KEGG   ORTHOLOGY: K05412Help
Entry
K05412                      KO                                     

Name
CD80
Definition
CD80 antigen
Pathway
ko04514  Cell adhesion molecules (CAMs)
ko04620  Toll-like receptor signaling pathway
ko04672  Intestinal immune network for IgA production
ko04940  Type I diabetes mellitus
ko05320  Autoimmune thyroid disease
ko05322  Systemic lupus erythematosus
ko05323  Rheumatoid arthritis
ko05330  Allograft rejection
ko05332  Graft-versus-host disease
ko05416  Viral myocarditis
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signaling molecules and interaction
   04514 Cell adhesion molecules (CAMs)
    K05412  CD80; CD80 antigen
 Organismal Systems
  Immune system
   04620 Toll-like receptor signaling pathway
    K05412  CD80; CD80 antigen
   04672 Intestinal immune network for IgA production
    K05412  CD80; CD80 antigen
 Human Diseases
  Immune diseases
   05322 Systemic lupus erythematosus
    K05412  CD80; CD80 antigen
   05323 Rheumatoid arthritis
    K05412  CD80; CD80 antigen
   05320 Autoimmune thyroid disease
    K05412  CD80; CD80 antigen
   05330 Allograft rejection
    K05412  CD80; CD80 antigen
   05332 Graft-versus-host disease
    K05412  CD80; CD80 antigen
  Cardiovascular diseases
   05416 Viral myocarditis
    K05412  CD80; CD80 antigen
  Endocrine and metabolic diseases
   04940 Type I diabetes mellitus
    K05412  CD80; CD80 antigen
CD molecules [BR:ko04090]
 Proteins
  K05412  CD80; CD80 antigen (CD28 antigen ligand 1, B7-1 antigen)
BRITE hierarchy
Genes
HSA: 941(CD80)
PTR: 470892(CD80)
PPS: 100967832(CD80)
GGO: 101149580(CD80)
PON: 100441390(CD80)
NLE: 100602167(CD80)
MCC: 732518(CD80)
MCF: 102140078(CD80)
CSAB: 103228228(CD80)
RRO: 104657616(CD80)
RBB: 108541888(CD80)
CJC: 100392260(CD80)
SBQ: 101027898(CD80)
MMU: 12519(Cd80)
RNO: 25408(Cd80)
CGE: 100760030(Cd80)
NGI: 103742022(Cd80) 103742023
HGL: 101722924(Cd80)
CCAN: 109694534(Cd80)
OCU: 100009377(CD80)
TUP: 102479721(CD80)
CFA: 403765(CD80)
AML: 100480227(CD80)
UMR: 103678791(CD80)
ORO: 101363230(CD80)
FCA: 493786(CD80)
PTG: 102965184(CD80)
AJU: 106968282(CD80)
BTA: 407131(CD80)
BOM: 102277340(CD80)
BIU: 109576990(CD80)
PHD: 102338923(CD80)
CHX: 102168389(CD80)
OAS: 554317(CD80)
SSC: 397161(CD80)
CFR: 102524123(CD80)
CDK: 105090327(CD80)
BACU: 103003018(CD80)
LVE: 103085940(CD80)
OOR: 101280678(CD80)
ECB: 100071012(CD80)
EPZ: 103547416(CD80)
EAI: 106823733(CD80)
MYB: 102263238(CD80)
MYD: 102766781(CD80)
HAI: 109388468(CD80)
RSS: 109446367(CD80)
PALE: 102893707(CD80)
LAV: 100661159(CD80)
TMU: 101349613
MDO: 103097997(CD80)
SHR: 105749825(CD80)
GGA: 768950(CD80)
MGP: 100540827(CD80)
CJO: 107322032(CD80)
APLA: 101796029(CD80)
ACYG: 106039956(CD80)
TGU: 100223361(CD80)
GFR: 102041110(CD80)
FAB: 101805959(CD80)
PHI: 102100062(CD80)
PMAJ: 107210846(CD80)
CCW: 104689398(CD80)
FPG: 101919028(CD80)
FCH: 102049492(CD80)
CLV: 102092429
EGZ: 104123018(CD80)
AAM: 106490585(CD80)
ASN: 102385905(CD80)
AMJ: 102566599(CD80)
PSS: 102452898
CMY: 102931306(CD80)
CPIC: 101932205
ACS: 103278386(vtcn1)
PVT: 110088482
XLA: 108707787
XTR: 101733943(cd80)
DRE: 103908881
SRX: 107756209
SANH: 107670092
SGH: 107600809
IPU: 108277757
TRU: 105417042
NCC: 104966627
HCQ: 109525368
BPEC: 110174404
SASA: 106581370
 » show all
TaxonomyKoalaUniProt
Reference
PMID:2794510
  Authors
Freeman GJ, Freedman AS, Segil JM, Lee G, Whitman JF, Nadler LM
  Title
B7, a new member of the Ig superfamily with unique expression on activated and neoplastic B cells.
  Journal
J Immunol 143:2714-22 (1989)
  Sequence
[hsa:941]
Reference
  Authors
Chen L.
  Title
Co-inhibitory molecules of the B7-CD28 family in the control of T-cell immunity.
  Journal
Nat Rev Immunol 4:336-47 (2004)
DOI:10.1038/nri1349

