KEGG   ORTHOLOGY: K05251Help
Entry
K05251                      KO                                     

Name
TSHB
Definition
thyroid stimulating hormone, beta
Pathway
Neuroactive ligand-receptor interaction
Thyroid hormone synthesis
Regulation of lipolysis in adipocytes
Autoimmune thyroid disease
Disease
H00250  
Congenital nongoitrous hypothyroidism (CHNG)
H01699  
Isolated TSH deficiency
H01700  
Hypopituitarism
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K05251  TSHB; thyroid stimulating hormone, beta
 Organismal Systems
  Endocrine system
   04923 Regulation of lipolysis in adipocyte
    K05251  TSHB; thyroid stimulating hormone, beta
   04918 Thyroid hormone synthesis
    K05251  TSHB; thyroid stimulating hormone, beta
 Human Diseases
  Immune diseases
   05320 Autoimmune thyroid disease
    K05251  TSHB; thyroid stimulating hormone, beta
BRITE hierarchy
Genes
HSA: 
7252(TSHB)
PTR: 
748248(TSHB)
PPS: 
100967932(TSHB)
GGO: 
101149441(TSHB)
PON: 
100443696(TSHB)
NLE: 
100593224(TSHB)
MCC: 
709374(TSHB)
MCF: 
102135350(TSHB)
CSAB: 
103224162(TSHB)
RRO: 
104669072(TSHB)
RBB: 
108528124(TSHB)
CJC: 
100385359(TSHB)
SBQ: 
101038043(TSHB)
MMU: 
22094(Tshb)
RNO: 
25653(Tshb)
CGE: 
100751072(Tshb)
NGI: 
103734942(Tshb)
HGL: 
101720907(Tshb)
CCAN: 
109682241(Tshb)
OCU: 
100302414(TSHB)
TUP: 
102501103(TSHB)
CFA: 
403973(TSHB)
AML: 
100469951(TSHB)
UMR: 
103669418(TSHB)
FCA: 
554350(TSHB)
PTG: 
102951543(TSHB)
AJU: 
106969661(TSHB)
BTA: 
281552(TSHB)
BOM: 
102287977(TSHB)
BIU: 
109555886(TSHB)
PHD: 
102343915(TSHB)
CHX: 
102185966(TSHB)
OAS: 
101104284(TSHB)
SSC: 
397658(TSHB)
CFR: 
102511444(TSHB)
CDK: 
105089625(TSHB)
BACU: 
103002421(TSHB)
LVE: 
103084958(TSHB)
ECB: 
100034188(TSHB)
EPZ: 
103547739(TSHB)
EAI: 
106835710(TSHB)
MYB: 
102247015(TSHB)
MYD: 
102761777(TSHB)
HAI: 
109392811(TSHB)
RSS: 
109446782(TSHB)
PALE: 
102887106(TSHB)
LAV: 
100660279(TSHB)
MDO: 
503501(TSHB)
SHR: 
100927019(TSHB)
OAA: 
100074530(TSHB)
GGA: 
395937(TSHB)
MGP: 
100546526(TSHB)
CJO: 
107324819(TSHB)
APLA: 
101804542(TSHB)
ACYG: 
106041291(TSHB)
TGU: 
100220136(TSHB)
GFR: 
102040289(TSHB)
FAB: 
101818412(TSHB)
PHI: 
102111041(TSHB)
PMAJ: 
107214721(TSHB)
CCW: 
104692414(TSHB)
FPG: 
101920577(TSHB)
FCH: 
102055291(TSHB)
CLV: 
102098073(TSHB)
AAM: 
106485256(TSHB)
ASN: 
102380596(TSHB)
AMJ: 
102568447(TSHB)
PSS: 
102449915(TSHB)
CMY: 
102944542(TSHB)
CPIC: 
101951522(TSHB)
ACS: 
100552987(tshb)
PVT: 
110072381(TSHB)
PBI: 
103057906(TSHB)
GJA: 
107111993(TSHB)
XLA: 
100381085(tshb.S) 108707690(tshb.L)
XTR: 
100496349(tshb)
NPR: 
108799084(TSHB)
DRE: 
353223(tshba)
SRX: 
SANH: 
SGH: 
IPU: 
TRU: 
101067051(tshb) 101071898(fshb)
TNG: 
LCO: 
NCC: 
MZE: 
OLA: 
XMA: 
CSEM: 
LCF: 
HCQ: 
BPEC: 
SASA: 
ELS: 
SFM: 
LCM: 
CMK: 
 » show all
TaxonomyKoalaUniProt
Reference
PMID:1320763
  Authors
Dumont JE, Lamy F, Roger P, Maenhaut C
  Title
Physiological and pathological regulation of thyroid cell proliferation and differentiation by thyrotropin and other factors.
  Journal
Physiol Rev 72:667-97 (1992)

