(GRIN2C)
CDK: 
105104658(GRIN2C)
BACU: 
103008767(GRIN2C)
LVE: 
103086451(GRIN2C)
ECB: 
100052410(GRIN2C)
EPZ: 
103546604(GRIN2C)
EAI: 
106830197(GRIN2C)
MYB: 
102264015(GRIN2C)
MYD: 
102775005(GRIN2C)
HAI: 
109383627(GRIN2C)
RSS: 
109454718(GRIN2C)
PALE: 
102881285(GRIN2C)
LAV: 
100656237(GRIN2C)
MDO: 
100028018(GRIN2C)
SHR: 
100922827(GRIN2C)
GGA: 
431090(GRIN2C)
MGP: 
100540247(GRIN2C)
CJO: 
107322357(GRIN2C)
APLA: 
101800611(GRIN2C)
ACYG: 
106034618(GRIN2C)
TGU: 
778441(GRIN2C)
GFR: 
102034349(GRIN2C)
FAB: 
101812781(GRIN2C)
PHI: 
102102883(GRIN2C)
PMAJ: 
107212243(GRIN2C)
CCW: 
104694369(GRIN2C)
FPG: 
101910725(GRIN2C)
FCH: 
102046514(GRIN2C)
CLV: 
102089298(GRIN2C)
AAM: 
106492603(GRIN2C)
ASN: 
102372791(GRIN2C)
AMJ: 
102563653(GRIN2C)
PSS: 
102458166(GRIN2C)
CMY: 
102939529(GRIN2C)
CPIC: 
101952683(GRIN2C)
ACS: 
100560039(grin2c)
PVT: 
110085794(GRIN2C)
PBI: 
GJA: 
107110013(GRIN2C)
XLA: 
XTR: 
100496638(grin2c)
NPR: 
108797027(GRIN2C)
DRE: 
100333648(grin2cb)
SRX: 
SANH: 
SGH: 
IPU: 
AMEX: 
TRU: 
TNG: 
LCO: 
NCC: 
MZE: 
OLA: 
XMA: 
CSEM: 
LCF: 
HCQ: 
BPEC: 
SASA: 
ELS: 
SFM: 
LCM: 
102364888(GRIN2C)
CMK: 
103175724(grin2c)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:8428958
  Authors
Ishii T, Moriyoshi K, Sugihara H, Sakurada K, Kadotani H, Yokoi M, Akazawa C, Shigemoto R, Mizuno N, Masu M, et al.
  Title
Molecular characterization of the family of the N-methyl-D-aspartate receptor subunits.
  Journal
J Biol Chem 268:2836-43 (1993)
  Sequence
[rno:24411]

KEGG   ORTHOLOGY: K05212Help
Entry
K05212                      KO                                     

Name
GRIN2D
Definition
glutamate receptor ionotropic, NMDA 2D
Pathway
Calcium signaling pathway
cAMP signaling pathway
Neuroactive ligand-receptor interaction
Circadian entrainment
Long-term potentiation
Glutamatergic synapse
Alzheimer's disease
Amyotrophic lateral sclerosis (ALS)
Cocaine addiction
Amphetamine addiction
Nicotine addiction
Alcoholism
Disease
H00606  
Early infantile epileptic encephalopathy
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04020 Calcium signaling pathway
    K05212  GRIN2D; glutamate receptor ionotropic, NMDA 2D
   04024 cAMP signaling pathway
    K05212  GRIN2D; glutamate receptor ionotropic, NMDA 2D
  Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K05212  GRIN2D; glutamate receptor ionotropic, NMDA 2D
 Organismal Systems
  Nervous system
   04724 Glutamatergic synapse
    K05212  GRIN2D; glutamate receptor ionotropic, NMDA 2D
   04720 Long-term potentiation
    K05212  GRIN2D; glutamate receptor ionotropic, NMDA 2D
  Environmental adaptation
   04713 Circadian entrainment
    K05212  GRIN2D; glutamate receptor ionotropic, NMDA 2D
 Human Diseases
  Neurodegenerative diseases
   05010 Alzheimer's disease
    K05212  GRIN2D; glutamate receptor ionotropic, NMDA 2D
   05014 Amyotrophic lateral sclerosis (ALS)
    K05212  GRIN2D; glutamate receptor ionotropic, NMDA 2D
  Substance dependence
   05030 Cocaine addiction
    K05212  GRIN2D; glutamate receptor ionotropic, NMDA 2D
   05031 Amphetamine addiction
    K05212  GRIN2D; glutamate receptor ionotropic, NMDA 2D
   05033 Nicotine addiction
    K05212  GRIN2D; glutamate receptor ionotropic, NMDA 2D
   05034 Alcoholism
    K05212  GRIN2D; glutamate receptor ionotropic, NMDA 2D
Ion channels [BR:ko04040]
 Glutamate-gated cation channels
  Glutamate (ionotropic), NMDA
   K05212  GRIN2D; glutamate receptor ionotropic, NMDA 2D
BRITE hierarchy
Other DBs
Genes
HSA: 
2906(GRIN2D)
PTR: 
456180(GRIN2D)
PPS: 
100977548(GRIN2D)
GGO: 
101128942(GRIN2D)
PON: 
100438953(GRIN2D)
NLE: 
100589972(GRIN2D)
MCC: 
717945(GRIN2D)
MCF: 
102142969(GRIN2D)
CSAB: 
103234973(GRIN2D)
RRO: 
104666582(GRIN2D)
RBB: 
CJC: 
100401859(GRIN2D)
SBQ: 
101036810(GRIN2D)
MMU: 
14814(Grin2d)
RNO: 
24412(Grin2d)
CGE: 
100750615(Grin2d)
NGI: 
103743747(Grin2d)
HGL: 
101710918(Grin2d)
CCAN: 
109682664(Grin2d)
TUP: 
102498157(GRIN2D)
CFA: 
484405(GRIN2D)
AML: 
100473622(GRIN2D)
UMR: 
103657232(GRIN2D)
FCA: 
101095061(GRIN2D)
PTG: 
102960299(GRIN2D)
AJU: 
106986956(GRIN2D)
BTA: 
618181(GRIN2D)
BOM: 
102266852(GRIN2D)
BIU: 
109571774(GRIN2D)
PHD: 
102322225(GRIN2D)
CHX: 
102177187(GRIN2D)
OAS: 
101105943(GRIN2D)
SSC: 
100521797(GRIN2D)
CFR: 
102522985(GRIN2D)
CDK: 
105098957(GRIN2D)
BACU: 
103006149(GRIN2D)
LVE: 
103076743(GRIN2D)
EPZ: 
103541380(GRIN2D)
EAI: 
106838305(GRIN2D)
MYB: 
102257658(GRIN2D)
MYD: 
102765234(GRIN2D)
HAI: 
109390975(GRIN2D)
RSS: 
109452505(GRIN2D)
PALE: 
102887718(GRIN2D)
LAV: 
100653538(GRIN2D)
MDO: 
100033038(GRIN2D)
CJO: 
ACYG: 
GFR: 
FAB: 
PHI: 
102106210(GRIN2D)
FPG: 
FCH: 
ASN: 
102372349(GRIN2D)
AMJ: 
102573615(GRIN2D)
PSS: 
102460750(GRIN2D)
CMY: 
102931194(GRIN2D)
CPIC: 
101943360(GRIN2D)
ACS: 
100556989(grin2d)
PVT: 
110081819(GRIN2D)
PBI: 
103048165(GRIN2D)
GJA: 
107113157(GRIN2D)
XLA: 
XTR: 
100496465(grin2d)
NPR: 
108784206(GRIN2D)
DRE: 
100149482 449864(grin2da)
SRX: 
SANH: 
SGH: 
IPU: 
AMEX: 
TRU: 
TNG: 
LCO: 
NCC: 
MZE: 
OLA: 
XMA: 
CSEM: 
LCF: 
HCQ: 
BPEC: 
SASA: 
ELS: 
SFM: 
LCM: 
102365417(GRIN2D)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:9489750
  Authors
Hess SD, Daggett LP, Deal C, Lu CC, Johnson EC, Velicelebi G
  Title
Functional characterization of human N-methyl-D-aspartate subtype 1A/2D receptors.
  Journal
J Neurochem 70:1269-79 (1998)
DOI:10.1046/j.1471-4159.1998.70031269.x
  Sequence
[hsa:2906]

