KEGG   ORTHOLOGY: K05704Help
Entry
K05704                      KO                                     

Name
SRC
Definition
tyrosine-protein kinase Src [EC:2.7.10.2]
Pathway
ko01521  EGFR tyrosine kinase inhibitor resistance
ko01522  Endocrine resistance
ko04012  ErbB signaling pathway
ko04013  MAPK signaling pathway - fly
ko04015  Rap1 signaling pathway
ko04062  Chemokine signaling pathway
ko04137  Mitophagy - animal
ko04144  Endocytosis
ko04360  Axon guidance
ko04370  VEGF signaling pathway
ko04510  Focal adhesion
ko04520  Adherens junction
ko04530  Tight junction
ko04540  Gap junction
ko04611  Platelet activation
ko04625  C-type lectin receptor signaling pathway
ko04727  GABAergic synapse
ko04750  Inflammatory mediator regulation of TRP channels
ko04810  Regulation of actin cytoskeleton
ko04912  GnRH signaling pathway
ko04915  Estrogen signaling pathway
ko04917  Prolactin signaling pathway
ko04919  Thyroid hormone signaling pathway
ko04921  Oxytocin signaling pathway
ko04926  Relaxin signaling pathway
ko05100  Bacterial invasion of epithelial cells
ko05120  Epithelial cell signaling in Helicobacter pylori infection
ko05131  Shigellosis
ko05152  Tuberculosis
ko05161  Hepatitis B
ko05167  Kaposi's sarcoma-associated herpesvirus infection
ko05203  Viral carcinogenesis
ko05205  Proteoglycans in cancer
ko05219  Bladder cancer
ko05418  Fluid shear stress and atherosclerosis
Disease
H00978  Thrombocytopenia (THC)
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04015 Rap1 signaling pathway
    K05704  SRC; tyrosine-protein kinase Src
   04013 MAPK signaling pathway - fly
    K05704  SRC; tyrosine-protein kinase Src
   04012 ErbB signaling pathway
    K05704  SRC; tyrosine-protein kinase Src
   04370 VEGF signaling pathway
    K05704  SRC; tyrosine-protein kinase Src
 Cellular Processes
  Transport and catabolism
   04144 Endocytosis
    K05704  SRC; tyrosine-protein kinase Src
   04137 Mitophagy - animal
    K05704  SRC; tyrosine-protein kinase Src
  Cellular community - eukaryotes
   04510 Focal adhesion
    K05704  SRC; tyrosine-protein kinase Src
   04520 Adherens junction
    K05704  SRC; tyrosine-protein kinase Src
   04530 Tight junction
    K05704  SRC; tyrosine-protein kinase Src
   04540 Gap junction
    K05704  SRC; tyrosine-protein kinase Src
  Cell motility
   04810 Regulation of actin cytoskeleton
    K05704  SRC; tyrosine-protein kinase Src
 Organismal Systems
  Immune system
   04611 Platelet activation
    K05704  SRC; tyrosine-protein kinase Src
   04625 C-type lectin receptor signaling pathway
    K05704  SRC; tyrosine-protein kinase Src
   04062 Chemokine signaling pathway
    K05704  SRC; tyrosine-protein kinase Src
  Endocrine system
   04912 GnRH signaling pathway
    K05704  SRC; tyrosine-protein kinase Src
   04915 Estrogen signaling pathway
    K05704  SRC; tyrosine-protein kinase Src
   04917 Prolactin signaling pathway
    K05704  SRC; tyrosine-protein kinase Src
   04921 Oxytocin signaling pathway
    K05704  SRC; tyrosine-protein kinase Src
   04926 Relaxin signaling pathway
    K05704  SRC; tyrosine-protein kinase Src
   04919 Thyroid hormone signaling pathway
    K05704  SRC; tyrosine-protein kinase Src
  Nervous system
   04727 GABAergic synapse
    K05704  SRC; tyrosine-protein kinase Src
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    K05704  SRC; tyrosine-protein kinase Src
  Development
   04360 Axon guidance
    K05704  SRC; tyrosine-protein kinase Src
 Human Diseases
  Cancers
   05205 Proteoglycans in cancer
    K05704  SRC; tyrosine-protein kinase Src
   05203 Viral carcinogenesis
    K05704  SRC; tyrosine-protein kinase Src
   05219 Bladder cancer
    K05704  SRC; tyrosine-protein kinase Src
  Cardiovascular diseases
   05418 Fluid shear stress and atherosclerosis
    K05704  SRC; tyrosine-protein kinase Src
  Infectious diseases
   05120 Epithelial cell signaling in Helicobacter pylori infection
    K05704  SRC; tyrosine-protein kinase Src
   05131 Shigellosis
    K05704  SRC; tyrosine-protein kinase Src
   05152 Tuberculosis
    K05704  SRC; tyrosine-protein kinase Src