KEGG   ORTHOLOGY: K08522Help
Entry
K08522                      KO                                     

Name
CGA
Definition
glycoprotein hormones, alpha polypeptide
Pathway
Neuroactive ligand-receptor interaction
GnRH signaling pathway
Ovarian steroidogenesis
Prolactin signaling pathway
Thyroid hormone synthesis
Regulation of lipolysis in adipocytes
Autoimmune thyroid disease
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K08522  CGA; glycoprotein hormones, alpha polypeptide
 Organismal Systems
  Endocrine system
   04923 Regulation of lipolysis in adipocyte
    K08522  CGA; glycoprotein hormones, alpha polypeptide
   04912 GnRH signaling pathway
    K08522  CGA; glycoprotein hormones, alpha polypeptide
   04913 Ovarian Steroidogenesis
    K08522  CGA; glycoprotein hormones, alpha polypeptide
   04917 Prolactin signaling pathway
    K08522  CGA; glycoprotein hormones, alpha polypeptide
   04918 Thyroid hormone synthesis
    K08522  CGA; glycoprotein hormones, alpha polypeptide
 Human Diseases
  Immune diseases
   05320 Autoimmune thyroid disease
    K08522  CGA; glycoprotein hormones, alpha polypeptide
BRITE hierarchy
Genes
HSA: 
1081(CGA)
PTR: 
462868(CGA)
PPS: 
GGO: 
PON: 
NLE: 
MCC: 
697859(CGA)
MCF: 
CSAB: 
RRO: 
RBB: 
CJC: 
SBQ: 
MMU: 
12640(Cga)
RNO: 
116700(Cga)
CGE: 
NGI: 
HGL: 
CCAN: 
OCU: 
TUP: 
CFA: 
403483(CGA)
AML: 
UMR: 
FCA: 
751819(CGA)
PTG: 
AJU: 
BTA: 
280749(CGA)
BOM: 
BIU: 
PHD: 
CHX: 
OAS: 
443538(CGA)
SSC: 
406869(CGA)
CFR: 
CDK: 
BACU: 
LVE: 
ECB: 
EPZ: 
EAI: 
MYB: 
MYD: 
RSS: 
PALE: 
LAV: 
MDO: 
554198(CGA)
SHR: 
OAA: 
GGA: 
421829(CGA)
MGP: 
CJO: 
APLA: 
ACYG: 
TGU: 
GFR: 
FAB: 
PHI: 
PMAJ: 
CCW: 
FPG: 
FCH: 
CLV: 
AAM: 
ASN: 
AMJ: 
PSS: 
CMY: 
CPIC: 
ACS: 
PVT: 
PBI: 
GJA: 
XLA: 
378681(cga.S) 432256(cga.L)
XTR: 
NPR: 
DRE: 
402987(cga)
SRX: 
SANH: 
SGH: 
IPU: 
TRU: 
TNG: 
LCO: 
NCC: 
MZE: 
OLA: 
XMA: 
CSEM: 
LCF: 
HCQ: 
BPEC: 
SASA: 
ELS: 
SFM: 
LCM: 
CMK: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Aussedat B, Fasching B, Johnston E, Sane N, Nagorny P, Danishefsky SJ
  Title
Total synthesis of the alpha-subunit of human glycoprotein hormones: toward fully synthetic homogeneous human follicle-stimulating hormone.
  Journal
J Am Chem Soc 134:3532-41 (2012)
DOI:10.1021/ja2111459

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