KEGG   ORTHOLOGY: K05215Help
Entry
K05215                      KO                                     

Name
P2RX1
Definition
P2X purinoceptor 1
Pathway
Calcium signaling pathway
Neuroactive ligand-receptor interaction
Platelet activation
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04020 Calcium signaling pathway
    K05215  P2RX1; P2X purinoceptor 1
  Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K05215  P2RX1; P2X purinoceptor 1
 Organismal Systems
  Immune system
   04611 Platelet activation
    K05215  P2RX1; P2X purinoceptor 1
Ion channels [BR:ko04040]
 Epithelial and related channels
  ATP-gated cation channel (P2X)
   K05215  P2RX1; P2X purinoceptor 1
BRITE hierarchy
Other DBs
Genes
HSA: 
5023(P2RX1)
PTR: 
454439(P2RX1)
PPS: 
100994570(P2RX1)
GGO: 
101124328(P2RX1)
PON: 
100450049(P2RX1)
NLE: 
100595361(P2RX1)
MCC: 
707658(P2RX1)
MCF: 
102146852(P2RX1)
CSAB: 
103242171(P2RX1)
RRO: 
104677227(P2RX1)
RBB: 
108520720(P2RX1)
CJC: 
100414268(P2RX1)
SBQ: 
101034335(P2RX1)
MMU: 
18436(P2rx1)
RNO: 
25505(P2rx1)
CGE: 
100756069(P2rx1)
NGI: 
103751989(P2rx1)
HGL: 
101722936(P2rx1)
CCAN: 
109694318(P2rx1)
OCU: 
100350587(P2RX1)
TUP: 
102478169(P2RX1)
CFA: 
491223(P2RX1)
AML: 
100463691(P2RX1)
UMR: 
103667126(P2RX1)
FCA: 
101091060(P2RX1)
PTG: 
102963241(P2RX1)
AJU: 
106987363(P2RX1)
BTA: 
514898(P2RX1)
BOM: 
102278561(P2RX1)
BIU: 
109573594(P2RX1)
PHD: 
102314849(P2RX1)
CHX: 
102180347(P2RX1)
OAS: 
101101902(P2RX1)
SSC: 
106504105(P2RX1) 503667(CAMKK1)
CFR: 
102513760(P2RX1)
CDK: 
105095744(P2RX1)
BACU: 
103009121(P2RX1)
LVE: 
103075554(P2RX1)
ECB: 
100060689(P2RX1)
EPZ: 
103558306(P2RX1)
EAI: 
106825737(P2RX1)
MYB: 
102239604(P2RX1)
MYD: 
102753864(P2RX1)
HAI: 
109391888(P2RX1)
RSS: 
109453782(P2RX1)
PALE: 
102881068(P2RX1)
LAV: 
100671204(P2RX1)
MDO: 
100031997(P2RX1)
OAA: 
100087194(P2RX1)
GGA: 
395190(P2RX1)
MGP: 
100541424(P2RX1)
CJO: 
107322652(P2RX1)
APLA: 
101804477(P2RX1)
ACYG: 
106041500(P2RX1)
TGU: 
100219427(P2RX1)
GFR: 
102041318(P2RX1)
FAB: 
101815231(P2RX1)
PHI: 
102102022(P2RX1)
PMAJ: 
107212650(P2RX1)
CCW: 
104691126(P2RX1)
FPG: 
101924292(P2RX1)
FCH: 
102059123(P2RX1)
CLV: 
102093190(P2RX1)
AAM: 
ASN: 
102371579(P2RX1)
AMJ: 
102564148(P2RX1)
PSS: 
102446259(P2RX1)
CMY: 
102946676(P2RX1)
CPIC: 
101944607(P2RX1)
PVT: 
110075497(P2RX1)
PBI: 
103066551(P2RX1)
GJA: 
107107675(P2RX1)
XLA: 
108708358(p2rx1.L) 108708940(p2rx1.S)
XTR: 
100485618(p2rx1)
NPR: 
108784527(P2RX1)
DRE: 
387296(p2rx1)
SRX: 
SANH: 
SGH: 
IPU: 
108260336(p2rx1)
AMEX: 
103022360(p2rx1)
TRU: 
101077982(p2rx1)
TNG: 
LCO: 
104928779(p2rx1)
NCC: 
104961815(p2rx1)
MZE: 
101469120(p2rx1)
OLA: 
101169631(p2rx1)
XMA: 
102233584(p2rx1)
CSEM: 
103395211(p2rx1)
LCF: 
108893661(p2rx1)
HCQ: 
109531111(p2rx1)
BPEC: 
110165084(p2rx1)
SASA: 
ELS: 
105025948(p2rx1)
SFM: 
108928068(p2rx1)
LCM: 
102348549(P2RX1)
CMK: 
103172400(p2rx1)
FCD: 
 » show all
TaxonomyKoalaUniProt
Reference
PMID:7523951
  Authors
Valera S, Hussy N, Evans RJ, Adami N, North RA, Surprenant A, Buell G
  Title
A new class of ligand-gated ion channel defined by P2x receptor for extracellular ATP.
  Journal
Nature 371:516-9 (1994)
DOI:10.1038/371516a0
  Sequence
[rno:25505]