   05100 Bacterial invasion of epithelial cells
    K05704  SRC; tyrosine-protein kinase Src
   05161 Hepatitis B
    K05704  SRC; tyrosine-protein kinase Src
   05167 Kaposi's sarcoma-associated herpesvirus infection
    K05704  SRC; tyrosine-protein kinase Src
  Drug resistance
   01521 EGFR tyrosine kinase inhibitor resistance
    K05704  SRC; tyrosine-protein kinase Src
   01522 Endocrine resistance
    K05704  SRC; tyrosine-protein kinase Src
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     K05704  SRC; tyrosine-protein kinase Src
Protein kinases [BR:ko01001]
 Non-receptor tyrosine kinases
  SRC family
   K05704  SRC; tyrosine-protein kinase Src
Membrane trafficking [BR:ko04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Kinases and associated proteins
    K05704  SRC; tyrosine-protein kinase Src
 Endocytosis
  Clathrin-mediated endocytosis
   Kinases
    K05704  SRC; tyrosine-protein kinase Src
  Lipid raft mediated endocytosis
   Caveolin-mediated endocytosis
    K05704  SRC; tyrosine-protein kinase Src
  Macropinocytosis
   Kinases
    K05704  SRC; tyrosine-protein kinase Src
BRITE hierarchy
Other DBs
GO: 0004715
Genes
HSA: 6714(SRC)
PTR: 458229(SRC)
PPS: 100986423(SRC)
GGO: 101153251(SRC)
PON: 100436498(SRC)
NLE: 100602214(SRC) 100602548
MCC: 701057(SRC)
MCF: 102116225(SRC)
CSAB: 103246384(SRC)
RRO: 104655840(SRC)
RBB: 108519844(SRC)
CJC: 100386165(SRC)
SBQ: 101051959(SRC)
MMU: 20779(Src)
RNO: 83805(Src)
CGE: 100757188(Src)
NGI: 103752029(Src)
HGL: 101703827(Src)
CCAN: 109702281
OCU: 100341599(SRC)
TUP: 102491807(SRC)
CFA: 485864(SRC)
AML: 100474271(SRC)
UMR: 103669776(SRC)
ORO: 101368668(SRC)
FCA: 101100378(SRC)
PTG: 102968822(SRC)
AJU: 106974507(SRC)
BTA: 535742(SRC)
BOM: 102284506(SRC)
BIU: 109567428(SRC)
PHD: 102316335(SRC)
CHX: 102182890(SRC)
OAS: 101103084(SRC)
SSC: 100154503(SRC)
CFR: 102520048(SRC)
CDK: 105084996(SRC)
BACU: 103001801(SRC)
LVE: 103072342(SRC)
OOR: 101275089(SRC)
ECB: 100069870(SRC)
EPZ: 103560907(SRC)
EAI: 106835088(SRC)
MYB: 102247553(SRC)
MYD: 102769511(SRC)
HAI: 109377191(SRC)
RSS: 109457381(SRC)
PALE: 102891249(SRC)
LAV: 100675475(SRC)
TMU: 101342555
MDO: 100029391(SRC)
SHR: 100926529(SRC)
GGA: 396442(SRC)
MGP: 100547597(SRC)
CJO: 107322939(SRC)
APLA: 101797249(SRC)
ACYG: 106040941(SRC)
TGU: 100227812(SRC)
GFR: 102044186(SRC)
FAB: 101809008(SRC)
PHI: 102105012(SRC)
PMAJ: 107213277(SRC)
CCW: 104687766(SRC)
FPG: 101917743(SRC)
FCH: 102052372(SRC)
CLV: 102091546(SRC)
EGZ: 104132176(SRC)
AAM: 106493368
ASN: 102371874(SRC)
AMJ: 102567804(SRC)
PSS: 102462669(SRC)
CMY: 102939716(SRC)
CPIC: 101933235(SRC)
ACS: 100558035(src)
PVT: 110076767(SRC)
PBI: 103068084(SRC)
GJA: 107109696(SRC)
XLA: 373647(src.L) 380430(src.S)
XTR: 496893(src)
NPR: 108787987(SRC)
DRE: 325084(src)
IPU: 108255075 108276199(src)
TRU: 101065281 101078636(src)
NCC: 104942589 104966359(src)
OLA: 101164480 101173856(src)
HCQ: 109507451(src) 109513573
SFM: 108936597 108939128(src)
LCM: 102360542(SRC)
CMK: 103171906(src)
SPU: 590498(SFK5)
APLC: 110980160
DME: Dmel_CG7524(Src64B)
DSE: Dsec_GM13963(Dsec_Src64B)
DSI: Dsimw501_GD13245(Dsim_Src64B)
MDE: 101901281
AAG: 5565105
AME: 413464
BIM: 100750118
BTER: 100644180
SOC: 105197191
AEC: 105154274
ACEP: 105619285
PBAR: 105433933
HST: 105191289
CFO: 105252079
LHU: 105679049
PGC: 109856027
NVI: 100120276
TCA: 656565
DPA: 109541750
NVL: 108560093
BMOR: 101739984
PMAC: 106713731
PRAP: 111003061
PXY: 105388402
API: 100160649
DNX: 107167712
ZNE: 110831651
FCD: 110842479
TUT: 107361797
CEL: CELE_Y92H12A.1(src-1)
CBR: CBG22259(Cbr-src-1)
BMY: Bm1_36040
TSP: Tsp_11907
CRG: 105329816
MYI: 110463518
OBI: 106869883
LAK: 106155308
SPAR: SPRG_09612
VG: 1491925(src) 4097789(src)
 » show all
TaxonomyVtaxonomyKoalaUniProt
Reference
PMID:2440106
  Authors
Martinez R, Mathey-Prevot B, Bernards A, Baltimore D
  Title
Neuronal pp60c-src contains a six-amino acid insertion relative to its non-neuronal counterpart.
  Journal
Science 237:411-5 (1987)
DOI:10.1126/science.2440106
  Sequence
[mmu:20779]

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