KEGG   ORTHOLOGY: K05413Help
Entry
K05413                      KO                                     

Name
CD86
Definition
CD86 antigen
Pathway
ko04514  Cell adhesion molecules (CAMs)
ko04620  Toll-like receptor signaling pathway
ko04672  Intestinal immune network for IgA production
ko04940  Type I diabetes mellitus
ko05167  Kaposi's sarcoma-associated herpesvirus infection
ko05202  Transcriptional misregulation in cancer
ko05320  Autoimmune thyroid disease
ko05322  Systemic lupus erythematosus
ko05323  Rheumatoid arthritis
ko05330  Allograft rejection
ko05332  Graft-versus-host disease
ko05416  Viral myocarditis
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signaling molecules and interaction
   04514 Cell adhesion molecules (CAMs)
    K05413  CD86; CD86 antigen
 Organismal Systems
  Immune system
   04620 Toll-like receptor signaling pathway
    K05413  CD86; CD86 antigen
   04672 Intestinal immune network for IgA production
    K05413  CD86; CD86 antigen
 Human Diseases
  Cancers
   05202 Transcriptional misregulation in cancers
    K05413  CD86; CD86 antigen
  Immune diseases
   05322 Systemic lupus erythematosus
    K05413  CD86; CD86 antigen
   05323 Rheumatoid arthritis
    K05413  CD86; CD86 antigen
   05320 Autoimmune thyroid disease
    K05413  CD86; CD86 antigen
   05330 Allograft rejection
    K05413  CD86; CD86 antigen
   05332 Graft-versus-host disease
    K05413  CD86; CD86 antigen
  Cardiovascular diseases
   05416 Viral myocarditis
    K05413  CD86; CD86 antigen
  Endocrine and metabolic diseases
   04940 Type I diabetes mellitus
    K05413  CD86; CD86 antigen
  Infectious diseases
   05167 Kaposi's sarcoma-associated herpesvirus infection
    K05413  CD86; CD86 antigen
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   K05413  CD86; CD86 antigen
CD molecules [BR:ko04090]
 Proteins
  K05413  CD86; CD86 antigen (CD28 antigen ligand 2, B7-2 antigen)
BRITE hierarchy
Genes
HSA: 942(CD86)
PTR: 470900(CD86)
PPS: 100981251(CD86)
GGO: 101139275(CD86)
PON: 100432838(CD86)
NLE: 100601902(CD86)
MCC: 714390(CD86)
MCF: 102147235(CD86)
CSAB: 103228192(CD86)
RRO: 104667916(CD86)
RBB: 108541474(CD86)
CJC: 100407388(CD86)
SBQ: 101043934(CD86)
MMU: 12524(Cd86)
RNO: 56822(Cd86)
CGE: 100769382(Cd86)
NGI: 103741969(Cd86)
HGL: 101724342(Cd86)
CCAN: 109682249(Cd86)
OCU: 100008999(CD86)
TUP: 102478707(CD86)
CFA: 403764(CD86)
AML: 100483382(CD86)
UMR: 103678768(CD86)
ORO: 101386232(CD86)
FCA: 493704(CD86)
PTG: 102954528(CD86)
AJU: 106984101(CD86)
BTA: 414345(CD86)
BOM: 102275701(CD86)
BIU: 109554436(CD86)
PHD: 102327160(CD86)
CHX: 102184760(CD86)
OAS: 554318(CD86)
SSC: 397441(CD86)
CFR: 102521515(CD86)
CDK: 105090303(CD86)
BACU: 102998972(CD86)
LVE: 103068685(CD86)
OOR: 101289099(CD86)
ECB: 100060767(CD86)
EPZ: 103548423(CD86)
EAI: 106823736(CD86)
MYB: 102256413(CD86)
MYD: 102769844(CD86)
HAI: 109386841(CD86)
RSS: 109435884(CD86)
PALE: 102897001(CD86)
LAV: 100656594(CD86)
TMU: 101347585
MDO: 100018203(CD86)
SHR: 100926378(CD86)
OAA: 100086970(CD86)
GGA: 427944(CD86)
MGP: 100544635(CD86)
CJO: 107319044(CD86)
APLA: 101794331
ACYG: 106049293(CD86)
TGU: 100218239(CD86)
GFR: 102039756(CD86)
FAB: 101817056(CD86)
PHI: 102114181(CD86)
PMAJ: 107211329(CD86)
CCW: 104687108(CD86)
FPG: 101921390(CD86)
FCH: 102052355(CD86)
CLV: 102087829(CD86)
EGZ: 104126521(CD86)
AAM: 106497203(CD86)
ASN: 102369398(CD86)
AMJ: 102564301(CD86)
XTR: 100486350
LCO: 104940372(cd86)
NCC: 104952662
MZE: 101474078
OLA: 101164241
LCM: 102347855
 » show all
TaxonomyKoalaUniProt
Reference
PMID:7694153
  Authors
Azuma M, Ito D, Yagita H, Okumura K, Phillips JH, Lanier LL, Somoza C
  Title
B70 antigen is a second ligand for CTLA-4 and CD28.
  Journal
Nature 366:76-9 (1993)
DOI:10.1038/366076a0
  Sequence
[hsa:942]
Reference
  Authors
Collins M, Ling V, Carreno BM
  Title
The B7 family of immune-regulatory ligands.
  Journal
Genome Biol 6:223 (2005)
DOI:10.1186/gb-2005-6-6-223

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