KEGG   ORTHOLOGY: K05216Help
Entry
K05216                      KO                                     

Name
P2RX2
Definition
P2X purinoceptor 2
Pathway
Calcium signaling pathway
Neuroactive ligand-receptor interaction
Taste transduction
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04020 Calcium signaling pathway
    K05216  P2RX2; P2X purinoceptor 2
  Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K05216  P2RX2; P2X purinoceptor 2
 Organismal Systems
  Sensory system
   04742 Taste transduction
    K05216  P2RX2; P2X purinoceptor 2
Ion channels [BR:ko04040]
 Epithelial and related channels
  ATP-gated cation channel (P2X)
   K05216  P2RX2; P2X purinoceptor 2
BRITE hierarchy
Other DBs
Genes
HSA: 
22953(P2RX2)
PTR: 
100615394(P2RX2)
PPS: 
100973505(P2RX2)
GGO: 
101124304(P2RX2)
PON: 
100455448(P2RX2)
NLE: 
100586671(P2RX2)
MCC: 
693390(P2RX2)
MCF: 
102121756(P2RX2)
CSAB: 
103239451(P2RX2)
RRO: 
104674327(P2RX2)
RBB: 
108544495(P2RX2)
CJC: 
100406252(P2RX2)
SBQ: 
101028224(P2RX2)
MMU: 
231602(P2rx2)
RNO: 
114115(P2rx2)
CGE: 
100770815(P2rx2)
NGI: 
103750602(P2rx2)
HGL: 
101719917(P2rx2)
CCAN: 
109686266(P2rx2)
OCU: 
100356670(P2RX2)
TUP: 
102473926(P2RX2)
CFA: 
448781(P2RX2)
AML: 
100468510(P2RX2)
UMR: 
103678891(P2RX2)
FCA: 
751616(P2RX2)
PTG: 
102963320(P2RX2)
AJU: 
106985892(P2RX2)
BTA: 
527499(P2RX2)
BOM: 
102275962(P2RX2)
BIU: 
109570897(P2RX2)
PHD: 
102335445(P2RX2)
CHX: 
102171362(P2RX2)
OAS: 
101116428(P2RX2)
SSC: 
100736581(P2RX2)
CFR: 
102509791(P2RX2)
CDK: 
105104095(P2RX2)
BACU: 
102998993(P2RX2)
LVE: 
103075363(P2RX2)
ECB: 
100061704(P2RX2)
EPZ: 
103561639(P2RX2)
EAI: 
106843862(P2RX2)
MYB: 
102242465(P2RX2)
MYD: 
102770010(P2RX2)
HAI: 
109376154(P2RX2)
RSS: 
PALE: 
102891282(P2RX2)
LAV: 
100654833(P2RX2)
MDO: 
100027526(P2RX2)
SHR: 
100930241(P2RX2)
OAA: 
100080197(P2RX2)
GGA: 
101749217(P2RX2)
MGP: 
100546669(P2RX2)
CJO: 
107321092(P2RX2)
APLA: 
101790466(P2RX2)
ACYG: 
106047467(P2RX2)
AAM: 
106487396(P2RX2)
ASN: 
102383977(P2RX2)
AMJ: 
102563325(P2RX2)
PSS: 
102447498(P2RX2)
CMY: 
102936772(P2RX2)
CPIC: 
101946583(P2RX2)
ACS: 
100553798(p2rx2)
PVT: 
110082885(P2RX2)
PBI: 
103049513(P2RX2)
GJA: 
107122109(P2RX2)
XLA: 
XTR: 
101730278(p2rx2)
NPR: 
108786245(P2RX2)
DRE: 
387297(p2rx2)
SRX: 
107741507(p2rx2)
SANH: 
SGH: 
107599138(p2rx2)
IPU: 
108255423(p2rx2)
AMEX: 
TRU: 
101079700(p2rx2)
TNG: 
LCO: 
104921248(p2rx2)
NCC: 
104945036(p2rx2)
MZE: 
101477055(p2rx2)
OLA: 
101171837(p2rx2)
XMA: 
102217025(p2rx6)
CSEM: 
103397305(p2rx2)
LCF: 
108878121(p2rx2)
HCQ: 
BPEC: 
110156760(p2rx2)
SASA: 
ELS: 
SFM: 
108932542(p2rx2)
LCM: 
102355205(P2RX2)
CMK: 
103184094(p2rx2)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:7523952
  Authors
Brake AJ, Wagenbach MJ, Julius D
  Title
New structural motif for ligand-gated ion channels defined by an ionotropic ATP receptor.
  Journal
Nature 371:519-23 (1994)
DOI:10.1038/371519a0
  Sequence
[rno:114115]

