KEGG   ORTHOLOGY: K05696Help
Entry
K05696                      KO                                     

Name
PTPN1, PTP1B
Definition
tyrosine-protein phosphatase non-receptor type 1 [EC:3.1.3.48]
Pathway
ko04520  Adherens junction
ko04910  Insulin signaling pathway
ko04931  Insulin resistance
Brite
KEGG Orthology (KO) [BR:ko00001]
 Cellular Processes
  Cellular community - eukaryotes
   04520 Adherens junction
    K05696  PTPN1, PTP1B; tyrosine-protein phosphatase non-receptor type 1
 Organismal Systems
  Endocrine system
   04910 Insulin signaling pathway
    K05696  PTPN1, PTP1B; tyrosine-protein phosphatase non-receptor type 1
 Human Diseases
  Endocrine and metabolic diseases
   04931 Insulin resistance
    K05696  PTPN1, PTP1B; tyrosine-protein phosphatase non-receptor type 1
Enzymes [BR:ko01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.48  protein-tyrosine-phosphatase
     K05696  PTPN1, PTP1B; tyrosine-protein phosphatase non-receptor type 1
Protein phosphatases and associated proteins [BR:ko01009]
 Protein Tyrosine phosphatases (PTPs)
  Class I PTPs (Classical)
   Non-receptor PTPs
    K05696  PTPN1, PTP1B; tyrosine-protein phosphatase non-receptor type 1
BRITE hierarchy
Other DBs
GO: 0004725
Genes
HSA: 5770(PTPN1)
PTR: 469970(PTPN1)
PPS: 100975196(PTPN1)
GGO: 101127138(PTPN1)
PON: 100172151(PTPN1)
NLE: 100603341(PTPN1)
MCC: 702016(PTPN1)
MCF: 101865216(PTPN1)
CSAB: 103244412(PTPN1)
RRO: 104678520(PTPN1)
RBB: 108539452(PTPN1)
CJC: 100387823(PTPN1)
SBQ: 101045896(PTPN1)
MMU: 19246(Ptpn1)
RNO: 24697(Ptpn1)
CGE: 100761071(Ptpn1)
NGI: 103735772(Ptpn1)
HGL: 101696680(Ptpn1)
CCAN: 109696597(Ptpn1)
OCU: 100354834(PTPN1)
TUP: 102484232(PTPN1)
CFA: 477263(PTPN1)
AML: 100481720(PTPN1)
UMR: 103669667(PTPN1)
ORO: 101378977(PTPN1)
FCA: 101099626(PTPN1)
PTG: 102965168(PTPN1)
AJU: 106980390(PTPN1)
BTA: 508658(PTPN1)
BOM: 102273630(PTPN1)
BIU: 109567547(PTPN1)
PHD: 102341839(PTPN1)
CHX: 102191814(PTPN1)
OAS: 101118209(PTPN1)
SSC: 396667(PTPN1)
CFR: 102516397(PTPN1)
CDK: 105087880(PTPN1)
BACU: 103020806(PTPN1)
LVE: 103086578(PTPN1)
OOR: 101288096(PTPN1)
ECB: 100052066(PTPN1)
EPZ: 103560571(PTPN1)
EAI: 106825676(PTPN1)
MYB: 102261669(PTPN1)
MYD: 102764615(PTPN1)
HAI: 109381866(PTPN1)
RSS: 109444586(PTPN1)
PALE: 102896636(PTPN1)
LAV: 100671219(PTPN1)
TMU: 101358370
MDO: 100028717(PTPN1)
OAA: 100077166(PTPN1)
GGA: 395688(PTPN1)
MGP: 100543385(PTPN1)
CJO: 107323063(PTPN1)
APLA: 101801370(PTPN1)
ACYG: 106041511(PTPN1)
TGU: 100224508(PTPN1)
GFR: 102037829(PTPN1)
FAB: 101808942(PTPN1)
PHI: 102110267(PTPN1)
PMAJ: 107213436(PTPN1)
CCW: 104687591(PTPN1)
FPG: 101923225(PTPN1)
FCH: 102055390(PTPN1)
CLV: 102084760(PTPN1)
EGZ: 104132199(PTPN1)
AAM: 106486459(PTPN1)
ASN: 102371275(PTPN1)
AMJ: 102564666(PTPN1)
PSS: 102445513(PTPN1)
CMY: 102946999(PTPN1)
CPIC: 101932653(PTPN1)
ACS: 100556985(ptpn1) 103279837
PVT: 110071802(PTPN1)
PBI: 103067846(PTPN1)
GJA: 107111128(PTPN1)
XLA: 108702596(ptpn1.S) 444514(ptpn1.L)
XTR: 549875(ptpn1)
NPR: 108795181(PTPN1)
DRE: 30081(ptpn1)
IPU: 108265420
AMEX: 103032056(ptpn1)
TRU: 101062679(ptpn1)
LCO: 104919931
NCC: 104963453
MZE: 101485042(ptpn1)
OLA: 101171745(ptpn1)
XMA: 102218352
PRET: 103467754
NFU: 107391300(ptpn1)
CSEM: 103385605
LCF: 108890482
HCQ: 109526882
BPEC: 110164566(ptpn1)
ELS: 105022331(ptpn1)
LCM: 102351595(PTPN1)
CMK: 103190931(ptpn1)
CIN: 100178520
SPU: 582421
SKO: 100373895
DME: Dmel_CG9181(Ptp61F)
DSI: Dsimw501_GD13480(Dsim_GD13480)
MDE: 101893385
AAG: 5572983
AME: 408900(GB14529)
BIM: 100746285
BTER: 100646948
SOC: 105198423
AEC: 105143554
ACEP: 105620650
PBAR: 105422012
HST: 105183777
CFO: 105259117
LHU: 105677476
PGC: 109860278
NVI: 100120226
TCA: 657787
DPA: 109547000
NVL: 108562196
BMOR: 100579140(Bmptp-Z)
PMAC: 106717068
PRAP: 110999947
API: 100167770
DNX: 107169675
ZNE: 110836001
FCD: 110858649
BMY: Bm1_36130
CRG: 105328654
MYI: 110466768
OBI: 106883419
LAK: 106155372
EPA: 110236524
HMG: 100212979
MUS: 103987681
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Sangwan V, Paliouras GN, Abella JV, Dube N, Monast A, Tremblay ML, Park M
  Title
Regulation of the Met receptor-tyrosine kinase by the protein-tyrosine phosphatase 1B and T-cell phosphatase.
  Journal
J Biol Chem 283:34374-83 (2008)
DOI:10.1074/jbc.M805916200
  Sequence
[hsa:5770]

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