KEGG   ORTHOLOGY: K05217Help
Entry
K05217                      KO                                     

Name
P2RX3
Definition
P2X purinoceptor 3
Pathway
Calcium signaling pathway
Neuroactive ligand-receptor interaction
Taste transduction
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04020 Calcium signaling pathway
    K05217  P2RX3; P2X purinoceptor 3
  Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K05217  P2RX3; P2X purinoceptor 3
 Organismal Systems
  Sensory system
   04742 Taste transduction
    K05217  P2RX3; P2X purinoceptor 3
Ion channels [BR:ko04040]
 Epithelial and related channels
  ATP-gated cation channel (P2X)
   K05217  P2RX3; P2X purinoceptor 3
BRITE hierarchy
Other DBs
Genes
HSA: 
5024(P2RX3)
PTR: 
742961(P2RX3)
PPS: 
100970270(P2RX3)
GGO: 
101127799(P2RX3)
PON: 
100433053(P2RX3)
NLE: 
100579316(P2RX3)
MCC: 
706503(P2RX3)
MCF: 
102141471(P2RX3)
CSAB: 
103235472(P2RX3)
RRO: 
104654292(P2RX3)
RBB: 
108514836(P2RX3)
CJC: 
100414073(P2RX3)
SBQ: 
101044762(P2RX3)
MMU: 
228139(P2rx3)
RNO: 
81739(P2rx3)
CGE: 
100758483(P2rx3)
NGI: 
103736625(P2rx3)
HGL: 
101709018(P2rx3)
CCAN: 
109688996(P2rx3)
OCU: 
100348378(P2RX3)
TUP: 
102484409(P2RX3)
CFA: 
448782(P2RX3)
AML: 
100476571(P2RX3)
UMR: 
103666110(P2RX3)
FCA: 
751615(P2RX3)
PTG: 
102958774(P2RX3)
AJU: 
106979540(P2RX3)
BTA: 
530468(P2RX3)
BOM: 
102281864(P2RX3)
BIU: 
109570043(P2RX3)
PHD: 
102339075(P2RX3)
CHX: 
102180244(P2RX3)
OAS: 
101104779(P2RX3)
SSC: 
503656(P2RX3)
CFR: 
102513517(P2RX3)
CDK: 
105101234(P2RX3)
BACU: 
103003289(P2RX3)
LVE: 
103069544(P2RX3)
ECB: 
100062797(P2RX3)
EPZ: 
103562637(P2RX3)
EAI: 
106823596(P2RX3)
MYB: 
102258212(P2RX3)
MYD: 
102763269(P2RX3)
HAI: 
109371600(P2RX3)
RSS: 
109435479(P2RX3)
PALE: 
102884379(P2RX3)
LAV: 
100656067(P2RX3)
MDO: 
100022565(P2RX3)
SHR: 
100929173(P2RX3)
OAA: 
100086691(P2RX3)
GGA: 
MGP: 
100538989(P2RX3)
CJO: 
107314411(P2RX3)
GFR: 
102033509(P2RX3)
FAB: 
101805978(P2RX3)
PHI: 
102113330(P2RX3)
PMAJ: 
107205424(P2RX3)
FPG: 
101917477(P2RX3)
FCH: 
102053313(P2RX3)
CLV: 
102090857(P2RX3)
ASN: 
102382186(P2RX3)
AMJ: 
102572929(P2RX3)
PSS: 
102444736(P2RX3)
CMY: 
102931043(P2RX3)
CPIC: 
101930829(P2RX3)
ACS: 
100567834(p2rx3)
PVT: 
110078364(P2RX3)
PBI: 
103049490(P2RX3)
GJA: 
107111159(P2RX3)
NPR: 
108797057(P2RX3)
DRE: 
387300(p2rx3b) 58147(p2rx3a)
SRX: 
SANH: 
SGH: 
IPU: 
AMEX: 
TRU: 
TNG: 
LCO: 
NCC: 
MZE: 
OLA: 
XMA: 
CSEM: 
LCF: 
HCQ: 
BPEC: 
SASA: 
ELS: 
SFM: 
LCM: 
102347407(P2RX3)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:9016352
  Authors
Garcia-Guzman M, Soto F, Gomez-Hernandez JM, Lund PE, Stuhmer W
  Title
Characterization of recombinant human P2X4 receptor reveals pharmacological differences to the rat homologue.
  Journal
Mol Pharmacol 51:109-18 (1997)
DOI:10.1124/mol.51.1.109
  Sequence
[hsa:5024]

KEGG   ORTHOLOGY: K05218Help
Entry
K05218                      KO                                     

Name
P2RX4
Definition
P2X purinoceptor 4
Pathway
Calcium signaling pathway
Neuroactive ligand-receptor interaction
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04020 Calcium signaling pathway
    K05218  P2RX4; P2X purinoceptor 4
  Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K05218  P2RX4; P2X purinoceptor 4
Ion channels [BR:ko04040]
 Epithelial and related channels
  ATP-gated cation channel (P2X)
   K05218  P2RX4; P2X purinoceptor 4
BRITE hierarchy
Other DBs
Genes
HSA: 
5025(P2RX4)
PTR: 
452319(P2RX4)
PPS: 
100990374(P2RX4)
GGO: 
101148253(P2RX4)
PON: 
100458831(P2RX4)
NLE: 
100589361(P2RX4)
MCC: 
702536(P2RX4)
MCF: 
102120732(P2RX4)
CSAB: 
103239278(P2RX4)
RRO: 
104666272(P2RX4)
RBB: 
108529639(P2RX4)
CJC: 
100396434(P2RX4)
SBQ: 
101046432(P2RX4)
MMU: 
18438(P2rx4)
RNO: 
29659(P2rx4)
CGE: 
100752103(P2rx4)
NGI: 
103739074(P2rx4)
HGL: 
101723201(P2rx4)
CCAN: 
109699537(P2rx4)
OCU: 
100008720(P2RX4)
TUP: 
102475496(P2RX4)
CFA: 
448783(P2RX4)
AML: 
100477528(P2RX4)
UMR: 
103661274(P2RX4)
FCA: 
101080484(P2RX4)
PTG: 
102972163(P2RX4)
AJU: 
106967589(P2RX4)
BTA: 
338036(P2RX4)
BOM: 
102276211(P2RX4)
BIU: 
109571456(P2RX4)
PHD: 
102341711(P2RX4)
CHX: 
102173324(P2RX4)
OAS: 
101104013(P2RX4)
SSC: 
100157723(P2RX4)
CFR: 
102522360(P2RX4)
CDK: 
105102503(P2RX4)
BACU: 
103001338(P2RX4)
LVE: 
103091066(P2RX4)
ECB: 
100059626(P2RX4)
EPZ: 
103541695(P2RX4)
EAI: 
106842290(P2RX4)
MYB: 
102263539(P2RX4)
MYD: 
102753054(P2RX4)
HAI: 
109386080(P2RX4)
RSS: 
109448533(P2RX4)
PALE: 
102879399(P2RX4)
LAV: 
100670469(P2RX4)
MDO: 
100618270(P2RX4)
SHR: 
100923139(P2RX4)
OAA: 
100090378(P2RX4)
GGA: 
374166(P2RX4)
MGP: 
100543578(P2RX4)
CJO: 
107321119(P2RX4)
APLA: 
101791189(P2RX4)
ACYG: 
TGU: 
100232437(P2RX4)
GFR: 
102039359(P2RX4)
FAB: 
101815352(P2RX4)
PHI: 
102112929(P2RX4)
PMAJ: 
107211610(P2RX4)
CCW: 
104688704(P2RX4)
FPG: 
101919147(P2RX4)
FCH: 
102054376(P2RX4)
CLV: 
102085962(P2RX4)
AAM: 
106497654(P2RX4)
ASN: 
102376745(P2RX4)
AMJ: 
102564687(P2RX4)
PSS: 
102443940(P2RX4)
CMY: 
102931602(P2RX4)
CPIC: 
101943499(P2RX4)
ACS: 
100561452(p2rx4)
PVT: 
110083823(P2RX4)
PBI: 
103057916(P2RX4)
GJA: 
107115912(P2RX4)
XLA: 
398206(p2rx4.L)
XTR: 
100489363(p2rx4)
NPR: 
108787253(P2RX4)
DRE: 
259258(p2rx4a) 387301(p2rx4b)
SRX: 
SANH: 
SGH: 
IPU: 
108279151(p2rx4)
AMEX: 
103024165(p2rx4)
TRU: 
101070550(p2rx4)
TNG: 
LCO: 
104926383(p2rx4)
NCC: 
MZE: 
101483332(p2rx4)
OLA: 
101168548(p2rx4)
XMA: 
LCF: 
108878573(p2rx4)
BPEC: 
SASA: 
ELS: 
SFM: 
LCM: 
102346773(P2RX4)
CMK: 
103184313(p2rx4)
BFO: 
SPU: 
SKO: 
FCD: 
DPX: 
ISC: 
LGI: 
CRG: 
OBI: 
LAK: 
SMM: 
SHX: 
OVI: 
NVE: 
ADF: 
HMG: 
TAD: 
AQU: 
OLU: 
OTA: 
BPG: 
MBR: 
SRE: 
SMIN: 
v1.2.024239.t1(symbB.v1.2.024239.t1)
FCY: 
 » show all
TaxonomyKoalaUniProt
Reference
PMID:9016352
  Authors
Garcia-Guzman M, Soto F, Gomez-Hernandez JM, Lund PE, Stuhmer W
  Title
Characterization of recombinant human P2X4 receptor reveals pharmacological differences to the rat homologue.
  Journal
Mol Pharmacol 51:109-18 (1997)
DOI:10.1124/mol.51.1.109
  Sequence
[hsa:5025]

KEGG   ORTHOLOGY: K05219Help
Entry
K05219                      KO                                     

Name
P2RX5
Definition
P2X purinoceptor 5
Pathway
Calcium signaling pathway
Neuroactive ligand-receptor interaction
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04020 Calcium signaling pathway
    K05219  P2RX5; P2X purinoceptor 5
  Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K05219  P2RX5; P2X purinoceptor 5
Ion channels [BR:ko04040]
 Epithelial and related channels
  ATP-gated cation channel (P2X)
   K05219  P2RX5; P2X purinoceptor 5
BRITE hierarchy
Other DBs
Genes
HSA: 
5026(P2RX5)
PTR: 
454434(P2RX5)
PPS: 
100987979(P2RX5)
GGO: 
101151906(P2RX5)
PON: 
100449349(P2RX5)
NLE: 
100594071(P2RX5)
MCC: 
721476(P2RX5)
MCF: 
102142153(P2RX5)
CSAB: 
103242166(P2RX5)
RRO: 
104677252(P2RX5)
RBB: 
108523100(P2RX5)
CJC: 
100411168(P2RX5)
SBQ: 
101035805(P2RX5)
MMU: 
94045(P2rx5)
RNO: 
113995(P2rx5)
CGE: 
100772284(P2rx5)
NGI: 
103752018(P2rx5)
HGL: 
101725587(P2rx5)
CCAN: 
109694457(P2rx5)
OCU: 
100355479(P2RX5)
TUP: 
102500710(P2RX5)
CFA: 
448785(P2RX5)
AML: 
100464947(P2RX5)
UMR: 
103667128(P2RX5)
FCA: 
101080493(P2RX5)
PTG: 
102961352(P2RX5)
AJU: 
106987360(P2RX5)
BTA: 
338035(P2RX5)
BOM: 
102288136(P2RX5)
BIU: 
109573593(P2RX5)
PHD: 
102344393(P2RX5)
CHX: 
102179517(P2RX5)
OAS: 
101110429(P2RX5)
SSC: 
100519563(P2RX5)
CFR: 
102517645(P2RX5)
CDK: 
105095750(P2RX5)
BACU: 
103011151(P2RX5)
LVE: 
103074692(P2RX5)
EPZ: 
103562926(P2RX5)
EAI: 
106825658(P2RX5)
MYB: 
102261486(P2RX5)
MYD: 
102754625(P2RX5)
HAI: 
109391881(P2RX5)
RSS: 
109453781(P2RX5)
PALE: 
102879785(P2RX5)
LAV: 
100674260(P2RX5)
MDO: 
SHR: 
100923604(P2RX5)
OAA: 
100077854(P2RX5)
GGA: 
395507(P2RX5)
MGP: 
100548411(P2RX5)
CJO: 
107322399(P2RX5)
APLA: 
101797369(P2RX5)
ACYG: 
106045782(P2RX5)
TGU: 
100226199(P2RX5)
GFR: 
102040218(P2RX5)
FAB: 
101821279(P2RX5)
PHI: 
102105994(P2RX5)
PMAJ: 
107212709(P2RX5)
CCW: 
104691032(P2RX5)
FPG: 
101911936(P2RX5)
FCH: 
102046370(P2RX5)
CLV: 
102098338(P2RX5)
AAM: 
106493765(P2RX5)
ASN: 
102387044(P2RX5)
AMJ: 
102563213(P2RX5)
PSS: 
102446429(P2RX5)
CMY: 
102934766(P2RX5)
CPIC: 
101945661(P2RX5)
PVT: 
110087400(P2RX5)
PBI: 
103065205(P2RX5)
GJA: 
107106701(P2RX5)
XLA: 
108707930(p2rx5.L) 108709191(p2rx5.S)
XTR: 
100485445(p2rx5)
NPR: 
108787949(P2RX5)
DRE: 
373879(p2rx5) 387299(p2rx8)
SRX: 
SANH: 
SGH: 
IPU: 
AMEX: 
TRU: 
101068098(p2rx5)
TNG: 
LCO: 
NCC: 
MZE: 
OLA: 
XMA: 
CSEM: 
LCF: 
HCQ: 
BPEC: 
SASA: 
ELS: 
105030979(p2rx5)
SFM: 
LCM: 
102361591(P2RX5)
FCD: 
 » show all
TaxonomyKoalaUniProt
Reference
PMID:9414125
  Authors
Le KT, Paquet M, Nouel D, Babinski K, Seguela P
  Title
Primary structure and expression of a naturally truncated human P2X ATP receptor subunit from brain and immune system.
  Journal
FEBS Lett 418:195-9 (1997)
DOI:10.1016/S0014-5793(97)01380-X
  Sequence
[hsa:5026]

KEGG   ORTHOLOGY: K05220Help
Entry
K05220                      KO                                     

Name
P2RX7
Definition
P2X purinoceptor 7
Pathway
Calcium signaling pathway
Neuroactive ligand-receptor interaction
NOD-like receptor signaling pathway
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04020 Calcium signaling pathway
    K05220  P2RX7; P2X purinoceptor 7
  Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K05220  P2RX7; P2X purinoceptor 7
 Organismal Systems
  Immune system
   04621 NOD-like receptor signaling pathway
    K05220  P2RX7; P2X purinoceptor 7
Ion channels [BR:ko04040]
 Epithelial and related channels
  ATP-gated cation channel (P2X)
   K05220  P2RX7; P2X purinoceptor 7
BRITE hierarchy
Other DBs
Genes
HSA: 
5027(P2RX7)
PTR: 
452318(P2RX7)
PPS: 
100990943(P2RX7)
GGO: 
101146233(P2RX7)
PON: 
100458463(P2RX7)
NLE: 
100588362(P2RX7)
MCC: 
699455(P2RX7)
MCF: 
101865374(P2RX7)
CSAB: 
103239277(P2RX7)
RRO: 
104666270(P2RX7)
RBB: 
108529640(P2RX7)
CJC: 
100393329(P2RX7)
SBQ: 
101046955(P2RX7)
MMU: 
18439(P2rx7)
RNO: 
29665(P2rx7)
CGE: 
100765617(P2rx7)
NGI: 
103739075(P2rx7)
HGL: 
101721795(P2rx7)
CCAN: 
OCU: 
100351535(P2RX7)
TUP: 
102495976(P2RX7)
CFA: 
448778(P2RX7)
AML: 
100477277(P2RX7)
UMR: 
103661168(P2RX7)
FCA: 
101097922(P2RX7)
PTG: 
102949692(P2RX7)
AJU: 
106967541(P2RX7)
BTA: 
286814(P2RX7)
BOM: 
BIU: 
109571559(P2RX7)
PHD: 
102341350(P2RX7)
CHX: 
102174145(P2RX7)
OAS: 
101103842(P2RX7)
SSC: 
497623(P2RX7)
CFR: 
102505603(P2RX7)
CDK: 
105102501(P2RX7)
BACU: 
102999858(P2RX7)
LVE: 
103091614(P2RX7)
ECB: 
100058464(P2RX7)
EPZ: 
103541440(P2RX7)
EAI: 
106842288(P2RX7)
MYD: 
102751346(P2RX7)
HAI: 
109386041(P2RX7)
RSS: 
109448531(P2RX7)
PALE: 
102879645(P2RX7)
LAV: 
100677782(P2RX7)
MDO: 
SHR: 
GGA: 
771952(P2RX7)
MGP: 
100543425(P2RX7)
CJO: 
107321117(P2RX7)
APLA: 
101801281(P2RX7)
ACYG: 
FPG: 
101919310(P2RX7)
FCH: 
102054201(P2RX7)
AAM: 
ASN: 
102380463(P2RX7)
AMJ: 
102564452(P2RX7)
PSS: 
102462065(P2RX7)
CMY: 
102932507(P2RX7)
CPIC: 
101943226(P2RX7)
ACS: 
100561255(p2rx7)
PVT: 
110083862(P2RX7)
PBI: 
103058161(P2RX7)
GJA: 
107115894(P2RX7)
XLA: 
398286(p2rx7.L)
XTR: 
NPR: 
DRE: 
387298(p2rx7)
SRX: 
SANH: 
SGH: 
TRU: 
101079170(p2rx7)
LCO: 
104934856(p2rx7)
MZE: 
101482732(p2rx7)
XMA: 
102233539(p2rx7)
LCF: 
HCQ: 
BPEC: 
110170698(p2rx7)
SASA: 
ELS: 
SFM: 
LCM: 
102352362(P2RX7)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Cheewatrakoolpong B, Gilchrest H, Anthes JC, Greenfeder S
  Title
Identification and characterization of splice variants of the human P2X7 ATP channel.
  Journal
Biochem Biophys Res Commun 332:17-27 (2005)
DOI:10.1016/j.bbrc.2005.04.087
  Sequence
[hsa:5027]

KEGG   ORTHOLOGY: K05221Help
Entry
K05221                      KO                                     

Name
P2RX6, P2RXL1
Definition
P2X purinoceptor 6
Pathway
Calcium signaling pathway
Neuroactive ligand-receptor interaction
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04020 Calcium signaling pathway
    K05221  P2RX6, P2RXL1; P2X purinoceptor 6
  Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K05221  P2RX6, P2RXL1; P2X purinoceptor 6
Ion channels [BR:ko04040]
 Epithelial and related channels
  ATP-gated cation channel (P2X)
   K05221  P2RX6, P2RXL1; P2X purinoceptor 6
BRITE hierarchy
Other DBs
Genes
HSA: 
9127(P2RX6)
PTR: 
PPS: 
100976042(P2RX6)
GGO: 
PON: 
100445728(P2RX6)
NLE: 
100588488(P2RX6)
MCC: 
695841(P2RX6)
MCF: 
102129289(P2RX6)
CSAB: 
RRO: 
104666856(P2RX6)
RBB: 
108536090(P2RX6)
CJC: 
100397824(P2RX6)
SBQ: 
MMU: 
18440(P2rx6)
RNO: 
25041(P2rx6)
CGE: 
100757216(P2rx6)
NGI: 
103741467(P2rx6)
HGL: 
101702346(P2rx6)
CCAN: 
109684367(P2rx6)
OCU: 
100349719(P2RX6)
TUP: 
102480592(P2RX6)
CFA: 
486436(P2RX6)
AML: 
100471072(P2RX6)
UMR: 
103669295(P2RX6)
FCA: 
PTG: 
102951525(P2RX6)
AJU: 
BTA: 
618262(P2RX6)
BOM: 
102280240(P2RX6)
BIU: 
109571268(P2RX6)
PHD: 
102318079(P2RX6)
CHX: 
102173383(P2RX6)
OAS: 
101118819(P2RX6)
SSC: 
100515342(P2RX6)
CFR: 
102514060(P2RX6)
CDK: 
105095226(P2RX6)
BACU: 
103018925(P2RX6)
LVE: 
103079189(P2RX6)
ECB: 
100051842(P2RX6)
EPZ: 
EAI: 
MYB: 
102250561(P2RX6)
MYD: 
102760075(P2RX6)
HAI: 
109376246(P2RX6)
RSS: 
109461467(P2RX6)
PALE: 
102894381(P2RX6)
LAV: 
100661194(P2RX6)
SHR: 
105749675(P2RX6)
OAA: 
100084240(P2RX6)
GGA: 
429367(P2RX6)
MGP: 
100547282(P2RX6)
CJO: 
107321406(P2RX6)
APLA: 
101790078(P2RX6)
ACYG: 
106047463(P2RX6)
TGU: 
100217680(P2RX6)
GFR: 
102044532(P2RX6)
FAB: 
101811989(P2RX6)
PHI: 
102100542(P2RX6)
PMAJ: 
107211738(P2RX6)
CCW: 
FPG: 
101912387(P2RX6)
FCH: 
102056684(P2RX6)
CLV: 
102087218(P2RX6)
AAM: 
106494506(P2RX6)
ACS: 
100555164(p2rx6)
PVT: 
110081946(P2RX6)
PBI: 
103054093(P2RX6)
GJA: 
107126087(P2RX6)
XTR: 
105948055(p2rx6)
NPR: 
LCM: 
 » show all
TaxonomyKoalaUniProt
Reference
PMID:9242461
  Authors
Urano T, Nishimori H, Han H, Furuhata T, Kimura Y, Nakamura Y, Tokino T
  Title
Cloning of P2XM, a novel human P2X receptor gene regulated by p53.
  Journal
Cancer Res 57:3281-7 (1997)
  Sequence
[hsa:9127]

KEGG   ORTHOLOGY: K04809Help
Entry
K04809                      KO                                     

Name
CHRNA7
Definition
nicotinic acetylcholine receptor alpha-7
Pathway
Calcium signaling pathway
Neuroactive ligand-receptor interaction
Cholinergic synapse
Nicotine addiction
Chemical carcinogenesis
Disease
H01877  
Chromosome 15q13.3 microdeletion syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04020 Calcium signaling pathway
    K04809  CHRNA7; nicotinic acetylcholine receptor alpha-7
  Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K04809  CHRNA7; nicotinic acetylcholine receptor alpha-7
 Organismal Systems
  Nervous system
   04725 Cholinergic synapse
    K04809  CHRNA7; nicotinic acetylcholine receptor alpha-7
 Human Diseases
  Cancers
   05204 Chemical carcinogenesis
    K04809  CHRNA7; nicotinic acetylcholine receptor alpha-7
  Substance dependence
   05033 Nicotine addiction
    K04809  CHRNA7; nicotinic acetylcholine receptor alpha-7
Ion channels [BR:ko04040]
 Cys-loop superfamily
  Acetylcholine (nicotinic)
   K04809  CHRNA7; nicotinic acetylcholine receptor alpha-7
BRITE hierarchy
Other DBs
Genes
HSA: 
1139(CHRNA7)
PTR: 
467639(CHRNA7)
PPS: 
100977072(CHRNA7)
GGO: 
PON: 
100456533(CHRNA7)
NLE: 
MCC: 
574230(CHRNA7)
MCF: 
102118754(CHRNA7)
CSAB: 
103245932(CHRNA7)
RRO: 
104668890(CHRNA7)
RBB: 
108531792(CHRNA7)
CJC: 
100385253(CHRNA7)
SBQ: 
101050618(CHRNA7)
MMU: 
11441(Chrna7)
RNO: 
25302(Chrna7)
CGE: 
NGI: 
HGL: 
101720562(Chrna7)
CCAN: 
OCU: 
100342986(CHRNA7)
TUP: 
102493539(CHRNA7)
CFA: 
488696(CHRNA7)
AML: 
100469287(CHRNA7)
UMR: 
103659968(CHRNA7)
FCA: 
751113(CHRNA7)
PTG: 
102955772(CHRNA7)
AJU: 
BTA: 
282178(CHRNA7)
BOM: 
102272741(CHRNA7)
BIU: 
109575699(CHRNA7)
PHD: 
CHX: 
102179705(CHRNA7)
OAS: 
101113104(CHRNA7)
SSC: 
100415931(CHRNA7)
CFR: 
102524002(CHRNA7)
CDK: 
BACU: 
LVE: 
ECB: 
100060521(CHRNA7)
EPZ: 
EAI: 
106834056(CHRNA7)
MYB: 
102246452(CHRNA7)
MYD: 
102764475(CHRNA7)
HAI: 
RSS: 
109459063(CHRNA7)
PALE: 
102889630(CHRNA7)
LAV: 
100656157(CHRNA7)
MDO: 
SHR: 
100930913(CHRNA7)
OAA: 
GGA: 
374001(CHRNA7) 396120(CHRNA8)
MGP: 
100543989(CHRNA7)
CJO: 
APLA: 
ACYG: 
TGU: 
GFR: 
FAB: 
PHI: 
PMAJ: 
CCW: 
FPG: 
FCH: 
CLV: 
AAM: 
106496424(CHRNA7)
ASN: 
AMJ: 
PSS: 
CMY: 
CPIC: 
ACS: 
PVT: 
PBI: 
GJA: 
XLA: 
XTR: 
NPR: 
DRE: 
100537531(si:ch73-380n15.2) 394199(chrna7) 566141(si:ch211-39a7.1)
SRX: 
SANH: 
SGH: 
IPU: 
AMEX: 
TRU: 
446018(a7b) 446024(Fr_a8a) 446091(Fr_a8b)
TNG: 
LCO: 
NCC: 
MZE: 
OLA: 
XMA: 
CSEM: 
LCF: 
HCQ: 
BPEC: 
SASA: 
ELS: 
SFM: 
LCM: 
CMK: 
FCD: 
CRG: 
LAK: 
 » show all
TaxonomyKoalaUniProt
Reference
PMID:8145738
  Authors
Peng X, Katz M, Gerzanich V, Anand R, Lindstrom J
  Title
Human alpha 7 acetylcholine receptor: cloning of the alpha 7 subunit from the SH-SY5Y cell line and determination of pharmacological properties of native receptors and functional alpha 7 homomers expressed in Xenopus oocytes.
  Journal
Mol Pharmacol 45:546-54 (1994)
  Sequence
[hsa:1139]
Reference
  Authors
Papke RL, Horenstein NA, Kulkarni AR, Stokes C, Corrie LW, Maeng CY, Thakur GA
  Title
The activity of GAT107, an allosteric activator and positive modulator of alpha7 nicotinic acetylcholine receptors (nAChR), is regulated by aromatic amino acids that span the subunit interface.
  Journal
J Biol Chem 289:4515-31 (2014)
DOI:10.1074/jbc.M113.524603

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